-
1
-
-
0023619243
-
Antibody directed enzymes revive anti-cancer prodrugs concept
-
[1] Bagshawe, K.D. (1987) Antibody directed enzymes revive anti-cancer prodrugs concept. Br. J. Cancer 56, 531-532.
-
(1987)
Br. J. Cancer
, vol.56
, pp. 531-532
-
-
Bagshawe, K.D.1
-
2
-
-
0024246527
-
A cytotoxic agent can be generated selectively at cancer sites
-
[2] Bagshawe, K.D., Springer, C.J., Searle, F., Antoniw, P., Sharma, S.K., Melton, R.G. and Sherwood, R.F. (1988) A cytotoxic agent can be generated selectively at cancer sites. Br. J. Cancer 58, 700-703.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 700-703
-
-
Bagshawe, K.D.1
Springer, C.J.2
Searle, F.3
Antoniw, P.4
Sharma, S.K.5
Melton, R.G.6
Sherwood, R.F.7
-
3
-
-
0024041278
-
Anti-tumour effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate
-
[3] Senter, P.D., Saulnier, M.G., Schreiber, G.J., Hirschberg, D.L., Brown, J.P., Hellstrom, I. and Hellstrom, K.E. (1988) Anti-tumour effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate. Proc. Natl. Acad. Sci. USA 85, 4842-4846.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4842-4846
-
-
Senter, P.D.1
Saulnier, M.G.2
Schreiber, G.J.3
Hirschberg, D.L.4
Brown, J.P.5
Hellstrom, I.6
Hellstrom, K.E.7
-
4
-
-
0025720744
-
Antibody directed enzyme prodrug therapy (ADEPT) - A three-phase system
-
[4] Sharma, S.K., Bagshawe, K.D., Springer, C.J., Burke, P.J., Rogers, G.T., Boden, J.A., Antoniw, P., Melton, R.G. and Sherwood, R.F. (1991) Antibody directed enzyme prodrug therapy (ADEPT) - A three-phase system. Dis. Markers 9, 225-231.
-
(1991)
Dis. Markers
, vol.9
, pp. 225-231
-
-
Sharma, S.K.1
Bagshawe, K.D.2
Springer, C.J.3
Burke, P.J.4
Rogers, G.T.5
Boden, J.A.6
Antoniw, P.7
Melton, R.G.8
Sherwood, R.F.9
-
5
-
-
0025720558
-
Antibody directed enzyme prodrug therapy (ADEPT) - Clinical report
-
[5] Bagshawe, K.D., Sharma, S.K., Springer, C.J., Antoniw, P., Boden, J.A., Rogers, G.T., Burke, P.J., Melton, R.G. and Sherwood, R.F. (1991) Antibody directed enzyme prodrug therapy (ADEPT) - Clinical report. Dis. Markers 9, 233-238.
-
(1991)
Dis. Markers
, vol.9
, pp. 233-238
-
-
Bagshawe, K.D.1
Sharma, S.K.2
Springer, C.J.3
Antoniw, P.4
Boden, J.A.5
Rogers, G.T.6
Burke, P.J.7
Melton, R.G.8
Sherwood, R.F.9
-
6
-
-
0002726158
-
Antibody-directed enzyme prodrug therapy: A pilot-scale clinical trial
-
[6] Bagshawe, K.D., Sharma, S.K., Springer, C.J. and Antoniw, P. (1995) Antibody-directed enzyme prodrug therapy: a pilot-scale clinical trial. Tumour Targeting 1, 1-13.
-
(1995)
Tumour Targeting
, vol.1
, pp. 1-13
-
-
Bagshawe, K.D.1
Sharma, S.K.2
Springer, C.J.3
Antoniw, P.4
-
7
-
-
0021999401
-
Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy
-
[7] Schroff, R.W., Foon, K.A., Beatty, S.M., Oldham, R.K. and Morgan, A.C. (1985) Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy. Cancer Res. 45, 879.
-
(1985)
Cancer Res.
