GFAP and S100β expression in the cortex and hippocampus in response to mild cortical contusion

Journal of Neurotrauma

Volumn 14, Issue 10, 1997, Pages 729-738

  Hinkle, David A ^a   Baldwin, Stanley A ^b   Scheff, Stephen W ^b   Wise, Phyllis M ^c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Contusion; Gene expression; GFAP; Glial responses; Immunocytochemistry; mRNA; Protein; Rat; Reactiv e astrocyte; S100 ; Traumatic brain injury

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; PROTEIN S 100; RIBONUCLEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN CONTUSION; BRAIN CORTEX; CELL ACTIVATION; CELL DENSITY; CONTROLLED STUDY; GENE EXPRESSION; GLIOSIS; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; RAT; ANIMAL; BRAIN CONCUSSION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; NUCLEIC ACID HYBRIDIZATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN CONCUSSION; CEREBRAL CORTEX; GENE EXPRESSION; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NUCLEIC ACID HYBRIDIZATION; RATS; RATS, SPRAGUE-DAWLEY; RIBONUCLEASES; RNA, MESSENGER; S100 PROTEINS;

EID: 0030613843     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1997.14.729     Document Type: Article

References (39)

1. AUSUBEL, F.M., BRENT, R., KINGSTON, R.E., MOORE, D.D., SEIDMAN, J.G., SMITH, J.A., and STRUHL, K., eds. (1994). Current Protocols in Molecular Biology. Boston: John Wiley and Sons, Inc.
2. BALDWIN, S.A., and SCHEFF, S.W. (1996). Intermediate filament change in astrocytes following mild cortical contusion. Glia 16, 266-275.
3. BAROTTE, C., ECLANCHER, F., EBEL, A., LABOURDETTE, G., SENSENBRENNER, M., and WILL, B. (1989). Effects of basic fibroblast growth factor (bFGF) on choline acetyltransferase activity and astroglial reaction in adult rats after partial fimbria transection. Neurosci. Let. 101, 197-202.
4. BAUDIER, J., DELPHIN, C., GRUNWALD, D., KHOCHBIN, S., and LAWRENCE, J.J. (1992). Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein. P.N.A.S. USA 89, 11627-11631.
5. BIANCHI, R., GIAMBANCO, I., and DONATO, R. (1993). S-100 protein, but not calmodulin, binds to the glial fibrillary acidic protein and inhibits its polymerization in a Ca2+-dependent manner. J. Biol. Chem. 268, 12669-12674.
6. BONTHIUS, D.J., and STEWARD, O. (1993). Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition by MK-801. Brain Res. 618, 83-94.
7. BULLOCK, R., MAXWELL, W.L., GRAHAM, D.I., TEASDALE, G.M., and ADAMS, J.H. (1991). Glial swelling following human cerebral contusion: an ultrastructural study. J. Neurol., Neurosur. Psychiatry 54, 427-434.
8. CHOMCZYNSKI, P., and SACCHI, N. (1987). Single-step methods of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
9. DUFFY, P. (1983). Astrocytes: normal, reactive and neoplastic. New York: Raven Press.
10. EDDLESTON, M., and MUCKE, L. (1993). Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience 54, 15-36.
11. ENG, L.F. (1988). Astrocytic response to injury, in: Current Issues in Neural Regeneration. P. Reier, R. Bunge and F. Seil (eds.), Alan R. Liss: New York, pp. 247-255.
12. ENGELE, J., and BOHN, M.C. (1991). The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia. J. Neurosci. 11, 3070-3078.
13. FINKLESTEIN, S.P., APOSTOLIDES, P.J., CADAY, C.G., PROSSER, J., PHILIPS, M.F., and KLAGSBRUN, M. (1988). Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds. Brain Res. 460, 253-259.
14. GALLYAS, F., ZOLTAY, G., and BALAS, I. (1992). An immediate light microscopic response of neuronal somata, dendrites and axons to contusing concussive head injury in the rat. Acta Neuropathol. 83, 394-401.
15. GIULIAN, D., WOODWARD, J., YOUNG, D.G., KREBS, J.F., and LACHMAN, L.B. (1988). Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization. J. Neurosci. 8, 2485-2490.
16. GIULIAN, D., and LACHMAN, L.B. (1985). Interleukin-1 stimulation of astroglial proliferation after brain injury. Science 228, 497-499.
17. GRIFFIN, W.S.T., STANLEY, L.C., LING, C., WHITE, L., MACLEOD, V., PERROT, L.J., WHITE, C.L., III, and ARAOZ, C. (1989). Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. P.N.A.S. USA 86, 7611-7615.
