메뉴 건너뛰기




Volumn 226, Issue 2, 1996, Pages 362-373

Central nervous system expression of HIV-1 gp120 activates the hypothalamic-pituitary-adrenal axis: Evidence for involvement of NMDA receptors and nitric oxide synthase

Author keywords

[No Author keywords available]

Indexed keywords

ARGIPRESSIN; CORTICOSTERONE; CORTICOTROPIN; ENVELOPE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE SYNTHASE;

EID: 0030589548     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0664     Document Type: Article
Times cited : (54)

References (57)
  • 1
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of l-κB synthesis
    • Auphan, M., DiDonato, J. A., Rosette, C., Helmberg, A., and Karin, M. (1995). Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of l-κB synthesis. Science 270, 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, M.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 2
    • 0021342361 scopus 로고
    • Effects of vasopressin antiserum on the response of adrenocorticotropin and cortisol to hemorrhage
    • Carlsson, D. E., and Gann, D. S. (1994). Effects of vasopressin antiserum on the response of adrenocorticotropin and cortisol to hemorrhage. Endocrinology 114, 317-324.
    • (1994) Endocrinology , vol.114 , pp. 317-324
    • Carlsson, D.E.1    Gann, D.S.2
  • 4
    • 0026452465 scopus 로고
    • Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants
    • Costa, A., Yasin, S. A., Hucks, D., Forsling, M. L., Besser, G. M., and Grossman, A. (1992). Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants. Endocrinology 131, 2595-2602.
    • (1992) Endocrinology , vol.131 , pp. 2595-2602
    • Costa, A.1    Yasin, S.A.2    Hucks, D.3    Forsling, M.L.4    Besser, G.M.5    Grossman, A.6
  • 5
    • 0027480439 scopus 로고
    • Human immunodeficiency virus type I coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures
    • Dawson, V. L., Dawson, T. M., Uhl, G. R., and Snyder, S. H. (1993). Human immunodeficiency virus type I coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proc. Natl. Acad. Sci. USA 90, 3256-3259.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3256-3259
    • Dawson, V.L.1    Dawson, T.M.2    Uhl, G.R.3    Snyder, S.H.4
  • 6
    • 0028090459 scopus 로고
    • Gp120 neurotoxicity in primary cortical cultures
    • Dawson, T. M., and Dawson, V. L. (1994). Gp120 neurotoxicity in primary cortical cultures. Adv. Neuroimmunol. 4, 167-173.
    • (1994) Adv. Neuroimmunol. , vol.4 , pp. 167-173
    • Dawson, T.M.1    Dawson, V.L.2
  • 7
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
    • Dawson, V. L., Kizushi, V. M., Huang, P. L., Snyder, S. H., and Dawson, T. M. (1996). Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J. Neurosci. 16, 2479-2487.
    • (1996) J. Neurosci. , vol.16 , pp. 2479-2487
    • Dawson, V.L.1    Kizushi, V.M.2    Huang, P.L.3    Snyder, S.H.4    Dawson, T.M.5
  • 8
    • 0023765738 scopus 로고
    • Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy
    • DeLeon, M., McRae, T., and Tsai, J. R. (1988). Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy. Lancet ii, 391-392.
    • (1988) Lancet , vol.2 , pp. 391-392
    • DeLeon, M.1    McRae, T.2    Tsai, J.R.3
  • 9
    • 0028833577 scopus 로고
    • Differential activation of adrenal steroid receptors in neural and immune tissues of Sprague Dawley, Fischer 344, and Lewis rats
    • Dhabhar, F. S., Miller, A. H., McEwen, B. S., and Spencer, R. L. (1995). Differential activation of adrenal steroid receptors in neural and immune tissues of Sprague Dawley, Fischer 344, and Lewis rats. J. Neuroimmunol. 56, 77-90.
    • (1995) J. Neuroimmunol. , vol.56 , pp. 77-90
    • Dhabhar, F.S.1    Miller, A.H.2    McEwen, B.S.3    Spencer, R.L.4
  • 11
    • 0025809711 scopus 로고
    • N-Methyl-D-Aspartate treatment increases circulating adrenocorticotropin and luteinizing hormone in the rat
    • Farah, J. M. J., Tadimeti, S., Rao, S., Mick, S. J., Coyne, K. E., and Iyengar, S. (1991). N-Methyl-D-Aspartate treatment increases circulating adrenocorticotropin and luteinizing hormone in the rat. Endocrinology 128, 1875-1880.
