-
1
-
-
0028085078
-
The insulin signaling system
-
White, M. F. & Kahn, C. R. (1994) The insulin signaling system, J. Biol. Chem. 269, 1-4.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1-4
-
-
White, M.F.1
Kahn, C.R.2
-
2
-
-
0025813375
-
The structure of the insulin-receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun, X. J., Rothenberg, P., Kahn, C. R., Backer, J. M., Araki, E., Wilden, P. A., Cahill, D. A., Goldstein, B. J. & White, M. F. (1991) The structure of the insulin-receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352, 73-77.
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
3
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signalling
-
Sun, X. J., Wang, L. M., Zhang, Y. T., Yenush, L., Myers, M. G. Jr. Glasheen, E., Lane, W. S., Pierce, J. H. & White, M. F. (1995) Role of IRS-2 in insulin and cytokine signalling. Nature 377, 173-177.
-
(1995)
Nature
, vol.377
, pp. 173-177
-
-
Sun, X.J.1
Wang, L.M.2
Zhang, Y.T.3
Yenush, L.4
Myers Jr., M.G.5
Glasheen, E.6
Lane, W.S.7
Pierce, J.H.8
White, M.F.9
-
4
-
-
0026777369
-
A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction
-
Pelicci, G., Lanfrancone, L., Grigani, F. McGlade, J., Cavallo, F., Forni, G., Nicoletti, I., Pawson, T. & Pelicci, P. G. (1992) A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction, Cell 70, 93-104.
-
(1992)
Cell
, vol.70
, pp. 93-104
-
-
Pelicci, G.1
Lanfrancone, L.2
Grigani, F.3
McGlade, J.4
Cavallo, F.5
Forni, G.6
Nicoletti, I.7
Pawson, T.8
Pelicci, P.G.9
-
5
-
-
0026594654
-
YMXM motifs of IRS-1 define the substrate specificity of the insulin receptor kinase
-
Shoelson, S. E., Chatterjee, S., Chaudhuri, M. & White, M. F. (1992) YMXM motifs of IRS-1 define the substrate specificity of the insulin receptor kinase, Proc. Natl Acad. Sci. USA 89, 2027-2031.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 2027-2031
-
-
Shoelson, S.E.1
Chatterjee, S.2
Chaudhuri, M.3
White, M.F.4
-
6
-
-
0028568639
-
A region in She distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors
-
Blaikie, P., Immanuel, D., Wu, J., Li, N., Yajnik, V. & Margolis, B. (1994) A region in She distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors, J. Biol. Chem. 269, 32031-32034.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32031-32034
-
-
Blaikie, P.1
Immanuel, D.2
Wu, J.3
Li, N.4
Yajnik, V.5
Margolis, B.6
-
7
-
-
0029067403
-
PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine
-
Kavanaugh, W. M., Turck, C. W. & Williams, L. T. (1995) PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine. Science 268, 1177- 1179.
-
(1995)
Science
, vol.268
, pp. 1177-1179
-
-
Kavanaugh, W.M.1
Turck, C.W.2
Williams, L.T.3
-
8
-
-
0028912999
-
Phosphotyrosine-dependent interaction of SHC and insulin-receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain
-
Gustafson, T. A., He, W., Craparo, A., Schaub, C. D. & O'Neill, T. J. (1995) Phosphotyrosine-dependent interaction of SHC and insulin-receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain, Mol. Cell. Biol. 15, 2500-2508.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2500-2508
-
-
Gustafson, T.A.1
He, W.2
Craparo, A.3
Schaub, C.D.4
O'Neill, T.J.5
-
9
-
-
0029040133
-
The phosphotyrosine interaction domain of She binds an LXNPXY motif on the epidermal growth factor receptor
-
Batzer, A. G., Blaikie, P., Nelson, K., Schlessinger, J. & Margolis, B. (1995) The phosphotyrosine interaction domain of She binds an LXNPXY motif on the epidermal growth factor receptor. Mol. Cell. Biol. 15, 4403-4409.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4403-4409
-
-
Batzer, A.G.1
Blaikie, P.2
Nelson, K.3
Schlessinger, J.4
Margolis, B.5
-
10
-
-
0029939448
-
PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface
-
Lemmon, M. A., Ferguson, K. M. & Schlessinger, J. (1996) PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface, Cell 85, 621-624.
