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Volumn 1288, Issue 2, 1996, Pages

DCC: Is there a connection between tumorigenesis and cell guidance molecules?

Author keywords

[No Author keywords available]

Indexed keywords

COLON CANCER; HUMAN; PRIORITY JOURNAL; REVIEW; TUMOR SUPPRESSOR GENE;

EID: 0030577117     PISSN: 0304419X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-419X(96)00023-6     Document Type: Short Survey
Times cited : (64)

References (52)
  • 1
    • 0026010995 scopus 로고
    • Molecular themes in oncogenesis
    • [1] Bishop, J.M. (1991) Molecular themes in oncogenesis. Cell 64, 235.
    • (1991) Cell , vol.64 , pp. 235
    • Bishop, J.M.1
  • 2
    • 0027970838 scopus 로고
    • Chromosomal translocation in human cancer
    • [2] Rabbitts, T.H. (1994) Chromosomal translocation in human cancer. Nature 372, 143.
    • (1994) Nature , vol.372 , pp. 143
    • Rabbitts, T.H.1
  • 3
    • 0026337295 scopus 로고
    • Tumor suppressor gene
    • [3] Weinberg, R.A. (1991) Tumor suppressor gene. Science 254, 1138.
    • (1991) Science , vol.254 , pp. 1138
    • Weinberg, R.A.1
  • 4
    • 0027504088 scopus 로고
    • Antioncogenes and human cancer
    • [4] Knudson, A.G. (1993) Antioncogenes and human cancer. Proc. Natl. Acad. Sci. USA 90, 10914-10921.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10914-10921
    • Knudson, A.G.1
  • 5
    • 0028564949 scopus 로고
    • Mismatch repair, genetic stability, and cancer
    • [5] Modrich, P. (1994) Mismatch repair, genetic stability, and cancer. Science 266, 1959.
    • (1994) Science , vol.266 , pp. 1959
    • Modrich, P.1
  • 6
    • 0029089259 scopus 로고
    • Hereditary nonpolyposis colorectal cancer: The syndrome, the genes, and historical perspectives
    • [6] Marra, G. and Boland, C.R. (1995) Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. J. Natl. Cancer Inst. 87, 1114-1125.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1114-1125
    • Marra, G.1    Boland, C.R.2
  • 8
    • 0028959978 scopus 로고
    • DCC: Linking tumor suppressor genes and altered cell surface interactions in cancer?
    • [8] Cho, K.R. and Fearon, E.R. (1995) DCC: linking tumor suppressor genes and altered cell surface interactions in cancer? Curr. Opin. Genet. Dev. 5, 72-78.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 72-78
    • Cho, K.R.1    Fearon, E.R.2
  • 9
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • [9] Fearon, E.R. and Vogelstein, B. (1990) A genetic model for colorectal tumorigenesis. Cell 61, 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 12
    • 0027474820 scopus 로고
    • Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma
    • [12] Ookawa, K., Sakamoto, M., Hirohashi, S., Yoshida, Y., Sugimura, T., Terada, M. and Yokota, J. (1993) Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma. Int. J. Cancer 53, 382-387.
    • (1993) Int. J. Cancer , vol.53 , pp. 382-387
    • Ookawa, K.1    Sakamoto, M.2    Hirohashi, S.3    Yoshida, Y.4    Sugimura, T.5    Terada, M.6    Yokota, J.7
  • 14
    • 0027934722 scopus 로고
    • Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues
    • [14] Reale, M.A., Hu, G., Zafar, A.L., Getzenberg, R.H., Levine, S.M. and Fearon, E.R. (1994) Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues. Cancer Res. 54, 4493-4501.
    • (1994) Cancer Res. , vol.54 , pp. 4493-4501
    • Reale, M.A.1    Hu, G.2    Zafar, A.L.3    Getzenberg, R.H.4    Levine, S.M.5    Fearon, E.R.6
  • 18
    • 0028228920 scopus 로고
    • The DCC gene product in cellular differentiation and colorectal tumorigenesis