, vol.45
, pp. 879
-
-
Schroff, R.W.1
Foon, K.A.2
Beatty, S.M.3
Oldham, R.K.4
Morgan, A.C.5
-
8
-
-
0028107507
-
Human immune response to monoclonal antibodies
-
[8] Khazaeli, M.B., Conry, R.M. and Lobuglio, A.F. (1994) Human immune response to monoclonal antibodies. J. Immunother. 15(1), 42-52.
-
(1994)
J. Immunother.
, vol.15
, Issue.1
, pp. 42-52
-
-
Khazaeli, M.B.1
Conry, R.M.2
Lobuglio, A.F.3
-
9
-
-
0028175501
-
Human anti-mouse antibody response in cancer patients following single low-dose injections of radiolabelled murine monoclonal antibodies
-
[9] Dillman, R.O., Shawler, D.L., McCallister, T.J. and Halpern, S.E. (1994) Human anti-mouse antibody response in cancer patients following single low-dose injections of radiolabelled murine monoclonal antibodies. Cancer Biother. 9(1), 17-28.
-
(1994)
Cancer Biother.
, vol.9
, Issue.1
, pp. 17-28
-
-
Dillman, R.O.1
Shawler, D.L.2
McCallister, T.J.3
Halpern, S.E.4
-
10
-
-
0017750562
-
Effects of the new anti-lymphocyte peptide cyclosporin A in animals
-
[10] Borel, J.F., Feurer, C., Magnee, C. and Stahelin, H. (1977) Effects of the new anti-lymphocyte peptide cyclosporin A in animals. Immunology 32, 1017.
-
(1977)
Immunology
, vol.32
, pp. 1017
-
-
Borel, J.F.1
Feurer, C.2
Magnee, C.3
Stahelin, H.4
-
11
-
-
0019223156
-
The effect of cyclosporin a on the primary and secondary immune response in the rabbit
-
[11] Lindsey, N.J., Harris, K.R., Norman, H.B., Smith, J.L., Lee, H.A. and Slapek, M. (1982) The effect of cyclosporin A on the primary and secondary immune response in the rabbit. Transplant. Proc. 12, 252.
-
(1982)
Transplant. Proc.
, vol.12
, pp. 252
-
-
Lindsey, N.J.1
Harris, K.R.2
Norman, H.B.3
Smith, J.L.4
Lee, H.A.5
Slapek, M.6
-
12
-
-
0024261744
-
Cyclosporin a prevents the anti-immune antibody response to a monoclonal anti-tumour antibody in rabbits
-
[12] Ledermann, J.A., Begent, R.H.J. and Bagshawe, K.D. (1988) Cyclosporin A prevents the anti-immune antibody response to a monoclonal anti-tumour antibody in rabbits. Br. J. Cancer 58, 562.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 562
-
-
Ledermann, J.A.1
Begent, R.H.J.2
Bagshawe, K.D.3
-
13
-
-
0024255859
-
Repeated anti-tumour antibody therapy in man with suppression of the host response by cyclosporin A
-
[13] Ledermann, J.A., Begent, R.H.J., Bagshawe, K.D., Riggs, S.J., Dearle, F., Glaser, M.G., Green, A.J. and Dale, R.G. (1988) Repeated anti-tumour antibody therapy in man with suppression of the host response by cyclosporin A. Br. J. Cancer 58, 654-657.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 654-657
-
-
Ledermann, J.A.1
Begent, R.H.J.2
Bagshawe, K.D.3
Riggs, S.J.4
Dearle, F.5
Glaser, M.G.6
Green, A.J.7
Dale, R.G.8
-
14
-
-
0029838044
-
Effect of cyclosporin A on immunogenicity of a bacterial enzyme carboxypeptidase G2 in ADEPT
-
in press
-
[14] Sharma, S.K., Bagshawe, K.D., Melton, R.G. and Begent, R.H.J. (1996) Effect of cyclosporin A on immunogenicity of a bacterial enzyme carboxypeptidase G2 in ADEPT. Transplant. Proc., in press.
-
(1996)
Transplant. Proc.
