Mast Cell Apoptosis: From the DNA to the Bedside

Allergie et Immunologie

Volumn 29, Issue 1, 1997, Pages 4-6

  Mekori, A Y ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

C kit; Mast Cell apoptosis; Stero ds

Indexed keywords

DNA FRAGMENT; INTERLEUKIN 3; PROTEIN BCL 2; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; APOPTOSIS; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; GAMMA RADIATION; HUMAN; MAST CELL; PHYSIOLOGY; RADIATION EXPOSURE; REVIEW;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; DNA FRAGMENTATION; GAMMA RAYS; HUMANS; INTERLEUKIN-3; MAST CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030635538     PISSN: 03979148     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. OKADA T., KIRSHENBAUM A., METCALFE DD. - Regulation of mast cell numbers within tissues. Allergy Clin. Immunol. News., 1995, 7, 51-55.
2. METCALFE DD., MEKORI YA and ROTTEM M. - Mast cell ontogeny and apoptosis. Experimental Dermatology, 1995, 4, 227-230.
3. COHEN JJ., DUKE RC., FADOK VA. - Apoptosis and programmed cell death in immunity. Annu. Rev. Immunol., 1992, 10, 267-293.
4. STEWART BW. - Mechanisms of apoptosis. Integration of genetic, biochemical and cellular indicators. J. Natl. Cancer Inst., 1994, 86: 267-293.
5. TSAI M., TAKASHI T., THOMPSON H et al. - Induction of mast cell proliferation, maturation and heparin synthesis by the rat c-kit ligand stem cell factor. Proc. Natl. Acad. Sci. U.S.A., 1991, 88, 6382-6386.
6. DASTYCH J., METCALFE DD. - Stem cell factor induces mast cell adhesion to fibronectin. J. Immunol., 1994, 152, 213-219.
7. MEKORI YA., OH CK., METCALFE DD. - IL-3 dependent mast cells undergo apoptosis on removal of IL-3 : Prevention of apoptosis by c-kit ligand. J. Immunol., 1993, 151, 3775-3784.
8. MEKORI YA., OH CK., METCALFE DD. - The role of c-kit and its ligand, stem cell factor, in mast cell apoptosis. Int. Arch. Allergy Immunol., 1995, 107, 136-138.
9. INEMURA A., TSAI M., ANDO A., WERSHIL BK., GALLI SJ. - The c-kit ligand promotes mast cell survival by suppressing apoptosis. Amer. J. Pathol. 1994, 144, 321-328.
10. HORIGOME K et al. - Effects of nerve growth factor on rat peritoneal mast cells. J. Biol. Chem., 1994, 269, 2695, 1994.
11. YEE NS., PAEK I., BESMER P. - Role of c-kit ligand in proliferation and suppression of apoptosis in mast cells. J. Exp. Med., 1994, 179, 1777-1787
12. MEKORI YA and METCALFE DD. - TGF- b prevents stem cell factor-mediated rescue of mast cells from apoptosis after IL-3 deprivation. J. Immunol., 1994, 153, 2194-2203.
13. DUBOIS CM., RUSCETTI FW., STANKOVA J., KELLER JR., TGF-b regulates c-kit message stability and cell surface protein expression in hemopoietic progenitors. Blood, 1994, 83, 3138-3145.
14. LONGLEY BJ., MORGANROTH GS., TYRRELL L., DING T., ANDERSON DM., WILLIAMS DE., HALABAN R. - Altered metabolism of mast cell growth factor (c-kit ligand) in cutaneous mastocytosis. N. Engl. J. Med., 1993, 328, 1302-1307.
15. FINOTTO S., MEKORI YA., METCALFE DD. - Glucocorticoids decrease tissue mast cell number by reducing the production of the c-kit ligand stem cell factor by resident cells : In vitro and in vivo evidence in murine systems. J. Clin. Invest. In press.