-
(1996)
Cell
, vol.85
, pp. 621-624
-
-
Lemmon, M.A.1
Ferguson, K.M.2
Schlessinger, J.3
-
11
-
-
0029020217
-
The pleckstrin homology domain in insulin-receptor substrate-1 sensitizes insulin signaling
-
Myers, M. G. Jr, Grammer, T. C., Brooks, J., Glasheen, E. M., Wang, L.-M., Sun, X. J., Blenis, J., Pierce, J. H. & White, M. F. (1995) The pleckstrin homology domain in insulin-receptor substrate-1 sensitizes insulin signaling, J. Biol. Chem. 270, 11715-11718.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11715-11718
-
-
Myers Jr., M.G.1
Grammer, T.C.2
Brooks, J.3
Glasheen, E.M.4
Wang, L.-M.5
Sun, X.J.6
Blenis, J.7
Pierce, J.H.8
White, M.F.9
-
12
-
-
0029029892
-
Tyrosine phosphorylation of insulin-receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region
-
Voliovitch, H., Schindler, D. G., Hadari, Y. R., Taylor, S. I., Accili, D. & Zick, Y. (1995) Tyrosine phosphorylation of insulin-receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region, J. Biol. Chem. 270, 18083-18087.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18083-18087
-
-
Voliovitch, H.1
Schindler, D.G.2
Hadari, Y.R.3
Taylor, S.I.4
Accili, D.5
Zick, Y.6
-
13
-
-
0029820085
-
The pleckstrin homology domain is the principle link between insulin receptor and IRS-1
-
Yenush, L., Makati, K. J., Smith-Hall, J., Ishibashi, O., Myers, M. G. Jr & White, M. F. (1996) The pleckstrin homology domain is the principle link between insulin receptor and IRS-1, J. Biol. Chem. 271, 24300-24306.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24300-24306
-
-
Yenush, L.1
Makati, K.J.2
Smith-Hall, J.3
Ishibashi, O.4
Myers Jr., M.G.5
White, M.F.6
-
14
-
-
0026595373
-
The expression and function of IRS-1 in insulin signal transmission
-
Sun, X. J., Miralpeix, M., Myers, M. G. Jr. Glasheen, E. M., Backer, J. M., Kahn, C. R. & White, M. F. (1992) The expression and function of IRS-1 in insulin signal transmission, J. Biol. Chem. 267, 22662-22672.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22662-22672
-
-
Sun, X.J.1
Miralpeix, M.2
Myers Jr., M.G.3
Glasheen, E.M.4
Backer, J.M.5
Kahn, C.R.6
White, M.F.7
-
15
-
-
0027416751
-
Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3′-kinase. Formation of binary and ternary signaling complexes in intact cells
-
Backer, J. M., Myers, M. G. Jr, Sun, X.-J., Chin, D. J., Shoelson, S. E., Miralpeix, M. & White, M. F. (1993) Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3′-kinase. Formation of binary and ternary signaling complexes in intact cells, J. Biol. Chem. 268, 8204-8212.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8204-8212
-
-
Backer, J.M.1
Myers Jr., M.G.2
Sun, X.-J.3
Chin, D.J.4
Shoelson, S.E.5
Miralpeix, M.6
White, M.F.7
-
16
-
-
0028969974
-
Recombinant human insulin-receptor substrate-1 protein. Tyrosine phosphorylation and in vitro binding of insulin receptor kinase
-
