Carbachel-induced presser responses and muscarinic M1 receptors in the central nucleus of amygdala in conscious rats

European Journal of Pharmacology

Volumn 333, Issue 1, 1997, Pages 63-67

  Aslan, Neslihan ^a   Gören, Zafer ^a   Onat, Filiz ^a   Oktay, Şule ^a  

^a MARMARA UNIVERSITY   (Turkey)

Author keywords

Amygdala, central nucleus of; Blood pressure; Carbachol; Muscarinic M1 receptor; Rat

Indexed keywords

CARBACHOL; METHOCTRAMINE; MUSCARINIC M1 RECEPTOR; PIRENZEPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; DIAMINE; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HEART RATE; LATERAL BRAIN VENTRICLE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BLOOD PRESSURE; DOSE RESPONSE; DRUG EFFECT; FEMALE; HISTOLOGY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; SPRAGUE DAWLEY RAT;

AMYGDALA; ANIMALS; BLOOD PRESSURE; CARBACHOL; DIAMINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART RATE; INJECTIONS, INTRAVENTRICULAR; MALE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; PARASYMPATHOLYTICS; PIRENZEPINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC;

EID: 0030610271     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01106-0     Document Type: Article

References (45)

1. Ally A., Hara Y., Murayama S. Cardiovascular effects of central administration of cholinomimetics in anesthetized cats. Neuropharmacology. 32:1993;185-193.
2. Aslan N., Gören Z., Onat F., Oktay Ş. Muscarinic receptors involved in blood pressure changes induced by electrical stimulation of central amygdaloid nucleus. Br. J. Pharmacol. 114:1995;334P.
3. Aslan N., Gören Z., Özkutlu U., Onat F., Oktay Ş. Modulation of the pressor response elicited by carbachol and electrical stimulation of the amygdala by muscarinic antagonists in conscious rats. Br. J. Pharmacol. 120:1997;35-40.
4. Barnes J.C., Roberts F.F. Central effects of muscarinic agonists and antagonists on hippocampal theta rhythm and blood pressure in the anesthetized rat. Eur. J. Pharmacol. 195:1991;233-240.
5. Brezenoff H.E. Cardiovascular responses to intra-hypothalamic injection of carbachol and certain cholinesterase inhibitors. Neuropharmacology. 11:1972;637-644.
6. Brezenoff H.E., Giuliano R. Cardiovascular control by cholinergic mechanisms in the central nervous system. Ann. Rev. Pharmacol. Toxicol. 22:1982;341-381.
7. Brezenoff H.E., Jenden D.J. Modification of arterial blood pressure in rats following microinjection of drugs into the posterior hypothalamus. Int. J. Neuropharm. 8:1969;593-600.
8. Brezenoff H.E., Wirecki T.S. The pharmacological specificity of muscarinic receptors in the posterior hypothalamus of the rat. Life Sci. 9:1970;99-109.
9. Buccafusco J.J. The role of central cholinergic neurons in the regulation of blood pressure and in experimental hypertension. Pharmacol. Rev. 48:1996;179-211.
10. Buccafusco J.J., Brezenoff H.E. Pharmacological study of a cholinergic mechanism within the rat posterior hypothalamic nucleus which mediates a hypertensive response. Brain Res. 165:1979;295-310.
11. Criscione L., Reis D.J., Talman W.T. Cholinergic mechanisms in the nucleus tractus solitarii and cardiovascular regulation in the rat. Eur. J. Pharmacol. 88:1983;47-55.
12. Dampney R.A.L. Functional organization of central pathways regulating the cardiovascular system. Physiol. Rev. 74:1994;323-364.
13. Davis M., Rainnie D., Cassell M. Neurotransmission in the rat amygdala related to fear and anxiety. Trends Neurol. Sci. 17:1994;208-214.
14. De Luca L.A., Franci C.R., Saad W.A., Camargo L.A.A., Antunes-Rodrigues J. Natriuresis induced by cholinergic stimulation of locus coeruleus in the rat. Physiol. Behav. 47:1990;605-610.
15. De Wildt D.J., Porsius A.J. Central cardiovascular effects of physostigmine in the cat: Possible cholinergic aspects of blood pressure regulation. Arch. Int. Pharmacodyn. Ther. 253:1981;22-39.
16. Dirnhuber P., Cullumbine H. The effect of anticholinesterase agents on the rat's blood pressure. Br. J. Pharmacol. 10:1955;12-15.
17. Doods H.N., Wilim K.D., Boddeke W.G.M., Entzeroth M. Characterization of muscarinic receptors in guinea-pig uterus. Eur. J. Pharmacol. 250:1993;223-230.
18. Dörje F., Wess J., Lambrecht G., Tacke R., Mutschler E., Brann M.R. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J. Pharmacol. Exp. Ther. 256:1991;727-733.