-
-
Sharma, S.K.1
Bagshawe, K.D.2
Melton, R.G.3
Begent, R.H.J.4
-
15
-
-
0026900387
-
Human immune response to monoclonal antibody-enzyme conjugates in ADEPT. Pilot clinical trial
-
[15] Sharma, S.K., Bagshawe. K.D., Melton, R.G. and Sherwood, R.F. (1993) Human immune response to monoclonal antibody-enzyme conjugates in ADEPT. Pilot clinical trial. Cell Biophys. 21, 109-119.
-
(1993)
Cell Biophys.
, vol.21
, pp. 109-119
-
-
Sharma, S.K.1
Bagshawe, K.D.2
Melton, R.G.3
Sherwood, R.F.4
-
16
-
-
84889555394
-
ADEPT: Clinical study with cyclosporin A to allow multiple cycles of therapy
-
in press
-
[16] Bagshawe, K.D. and Sharma, S.K. (1996) ADEPT: Clinical study with cyclosporin A to allow multiple cycles of therapy. Transplant. Proc., in press.
-
(1996)
Transplant. Proc.
-
-
Bagshawe, K.D.1
Sharma, S.K.2
-
17
-
-
0021352277
-
Diagnosis and therapy for solid tumours with radiolabelled antibodies and immune fragments
-
[17] Carrasquillo, J.A., Krohn, K.A., Beaumier, P. et al. (1984) Diagnosis and therapy for solid tumours with radiolabelled antibodies and immune fragments. Cancer Treat. Rep. 68, 317.
-
(1984)
Cancer Treat. Rep.
, vol.68
, pp. 317
-
-
Carrasquillo, J.A.1
Krohn, K.A.2
Beaumier, P.3
-
18
-
-
0030163020
-
Radioimmunotherapy of medullary-thyroid cancer with iodine-131-labelled anti-CEA antibodies
-
[18] Juweid, M., Sharkey, R.M., Behr, T. et al. (1996) Radioimmunotherapy of medullary-thyroid cancer with iodine-131-labelled anti-CEA antibodies. J. Nucl. Med. 37(6), 905-911.
-
(1996)
J. Nucl. Med.
, vol.37
, Issue.6
, pp. 905-911
-
-
Juweid, M.1
Sharkey, R.M.2
Behr, T.3
-
19
-
-
0342530626
-
Mouse/human chimeric monoclonal antibody in man: Kinetics and immune response
-
[19] Lobuglio, A.F., Wheeler, R.H., Trang, J., Haynes, A., Rogers, K., Harvey, E.B., Sun, L., Ghrayeb, J. and Khazaeli, M.B. (1989) Mouse/human chimeric monoclonal antibody in man: kinetics and immune response. Proc. Natl. Acad. Sci. USA 86, 4220-4224.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 4220-4224
-
-
Lobuglio, A.F.1
Wheeler, R.H.2
Trang, J.3
Haynes, A.4
Rogers, K.5
Harvey, E.B.6
Sun, L.7
Ghrayeb, J.8
Khazaeli, M.B.9
-
20
-
-
0029057209
-
Genetically-engineered antibodies and their application to brain delivery
-
[20] Morrison, S.L. and Shin, S.U. (1995) Genetically-engineered antibodies and their application to brain delivery. Adv. Drug Deliv. Rev. 15(1-3), 147-175.
-
(1995)
Adv. Drug Deliv. Rev.
, vol.15
, Issue.1-3
, pp. 147-175
-
-
Morrison, S.L.1
Shin, S.U.2
-
21
-
-
0027477134
-
Phase I trial of chimeric (human-mouse) monoclonal antibody L6 in patients with non-small cell lung, colon, and breast cancer
-
[21] Goodman, G.E., Hellstrom, I., Yelton, D.E. et al. (1993) Phase I trial of chimeric (human-mouse) monoclonal antibody L6 in patients with non-small cell lung, colon, and breast cancer. Cancer Immunol. Immunother. 36, 267-273.
-
(1993)
Cancer Immunol. Immunother.
