On the Relationships between the Strlatum and the Pedunculopontine Tegmental Nucleus

Critical Reviews in Neurobiology

Volumn 11, Issue 4, 1997, Pages 241-261

  Winn, Philip ^a   Brown, Verity J ^a   Inglis, Wendy L ^b  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UK   (United Kingdom)

Author keywords

Acetylcholine; Basal ganglia; Caudate putamen; Cortical re entrant systems; Limbic motor interface; Mesopontine tegmentum; Nucleus accumbens; Parkinson's disease

Indexed keywords

CAUDATE NUCLEUS; COGNITION; CORPUS STRIATUM; HISTOLOGY; HUMAN; LIMBIC SYSTEM; MOTIVATION; PATHOLOGY; PHYSIOLOGY; PUTAMEN; REINFORCEMENT; REVIEW; TEGMENTUM;

CAUDATE NUCLEUS; COGNITION; CORPUS STRIATUM; HUMANS; LIMBIC SYSTEM; MOTIVATION; PUTAMEN; REINFORCEMENT (PSYCHOLOGY); TEGMENTUM MESENCEPHALI;

EID: 0030634631     PISSN: 08920915     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevNeurobiol.v11.i4.10     Document Type: Article

References (115)

1. Kemp, J. M. and Powell, T. P. S., The corticostriate projection in the monkey, Brain, 93, 525, 1970.
2. DeLong, M. R. and Georgopolous, A. P., Motor functions of the basal ganglia, in Handbook of Physiology: The Nervous System, Vol. 2, part 2, Brookhart, J. M., Mountcastle, V. B., and Brooks, V. B., Eds., American Physiological Society, Bethesda, Maryland, 1981, 1017.
3. Alexander, G. E. and DeLong, M. R., Microstimulation of the primate neostriatum. II. Somatotopic organization of striatal microexcitable zones and their relation to neuronal response properties, J. Neurophysiol., 53, 1433, 1985.
4. Alexander, G. E., DeLong, M. R., and Strick, P. L., Parallel organization of functionally segregated circuits linking the basal ganglia and cortex, Ann. Rev. Neurosci., 9, 357, 1986.
5. Joel, D. and Weiner, I., The organization of the basal ganglia - thalamocortical circuits: open interconnected rather than closed segregated, Neuroscience, 63, 363, 1994.
6. Iacone, R. P., Lonser, R. R., Ulloth, J. E., and Shima, F., Postero-ventral pallidotomy in Parkinson's disease, J. Clin. Neurosci., 2, 140, 1995.
7. Rye, D. B., Turner, R. S., Vitek, J. L., Bakay, R. A. E., Crutcher, M. D., and DeLong, M. R., Anatomical investigations of the pallidotegmental pathway in monkey and man, in The Basal Ganglia V (Proceedings of the 5th Meeting of the International Basal Ganglia Society), Ohye, H., Kimura, M., and McKenzie, J. S., Eds., Plenum Press, New York, 1996.
8. Naito, A. and Kita, H., The cortico-pallidal projection in the rat: an anterograde tracing study with biotinylated dextran amine, Brain Res., 653, 251, 1994.
9. Semba, K., Aminergic and cholinergic afferents to REM sleep induction regions of the pontine reticular formation in the rat, J. Comp. Neural., 330, 543, 1993.
10. Semba, K., Reiner, P. B., and Fibiger, H. C., Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat, Neuroscience, 38, 643, 1990.
11. Steriade, M. and McCarley, R. W., Brainstem Control of Wakefulness and Sleep, Plenum Press, New York, 1990.
12. Mogenson, G. J. and Wu, M., Differential effects on locomotor activity of injections of procaine into mediodorsal thalamus and pedunculopontine nucleus, Brain Res. Bull., 20, 241, 1988.
13. Mogenson, G. J., Wu, M., and Tsai, C. T., Subpallidal-pedunculopontine projections but not subpallidal-mediodorsal thalamus projections contribute to spontaneous exploratory locomotor activity, Brain Res., 485, 396, 1989.
14. Shik, M. L., Severin, F. V., and Orlovskii, G. N., Control of walking and running by means of electrical stimulation of the mid-brain, Biophysics, 11, 756, 1966.
15. Nauta, W. J. H. and Domesick, V. B., The anatomy of the extrapyramidal system, in Dopaminergic Ergot Derivatives and Motor Functions (Wenner-Gren Center International Symposium Series, vol. 31), Fuxe, K. and Calne, D. B., Eds., Pergamon Press, New York, 1979, 3.