    • (1991) Endocrinology , vol.128 , pp. 1875-1880
    • Farah, J.M.J.1    Tadimeti, S.2    Rao, S.3    Mick, S.J.4    Coyne, K.E.5    Iyengar, S.6
  • 12
    • 0023240251 scopus 로고
    • N-Methyl-D,L-aspartate elicits hypothalamic gonadotropin-releasing hormone release in preburtal male rhesus monkeys (Macaca mulatta)
    • Gay, V. L., and Plant, T. M. (1987). N-Methyl-D,L-aspartate elicits hypothalamic gonadotropin-releasing hormone release in preburtal male rhesus monkeys (Macaca mulatta). Endocrinology 120, 2289-2296.
    • (1987) Endocrinology , vol.120 , pp. 2289-2296
    • Gay, V.L.1    Plant, T.M.2
  • 13
    • 0023672755 scopus 로고
    • Effects of immunoneutralization of corticotropin-releasing hormone, adrenocorticotropin and beta-endorphin in the surgically stressed rat
    • Giuffre, K. A., Udelsman, R., Listwak, S., and Chrousos, P. (1988). Effects of immunoneutralization of corticotropin-releasing hormone, adrenocorticotropin and beta-endorphin in the surgically stressed rat. Endocrinology 122, 306-310.
    • (1988) Endocrinology , vol.122 , pp. 306-310
    • Giuffre, K.A.1    Udelsman, R.2    Listwak, S.3    Chrousos, P.4
  • 14
    • 0024210421 scopus 로고
    • Corticotropin-releasing hormone and pituitary-adrenocortical responses in chronically stressed rats
    • Hashimoto, K., Suemaru, S., Takao, T., Sugawara, M., Makino, S., and Fensuka, O. (1988). Corticotropin-releasing hormone and pituitary-adrenocortical responses in chronically stressed rats. Reg. Pept. 23, 117-126.
    • (1988) Reg. Pept. , vol.23 , pp. 117-126
    • Hashimoto, K.1    Suemaru, S.2    Takao, T.3    Sugawara, M.4    Makino, S.5    Fensuka, O.6
  • 15
    • 0023772753 scopus 로고
    • Corticotropin-releasing factor receptors and pituitary adrenal response during immobilization stress
    • Hauger, R. L., Millar, M. A., Lorang, M., Harwood, J. P., and Aguilera, G. (1988). Corticotropin-releasing factor receptors and pituitary adrenal response during immobilization stress. Endocrinology 123, 396-404.
    • (1988) Endocrinology , vol.123 , pp. 396-404
    • Hauger, R.L.1    Millar, M.A.2    Lorang, M.3    Harwood, J.P.4    Aguilera, G.5
  • 16
    • 0025248497 scopus 로고
    • Sigma receptors modulate the hypothalamic-pituitary-adrenal (HPA) axis centrally: Evidence for a functional interaction with NMDA receptors, in vivo
    • Iyengar, S., Mick, S., Dilworth, V., Michel, J., Rao, T. S., Farah, J. M., and Wood, P. L. (1990). Sigma receptors modulate the hypothalamic-pituitary-adrenal (HPA) axis centrally: Evidence for a functional interaction with NMDA receptors, in vivo. Neuropharmacology 29, 299-303.
    • (1990) Neuropharmacology , vol.29 , pp. 299-303
    • Iyengar, S.1    Mick, S.2    Dilworth, V.3    Michel, J.4    Rao, T.S.5    Farah, J.M.6    Wood, P.L.7
  • 17
    • 0025998713 scopus 로고
    • Stimulation of adrenocorticotropin but not prolactin and catecholamine release by N-methyl-aspartic acid
    • Jezova, D., Oliver, C., and Jurcovicova, J. (1991). Stimulation of adrenocorticotropin but not prolactin and catecholamine release by N-methyl-aspartic acid. Neuroendocrinology 54, 488-492.