Siemeister, G., Al-Hasani, H., Klein, H. W., Kellner, S., Streicher, R., Krone, W. & Müller-Wieland, D. (1995) Recombinant human insulin-receptor substrate-1 protein. Tyrosine phosphorylation and in vitro binding of insulin receptor kinase, J. Biol. Chem. 270, 4870-4874.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4870-4874
-
-
Siemeister, G.1
Al-Hasani, H.2
Klein, H.W.3
Kellner, S.4
Streicher, R.5
Krone, W.6
Müller-Wieland, D.7
-
17
-
-
0029866195
-
Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786
-
Sawka-Verhelle, D., Tartare-Deckert, S., White, M. F. & Van Obberghen, E. (1996) Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786, J. Biol. Chem. 271, 5980-5983.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5980-5983
-
-
Sawka-Verhelle, D.1
Tartare-Deckert, S.2
White, M.F.3
Van Obberghen, E.4
-
18
-
-
0026730995
-
The insulin receptor juxtamembrane region contains two independent tyrosine/β-turn internalization signals
-
Backer, J. M., Shoelson, S. E., Weiss, M. A., Hua, Q. X., Cheatham, R. B., Haring, E., Cahill, D. C. & White, M. F. (1992) The insulin receptor juxtamembrane region contains two independent tyrosine/β-turn internalization signals, J. Cell Biol. 118, 831-839.
-
(1992)
J. Cell Biol.
, vol.118
, pp. 831-839
-
-
Backer, J.M.1
Shoelson, S.E.2
Weiss, M.A.3
Hua, Q.X.4
Cheatham, R.B.5
Haring, E.6
Cahill, D.C.7
White, M.F.8
-
19
-
-
0029157595
-
Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif
-
Chen, D., Van Horn, D. J., White, M. F. & Backer, J. M. (1995) Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif, Mol. Cell. Biol. 15, 4711-4717.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4711-4717
-
-
Chen, D.1
Van Horn, D.J.2
White, M.F.3
Backer, J.M.4
-
20
-
-
0026660653
-
The phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation
-
Backer, J. M., Myers, M. G. Jr, Shoelson, S. E., Chin, D. J., Sun, X. J., Miralpeix, M., Hu, P., Margolis, B., Skolnik, E. Y., Schlessinger, J. & White, M. F. (1992) The phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation, EMBO J. 11, 3469-3479.
-
(1992)
EMBO J.
, vol.11
, pp. 3469-3479
-
-
Backer, J.M.1
Myers Jr., M.G.2
Shoelson, S.E.3
Chin, D.J.4
Sun, X.J.5
Miralpeix, M.6
Hu, P.7
Margolis, B.8
Skolnik, E.Y.9
Schlessinger, J.10
White, M.F.11
-
21
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
22
-
-
0022558555
-
Purification, reconstitution, and characterization of the lac permease of Escherichia coli
-
Viitanen, P., Newman, M. J., Foster, D. L., Wilson, T. H. & Kaback, H. R. (1986) Purification, reconstitution, and characterization of the lac permease of Escherichia coli, Methods Enzymol. 125, 429-452.
-
(1986)
Methods Enzymol.
, vol.125
, pp. 429-452
-
-
Viitanen, P.1
Newman, M.J.2
Foster, D.L.3
Wilson, T.H.4
Kaback, H.R.5
-
23
-
-
0023814924
-
Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity
-
White, M. F., Livingston, J. N., Backer, J. M., Lauris, V. Dull, T. J., Ullrich, A. & Kahn, C. R. (1988) Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity, Cell 54, 641-649.