    • [18] Hedrick, L., Cho, K.R., Fearon, E.R., Wu, T.C., Kinzler, K.W. and Vogelstein, B. (1994) The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes Dev. 8, 1174-1183.
    • (1994) Genes Dev. , vol.8 , pp. 1174-1183
    • Hedrick, L.1    Cho, K.R.2    Fearon, E.R.3    Wu, T.C.4    Kinzler, K.W.5    Vogelstein, B.6
  • 20
    • 0026653164 scopus 로고
    • Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma
    • [20] Hohne, M.W., Halatsch, M.E., Kahl, G.F. and Weinel, R.J. (1992) Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma. Cancer Res. 52, 2616-2619.
    • (1992) Cancer Res. , vol.52 , pp. 2616-2619
    • Hohne, M.W.1    Halatsch, M.E.2    Kahl, G.F.3    Weinel, R.J.4
  • 23
    • 0028340088 scopus 로고
    • Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and thier relation to metastasis
    • [23] Miyake, S., Nagai, K., Yoshino, K., Oto, M., Endo, M. and Yuasa, Y. (1994) Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and thier relation to metastasis. Cancer Res. 54, 3007-3010.
    • (1994) Cancer Res. , vol.54 , pp. 3007-3010
    • Miyake, S.1    Nagai, K.2    Yoshino, K.3    Oto, M.4    Endo, M.5    Yuasa, Y.6
  • 24
    • 0027156230 scopus 로고
    • Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas
    • [24] Gao, X., Honn, K., Grignon, D., Sakr, W. and Chen, Y. (1993) Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas. Cancer Res. 53, 2723-2727.
    • (1993) Cancer Res. , vol.53 , pp. 2723-2727
    • Gao, X.1    Honn, K.2    Grignon, D.3    Sakr, W.4    Chen, Y.5
  • 26
    • 0027968338 scopus 로고
    • Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder
    • [26] Brewster, S.F., Gingell, J.C., Browne, S. and Brown, K.W. (1994) Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder. Br. J. Cancer 70, 697-700.
    • (1994) Br. J. Cancer , vol.70 , pp. 697-700
    • Brewster, S.F.1    Gingell, J.C.2    Browne, S.3    Brown, K.W.4
  • 27
    • 0027280477 scopus 로고
    • Allele loss from 5q21 (APC/MCC) and 18q21 (DCC) and DCC mRNA expression in breast cancer
    • [27] Thompson, A.M., Morris, R.G., Wallace, M., Wyllie, A.H., Steel, C.M. and Carter, D.C. (1993) Allele loss from 5q21 (APC/MCC) and 18q21 (DCC) and DCC mRNA expression in breast cancer. Br. J. Cancer 68, 64-68.
    • (1993) Br. J. Cancer , vol.68 , pp. 64-68
    • Thompson, A.M.1    Morris, R.G.2    Wallace, M.3    Wyllie, A.H.4    Steel, C.M.5    Carter, D.C.6
  • 28
  • 30
    • 0029560435 scopus 로고
    • DCC expression is altered by multiple mechanisms in brain tumours
    • [30] Ekstrand, B.C., Mansfield, T.A., Bigner, S.H. and Fearon, E.R. (1995) DCC expression is altered by multiple mechanisms in brain tumours. Oncogene 11, 2393-2402.
    • (1995) Oncogene , vol.11 , pp. 2393-2402
    • Ekstrand, B.C.1    Mansfield, T.A.2    Bigner, S.H.3    Fearon, E.R.4
  • 31
    • 0027228509 scopus 로고
    • Alterations in the deleted in colorectal carcinoma gene in human primary leukemias
    • [31] Miyake, K., Inokuchi, K., Dan, K. and Nomura, T. (1993) Alterations in the deleted in colorectal carcinoma gene in human primary leukemias. Blood 82, 927-930.
    • (1993) Blood , vol.82 , pp. 927-930
    • Miyake, K.1    Inokuchi, K.2    Dan, K.3    Nomura, T.4
  • 32
    • 0027322884 scopus 로고
    • DCC tumor suppressor gene is inactivated in hematologic malignancies showing monsomy 18
    • [32] Porfiri, E., Secker-Walker, L., Hoffbrand, A. and Hancock, J. (1993) DCC tumor suppressor gene is inactivated in hematologic malignancies showing monsomy 18. Blood 81, 2696-2701.
    • (1993) Blood , vol.81 , pp. 2696-2701
    • Porfiri, E.1    Secker-Walker, L.2    Hoffbrand, A.3    Hancock, J.4