    • (1991) Neuroendocrinology , vol.54 , pp. 488-492
    • Jezova, D.1    Oliver, C.2    Jurcovicova, J.3
  • 18
    • 0023485043 scopus 로고
    • Modulation of brain aging correlates by long-term alterations of adrenal steroids and neurally-active peptides
    • Landfield, P. W. (1987). Modulation of brain aging correlates by long-term alterations of adrenal steroids and neurally-active peptides. Prog. Brain Res. 72, 279-300.
    • (1987) Prog. Brain Res. , vol.72 , pp. 279-300
    • Landfield, P.W.1
  • 19
    • 0025998928 scopus 로고
    • Effects of N-methyl-D,L-aspartate on β-endorphin and prolactin secretion in rams exposed to long or short days
    • Lincoln, G. A., and Wu, F. C. W. (1991). Effects of N-methyl-D,L-aspartate on β-endorphin and prolactin secretion in rams exposed to long or short days. J. Endocrinol. 5, 483-490.
    • (1991) J. Endocrinol. , vol.5 , pp. 483-490
    • Lincoln, G.A.1    Wu, F.C.W.2
  • 20
    • 0027194540 scopus 로고
    • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
    • Lipton, S. A., Choi, Y. B., Pan, Z. H., Lei, S. Z., Chen, H. S., Sucher, N. J., Loscalco, J., Singel, D. J., and Stamler, J. S. (1993). A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364, 626-632.
    • (1993) Nature , vol.364 , pp. 626-632
    • Lipton, S.A.1    Choi, Y.B.2    Pan, Z.H.3    Lei, S.Z.4    Chen, H.S.5    Sucher, N.J.6    Loscalco, J.7    Singel, D.J.8    Stamler, J.S.9
  • 21
    • 0028421758 scopus 로고
    • HIV-related neuronal injury
    • Lipton, S. A. (1994). HIV-related neuronal injury. Mol. Neurobiol. 8, 181-196.
    • (1994) Mol. Neurobiol. , vol.8 , pp. 181-196
    • Lipton, S.A.1
  • 23
    • 0027055318 scopus 로고
    • Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type I gp120
    • McKeating, J. A., Cordell, J., Dean, C. J., and Balfe, P. (1992). Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type I gp120. Virology 191, 732-742.
    • (1992) Virology , vol.191 , pp. 732-742
    • McKeating, J.A.1    Cordell, J.2    Dean, C.J.3    Balfe, P.4
  • 24
    • 0027492106 scopus 로고
    • Quantitative mapping of glutamate presynaptic terminals in the supraoptic nucleus and surrounding hypothalamus
    • Meeker, R. B., Swanson, D. J., Greenwood, R. S., and Hayward, J. N. (1993). Quantitative mapping of glutamate presynaptic terminals in the supraoptic nucleus and surrounding hypothalamus. Brain Res. 600, 112-122.
    • (1993) Brain Res. , vol.600 , pp. 112-122
    • Meeker, R.B.1    Swanson, D.J.2    Greenwood, R.S.3    Hayward, J.N.4
  • 25
    • 0028167677 scopus 로고
    • HIV coating gp120 glycoprotein-dependent prostaglandin E2 release by human cultured astrocytoma cells is regulated by nitric oxide formation
    • Mollace, V., Colasanti, M., Rodino, P., Lauro, G. M., and Nistico, G. (1994). HIV coating gp120 glycoprotein-dependent prostaglandin E2 release by human cultured astrocytoma cells is regulated by nitric oxide formation. Biochem. Biophys. Res. Commun. 203, 87-92.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 87-92
    • Mollace, V.1    Colasanti, M.2    Rodino, P.3    Lauro, G.M.4    Nistico, G.5
  • 27
    • 0028174093 scopus 로고
    • Effects of excitatory amino acid transmitters on hypothalamic corticotropin-releasing hormone (CRH) and arginine-vasopressin (AVP) release in vitro: Implications in pituitary-adrenal regulation
    • Patchev, V. K., Karalis, K., and Chrousos, G. P. (1994). Effects of excitatory amino acid transmitters on hypothalamic corticotropin-releasing hormone (CRH) and arginine-vasopressin (AVP) release in vitro: Implications in pituitary-adrenal regulation. Brain Res. 633, 312-316.
