Effects of the dopamine D3 antagonist PD 58491 and its interaction with the dopamine D3 agonist PD 128907 on brain dopamine synthesis in rat

Journal of Neurochemistry

Volumn 69, Issue 6, 1997, Pages 2363-2368

  Whetzel, S Z ^a   Shih, Y H ^a   Georgic, L M ^a   Akunne, H C ^a   Pugsley, T A ^a  

^a PFIZER INC   (United States)

Author keywords

Dopamine D3 receptors; Dopamine synthesis; PD 128907; PD 58491; Rat brain

Indexed keywords

3,4,4A,10B TETRAHYDRO 4 PROPYL 2H,5H [1]BENZOPYRANO[4,3 B][1,4]OXAZIN 9 OL; DOPA; DOPAMINE 3 RECEPTOR BLOCKING AGENT; GAMMA BUTYROLACTONE; PD 58491; UNCLASSIFIED DRUG; 3,4,4A,10B TETRAHYDRO 4 PROPYL 2H,5H (1)BENZOPYRANO(4,3 B) 1,4 OXAZIN 9 OL; 3,4,4A,10B-TETRAHYDRO-4-PROPYL-2H,5H-(1)BENZOPYRANO(4,3-B)-1,4-OXAZIN-9-OL; 5 HYDROXYTRYPTOPHAN; BENZIMIDAZOLE DERIVATIVE; BENZOPYRAN DERIVATIVE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; DRD3 PROTEIN, HUMAN; DRD3 PROTEIN, RAT; OXAZINE DERIVATIVE; QUINPIROLE; THYMIDINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CHO CELL; DOPAMINE BRAIN LEVEL; DOPAMINE METABOLISM; ENZYME ACTIVITY; HYPOTHESIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; ANIMAL; BIOSYNTHESIS; BRAIN; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; DRUG POTENTIATION; HAMSTER; HUMAN; METABOLISM; RAT STRAIN;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

5-HYDROXYTRYPTOPHAN; ANIMALS; BENZIMIDAZOLES; BENZOPYRANS; BRAIN; CHO CELLS; CRICETINAE; DIHYDROXYPHENYLALANINE; DOPAMINE; DOPAMINE AGONISTS; DRUG INTERACTIONS; HUMANS; MALE; OXAZINES; QUINPIROLE; RATS; RATS, INBRED STRAINS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; THYMIDINE;

EID: 0030613813     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69062363.x     Document Type: Article

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