Regulation of [3H]norepinephrine release from guinea pig hippocampus by σ2 receptors

European Journal of Pharmacology

Volumn 326, Issue 2-3, 1997, Pages 133-138

  Weatherspoon, John K ^a   Gonzalez Alvear, Grace M ^a   Werling, Linda L ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

BIMU 8 (+) Pentazocine; Hippocampus; Norepinephrine; 2 Receptor

Indexed keywords

1 CYCLOPROPYLMETHYL 4 [2 (4 FLUOROPHENYL) 2 OXOETHYL]PIPERIDINE; 2,3 DIHYDRO 3 ISOPROPYL 2 OXO 1 BENZIMIDAZOLECARBOXYLIC ACID 3ALPHA TROPANYLAMIDE; N METHYL DEXTRO ASPARTIC ACID; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)CYCLOHEXYLAMINE; PENTAZOCINE; RECEPTOR SUBTYPE; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG; (ENDO N 8 METHYL 8 AZABICYCLO (3.2.1)OCT 3 YL) 2,3 DIHYDRO 3 ISOPROPYL 2 OXO 1H BENZIMIDAZOL 1 CARBOXAMIDE; (ENDO-N-8-METHYL-8-AZABICYCLO-(3.2.1)OCT-3-YL)-2,3-DIHYDRO-3-ISOPROPYL-2-OXO-1H-BENZIMIDAZOL-1-CARBOXAMIDE; BENZIMIDAZOLE DERIVATIVE; DIAGNOSTIC AGENT; FUSED HETEROCYCLIC RINGS; NORADRENALIN; TRITIUM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GUINEA PIG; HIPPOCAMPUS; IN VITRO STUDY; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; ANIMAL; DRUG ANTAGONISM; DRUG SCREENING; METABOLISM; PHYSIOLOGY; RADIOASSAY;

ANIMALS; BENZIMIDAZOLES; BICYCLO COMPOUNDS, HETEROCYCLIC; DRUG EVALUATION, PRECLINICAL; GUINEA PIGS; HIPPOCAMPUS; MALE; NOREPINEPHRINE; PENTAZOCINE; RADIOLIGAND ASSAY; RECEPTORS, SIGMA; TRITIUM;

EID: 0030611056     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)85407-6     Document Type: Article

References (26)

1. Bergeron R., De Montigny C., Debonnel G. Biphasic effects of sigma ligands on the neuronal response to N-methyl-D-aspartate. Naunyn-Schmiedeberg's Arch. Pharmacol. 351:1995;252.
2. 3 receptor ligand in NG-108 cells, selectively labels σ-2 binding sites in guinea pig hippocampus. J. Pharmacol. Exp. Ther. 267:1993;961.
3. Bowen W.D., Kirschner B.N., Newman A.H., Rice K.C. σ Receptors negatively modulate agonist-stimulated phosphoinositide metabolism in rat brain. Eur. J. Pharmacol. 149:1988;399.
4. Bowen W.D., Walker J.M., DeCosta B.R., Wu R., Tolentino P.J., Finn D., Rothman R.B., Rice K.C. Characterization of the enantiomers of cis-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)cyclohexylamine (BD737 and BD738): novel compounds with high affinity, selectivity, and biological efficacy at σ receptors. J. Pharmacol. Exp. Ther. 262:1992;32.
5. 2 receptor. Mol. Pharmacol. 42:1992;471.
6. 3H]DuP 734 [1-(cyclopropylmethyl)-4-(2′(4″-fluorophenyl)-2′-oxoethyl) piperidine HBr]: a receptor binding profile of a high-affinity σ receptor ligand in guinea pig brain. J. Pharmacol. Exp. Ther. 263:1992;1175.
7. 3H]dopamine release from rat striatal slices by σ receptor ligands. J. Pharmacol. Exp. Ther. 271:1994;212.
8. Gonzalez-Alvear G.M., Werling L.L. Sigma receptor regulation of norepinephrine release from rat hippocampal slices. Brain Res. 673:1995;61.
9. Gonzalez-Alvear G.M., Thompson-Montgomery D., Deben S.E., Werling L.L. Functional and binding properties of σ receptors in rat cerebellum. J. Neurochem. 65:1995;2509.
10. Gudelsky G.A. Effects of σ receptor ligands on the extracellular concentration of dopamine in the striatum and prefrontal cortex of the rat. Eur. J. Pharmacol. 286:1995;223.
11. 3H-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine. J. Neurosci. 6:1986;1757.
12. Hellewell S.B., Bowen W.D. A σ-like binding site in rat PC12 cells: decreased affinity for (+)benzomorphans and lower M.W. suggest a different σ receptor from that of guinea pig brain. Brain Res. 527:1990;244.
13. 3H]acetylcholine release from rat hippocampal slices. Eur. J. Pharmacol. 200:1991;343.
14. Martin W.R., Eades C.G., Thompson J.A., Huppler R.E., Gilbert R.E., Gilbert P.E. The effects of morphine- and nalorphine-like drugs in the non-dependent and morphine-dependent chronic spinal dog. J. Pharmacol. Exp. Ther. 197:1976;517.
15. Mash D., Zabetian C.P. Sigma receptors are associated with cortical limbic areas in the primate brain. Synapse. 12:1992;195.
16. McLean S., Weber E. Autoradiographic visualization of haloperidol-sensitive σ receptors in guinea pig brain. Neuroscience. 25:1988;259.
17. Monnet F.P., Debonnel G., De Montigny C. In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands. J. Pharmacol. Exp. Ther. 261:1992;123.
18. 3H]-noradrenaline release in rat hippocampal slices. Br. J. Pharmacol. 119:1996;65.
19. Quirion R., Bowen W.D., Itzhak Y., Junien J.L., Musacchio J.M., Rothman R.B., Su T.-P., Tam S.W., Taylor D.P. A proposal for the classification of σ sites. Trends Pharmacol. Sci. 13:1992;85.
20. Rothman, R.B., Mahboubi, A., Reid, A.A., De Costa, B.R., Jacobson, A.E., Rice, K.C., 1990. Interaction of calcium channel blockers with multiple σ binding sites in guinea pig brain. In: Harris, L.S. (Ed.), Proceedings of the Committee on Drug Dependence. NIDA Monograph Series, Rockville, MD, p. 322.
21. 3H]1,3-di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by σ ligands. Mol. Pharmacol. 39:1991;222.
22. 2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles. J. Pharmacol. Exp. Ther. 263:1992;1167.
23. Vaupel D.B. Naltrexone fails to antagonize the σ effects of PCP and SKF10,047 in the dog. Eur. J. Pharmacol. 92:1983;269.
24. Vilner B.J., John C.S., Bowen W.D. Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines. Cancer Res. 55:1995;408.
25. Walker J.M., Bowen W.D., Walker F.O., Matsumoto R.R., DeCosta B., Rice K.C. Sigma receptors: biology and function. Pharm. Rev. 42:1990;355.
26. 3H]dopamine release from mesolimbic and mesocortical areas of guinea pig brain by σ receptors. Schizophr. Res. 21:1996;51.