Characterizationof an ATP-binding cassette transporter in Cryptosporidium parvum

Molecular and Biochemical Parasitology

Volumn 87, Issue 1, 1997, Pages 117-122

  Perkins, Margaret E ^a   Volkman, Sarah ^b   Wirth, Dyann F ^b   Le Blancq, Sylvie M ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

ATP binding cassette transporter; Cryptosporidium parvum; Intracellular parasite; Transport

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CRYPTOSPORIDIUM PARVUM; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN TRANSPORT; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; MULTIDRUG RESISTANCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ABC TRANSPORTER; GLYCOPROTEIN P; PROTOZOAL DNA;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CRYPTOSPORIDIUM PARVUM; DNA, PROTOZOAN; DRUG RESISTANCE, MULTIPLE; MOLECULAR SEQUENCE DATA; P-GLYCOPROTEIN; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0030609938     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00053-4     Document Type: Article

References (17)

1. W.M. Current, L.S. Garcia, Cryptosporidiosis Clin. Microbiol. Rev. 4 (1991) 325-358.
2. U.A. Germann, P-glycoprotein - a mediator of multidrug resistance in tumour cells, Eur. J. Cancer 32 (A) (1996) 927-944.
3. D.W. Loe, R.G. Deeley, S.P.C. Cole, Biology of the multidrug resistance associated protein (MRP), Eur. J. Cancer 32 (A) (1996) 945-957.
4. A. van Helvoort, A.J. Smith, H. Sprong, I. Fritzsche, A.H. Schinkel, P. Borst, G. van Meer, MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine, Cell 87 (1996) 507-517.
5. S.J. Foote, J.K. Thompson, A.F. Cowman, D.J. Kemp, Amplification of multi-drug resistant phenotype in some chloroquine resistant isolates of P. falciparum, Cell 57 (1989) 921-930.
6. C.M. Wilson, A.E. Serrano, A.H. Wasley, A.H. Bogenschutz, A.H. Shanker, D.F. Wirth, Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum, Science 244 (1989) 1184-1186.
7. J.P. Rubio, A.F. Cowman, The ATP-binding cassette (ABC) gene family of Plasmodium falciparum, Parasitol. Today 12 (1996) 135-140.
8. S.P.C. Cole, G. Bhardwaj, J.H. Gerlach, J.E. Mackie, C.E. Grant, K.C. Almquist, A.J. Stewart, E.U. Kurz, A.M.V. Duncan, R.G. Deeley, Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line, Science 258 (1992) 1650-1654.
9. S.K. Volkman, A.F. Cowman, D.F. Wirth, Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum, Proc. Natl. Acad. Sci. USA 92 (1995) 8921-8925.
10. M.V. Nesterenko, M. Tilley, S.J. Upton, A metallo-dependent cysteine proteinase of Cryptosporidium parvum associated with the surface of sporozoites, Microbios 83 (1995) 77-88.
11. A.F. Cowman, S. Karcz, D. Galatis, J.G. Culvenor, A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole, J Cell. Biol. 113 (1991) 1033-1042.
12. D.R. Hipfner, S.D. Gauldie, R.G. Deeley, S.P.C. Cole, Detection of the 190 000 multidrug resistance-associated protein MRP, with monoclonal antibodies., Cancer Res. 54 (1994) 5788-5792.
13. S.J. Upton, M. Tilley, M.V. Nesterenko, D.B. Brillhart, A simple and reliable method of producing in vitro infections of Cryptosporidium parvum, FEMS Microbiol. Lett. 118 (1994) 45-50.
14. K. Kim, L. Gooze, C. Petersen, J. Gut, R.G. Nelson, Isolation, sequence and molecular karyotype analysis of the actin gene of Cryptosporidium parvum, Mol. Biochem. Parasitol. 50 (1992) 105-114.
15. F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, K. Struhl, Current Protocols in Molecular Biology, Wiley, New York, 1995.
16. S.M. Le Blancq, S.H. Korman, L.H.T. Van der Ploeg, Spontaneous chromosome rearrangements in the protozoan Giardia lamblia: estimation of mutation rates, Nucleic Acids Res. 20 (1992) 4539-4545.
17. Z. Etzion, M.E. Perkins, Localization of a parasite encoded protein to erythrocyte cytoplasmic vesicles of Plasmodium falciparum-infected cells, Eur. J. Cell Biol. 48 (1989) 174-179.