16. Bjorklund, A. and Lindvall, O., Catecholaminergic brain stem regulatory systems, in Handbook of Physiology: The Nervous System, vol. 4, Mountcastle, V. B., Bloom, F. E., and Geiger, S. R., Eds., American Physiological Society, Bethesda, Maryland, 1986, 155.
17. Zahm, D. S. and Heimer, L., Specificity in the efferent projections of the nucleus accumbens in the rat: comparison of the rostral pole projection patterns with those of the core and shell, J. Comp. Neural, 327, 220, 1993.
18. Mogenson, G. J., Jones, D. L., and Yim, C. Y., From motivation to action: functional interface between the limbic system and the motor system, Prog. Neurobiol., 14, 69, 1980.
19. Willner, P., Ahlenius, S., Muscat, R., and Scheel-Krüger, J., The mesolimbic dopamine system, in The Mesolimbic Dopamine System: From Motivation to Action, Willner, P. and Scheel-Krüger, J., Eds., John Wiley and Sons, Chichester, U.K., 1991, 3.
20. Carlson, N. R., Physiology of Behavior, 5th ed., Allyn and Bacon, Boston, 1995.
21. Bindra, D., A motivational view of learning, performance and behavior modification, Psychol. Rev., 81, 199, 1974.
22. Mesulam, M. M., Mufson, E. J., Wainer, B. H., and Levey, A. I., Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Chl-Ch6), Neuroscience, 10, 1185, 1983.
23. Rye, D. B., Saper, C. B., Lee, H. J., and Wainer, B. H., Pedunculopontine tegmental nucleus in the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum, J. Comp. Neural., 259, 483, 1987.
24. Ford, B., Holmes, C. J., Mainville, L., and Jones, B. E., GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus, J. Comp. Neurol., 363, 177, 1995.
25. Lavoie, B. and Parent A., Pedunculopontine nucleus in the squirrel monkey: distribution of cholinergic and monoaminergic neurons in the mesopontine tegmentum with evidence for the presence of glutamate in cholinergic neurons, J. Comp. Neurol., 344, 190, 1994.
26. Spann, B. M. and Grofova, I., Cholinergic and noncholinergic neurons in the rat pedunculopontine tegmental nucleus, Anat. Embryol., 186, 215, 1992.
27. Grofova, I. and Zhou, M., Nigral innervation of cholinergic and non-cholinergic cells in the rat mesopontine tegmentum: a double label EM study, Soc. Neurosci. Abstr., 19, 1433, 1993.
28. Honda, T. and Semba, K., An ultrastructural study of cholinergic and non-cholinergic neurons in the laterodorsal and pedunculopontine tegmental nuclei in the rat, Neuroscience, 68, 837, 1995.
29. Inglis, W. L. and Winn, P., The pedunculopontine tegmental nucleus: where the striatum meets the reticular formation, Prog. Neurobiol., 47, 1, 1995.
30. Medina, L. and Reiner, A., Distribution of choline acetyltransferase immunoreactivity in the pigeon brain, J. Comp. Neurol., 342, 497, 1994.
31. Kuenzel, W. J. and Masson, M., A Stereotaxic Atlas of the Brain of the Chick (Callus domesticus), The Johns Hopkins University Press, Baltimore, Maryland, 1988.
32. Vincent, S. R., Satoh, K., Armstrong, D. M., Panula, P., Vale, W., and Fibiger, H. C., Neuropeptides and NADPH-diaphorase activity in the ascending cholinergic reticular system of the rat, Neuroscience, 17, 167, 1986.
33. Hallanger, A. E., Levey, A. I., Lee, H. J., Rye, D. B., and Wainer, B. H., The origins of cholinergic and other subcortical afferents to the thalamus in the rat, J. Comp. Neurol, 262, 105, 1987.
34. Hallanger, A. E. and Wainer, B. H., Ascending projections from the pedunculopontine tegmental nucleus and the adjacent mesopontine tegmentum in the rat, J. Comp. Neurol, 274, 483, 1988.
35. Beninato, M. and Spencer, R. F., A cholinergic projection to the rat substantia nigra from the pedunculopontine tegmental nucleus, Brain Res., 412, 169, 1987.
36. Beninato, M. and Spencer, R. F., The cholinergic innervation of the rat substantia nigra, A light and electron microscopic immunohistochemical study, Exp. Brain Res., 72, 178, 1988.
37. Blaha, C. D. and Winn, P., Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmental nucleus-lesioned rats, J. Neurosci., 13, 1035, 1993.