, vol.36
, pp. 267-273
-
-
Goodman, G.E.1
Hellstrom, I.2
Yelton, D.E.3
-
22
-
-
0023680837
-
Preclinical studies on the pharmacokinetic properties of human monoclonal antibodies to colorectal cancer and their use for detection of tumours
-
[22] McCabe, R.P., Peters, L.C., Haspel, M.V., Pomato, N., Carrasquillo, J.A. and Hanna, M.G. Jr. (1988) Preclinical studies on the pharmacokinetic properties of human monoclonal antibodies to colorectal cancer and their use for detection of tumours. Cancer Res. 48, 4348-4353.
-
(1988)
Cancer Res.
, vol.48
, pp. 4348-4353
-
-
McCabe, R.P.1
Peters, L.C.2
Haspel, M.V.3
Pomato, N.4
Carrasquillo, J.A.5
Hanna M.G., Jr.6
-
23
-
-
0026327427
-
Human IgM monoclonal antibody 16.88: Pharmacokinetics and immunogenicity in colorectal cancer patients
-
[23] Haisma, H.J., Pinedo, H.M., Kessel, M.A.P. et al. (1991) Human IgM monoclonal antibody 16.88: pharmacokinetics and immunogenicity in colorectal cancer patients. J. Natl. Cancer Inst. 83, 1813-1819.
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 1813-1819
-
-
Haisma, H.J.1
Pinedo, H.M.2
Kessel, M.A.P.3
-
24
-
-
0025731301
-
A phase 1 study of repeated therapy with radiolabelled antibody to carcinoembryonic antigen using intermittent or continuous administration of cyclosporin A to suppress the immune response
-
[24] Ledermann, J.A., Begent, R.H.J., Massof, C., Kelly, A.M., Adam, T. and Bagshawe, K.D. (1991) A phase 1 study of repeated therapy with radiolabelled antibody to carcinoembryonic antigen using intermittent or continuous administration of cyclosporin A to suppress the immune response. Int. J. Cancer 47, 659-664.
-
(1991)
Int. J. Cancer
, vol.47
, pp. 659-664
-
-
Ledermann, J.A.1
Begent, R.H.J.2
Massof, C.3
Kelly, A.M.4
Adam, T.5
Bagshawe, K.D.6
-
25
-
-
0027285558
-
The use of monoclonal antibodies to achieve immunological tolerance
-
[25] Waldmann, H. and Cobbold, S. (1993) The use of monoclonal antibodies to achieve immunological tolerance. Immunol. Today 14(6), 247-251.
-
(1993)
Immunol. Today
, vol.14
, Issue.6
, pp. 247-251
-
-
Waldmann, H.1
Cobbold, S.2
-
26
-
-
0001144402
-
Characterisation of novel anthracycline prodrugs activated by human beta-glucuronidase for use in antibody-directed enzyme prodrug therapy
-
[26] Houba, P.H.J., Leenders, R.G.G., Boven, E., Scheeren, J.W., Pinedo, H.M. and Haisma, H.J. (1996) Characterisation of novel anthracycline prodrugs activated by human beta-glucuronidase for use in antibody-directed enzyme prodrug therapy. Biochem. Pharmacol. 52(3), 455-463.
-
(1996)
Biochem. Pharmacol.
, vol.52
, Issue.3
, pp. 455-463
-
-
Houba, P.H.J.1
Leenders, R.G.G.2
Boven, E.3
Scheeren, J.W.4
Pinedo, H.M.5
Haisma, H.J.6
-
27
-
-
0026569992
-
Molecular and functional characteristics of a fusion protein suited for tumour specific prodrug activation
-
[27] Bosslet, K., Czech, J., Lorenz, P., Sedlacek, H.H., Schuermann, M. and Seeman, G. (1992) Molecular and functional characteristics of a fusion protein suited for tumour specific prodrug activation. Br. J. Cancer 65, 234-238.