  • 33
    • 0027381076 scopus 로고
    • Expression of the DCC gene in myelodysplastic syndromes and overt leukemia
    • [33] Miyake, K., Inokuchi, K., Dan, K. and Nomura, T. (1993) Expression of the DCC gene in myelodysplastic syndromes and overt leukemia. Leukemia Res. 17, 785-788.
    • (1993) Leukemia Res. , vol.17 , pp. 785-788
    • Miyake, K.1    Inokuchi, K.2    Dan, K.3    Nomura, T.4
  • 37
    • 0025980976 scopus 로고
    • Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18
    • [37] Tanaka, K., Oshimura, M., Kikuchi, R., Seki, M., Hayashi, T. and Miyaki, M. (1991) Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18. Nature 349, 340-342.
    • (1991) Nature , vol.349 , pp. 340-342
    • Tanaka, K.1    Oshimura, M.2    Kikuchi, R.3    Seki, M.4    Hayashi, T.5    Miyaki, M.6
  • 38
    • 0029027344 scopus 로고
    • The DCC gene suppresses the malignant phenotype of transformed human epithelial cells
    • [38] Klingelhutz, A.J., Hedrick, L., Cho, K.R., McDougall, J.K. (1995) The DCC gene suppresses the malignant phenotype of transformed human epithelial cells. Oncogene 10, 1581-1586.
    • (1995) Oncogene , vol.10 , pp. 1581-1586
    • Klingelhutz, A.J.1    Hedrick, L.2    Cho, K.R.3    McDougall, J.K.4
  • 40
    • 0028025737 scopus 로고
    • c DCC (chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction
    • [40] Chuong, C.M., Jiang, T.X., Yin, E. and Widelitz, R.B. (1994) c DCC (chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction. Dev. Biol. 164, 383-397.
    • (1994) Dev. Biol. , vol.164 , pp. 383-397
    • Chuong, C.M.1    Jiang, T.X.2    Yin, E.3    Widelitz, R.B.4
  • 41
    • 0028582004 scopus 로고
    • Expression of a homologue of the deleted in colorectal cancer (DCC) gene in the nervous system of developing Xenopus embryos
    • [41] Pierceall, W.E., Reale, M.A., Candia, A.F., Wright, C.V.E, Cho, K.R. and Fearon, E.R. (1994) Expression of a homologue of the deleted in colorectal cancer (DCC) gene in the nervous system of developing Xenopus embryos. Dev. Biol. 166, 654-665.
    • (1994) Dev. Biol. , vol.166 , pp. 654-665
    • Pierceall, W.E.1    Reale, M.A.2    Candia, A.F.3    Wright, C.V.E.4    Cho, K.R.5    Fearon, E.R.6
  • 42
    • 0029563119 scopus 로고
    • Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo
    • [42] Cooper, H.M., Armes, P., Britto, J., Gad, J. and Wilks, A.F. (1995) Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo. Oncogene 11, 2243-2254.
    • (1995) Oncogene , vol.11 , pp. 2243-2254
    • Cooper, H.M.1    Armes, P.2    Britto, J.3    Gad, J.4    Wilks, A.F.5
  • 43
    • 0026924204 scopus 로고
    • Persistent expression of the tumor suppressor gene DCC is essential for neuronal differentiation
    • [43] Lawlor, K. and Narayanan, R. (1992) Persistent expression of the tumor suppressor gene DCC is essential for neuronal differentiation. Cell Growth Differ. 3, 609-616.
    • (1992) Cell Growth Differ. , vol.3 , pp. 609-616
    • Lawlor, K.1    Narayanan, R.2
  • 44
    • 0028350796 scopus 로고
    • NIH3T3 cells expressing the deleted in colorectal cancer tumor suppressor gene product stimulate neurite outgrowth in rat PC12 pheochromocytoma cells
    • [44] Pierceall, W.E., Cho, K.R., Getzenberg, R.H., Reale, M.A., Hedrick, L., Vogelstein, B. and Fearon, E.R. (1994) NIH3T3 cells expressing the deleted in colorectal cancer tumor suppressor gene product stimulate neurite outgrowth in rat PC12 pheochromocytoma cells. J. Cell. Biol. 124, 1017-1027.
    • (1994) J. Cell. Biol. , vol.124 , pp. 1017-1027
    • Pierceall, W.E.1    Cho, K.R.2    Getzenberg, R.H.3    Reale, M.A.4    Hedrick, L.5    Vogelstein, B.6    Fearon, E.R.7