18. HATTEN, M.E., LIEM, R.K.H., SHELANSKI, M.L., and MASON, C.A. (1991). Astroglia in CNS injury. Glia 4, 233-243.
19. HILL, S.J., BARBARESE, E., and MCINTOSH, T.K. (1996). Regional heterogeneity in the response of astrocytes following traumatic brain injury in the adult rat. J. Neuropathol. Exptl. Neurol. 55, 1221-1229.
20. HINKLE, D.A., HARNEY, J.P., CAI, A., HILT, D.C., YAROWSKY, P.J., and WISE, P.M. (1997). FGF-2 and IL-1β regulate S100β expression in cultured astrocytes. Neuroscience (in press).
21. IWAMOTO, Y., YAMAKI, T., MURAKAMI, N., SUGAWA, N., YOSHINO, E., UEDA, S., NOSAKA, K., NISHINO, H., and IWASHIMA, A. (1994). Basic fibroblast growth factor messenger RNA is expressed strongly at the acute stage of cerebral contusion. Life Sci. 55, 1651-1656.
22. KINDY, M.S., BHAT, A.N., and BHAT, N.R. (1992). Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum, and hippocampus. Mol. Brain Res. 13, 199-206.
23. KLIGMAN, D., and HILT, D.C. (1988). The S100 protein family. Trends Biochem. Sci. 13, 437-442.
24. KLIGMAN, D., and MARSHAK, D.R. (1985). Purification and characterization of a neurite extension factor from bovine brain. P.N.A.S. (USA) 82, 7136-7139.
25. LIGHTHALL, J.W. (1988). Controlled cortical impact: a new experimental brain injury model. J. Neurotrauma 5, 1-15.
26. MALHOTRA, S., SHINTKA, T., and ALBRINK, I. (1990). Reactive astrocytes - a review. Cryobios 61, 133-160.
27. MIYAKE, T., HATTORI, T., FUKUDA, M., KITAMURA, T., and FUJITA, S. (1988). Quantitative studies on proliferative changes of reactive astrocytes in mouse cerebral cortex. Brain Res. 451, 133-138.
28. NEARY, J.T., BAKER, L., JORGENSEN, S.L., and NORENBERG, M.D. (1994). Extracellular ATP induces stellation and increases glial fibrillary acidic protein content and DNA synthesis in primary astrocyte cultures. Acta Neuropathol. 87, 8-13.
29. NORENBERG, M.D. (1994). Astrocyte responses to CNS injury. J. Neuropathol. Exptl. Neurol. 53, 213-220.
30. PAXINOS, G., and WATSON, C. (1986). The Rat Brain in Stereotaxic Coordinates. New York: Academic Press.
31. PETITO, C., MORGELLO, S., FELIX, J., and LESSER, M. (1990). The two patterns of reactive astrocytosis in postischemic rat brain. J. Cereb. Blood Flow Metabol. 10, 850-859.
32. SCHIFFER, D., GIORDANA, M., CAVALLA, P., VIGLIANI, M., and ATTANASIO, A. (1997). Immunohistochemistry of glial reaction after injury in the rat: Double stainings and markers of cell proliferation. Intern. J. Develop. Neurosci. 11, 269-280.
33. SELINFREUND, R.H., BARGER, S.W., WELSH, M.J., and VAN ELDIK, L.J. (1990). Antisense inhibition of glial S100beta production results in alterations in cell morphology, cytoskeletal organization, and cell proliferation. J. Cell Biol. 111, 2021-2028.
34. STEWARD, O., TORRE, E.R., PHILLIPS, L.L., and TRIMMER, P.A. (1997). The process of reinnervation of the dentate gyrus of adult rats: Time course of increase in mRNA for glial fibrillary acidic protein. J. Neurosci. 10, 2373-2384.
35. STICHEL, C., and MULLER, H. (1994). Extensive and long-lasting changes in glial cells following transection of the post-commissural fornix in adult rat. Glia 10, 89-100.
36. TAUPIN, V., TOULMOND, S., SERRANO, A., BENAVIDES, I., and ZAVALA, F. (1993). Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. J. Neuroimmunol. 42, 177-186.
37. TODA, M., MIURA, M., ASOU, H., TOYA, S., and UYEMURA, K. (1994). Cell growth suppression of astrocytoma C6 cells by glial fibrillary acidic protein cDNA transfection. J. Neurochem. 63, 1975-1978.
38. WINNINGHAM-MAJOR, F., STAECKER, J.L., BARGER, S.W., COATS, S., and VAN ELDIK, L.J. (1989). Neurite extension and neuronal survival activities of recombinant S100beta proteins that differ in the content and position of cysteine residues. J. Cell Biol. 109, 3063-3071.
39. ZIMMER, D.B., and VAN ELDIK, L.J. (1989). Analysis of the calcium-modulated proteins, S100 and calmodulin, and their target proteins during C6 glioma cell differentiation. J. Cell Biol. 108, 141-151.