38. Bolam, J. P., Francis, C. M., and Henderson, Z., Cholinergic input to dopaminergic neurons in the substantia nigra: a double immunocytochemical study, Neuroscience, 41, 483, 1991.
39. Gould, E., Woolf, N. J., and Butcher, L. L., Cholinergic projections to the substantia nigra from the pedunculopontine and laterodorsal tegmental nuclei, Neuroscience, 28, 611, 1989.
40. Lavole, B. and Parent, A., Pedunculopontine nucleus in the squirrel monkey: cholinergic and glutamatergic projections to the substantia nigra, J. Comp. Neurol, 344, 232, 1994.
41. Oakman, S. A., Paris, P. L., Kerr, P. E., Cozzari, C., and Hartman, B. K., Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area, J. Neurosci., 15, 5959, 1995.
42. Lee, H. J., Rye, D. B., Hallanger, A. E., Levey, A. I., and Wainer, B. H., Cholinergic vs. non-cholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei, J. Comp. Neurol., 275, 469, 1988.
43. Saper, C. B. and Loewy, A. D., Projections of the pedunculopontine tegmental nucleus in the rat: evidence for additional extrapyramidal circuitry, Brain Res., 252, 367, 1982.
44. Woolf, N. J. and Butcher, L. L., Cholinergic systems in the rat brain. III. Projections from the pontomesencephalic tegmentum to the thalamus, tec- turn, basal ganglia, and basal forebrain, Brain Res. Bull., 16, 603, 1986.
45. Bevan, M. D. and Bolam, J. P., Cholinergic, GABAergic and glutamate-enriched inputs from the mesopontine tegmentum to the subthalamic nucleus in the rat, J. Neurosci., 15, 7105, 1995.
46. Lavoie, B. and Parent, A., Pedunculopontine nucleus in the squirrel monkey: projections to the basal ganglia as revealed by anterograde tract-tracing methods, J. Comp. Neural., 344, 210, 1994.
47. Semba, K., Reiner, P. B., McGeer, E. G., and Fibiger, H. C., Brainstem afferents to the magnocellular basal forebrain studied by axonal transport, immunohistochemistry, and electrophysiology in the rat, J. Comp. Neural, 267, 433, 1988.
48. Roger, M. and Cadusseau, J., Afferents to the zona incerta in the rat: a combined retrograde and anterograde study, J. Comp. Neural., 241, 480, 1985.
49. Beninato, M. and Spencer, R. F., A cholinergic projection to the rat superior colliculus demonstrated by retrograde transport of horseradish peroxidase and choline acetyltransferase immunohistochemistry, J. Comp. Neural., 253, 525, 1986.
50. Yamamoto, K., Mamelak, A. N., Quattrochi, J. J., and Hobson, J. A., A cholinoceptive desynchronized sleep induction zone in the anterodorsal pontine tegmentum: locus of the sensitive region, Neuroscience, 39, 279, 1990.
51. Mitant, A., Keihachiro, I., Hallanger, A. E., Wainer, B. H., Kataoka, K., and McCarley, R. W., Cholinergic projections from the laterodorsal and pedunculopontine tegmental nuclei to the pontine gigantocellular tegmental field in the cat, Brain Res., 451, 397, 1988.
52. Rye, D. B., Lee, H. J., Saper, C. B., and Wainer, B. H., Medullary and spinal efferents of the pedunculopontine tegmental nucleus and adjacent mesopontine tegmentum in the rat, J. Comp. Neural., 269, 315, 1988.
53. Yasui, Y., Cechetto, D. F., and Saper, C. B., Evidence for a cholinergic projection from the pedunculopontine tegmental nucleus to the rostral ventrolateral medulla in the rat, Brain Res., 517, 19, 1990.
54. Skinner, R. D., Kinjo, N., Henderson, V., and Garcia-Rill, E., Locomotor projections from the pedunculopontine tegmental nucleus to the spinal cord, NeuroReport, 1, 183, 1990.
55. Skinner, R. D., Kinjo, N., Ishikawa, Y., Biederman, J. A., and Garcia-Rill, E., Locomotor projections from the pedunculopontine nucleus to the medioventral medulla, NeuroReport, 1, 207, 1990.
56. Parent, A. and Hazrati, L.-N., Functional anatomy of the basal ganglia. I. The cortico-basal gangliathalamo-cortical loop, Brain Res. Rev., 20, 91, 1995.
57. Berendse, H. W., Groenewegen, H. J., and Lohman, H. M., Compartmental distribution of ventral striatal neurons projecting to the mesencephalon in the rat, J. Neurosci., 12, 2079, 1992.