    • (1994) Brain Res. , vol.633 , pp. 312-316
    • Patchev, V.K.1    Karalis, K.2    Chrousos, G.P.3
  • 28
    • 0028010766 scopus 로고
    • gp120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages
    • Pietraforte, D., Tritarelli, E., Testa, U., and Minetti, M. (1994). gp120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages. J. Leukocyte Biol. 55, 175-182.
    • (1994) J. Leukocyte Biol. , vol.55 , pp. 175-182
    • Pietraforte, D.1    Tritarelli, E.2    Testa, U.3    Minetti, M.4
  • 29
    • 0028032938 scopus 로고
    • HIV-1 envelope protein gp120 potentiates NMDA-evoked noradrenaline release by a direct action at rat hippocampal and cortical noradrenergic nerve endings
    • Pittaluga, A., and Raiteri, M. (1994). HIV-1 envelope protein gp120 potentiates NMDA-evoked noradrenaline release by a direct action at rat hippocampal and cortical noradrenergic nerve endings. Eur. J. Neurosci. 6, 1743-1749.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1743-1749
    • Pittaluga, A.1    Raiteri, M.2
  • 30
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou, S., Pou, W. S., Bredt, D. S., Snyder, S. H., and Rosen, G. M. (1992). Generation of superoxide by purified brain nitric oxide synthase. J. Biol. Chem. 267, 24173-24176.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.S.2    Bredt, D.S.3    Snyder, S.H.4    Rosen, G.M.5
  • 31
    • 0026583465 scopus 로고
    • Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
    • Przedborski, S., Kostic, V., Jackson-Lewis, V., Naini, A. B., Simonetti, S., Fahn, S., Carlson, E., Epstein, C. J., and Cadet, J. L. (1992). Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. J. Neurosci. 12, 1658-1667.
    • (1992) J. Neurosci. , vol.12 , pp. 1658-1667
    • Przedborski, S.1    Kostic, V.2    Jackson-Lewis, V.3    Naini, A.B.4    Simonetti, S.5    Fahn, S.6    Carlson, E.7    Epstein, C.J.8    Cadet, J.L.9
  • 33
    • 0028176588 scopus 로고
    • IL-1β potentiates the acetylcholine-induced release of vasopressin from the hypothalamus in vitro, but not from the amygdala
    • Raber, J., Merlo Pich, E. M., Koob, G. F., and Bloom, F. E. (1994). IL-1β potentiates the acetylcholine-induced release of vasopressin from the hypothalamus in vitro, but not from the amygdala. Neuroendocrinology 59, 208-217.
    • (1994) Neuroendocrinology , vol.59 , pp. 208-217
    • Raber, J.1    Merlo Pich, E.M.2    Koob, G.F.3    Bloom, F.E.4
  • 34
    • 0028967421 scopus 로고
    • The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product
    • Refaeli, Y., Levy, D. N., and Weiner, D. B. (1995). The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product. Proc. Natl. Acad. Sci. USA 92, 3621-3625.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3621-3625
    • Refaeli, Y.1    Levy, D.N.2    Weiner, D.B.3
  • 35
    • 0027921994 scopus 로고
    • Neuroendocrine-immune interactions
    • Reichlin, S. (1993). Neuroendocrine-immune interactions. N. Engl. J. Med. 329, 1246-1253.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1246-1253
    • Reichlin, S.1
  • 36
    • 0025159919 scopus 로고
    • Unexpected inhibitory action of N-methyl-D,L-aspartate on luteinizing hormone release in adult ovariectomized rhesus monkeys: A role for the hypothalamic-adrenal axis
    • Reyes, A., Luckhaus, J., and Ferin, M. (1990). Unexpected inhibitory action of N-methyl-D,L-aspartate on luteinizing hormone release in adult ovariectomized rhesus monkeys: A role for the hypothalamic-adrenal axis. Endocrinology 127, 724-729.
    • (1990) Endocrinology , vol.127 , pp. 724-729
    • Reyes, A.1    Luckhaus, J.2    Ferin, M.3
  • 37
    • 0028943167 scopus 로고
    • Influence of immune signals on the hypothalamic-pituitary axis of the rodent
    • Rivier, C. (1995). Influence of immune signals on the hypothalamic-pituitary axis of the rodent. Frontiers Neuroendocrinol. 16, 151-182.