-
(1992)
Br. J. Cancer
, vol.65
, pp. 234-238
-
-
Bosslet, K.1
Czech, J.2
Lorenz, P.3
Sedlacek, H.H.4
Schuermann, M.5
Seeman, G.6
-
28
-
-
0028348376
-
Tumour selective prodrug activation by fusion protein mediated catalysis
-
[28] Bosslet, K., Czech, J. and Hoffman, D. (1994) Tumour selective prodrug activation by fusion protein mediated catalysis. Cancer Res. 54(8), 2151-2159.
-
(1994)
Cancer Res.
, vol.54
, Issue.8
, pp. 2151-2159
-
-
Bosslet, K.1
Czech, J.2
Hoffman, D.3
-
29
-
-
0029162562
-
Comprehensive pharmacokinetics of a humanised antibody and analysis of residual antiidiotypic responses
-
[29] Stephens, S., Emtage, S., Vetterlein, O. et al. (1995) Comprehensive pharmacokinetics of a humanised antibody and analysis of residual antiidiotypic responses. Immunology 85(4), 668-674.
-
(1995)
Immunology
, vol.85
, Issue.4
, pp. 668-674
-
-
Stephens, S.1
Emtage, S.2
Vetterlein, O.3
-
30
-
-
0030584783
-
Humanisation and molecular modeling of the anti-CD4 monoclonal antibody, OKT4a
-
[30] Pulito, V.L., Roberts, VA., Adair, J.R. et al. (1996) Humanisation and molecular modeling of the anti-CD4 monoclonal antibody, OKT4A. J. Immunol. 156(8), 2840-2850.
-
(1996)
J. Immunol.
, vol.156
, Issue.8
, pp. 2840-2850
-
-
Pulito, V.L.1
Roberts, V.A.2
Adair, J.R.3
-
31
-
-
0028056086
-
Possible consequences of human-antibody responses on the biodistribution of fragments of human, humanised or chimeric monoclonal antibodies - A note of caution
-
[31] Pimm, M.V. (1994) Possible consequences of human-antibody responses on the biodistribution of fragments of human, humanised or chimeric monoclonal antibodies - A note of caution. Life Sci. 55(2) PL45-PL49.
-
(1994)
Life Sci.
, vol.55
, Issue.2
-
-
Pimm, M.V.1
-
32
-
-
0028922605
-
Design of a genetic immunotoxin to eliminate toxin immunogenicity
-
[32] Chen, S.Y., Zani, C., Khouri, Y. and Marasco, W.A. (1995) Design of a genetic immunotoxin to eliminate toxin immunogenicity. Gene Ther. 2(2), 116-123.
-
(1995)
Gene Ther.
, vol.2
, Issue.2
, pp. 116-123
-
-
Chen, S.Y.1
Zani, C.2
Khouri, Y.3
Marasco, W.A.4
-
33
-
-
0023261356
-
FK506, a novel immunosuppressant isolated from a streptomyces. II. Immunosuppressive effect of FK506 in vitro
-
[33] Kino, T., Hatanaka, H., Miyata, S., Inamura, N. et al. (1987) FK506, a novel immunosuppressant isolated from a streptomyces. II. Immunosuppressive effect of FK506 in vitro. J. Antibiot. (Tokyo) 40, 1256-1265.
-
(1987)
J. Antibiot. (Tokyo)
, vol.40
, pp. 1256-1265
-
-
Kino, T.1
Hatanaka, H.2
Miyata, S.3
Inamura, N.4
-
34
-
-
0025902276
-
Preclinical evaluation of a new potent immunosuppressive agent, rapamycin
-
[34] Kahan, B.D., Chang, J.Y. and Sehgal, S.N. (1991) Preclinical evaluation of a new potent immunosuppressive agent, rapamycin. Transplantation 52, 185-191.
-
(1991)
Transplantation
, vol.52
, pp. 185-191
-
-
Kahan, B.D.1
Chang, J.Y.2
Sehgal, S.N.3
-
35
-
-
0025875138
-
Immunosuppressive effects of the morpholinoethyl ester of mycophenolic acid (RS-61443) in rat and nonhuman primate recipient of heart allografts
-
[35] Morris, R.E., Wang, J. and Blum, J.R. (1991) Immunosuppressive effects of the morpholinoethyl ester of mycophenolic acid (RS-61443) in rat and nonhuman primate recipient of heart allografts. Transplant. Proc. 23(suppl. 2), 19-25.