58. Groenewegen, H. J., Berendse, H. W., and Haber, S. N., Organization of the output of the ventral striatopallidal system in the rat: ventral pallidal efferents, Neuroscience, 57, 113, 1993.
59. Spann, B. M. and Grofova, I., Nigropedunculopontine projection in the rat: an anterograde tracing study with Phaseolus vulgaris-Leucoagglutinin (PHA-L), J. Comp. Neural., 311, 375, 1991.
60. Steininger, T. L., Rye, D. B., and Wainer, B. H., Afferent projections to the cholinergic pedunculopontine tegmental nucleus and adjacent midbrain extrapyramidal area in the albino rat. I. Retrograde tracing studies, J. Comp. Neural., 321, 515, 1992.
61. Heimer, L., Zahm, D. S., Churchill, L., Kalivas, P. W., and Wohltmann, C., Specificity in the projection patterns of accumbal core and shell in the rat, Neuroscience, 41, 89, 1991.
62. Semba, K. and Fibiger, H. C., Afferent connections of the laterodorsal and the pedunculopontine tegmental nuclei in the rat: a retro- and antero-grade transport and immunohistochemical study, J. Comp. Neural., 323, 387, 1992.
63. Honda, T. and Semba, K., Serotonergic synaptic input to cholinergic neurons in the rat mesopontine tegmentum, Brain Res., 647, 299, 1994.
64. Greene, R. W. and McCarley, R. W., Cholinergic transmission in the brainstem: implications for behavioural state control, in Brain Cholinergic Systems, Steriade, M. and Biesold, D., Eds., Oxford University Press, Oxford, 1990, 224.
65. Jones, B. E. and Yang, T. Z., The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat, J. Comp. Neural., 242, 56, 1985.
66. Jones, B. E., Immunohistochemical study of choline acetyltransferase-immunoreactive processes and cells innervating the pontomedullary reticular formation in the rat, J. Comp. Neural., 295, 485, 1990.
67. Mesulam, M.-M., Geula, C., Bothwell, M. A., and Hersh, L. B., Human reticular formation: cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons, J. Comp. Neural., 281, 611, 1989.
68. Smith, Y. and Shink, E., The pedunculopontine nucleus (PPN): a potential target for the convergence of information arising from different functional territories of the internal pallidum (Gpi) in primates, Soc. Neurosci. Abst., 21, 677, 1995.
69. Kang, Y. and Kitai, S. T., Electrophysiological properties of pedunculopontine neurons and their postsynaptic responses following stimulation of substantia nigra reticulata, Brain Res., 535, 79, 1990.
70. McCormick, D. A. and Prince, D. A., Acetylcholine induces burst firing in thalamic reticular neurons by activating a potassium conductance, Nature, 319., 402, 1986.
71. Steriade, M., Central core modulation of spontaneous oscillations and sensory transmission in thalamocortical systems, Curr. Opin. Neurobiol, 3, 619, 1993.
72. Steriade, M. and Llinás, R. R., The functional states of the thalamus and the associated neuronal interplay, Physiol. Rev., 68, 649, 1988.
73. Steriade, M., Datta, S., Paré, D., Oakson, G., and Curró Dossi, R., Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocoitical systems, J. Neurosci., 10, 2541, 1990.
74. Futami, T., Takakusaki, K., and Kitai, S. T., Glutamatergic and cholinergic inputs from the pedunculopontine tegmental nucleus to dopamine neurons in the substantia nigra pars compacta, Neurosci. Res., 21, 331, 1995.
75. Blaha, C. D., Allen, L. F., Das, S., Inglis, W. L., Latimer, M. P., Vincent, S. R., and Winn, P., Dopamine efflux in the nucleus accumbens following cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned and laterodorsal tegmental nucleus-lesioned rats, J. Neurosci., 16, 714, 1996.
76. Hernández-López, X., Góngora-Alfaro, J. L., Martínez-Fong, D., and Aceves J., A cholinergic input to the substantia nigra pars compacta increases striatal dopamine metabolism measured by in vivo voltammetry, Brain Res., 598, 114, 1992.
77. Kamondi, A., Williams, J. A., Hutcheon, B., and Reiner, P. B., Membrane properties of mesopontine cholinergic neurons studied with the whole-cell patchclamp technique: implications for behavioural state control, J. Neurophysiol., 68, 1359, 1992.
