Differences in cation sensitivity of ligand binding to Y1 and Y2 subtype of neuropeptide Y receptor of rat brain

European Journal of Pharmacology

Volumn 318, Issue 1, 1996, Pages 193-200

  Parker, Michael S ^b   Crowley, William R ^a   Parker, Steven L ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MEMPHIS   (United States)

Author keywords

Cation regulation; Neuropeptide Y receptor; Y1 subtype; Y2 subtype

Indexed keywords

AMMONIA; BARIUM; CALCIUM; CESIUM; CHELATING AGENT; DIVALENT CATION; EDETIC ACID; EGTAZIC ACID; EPITOPE; LITHIUM; MAGNESIUM; MANGANESE; MONOVALENT CATION; NEOMYCIN; NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y RECEPTOR AGONIST; PEPTIDE YY; POTASSIUM; RECEPTOR SUBTYPE; SODIUM; SPERMIDINE; STRONTIUM;

ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN; BRAIN REGION; CONTROLLED STUDY; LIGAND BINDING; MALE; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT;

ANIMALS; CATIONS, DIVALENT; CATIONS, MONOVALENT; CHELATING AGENTS; HYPOTHALAMUS; LIGANDS; MALE; NEOMYCIN; PARIETAL LOBE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROPEPTIDE Y; SPERMIDINE;

EID: 0030604285     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00783-2     Document Type: Article

References (31)

1. Bard, J.A., M.W. Walker, T.A. Branchek and T.L. Weinshank, 1995, Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y and peptide YY, J. Biol. Chem. 270, 26762.
2. Bradford, M., 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72, 248.
3. 2A-adrenergic receptor sensitivity to allosteric modulation by monovalent cations and fully effective receptor/G-protein coupling, J. Biol. Chem. 269, 29557.
4. Clackson, T. and J.A. Wells, 1995, A hot spot of binding energy in a hormone-receptor interface, Science 267, 383.
5. Dougherty, D.A., 1996, Cation-π interactions in chemistry and biology: a new view of benzene, Phe, Tyr and Trp, Science 271, 163.
6. 3 receptor sub-type, Mol. Brain Res. 26, 320.
7. Dumont, Y., A. Fournier, S. St-Pierre and R. Quirion, 1993, Comparative characterization and autoradiographic distribution of neuropeptide Y receptor subtypes in the rat brain, J. Neurosci. 13, 73.
8. 2 radioligands, J. Pharmacol. Exp. Ther. 272, 673.
9. Eva, C., K. Keinanen, H. Monyer, P.H. Seeburg and R. Sprengel, 1990, Molecular cloning of a novel G protein-coupled receptor that may belong to the neuropeptide receptor family, FEBS Lett. 271, 81.
10. Eva, C., A. Oberto, R. Sprengel and E. Genazzani, 1992, The murine NPY-1 receptor gene. Structure and delineation of tissue-specific expression, FEBS Lett. 314, 285.
11. 1 receptor agonist, Proc. Natl. Acad. Sci. USA 87, 182.
12. 2-receptor by substituted and truncated neuropeptide-Y analogs. Identification of signal epitopes, Eur. J. Pharmacol. 232, 271.
13. 2-adrenergic receptors by sodium, J. Biol. Chem. 265, 21590.
14. Kalra, S.P. and W.R. Crowley, 1992, Neuropeptide Y: a novel neuroendocrine peptide in the control of pituitary hormone secretion and its relation to luteinizing hormone, Frontiers Neuroendocrinol. 13, 1.
15. Lundell, I., A.G. Blomqvist, M.M. Berglund, D.A. Schober, D. Johnson, M.A. Statnick, R.A. Gadski, D.R. Gehlert and D. Larhammar, 1995, Cloning of a human receptor of the neuropeptide Y receptor family with high affinity for pancreatic polypeptide and peptide YY, J. Biol. Chem. 270, 29123.
16. Minegishi, T., K. Nakamura, Y. Takakura, K. Miyamoto, Y. Hasegawa, Y. Ibuki and M. Igarashi, 1990, Biochem. Biophys. Res. Commun. 172, 1049.
17. Munson, P.J. and D. Rodbard, 1980, LIGAND: a versatile computerized approach for characterization of ligand-binding proteins, Anal. Biochem. 107, 220.
18. Oblatt-Montal, M., L.K. Buhler, T. Iwamoto, J.M. Tomich and M. Montal, 1993, Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. I. Transmembrane segment M2 of the nicotinic cholinergic receptor channel is a key pore-lining structure, J. Biol. Chem. 268, 14601.
19. O'Donohue, T.L., B.A. Chronwall, R.M. Pruss, E. Mezey, J.Z. Kiss, L.E. Eiden, V.J. Massari, R.E. Tessel, V.M. Pickel, D.A. DiMaggio, A.J. Hotchkiss and W.R. Crowley, 1985, Neuropeptide Y and peptide YY neuronal and endocrine systems, Peptides 6, 755.
20. Parker, S.L., S.P. Kalra and W.R. Crowley, 1991, Neuropeptide Y modulates the binding of a gonadotropin-releasing hormone (GnRH) analog to anterior pituitary GnRH receptor sites, Endocrinology 128, 2309.
21. Pearson, W.R., 1990, Rapid and sensitive sequence comparisons with FASTP and FASTA, Methods Enzymol. 183, 63.
22. Quintana, J., H. Wang and M. Ascoli, 1993, The regulation of the binding affinity of the luteinizing hormone/choriogonadotropin receptor by sodium ions is mediated by a highly conserved aspartate located in the second transmembrane domain of G protein-coupled receptors, Mol. Endocrinol. 7, 767.
23. Rose, P.M., P. Fernandes, J.S. Lynch, S.T. Frazier, S.M. Fisher, K. Kodukula, B. Kienzle and R. Seethala, 1995, Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor, J. Biol. Chem. 270, 22661.
24. Segel, I.W., 1976, Biochemical Calculations, 2nd edn. (Wiley and Sons, New York, NY) p. 311.
25. Sokal, R.R. and F.J. Rohlf, 1990, Biometry (Freeman, San Francisco, CA) p. 469.
26. 1 receptor mediating this peptide's effect, Peptides 13, 581.
27. 2+-dependent regulation of presynaptic stimulus-secretion coupling, J. Neurochem. 53, 1188.
28. Wahlestedt, C. and D.J. Reis, 1993, Neuropeptide Y-related peptides and their receptors - are the receptors potential therapeutic drug targets?, Annu. Rev. Pharmacol. Toxicol. 32, 309.
29. Walker, M.W., D.A. Ewald, T.M. Perney and R.J. Miller, 1988, Neuropeptide Y modulates neurotransmitter release and Ca2+ currents in rat sensory neurons, J. Neurosci. 8, 2438.
30. Walker, P., M. Munoz, R. Martinez and M.C. Peitsch, 1994, Acidic residues in extracellular loops of the human Y1 neuropeptide Y receptor are essential for ligand binding, J. Biol. Chem. 269, 2863.
31. Weast, R.C., ed., 1982, Handbook of Chemistry and Physics, 63rd edn. (CRC Press, Boca Raton, FL) p. F-179.