    • (1995) Frontiers Neuroendocrinol. , vol.16 , pp. 151-182
    • Rivier, C.1
  • 39
    • 0025775936 scopus 로고
    • Evidence for a specific role of vasporessin in sustaining pituitary-adrenocortical stress response in the rat
    • Scaccianoce, S., Muscolo, L. A. A., Gigliana, G., Navarra, D., Nicolai, R., and Angelucci, L. (1991). Evidence for a specific role of vasporessin in sustaining pituitary-adrenocortical stress response in the rat. Endocrinology 128, 3138-3143.
    • (1991) Endocrinology , vol.128 , pp. 3138-3143
    • Scaccianoce, S.1    Muscolo, L.A.A.2    Gigliana, G.3    Navarra, D.4    Nicolai, R.5    Angelucci, L.6
  • 40
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I-KBaα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R. I., Cogswell, P. C., Lofquist, A. K., and Baldwin, A. S., Jr. (1995). Role of transcriptional activation of I-KBaα in mediation of immunosuppression by glucocorticoids. Science 270, 283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin A.S., Jr.4
  • 41
    • 0029040938 scopus 로고
    • Axonal growth and fasculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells
    • Segal, R. A., Pomeroy, S. L., and Stiles, C. D. (1995). Axonal growth and fasculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells. J. Neurosci. 15, 4970-4981.
    • (1995) J. Neurosci. , vol.15 , pp. 4970-4981
    • Segal, R.A.1    Pomeroy, S.L.2    Stiles, C.D.3
  • 42
    • 0015958924 scopus 로고
    • Radioimmunoassay of arginine vasopressin in serum: Development and application
    • Skowsky, W., Rosembloom, A. A., and Fisher, D. A. (1974). Radioimmunoassay of arginine vasopressin in serum: Development and application. J. Cell. Endocrinol. Metab. 38, 278-287.
    • (1974) J. Cell. Endocrinol. Metab. , vol.38 , pp. 278-287
    • Skowsky, W.1    Rosembloom, A.A.2    Fisher, D.A.3
  • 44
    • 0028970281 scopus 로고
    • Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus
    • Smith, M. A., Makino, S., Kvetnansky, R., and Post, R. M. (1995). Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J. Neurosci. 15, 1768-1777.
    • (1995) J. Neurosci. , vol.15 , pp. 1768-1777
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3    Post, R.M.4
  • 45
    • 0026463945 scopus 로고
    • Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome
    • Starkman, M. N., Gebarski, S. S., Berent, S., and Schteingart, D. E. (1992). Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome. Biol. Psychiatry 32, 756-765.
    • (1992) Biol. Psychiatry , vol.32 , pp. 756-765
    • Starkman, M.N.1    Gebarski, S.S.2    Berent, S.3    Schteingart, D.E.4
  • 46
    • 0344239828 scopus 로고
    • Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats
    • Sternberg, E. M., Hill, J. M., Chrousos, G. P., Kamilaris, T., Listwak, S. J., Gold, P. W., and Wilder, R. L. (1989). Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats. Proc. Natl. Acad. Sci. USA 86, 2374-2378.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2374-2378
    • Sternberg, E.M.1    Hill, J.M.2    Chrousos, G.P.3    Kamilaris, T.4    Listwak, S.J.5    Gold, P.W.6    Wilder, R.L.7
  • 47
    • 0028009187 scopus 로고
    • Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice
    • Toggas, S. M., Masliah, E., Rockenstein, E. M., Rall, G. F., Abraham, C. R., and Mucke, L. (1994). Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature 367, 188-193.
    • (1994) Nature , vol.367 , pp. 188-193
    • Toggas, S.M.1    Masliah, E.2    Rockenstein, E.M.3    Rall, G.F.4    Abraham, C.R.5    Mucke, L.6
  • 48
    • 0030059754 scopus 로고    scopus 로고
    • Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine
    • Toggas, S. M., Masliah, E., and Mucke, L. (1996a). Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine. Brain Res. 706, 303-307.