78. Leonard, C. S. and Llinás, L. L., Electrophysiology of mammalian pedunculopontine and laterodorsal tegmental neurons in vitro: Implications for the control of REM sleep, in Brain Cholinergic Systems, Steriade, M. and Biesold, D., Eds., Oxford University Press, Oxford, 1990, 205.
79. Leonard, C. S. and Llinás, R. R., Serotonergic and cholinergic inhibition of mesopontine cholinergic neurons controlling REM sleep: an in vitro electrophysiological study, Neuroscience, 59, 309, 1994.
80. Luebke, J. I., Greene, R. W., Semba, K., Kamondi, A., McCarley, R. W., and Reiner, P. B., Serotonin hyperpolarizes cholinergic low-threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro, Proc. Natl. Acad. Sci. U.S.A., 89, 743, 1992.
81. Williams, J. A. and Reiner, P. B., Noradrenaline hyperpolarizes identified rat mesopontine cholinergic neurons in vitro, J. Neurosci., 13, 3878, 1993.
82. Moriizumi, T. and Hattori, T., Separate neuronal projections of the rat globus pallidus projecting to the subthalamic nucleus, auditory cortex and pedunculopontine tegmental area, Neuroscience, 46, 701, 1992.
83. Inglis, W. L. and Semba, K., Ionotropic glutamate receptor subunit expression by cholinergic neurons in the rat pedunculopontine and laterodorsal tegmental nuclei, J. Comp. Neural., 368, 17, 1996.
84. Sakai, K. and Jouvet, M., Brain stem PGO-on cells projecting directly to the cat dorsal lateral geniculate nucleus, Brain Res., 194, 500, 1980.
85. Lydic, R. and Baghdoyan, H. A., Pedunculopontine stimulation alters respiration and increases ACh release in the pontine reticular formation, Am. J. Physiol., 264, R544, 1993.
86. Williams, J. A., Comisarow, J., Day, J., Fibiger, H. C., and Reiner, P. B., State-dependent release of acetylcholine in rat thalamus measured by in vivo microdialysis, J. Neurosci., 14, 5236, 1994.
87. Matsumura, M., Watanabe, K., and Ohye, C., Pedunculopontine tegmental nucleus - a single cell recording during active arm movement in monkeys, Soc. Neurosci. Abstr., 21, 412, 1995.
88. Brudzynski, S. M. and Mogenson, G. J., Association of the mesencephalic locomotor region with locomotor activity induced by injections of amphetamine into the nucleus accumbens, Brain Res., 334, 77, 1985.
89. Inglis, W. L., Allen, L. F., Whitelaw, R. B., Latimer, M. P., Brace, H. M., and Winn, P., An investigation into the role of the pedunculopontine tegmental nucleus in the mediation of locomotion and orofacial stereotypy induced by d-amphetamine and apomorphine in the rat, Neuroscience, 58, 817, 1994.
90. Olmstead, M. C. and Franklin, K. B. J., Lesions of the pedunculopontine tegmental nucleus block drug-induced reinforcement, but not amphetamine-induced locomotion, Brain Res., 638, 29, 1994.
91. Inglis, W. L., Dunbar, J. S., and Winn, P., Outflow from the nucleus accumbens to the pedunculopontine tegmental nucleus: a dissociation between locomotor activity and the acquisition of responding for conditioned reinforcement stimulated by d-amphetamine, Neuroscience, 62, 51, 1994.
92. Swerdlow, N. R. and Koob, G. F., Lesions of the dorsomedial nucleus of the thalamus, medial prefrontal cortex and pedunculopontine nucleus: effects on locomotor activity mediated by nucleus accumbens-ventral pallidal circuitry, Brain Res., 412, 233, 1987.
93. Bechara, A. and van der Kooy, D., The tegmental pedunculopontine nucleus: a brain-stem output of the limbic system critical for the conditioned place preferences produced by morphine and amphetamine, J. Neurosci., 9, 3400, 1989.
94. Bechara, A. and van der Kooy, D., A single brain stem substrate mediates the motivational effects of both opiates and food in nondeprived rats but not in deprived rats, Behav. Neurosci., 106, 351, 1992.
95. Lepore, M. and Franklin, K. B. J., N-methyl-D-aspartate lesions of the pedunculopontine nucleus block acquisition and impair maintenance of responding reinforced with brain stimulation, Neuroscience, 71, 147, 1996.