  • 45
    • 0028606322 scopus 로고
    • Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation is closely related to the human tumor suppressor molecule deleted in colorectal cancer
    • [45] Vielmetter, J., Kayyem, J.F., Roman, J.M. and Dreyer, W.J. (1994) Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation is closely related to the human tumor suppressor molecule deleted in colorectal cancer. J. Cell Biol. 127, 2009-2020.
    • (1994) J. Cell Biol. , vol.127 , pp. 2009-2020
    • Vielmetter, J.1    Kayyem, J.F.2    Roman, J.M.3    Dreyer, W.J.4
  • 46
    • 0011836977 scopus 로고
    • unc-40 encodes a protein related to the human DCC (deleted in colorectal cancer) protein
    • [46] Chan, S., Su, M.-W., Culotti, J. and Hedgecock, E. (1995) unc-40 encodes a protein related to the human DCC (deleted in Colorectal Cancer) protein. Worm Breeder's Gazette 13, 48.
    • (1995) Worm Breeder's Gazette , vol.13 , pp. 48
    • Chan, S.1    Su, M.-W.2    Culotti, J.3    Hedgecock, E.4
  • 47
    • 0025332245 scopus 로고
    • The unc-5, unc-6, and unc-40 genes guide circumferential migration of pioneer axons and mesodermal cells on the epidermis of C. elegans
    • [47] Hedgecock, E.M., Culotti, J.G. and Hall, D.H. (1990) The unc-5, unc-6, and unc-40 genes guide circumferential migration of pioneer axons and mesodermal cells on the epidermis of C. elegans. Neuron 2, 61-85.
    • (1990) Neuron , vol.2 , pp. 61-85
    • Hedgecock, E.M.1    Culotti, J.G.2    Hall, D.H.3
  • 48
    • 0027941462 scopus 로고
    • Axon guidance mechanisms in Caenorhabditis elegans
    • [48] Cullotti, J.G. (1994) Axon guidance mechanisms in Caenorhabditis elegans. Curr. Opin. Genet. Dev. 4, 587-595.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 587-595
    • Cullotti, J.G.1
  • 49
    • 0026481173 scopus 로고
    • UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans
    • [49] Ishii, N., Wadsworth, W.G., Stern, B.D., Culotti, J.G. and Hedgecock, E.M. (1992) UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans. Neuron 9, 873-881.
    • (1992) Neuron , vol.9 , pp. 873-881
    • Ishii, N.1    Wadsworth, W.G.2    Stern, B.D.3    Culotti, J.G.4    Hedgecock, E.M.5
  • 50
    • 0028138219 scopus 로고
    • The netrins define a family of axon outgrowth-promoting proteins homologous to the C. elegans UNC-6
    • [50] Serafini, T., Kennedy, T.E., Galko, M.J., Mirzayan, C., Jessell, T.M., Tessier-Lavigne, M. (1994) The netrins define a family of axon outgrowth-promoting proteins homologous to the C. elegans UNC-6. Cell 78, 409-424.
    • (1994) Cell , vol.78 , pp. 409-424
    • Serafini, T.1    Kennedy, T.E.2    Galko, M.J.3    Mirzayan, C.4    Jessell, T.M.5    Tessier-Lavigne, M.6
  • 51
    • 0028061313 scopus 로고
    • Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord
    • [51] Kennedy, T.E., Serafini, T., De la Torre, J.R., Tessier-Lavigne, M. (1994) Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78, 425-435.
    • (1994) Cell , vol.78 , pp. 425-435
    • Kennedy, T.E.1    Serafini, T.2    De La Torre, J.R.3    Tessier-Lavigne, M.4
  • 52
    • 0028921152 scopus 로고
    • Guidance and induction of branch formation in developing axons by target-derived diffusible factors
    • [52] Kennedy, T.E., Tessier-Lavigne, M. (1995) Guidance and induction of branch formation in developing axons by target-derived diffusible factors. Curr. Opin. Neurobiol. 5, 83-90.
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 83-90
    • Kennedy, T.E.1    Tessier-Lavigne, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.