    • (1996) Brain Res. , vol.706 , pp. 303-307
    • Toggas, S.M.1    Masliah, E.2    Mucke, L.3
  • 49
    • 85030289799 scopus 로고    scopus 로고
    • Transgenic animal models to assess the pathogenic potential of viral products in HIV-1 associated CNS disease
    • (H. E. Gendelman, S. Lipton, L. Epstein, and S. Swindells, Eds.), Chapmann and Hall, New York, in press
    • Toggas, S. M., and Mucke, L. (1996b). Transgenic animal models to assess the pathogenic potential of viral products in HIV-1 associated CNS disease. In "Neurological and Neuropsychiatric Manifestations of HIV-1 Infections" (H. E. Gendelman, S. Lipton, L. Epstein, and S. Swindells, Eds.), Chapmann and Hall, New York, in press.
    • (1996) Neurological and Neuropsychiatric Manifestations of HIV-1 Infections
    • Toggas, S.M.1    Mucke, L.2
  • 50
    • 0030071721 scopus 로고    scopus 로고
    • Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway
    • Troy, C. M., Derossi, D., Prochiantz, A., Greene, L. A., and Shelanski, M. L. (1996). Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway. J. Neurosci. 16, 253-261.
    • (1996) J. Neurosci. , vol.16 , pp. 253-261
    • Troy, C.M.1    Derossi, D.2    Prochiantz, A.3    Greene, L.A.4    Shelanski, M.L.5
  • 52
    • 0025635709 scopus 로고
    • Glutamate, the dominant excitatory transmitter in neuroendocrine regulation
    • van den Pol, A. N., Wuarin, J., and Dudek, F. E. (1990). Glutamate, the dominant excitatory transmitter in neuroendocrine regulation. Science 250, 1276-1278.
    • (1990) Science , vol.250 , pp. 1276-1278
    • Van Den Pol, A.N.1    Wuarin, J.2    Dudek, F.E.3
  • 53
    • 0018131622 scopus 로고
    • The effect of hemorrhage and hypertonic saline upon plasma oxytocin and arginine vasopressin in conscious dogs
    • Weitzman, R., Glatz, T. H., and Fisher, D. A. (1978). The effect of hemorrhage and hypertonic saline upon plasma oxytocin and arginine vasopressin in conscious dogs. Endocrinology 103, 2154.
    • (1978) Endocrinology , vol.103 , pp. 2154
    • Weitzman, R.1    Glatz, T.H.2    Fisher, D.A.3
  • 54
    • 0028979136 scopus 로고
    • Glucocorticoids and immune function: Physiological relevance and pathogenic potential of hormonal dysfunction
    • Wilckens, T. (1995). Glucocorticoids and immune function: Physiological relevance and pathogenic potential of hormonal dysfunction. Trends Pharmacol. Sci. 16, 193-197.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 193-197
    • Wilckens, T.1
  • 55
    • 0029077755 scopus 로고
    • Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β-1
    • Wyss-Coray, T., Feng, L., Masliah, E., Ruppe, M. D., Lee, H. S., Toggas, S. M., and Flockenstein, E. M. (1995). Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β-1. Am. J. Pathol. 147, 53-67.
    • (1995) Am. J. Pathol. , vol.147 , pp. 53-67
    • Wyss-Coray, T.1    Feng, L.2    Masliah, E.3    Ruppe, M.D.4    Lee, H.S.5    Toggas, S.M.6    Flockenstein, E.M.7
  • 56
    • 0030019995 scopus 로고    scopus 로고
    • Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis
    • Wyss-Coray, T., Masliah, E., Toggas, S. M., Rockenstein, E. M., Brooker, M. J., Suk Lee, H., and Mucke, L. (1996). Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis. J. Clin. Invest. 97, 789-790.
    • (1996) J. Clin. Invest. , vol.97 , pp. 789-790
    • Wyss-Coray, T.1    Masliah, E.2    Toggas, S.M.3    Rockenstein, E.M.4    Brooker, M.J.5    Suk Lee, H.6    Mucke, L.7
  • 57
    • 0029900905 scopus 로고    scopus 로고
    • Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury
    • Xia, Y., Dawson, V. L., Dawson, T. M., Snyder, S. H., and Zweier, J. L. (1996). Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proc. Natl. Acad. Sci. USA 95, 6770-6774.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6770-6774
    • Xia, Y.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4    Zweier, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.