19. Galeno T.M., Van Hoesen G.W., Maixner W., Johnson A.K., Brody M.J. Contribution of the amygdala to development of spontaneous hypertension. Brain Res. 246:1982;1-6.
20. Galeno T.M., Van Hoesen G.W., Brody M.J. Central nucleus of amygdala lesion attenuates exaggerated hemodynamic responses to noise stress in the spontaneously hypertensive rat. Brain Res. 291:1984;249-259.
21. Gelsema A.J., McKitrick D.J., Calaresu F.R. Cardiovascular responses to chemical and electrical stimulation of amygdala in rats. Am. J. Physiol. 253:1987;R712-R718.
22. Giraldo E., Micheletti R., Montagna E., Giachetti A., Vigano M.A., Ladinsky H., Melchiorre C. Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine. J. Pharmacol. Exp. Ther. 244:1988;1016-1020.
23. Giuliano R., Ruggiero D.A., Morrison S., Ernsberger P., Reiss D.J. Cholinergic regulation of arterial pressure by the C1 area of the rostral ventrolateral medulla. J. Neurosci. 9:1989;923-942.
24. Hammer R., Berrie C.P., Birdsal N.J.M., Burgen A.S.V., Hulme E.C. Pirenzepine distinguishes between different subclasses of muscarinic receptors. Nature. 283:1980;90-92.
25. Hara Y., Ally A., Murayama S. Central cardiovascular effects of physostigmine in anesthetized cats. Neuropharmacology. 31:1992;923-928.
26. Haruta K., Iguchi A., Matsubara T., Itoh K., Che-Lang C., Yoshida S., Terada R., Kanashiro M., Suzuki O., Nishimura H., Sakamoto N. Stimulation of muscarinic cholinoceptive neurons in the hippocampus evokes a pressor response with bradycardia. Life Sci. 50:1992;427-433.
27. Hoover D.B., Muth E.A., Jocobowitz D.M. Mapping of the distribution of acetylcholine, choline acetyltransferase and acetylcholinesterase in discrete areas of rat brain. Brain Res. 153:1978;295-306.
28. Krstic M.K., Djurkovic D. Cardiovascular responses to injection of cholinomimetic drugs into the cerebral ventricles of unanesthetized dogs. Br. J. Pharmacol. 17:1973;341-347.
29. Litchfield J.T., Wilcoxon F. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96:1949;99-116.
30. 3 receptor. Eur. J. Pharmacol. 215:1992;83-91.
31. Menani J.V., Saad W.A., Camargo L.A.A., Renzi A., De Luca L.A., Colombari E. The anteroventral third ventricle (AV3V) region is essential for pressor, dipsogenic and natriuretic responses to central carbachol. Neurosci. Lett. 113:1990;339-344.
32. Murugaian J., Sundaram K., Sapru H. Cholinergic mechanism in the ventrolateral medullary depressor area. Brain Res. 501:1989;355-363.
33. Nattie E.E., Li A. Ventral medulla sites of muscarinic receptor subtypes involved in cardiorespiratory control. J. Appl. Physiol. 69:1990;33-41.
34. Ohta H., Watanabe S., Ueki S. Cardiovascular changes induced by chemical stimulation of the amygdala in rats. Brain Res. Bull. 26:1991;575-581.
35. Oktay Ş., İlhan M., Onur R., Kayaalp S.O. Antagonism of the hypertensive effect of physostigmine in anesthetized rat by morphine. Arch. Int. Pharmacodyn. Ther. 271:1984;275-281.
36. Ozawa H., Uematsu T. Centrally mediated cardiovascular effects of intracisternal application of carbachol in anesthetized rats. Jpn. J. Pharmacol. 26:1976;339-346.
37. 2 cholinoceptors involved in cholinergic hypertension. Eur. J. Pharmacol. 250:1993;349-354.
38. Özkutlu U., Coşkun T., Onat F., Yeǧen B.Ç., Oktay Ş. Cardiovascular effects of centrally active cholinomimetics in conscious and anesthetized rats: The role of amygdala. Brain Res. Bull. 37:1995;569-573.
39. Paxinos, G., Watson, C., 1982. The Rat Brain in Stereotaxic Coordinates. Academic Press, San Diego.
40. 1 receptors. Eur. J. Pharmacol. 195:1991;139-143.
41. 3H ]propylbenzilycholine mustard and its distribution in the forebrain Brain Res. 1:1979;141-165.
42. Scheucher A., Alvarez A.L., Torres N., Dabsys S.M., FIinkielman S., Nahmod V.E., Pirola C.J. Cholinergic hyperactivity in the lateral septal area of spontaneously hypertensive rats: Depressor effect of hemicholinium-3 and pirenzepine. Neuropharmacology. 30:1991;391-397.
43. 2 muscarinic receptors mediate pressor responses to cholinergic agonists in the ventrolateral medullary pressor area. Brain Res. 449:1988;141-149.
44. 2 muscarinic receptor agonists produce hypotension and bradycardia when injected into the nucleus tractus solitarii. Brain Res. 477:1989;358-362.
45. Varagic V. The action of eserine on the blood pressure of the rat. Br. J. Pharmacol. 10:1955;349-353.