-
(1991)
Transplant. Proc.
, vol.23
, Issue.SUPPL. 2
, pp. 19-25
-
-
Morris, R.E.1
Wang, J.2
Blum, J.R.3
-
36
-
-
0027287575
-
Experience with mycophenolate mofetil (RS61443) in renal transplantation at a single center
-
[36] Deierhoi, M.H., Kauffman, R.S., Hudson, S.L. et al. (1993) Experience with mycophenolate mofetil (RS61443) in renal transplantation at a single center. Ann. Surg. 217(5) 476-484.
-
(1993)
Ann. Surg.
, vol.217
, Issue.5
, pp. 476-484
-
-
Deierhoi, M.H.1
Kauffman, R.S.2
Hudson, S.L.3
-
37
-
-
0027732959
-
New small molecule immunosuppressants for transplantation: Review of essential concepts
-
S275-S286
-
[37] Morris, R.E. (1993) New small molecule immunosuppressants for transplantation: Review of essential concepts. J. Heart Lung Transplant. 12(6)II, S275-S286.
-
(1993)
J. Heart Lung Transplant.
, vol.12
, Issue.6
-
-
Morris, R.E.1
-
38
-
-
0025156975
-
Deoxyspergualin directly suppresses antibody formation in vivo and in vitro
-
[38] Fujii, H., Takada, T., Nemoto, K. et al. (1987) Deoxyspergualin directly suppresses antibody formation in vivo and in vitro. J. Antibiot. 43, 213-219.
-
(1987)
J. Antibiot.
, vol.43
, pp. 213-219
-
-
Fujii, H.1
Takada, T.2
Nemoto, K.3
-
39
-
-
0029020550
-
Phase I clinical and pharmacological study of suppression of human antimouse antibody response to monoclonal antibody l6 by deoxyspergualin
-
[39] Dhingra, K., Fritsche, H., Murray, J.L., Lobuglio, A.F., Khazaeli, M.B. et al. (1995) Phase I clinical and pharmacological study of suppression of human antimouse antibody response to monoclonal antibody L6 by deoxyspergualin. Cancer Res. 55, 3060-3067.
-
(1995)
Cancer Res.
, vol.55
, pp. 3060-3067
-
-
Dhingra, K.1
Fritsche, H.2
Murray, J.L.3
Lobuglio, A.F.4
Khazaeli, M.B.5
-
40
-
-
0023253842
-
Tolerogenic polyethylene glycol derivatives of xenogenic monoclonal immunoglobulins
-
[40] Wilkinson, I., Jackson, C.J.S., Lang, G.M., Holford-Strevens, V. and Sehon, A.H. (1987) Tolerogenic polyethylene glycol derivatives of xenogenic monoclonal immunoglobulins. Immunol. Lett. 15, 17-22.
-
(1987)
Immunol. Lett.
, vol.15
, pp. 17-22
-
-
Wilkinson, I.1
Jackson, C.J.S.2
Lang, G.M.3
Holford-Strevens, V.4
Sehon, A.H.5
-
41
-
-
0024252555
-
Tolerogenic conjugates of xenogenic monoclonal antibodies with monomethoxypolyethylene glycol. I. Induction of longlasting tolerance to xenogenic monoclonal antibodies
-
[41] Maiti, P.K., Lang, G.M. and Sehon, A.H. (1988) Tolerogenic conjugates of xenogenic monoclonal antibodies with monomethoxypolyethylene glycol. I. Induction of longlasting tolerance to xenogenic monoclonal antibodies. Int. J. Cancer suppl.(3), 17-22.
-
(1988)
Int. J. Cancer Suppl.
