In vivo occupancy of D2 dopamine receptors by nafadotride

Neuropsychopharmacology

Volumn 17, Issue 2, 1997, Pages 67-71

  Levant, Beth ^a   Vansell, Nichole R ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

3H Spiperone; D2 dopamine receptor; EEDQ (N ethoxycarbonyl 2 ethoxy 1,2 dihydroquinoline); In vivo occupancy; Nafadotride; Striatum

Indexed keywords

2 ETHOXY 1(2H) QUINOLINECARBOXYLIC ACID ETHYL ESTER; BUTACLAMOL; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; HALOPERIDOL; NAFADOTRIDE; RADIOLIGAND; SPIPERONE; DOPAMINE RECEPTOR BLOCKING AGENT; NAPHTHALENE DERIVATIVE; PYRROLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN MEMBRANE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR OCCUPANCY; SUBCUTANEOUS DRUG ADMINISTRATION; ANIMAL; DOSE RESPONSE; DRUG EFFECT; SPRAGUE DAWLEY RAT;

ANIMALS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; NAPHTHALENES; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2;

EID: 0030610579     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(97)00024-9     Document Type: Article

References (11)

1. 2 receptor mRNA. Brain Res 564:203-219
2. Caine SB, Koob GF (1993): Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science 260:1814-1816
3. 3 receptor preferring ligands on the acquisition of place conditioning in rats. Behav Pharmacol 7:105-109
4. Daly SA, Waddington JL (1993): Behavioral effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other "D-2-like" agonists. Neuropharmacology 32:509-510
5. 3H]7-OH-DPAT-labeled binding sites in rat brain to inactivation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. Brain Res 698:146-154
6. Levant B (1996): Distribution of dopamine receptor subtypes in the CNS. In Stone TW (ed), CNS Neurotransmitters and Neuromodulators. Dopamine. Boca Raton, FL, CRC Press, pp 77-87
7. 3 receptors. Synapse 14:90-95
8. 3 dopamine receptors. Eur J Pharmacol 278:243-247
9. 2 dopamine receptors by 7-OH-DPAT. Synapse 24:60-64
10. 2 receptor occupation by typical and atypical antipsychotic drugs in vivo. J Pharmacol Exp Ther 265:498-508
11. 3-selective receptor ligand. Drug Dev Res 30:257-259