96. Yeomans, J. S., Mathur, A., and Tampakeras, M., Rewarding brain stimulation: role of tegmental cholinergic neurons that activate dopamine neurons, Behav. Neurosci., 107, 1077, 1993.
97. Alderson, H., Brown, V. J., Latimer, M. P., Robertson, A. H., and Winn, P., An examination of the perception of reward strength in rats with excitotoxic lesions of the pedunculopontine tegmental nucleus, manuscript submitted.
98. Inglis, W. L., Thakkar, M., Rainnie, D. G., Greene, R. W., McCarley, R. W., and Semba, K., Ibotenic acid lesions of the rat pedunculopontine or laterodorsal tegmental nucleus: effects on behavioural state control, Sleep Res., 24A, 217, 1995.
99. Mitchell, I. J., Clarke, C. E., Boyce, S., Robertson, R. G., Peggs, D., Sambrook, M. A., and Crossman, A. R., Neural mechanisms underlying Parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Neuroscience, 32, 213, 1989.
100. Oertel, W. H. and Mugnaini, E., Immunocytochemical studies of GABA-ergic neurons in rat basal ganglia and their relations to other neuronal systems, Neurosci. Lett., 47, 233, 1984.
101. Allen, L. F. and Winn, P., The pedunculopontine tegmental nucleus mediates orofacial behaviours stimulated by microinjections of d-amphetamine into rat ventrolateral caudate-putamen, Exp. Brain Res., 104, 262, 1995.
102. Brasted, P., Latimer, M. P., Winn, P., and Brown, V. J., An examination of reaction time performance in rats with excitotoxic lesions of the pedunculopontine tegmental nucleus, manuscript submitted.
103. Robbins, T. W. and Brown, V. J., The role of the striatum in the mental chronometry of action: a theoretical review, Rev. Neurosci., 2, 181, 1991.
104. 2 dopamine receptors in oral stereotypy induced by dopaminergic stimulation of the ventrolateral striatum, Neuroscience, 39, 59, 1990.
105. Mogoseanu, D., Smith, A. D., and Bolam, J. P., Monosynaptic innervation of trigeminal motor neurones involved in mastication by neurones of the parvicellular reticular formation, J. Comp. Neural., 336, 53, 1993.
106. Von Krosigk., M., Smith, Y., Bolam, J. P., and Smith, A. D., Synaptic organization of GABAergic inputs from the striatum and the globus pallidus onto neurons in the substantia nigra and retrorubral field which project to the medullary reticular formation, Neuroscience, 50, 531, 1992.
107. Dean, P. and Redgrave, P., Superior colliculus and visual neglect in rat and hamster. III. Functional implications, Brain Res. Rev., 8, 155, 1984.
108. Ingle, D. J., Prey selection by frogs and toads: a neuroethological model, in Handbook of Behavioral Neurobiology, vol. 6, Motivation, Satinoff, E. and Teitelbaum, P., Eds., Plenum Press, New York, 1983, 235.
109. Stefurak, T. L. and van der Kooy, D., Tegmental pedunculopontine lesions in rats decrease saccharin's rewarding effects but not its memory-improving effect, Behav. Neurosci., 108, 972, 1994.
110. Frith, C. D., The Cognitive Neuropsychology of Schizophrenia, Lawrence Erlbaum Associates, Hove, U.K., 1992.
111. Reading, P. and Dunnett, S., The effects of excitotoxic lesions of the nucleus accumbens on a matching to position task, Behav. Brain Res., 46, 17, 1991.
112. Brown, V. J. and Bowman, E. M., Discriminative cues indicating reward magnitude continue to determine reaction time of rats following lesions of the nucleus accumbens, Eur. J. Neurosci., 7, 2479, 1995.
113. McDonald, R. J. and White, N. M., A triple dissociation of memory systems: hippocampus, amygdala and dorsal striatum, Behav. Neurosci., 107, 3, 1993.
114. Vincent, S. R. and Kimura, H., Histochemical mapping of nitric oxide synthase in the rat brain, Neuroscience, 46, 755, 1992.
115. Nakamura, Y., Tokuno, H., Moriizumi, T., Kitao, Y., and Kudo, M., Monosynaptic nigral inputs to the pedunculopontine tegmental nucleus neurons which send their axons to the medial reticular formation in the medulla oblongata. An electron microscopic study in the cat, Neurosci. Lett., 103, 145, 1989.