, Issue.3
, pp. 17-22
-
-
Maiti, P.K.1
Lang, G.M.2
Sehon, A.H.3
-
42
-
-
0017388651
-
Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase
-
[42] Abuchowski, A., McCoy, J.R., Palczuk, N.C., van Es, T. and Davis, F.F. (1977) Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. J. Biol. Chem. 252, 3582-3586.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 3582-3586
-
-
Abuchowski, A.1
McCoy, J.R.2
Palczuk, N.C.3
Van Es, T.4
Davis, F.F.5
-
43
-
-
0019461927
-
Reduction in immunogenicity and clearance rate of Escherichia coli L-asparaginase by modification with monomethoxypolyethylene glycol
-
[43] Kamisaki, Y., Wada, H., Yagura, T., Matsushima, A. and Inada, Y. (1981) Reduction in immunogenicity and clearance rate of Escherichia coli L-asparaginase by modification with monomethoxypolyethylene glycol. J. Pharmacol. Exp. Ther. 216, 410-414.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.216
, pp. 410-414
-
-
Kamisaki, Y.1
Wada, H.2
Yagura, T.3
Matsushima, A.4
Inada, Y.5
-
44
-
-
0028979995
-
t-Asparaginase modified by Poly(ethylene Glycol) derivative with a comb-shaped form-Antitumor-activity and induction of immune tolerance
-
[44] Sekine, T., Kodera, Y., Saito, T., Hiroto, M., Matsushima, A., Nishimura, H. and Inada, Y. (1995) t-Asparaginase modified by Poly(ethylene Glycol) derivative with a comb-shaped form-Antitumor-activity and induction of immune tolerance. Biomed. Res. 16(2), 121-123.
-
(1995)
Biomed. Res.
, vol.16
, Issue.2
, pp. 121-123
-
-
Sekine, T.1
Kodera, Y.2
Saito, T.3
Hiroto, M.4
Matsushima, A.5
Nishimura, H.6
Inada, Y.7
-
45
-
-
0021263381
-
Induction of tolerance in mice by uricase and monomethoxypolyethylene glycol-modified uricase
-
[45] Savoca, K.V., Davis, F.F. and Palezuk, N.C. (1984) Induction of tolerance in mice by uricase and monomethoxypolyethylene glycol-modified uricase. Int. Arch. Allergy Appl. Immunol. 75, 58-67.
-
(1984)
Int. Arch. Allergy Appl. Immunol.
, vol.75
, pp. 58-67
-
-
Savoca, K.V.1
Davis, F.F.2
Palezuk, N.C.3
-
46
-
-
0026659050
-
IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency
-
[46] Chaffee, S., Mary, A., Stiehm, E.R., Girault, D., Fischer, A. and Hershfield, M.S. (1992) IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency. J. Clin. Invest. 89, 1643-1651.
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 1643-1651
-
-
Chaffee, S.1
Mary, A.2
Stiehm, E.R.3
Girault, D.4
Fischer, A.5
Hershfield, M.S.6
-
47
-
-
0030042161
-
Polyethylene glycol modification of a galactosylated streptavidin clearing agent: Effects on immunogenicity and clearance of a biotinylated anti-tumour antibody
-
[47] Marshall, D., Pedley, R.B., Boden, J.A., Boden, R., Melton, R.G. and Begent, R.H.J. (1996) Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibody. Br. J. Cancer 73, 565-572.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 565-572
-
-
Marshall, D.1
Pedley, R.B.2
Boden, J.A.3
Boden, R.4
Melton, R.G.5
Begent, R.H.J.6
-
48
-
-
0029993066
-
Altered biodistribution of an antibody-enzyme conjugate modified with polyethylene glycol
-
[48] Eno-Amooquaye, E.A., Searle, F., Boden, J.A., Sharma, S.K. and Burke, P.J. (1996) Altered biodistribution of an antibody-enzyme conjugate modified with polyethylene glycol. Br. J. Cancer 73, 1323-1327.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 1323-1327
-
-
Eno-Amooquaye, E.A.1
Searle, F.2
Boden, J.A.3
Sharma, S.K.4
Burke, P.J.5
-
49
-
-
0342473740
-
Human anti-idiotype antibodies in cancer patients: Is the modulation of the immune response beneficial for the patient?