-
(1988)
Cell
, vol.54
, pp. 641-649
-
-
White, M.F.1
Livingston, J.N.2
Backer, J.M.3
Lauris, V.4
Dull, T.J.5
Ullrich, A.6
Kahn, C.R.7
-
24
-
-
13344278677
-
Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo
-
Isukoff, S. J., Yu, Y. P., Su, Y. C., Blaikie, P., Yajnik, V., Rose, E., Weidner, K. M., Sachs, M., Margolis, B. & Skolnik, E. Y. (1996) Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo, J. Biol. Chem. 271, 3959-3962.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3959-3962
-
-
Isukoff, S.J.1
Yu, Y.P.2
Su, Y.C.3
Blaikie, P.4
Yajnik, V.5
Rose, E.6
Weidner, K.M.7
Sachs, M.8
Margolis, B.9
Skolnik, E.Y.10
-
25
-
-
0029121174
-
The role of the NPXY motif in the insulin receptor in tyrosine phosphorylation of insulin-receptor substrate-1 and Shc
-
Kaburagi, Y. Yamamoto-Honda, R., Tobe, K., Ueki, K., Yachi, M., Akanuma, Y., Stephens, R. M., Kaplan, D., Yazaki, Y. & Kadowaki, T. (1995) The role of the NPXY motif in the insulin receptor in tyrosine phosphorylation of insulin-receptor substrate-1 and Shc, Endocrinology 136, 3437-3443.
-
(1995)
Endocrinology
, vol.136
, pp. 3437-3443
-
-
Kaburagi, Y.1
Yamamoto-Honda, R.2
Tobe, K.3
Ueki, K.4
Yachi, M.5
Akanuma, Y.6
Stephens, R.M.7
Kaplan, D.8
Yazaki, Y.9
Kadowaki, T.10
-
26
-
-
0028219966
-
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth
-
Keegan, A. D., Nelms, K., White, M., Wang, L.-M., Pierce, J. H. & Paul, W. E. (1994) An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth, Cell 76, 811-820.
-
(1994)
Cell
, vol.76
, pp. 811-820
-
-
Keegan, A.D.1
Nelms, K.2
White, M.3
Wang, L.-M.4
Pierce, J.H.5
Paul, W.E.6
-
27
-
-
0030032062
-
Identification of residues that control specific binding of the She phosphotyrosine-binding domain to phosphotyrosine sites
-
van der Geer, P., Wiley, S., Gish, G. D., Lai, V. K. M., Stephens, R., White, M. F. Kaplan, D. & Pawson, T. (1996) Identification of residues that control specific binding of the She phosphotyrosine-binding domain to phosphotyrosine sites, Proc. Natl Acad. Sci. USA 93, 963-968.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 963-968
-
-
Van Der Geer, P.1
Wiley, S.2
Gish, G.D.3
Lai, V.K.M.4
Stephens, R.5
White, M.F.6
Kaplan, D.7
Pawson, T.8
-
28
-
-
0029010308
-
The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif
-
Songyang, Z., Margolis, B., Chaudhuri, M., Shoelson, S. E. & Cantley, L. C. (1995) The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif, J. Biol. Chem. 270, 14863-14866.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14863-14866
-
-
Songyang, Z.1
Margolis, B.2
Chaudhuri, M.3
Shoelson, S.E.4
Cantley, L.C.5
-
29
-
-
0029918526
-
Thermodynamic studies of SHC phosphotyrosine interaction domain recognition of the NPXpY motif
-
Mandiyan, V., O'Brien, R., Zhou, M., Margolis, B., Lemmon, M. A., Sturtevant, J. M. & Schlessinger, J. (1996) Thermodynamic studies of SHC phosphotyrosine interaction domain recognition of the NPXpY motif, J. Biol. Chem. 271, 4770-4775.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4770-4775
-
-
Mandiyan, V.1
O'Brien, R.2
Zhou, M.3
Margolis, B.4
Lemmon, M.A.5
Sturtevant, J.M.6
Schlessinger, J.7
-
30
-
-
0030010590
-
Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
-
Eck, M. J., Dhe-Paganon, S., Trüb, T., Nolte, R. T. & Shoelson, S. E. (1996) Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor, Cell 85, 695-705.
-
(1996)
Cell
, vol.85
, pp. 695-705
-
-
Eck, M.J.1
Dhe-Paganon, S.2
Trüb, T.3
Nolte, R.T.4
Shoelson, S.E.5
|