Regional heterogeneity in the response of astrocytes following traumatic brain injury in the adult rat

Journal of Neuropathology and Experimental Neurology

Volumn 55, Issue 12, 1996, Pages 1221-1229

  Hill, Sandra J ^a   Barbarese, Elisa ^a   McIntosh, Tracy K ^b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Blood brain barrier; Cajal's gold sublimate; Fluid percussion; Glial fibrillary acidic protein; S100 Protein; Vimentin

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEIN S 100; VIMENTIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN INJURY; CELL LOSS; CONTROLLED STUDY; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THALAMUS; WHITE MATTER;

EID: 0029857871     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199612000-00005     Document Type: Article

References (40)

1. Kimelberg HK, Norenberg MD. Astroglial responses to CNS trauma. In: Salzman SK, Faden AI, eds. The neurobiology of central nervous system trauma. New York: Oxford University Press, 1994: 193-208
2. Mathewson AJ, Berry M. Observations on the astrocyte response to a cerebral stab wound in adult rats. Brain Res 1985;327:61-69
3. Schiffer D, Giordana MT, Migheli A, Giaccone G, Pezzotta S, Mauro A. Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain. Brain Res 1986;374:110-18
4. Calvo JL, Carbonell AL, Boya J. Co-expression of vimentin and glial fibrillary acidic protein in astrocytes of the adult optic nerve. Brain Res 1990;532:355-57
5. Bignami A, Eng LF, Dahl D, Uyeda CT. Localization of the glial fibrillary acidic protein in astrocytes by imunofluorescence. Brain Res 1972;43:429-35
6. Bignami A, Dahl D. Astrocyte-specific protein and neuroglial differentiation. An immunofluorescence study with antibodies to the glial fibrillary acidic protein. J Comp Neurol 1974;153:27-38
7. Eng LF. Glial fibrillary acidic protein (GFAP): The major protein of glial intermediate filaments in differentiated astrocytes. J Neuroimmunol 1985;8:203-14
8. Takamiya Y, Koshsaka S, Toya S, Otani M, Tsukada Y. Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats. Dev Brain Res 1988;38:201-10
9. Calvo JL, Carbonell AL, Boya J. Co-expression of glial fibrillary acidic protein and vimentin in reactive astrocytes following brain injury in rats. Brain Res 1991;566:333-36
10. Ciesielski-Treska J, Goetschy JF, Ulrich G, Aunis D. Acquisition of vimentin in astrocytes cultured from postnatal rat brain. J Neurocytol 1988;17:79-88
11. Schnitzer J, Franke WW, Schachner M. Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system. J Cell Biol 1981;90:435-47
12. Pixley SKR, De Vellis J. Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin. Dev Brain Res 1984;15:201-9
13. Griffin WST, Stanley LC, Ling C, et al. Brain interleukin and S100 immunoreactivity are elevated in Down syndrome and Alzheimers. Proc Natl Acad Sci 1989;86:7611-15
14. Baudier J, Cole RD. Interactions between the microtubule-associated proteins and S100b regulate phosphorylation by the calcium/calmodulin-dependent protein kinase II. J Biol Chem 1988;263:5876-83
15. Bianchi R, Giambanco I, Donato R. S100 protein, but not calmodulin, binds to the glial fibrillary acidic protein and inhibits its polymerization in a calcium dependent manner. J Biol Chem 1993;268: 12669-74
16. Kligman D, Patel J. A protein modulator stimulates C kinase-dependent phosphorylation of a 90K substrate in synaptic membranes. J Neurochem 1986;47:298-303
17. Shashoua VE, Hesse GW, Moore BW. Proteins of the brain extracellular fluid: Evidence for release of S-100 protein. J Neurochem 1984;42:1536-41
18. Van Eldik LJ, Zimmer DB. Secretion of S100 from rat C6 glioma cells. Brain Res 1987;436:367-70
19. Barger SW, Van Eldik LJ. S100B stimulates calcium fluxes in glial and neuronal cells. J Biol Chem 1992;267:9689-94
20. McIntosh TK, Vink R, Noble L, Yamakami I, Fernyak S, Soares H, Faden AL. Traumatic brain injury in the rat: Characterization of a lateral fluid-percussion model. Neuroscience 1989;28:233-44
21. Gennarelli TA. Animal models of human head injury. J Neurotrauma 1994;11:357-68
22. Polvishock JT, Hayes RL, Michel ME, McIntosh TK. Workshop on animal models of traumatic brain injury. J Neurotrauma 1994;11: 723-32
23. Cortez SC, McIntosh TK, Noble LJ. Experimental fluid percussion brain injury: Vascular disruption and neuronal and glial alterations. Brain Res 1989;482:271-82
24. Soares HD, Thomas M, Cloherty K, McIntosh TK. Development of prolonged focal cerebral edema and regional cation changes following experimental brain injury in the rat. J Neurochem 1992;58: 1845-52
25. Tanno H, Nockels RP, Pitts LH, Noble LJ. Breakdown of the blood-brain barrier after fluid percussive brain injury in the rat. Part 1: Distribution and time course of protein extravasation. J Neurotrauma 1992;9:21-32
26. Dietrich WD, Alonso O, Halley M. Early microvascular and neuronal consequences of traumatic brain injury: A light and electron microscopic study in rats. J Neurotrauma 1994;11:289-92
27. Soares HD, Hicks RR, Smith DH, McIntosh TK. Inflammatory leukocyte recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. J Neurosci 1996. Forthcoming.
28. Guilian D, Woodward J, Young DG, Krebs JF, Lachman LB. Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization. J Neurosci 1988;8:2485-90
29. Guilian D, Chen J, Injeman JE, Geroge JK, Noponen M. The role of mononuclear phagocytes in wound healing after traumatic injury to the mammalian brain. J Neurosci 1989;9:4416-29
30. Vaughn JE, Pease DC. Electron microscopy of classically stained astrocytes. J Comp Neurol 1969;131:143-54
31. Thompson SW. Selected histochemical and histopathological methods. Springfield, IL: Charles C. Thomas, 1966:814-16
32. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci 1979;76:4350-54
33. Smith DH, Okiyama K, Thomas MJ, Claussen B, McIntosh TK. Evaluation of memory dysfunction following experimental brain injury using the morris water maze. J Neurotrauma 1991;8:259-69
34. Lowenstein DH, Thomas MJ, Smith DH, McIntosh TK. Selective vulnerability of dentate hilar neurons following traumatic brain injury: A potential mechanistic link between head trauma and disorders of the hippocampus. J Neurosci 1992;12:4846-53
35. Hicks RR, Smith DH, McIntosh TK. Temporal responses and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats. Brain Res Forthcoming.
36. Hatten ME. Neuronal regulation of astroglial morphology and proliferation in vitro. J Cell Biol 1985;100:384-96
37. Guilian D, Lachman LB. Interleukin-1 stimulation of astroglial proliferation after brain injury. Science 1985;228:497-99
38. Woodroofe MN, Sarna GS, Wadhwa M, Hayes GM, Loughlin AJ, Tinker A, Cuzner ML. Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: Evidence of a role for microglia in cytokine production. J Neuroimmuno 1991;33:227-36
39. Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces expression of interleukin-1B mRNA in the rat brain. Molecular Brain Research 1995;30:125-30
40. Taupin V, Toulmond S, Serrano A, Bernavides J, Zavala F. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand. J Neuroimmuno 1993;42:177-85