-
[49] Koprowski, H., Herlyn, D., Lubeck, M., DeFreitas, E. and Sears, H.F. (1984) Human anti-idiotype antibodies in cancer patients: is the modulation of the immune response beneficial for the patient? Proc. Natl. Acad. Sci. USA 81, 216-219.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 216-219
-
-
Koprowski, H.1
Herlyn, D.2
Lubeck, M.3
DeFreitas, E.4
Sears, H.F.5
-
50
-
-
0026351808
-
Human response against NP-4, a mouse antibody to carcinoembryonic antigen: Human anti-idiotype antibodies mimic an epitope on the tumour antigen
-
[50] Losman, M.J., Hansen, H.J., Sharkey, R.M., Goldenberg, D.M. and Monestier, M. (1991) Human response against NP-4, a mouse antibody to carcinoembryonic antigen: human anti-idiotype antibodies mimic an epitope on the tumour antigen. Proc. Natl. Acad. Sci. USA 88, 3421-3425.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3421-3425
-
-
Losman, M.J.1
Hansen, H.J.2
Sharkey, R.M.3
Goldenberg, D.M.4
Monestier, M.5
-
51
-
-
0026584248
-
Human high molecular weight melanoma associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: Induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma
-
[51] Mittleman, A., Chen, Z.J., Yang, H. et al. (1992) Human high molecular weight melanoma associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma. Proc. Natl. Acad. Sci. USA 89, 466-470.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 466-470
-
-
Mittleman, A.1
Chen, Z.J.2
Yang, H.3
-
52
-
-
0028013239
-
Activating anti-idiotypic human anti-mouse antibodies for immunotherapy of ovarian carcinoma
-
[52] Baum, R.P., Niesen, A., Hertel, A. et al. (1994) Activating anti-idiotypic human anti-mouse antibodies for immunotherapy of ovarian carcinoma. Cancer 73, 1121-1125.
-
(1994)
Cancer
, vol.73
, pp. 1121-1125
-
-
Baum, R.P.1
Niesen, A.2
Hertel, A.3
-
53
-
-
0028217536
-
Activation of cellular immunity after intracavitary monoclonal antibody therapy of ovarian cancer
-
[53] Kosmas, C., Epenetos, A.A. and Courtenayluck, N.S. (1994) Activation of cellular immunity after intracavitary monoclonal antibody therapy of ovarian cancer. Cancer 73, 3000-3010.
-
(1994)
Cancer
, vol.73
, pp. 3000-3010
-
-
Kosmas, C.1
Epenetos, A.A.2
Courtenayluck, N.S.3
-
54
-
-
0029671436
-
Toward antibody-directed abzyme prodrug therapy, ADAPT-carbamate prodrug activation by a catalytic antibody and its in-vitro application to human tumor-cell killing
-
[54] Wentworth, P., Datta, A., Blakey, D., Boyle, T., Partridge, L.J. and Blackburn, G.M. (1996) Toward antibody-directed abzyme prodrug therapy, ADAPT-carbamate prodrug activation by a catalytic antibody and its in-vitro application to human tumor-cell killing. Proc. Natl. Acad. Sci. USA 93(2), 799-803.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, Issue.2
, pp. 799-803
-
-
Wentworth, P.1
Datta, A.2
Blakey, D.3
Boyle, T.4
Partridge, L.J.5
Blackburn, G.M.6
-
55
-
-
0029967694
-
In-vivo immunosuppression by targeting a novel protease receptor
-
[55] Duchosal, M.A., Rothermel, A.L., McConahey, P.J., Dixon, F.J. and Altieri, D.C. (1996) In-vivo immunosuppression by targeting a novel protease receptor. Nature 380, 352-356.
-
(1996)
Nature
, vol.380
, pp. 352-356
-
-
Duchosal, M.A.1
Rothermel, A.L.2
McConahey, P.J.3
Dixon, F.J.4
Altieri, D.C.5
|