Extending double modulation: Combinatorial rules far identifying the modulations necessary for determining elasticities in metabolic pathways

Journal of Theoretical Biology

Volumn 182, Issue 3, 1996, Pages 361-369

  Giersch, Christoph ^a   Cornish Bowden, Athel ^b  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME;

ENZYME REGULATION; FEEDBACK SYSTEM; LINEAR SYSTEM; METABOLIC REGULATION; PRIORITY JOURNAL; REVIEW;

EID: 0030574084     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1996.0175     Document Type: Article

References (10)

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3. GIERSCH, C. (1988). Control analysis of metabolic pathways: A novel procedure for calculating control coefficients, and an additional theorem for branched pathways. J. theor. Biol. 134, 451-462.
4. GIERSCH, C. (1994). Determining elasticities from multiple measurements of steady-state flux rates and metabolite concentrations: Theory. J. theor. Biol. 169, 89-99.
5. GIERSCH, C. (1995). Determining elasticities from multiple measurements of flux rates and metabolite concentrations: Application of the multiple modulation method to a reconstituted pathway. Eur. J. Biochem. 227, 194-201.
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7. HOFMEYR, J-H. S., CORNISH-BOWDEN, A. & ROHWER, J. M. (1993). Taking enzyme kinetics out of control; putting control into regulation. Eur. J. Biochem. 212, 833-837.
8. KACSER, H. & BURNS, J. A. (1979). Molecular democracy: Who shares the controls? Biochem. Soc. Trans. 7, 1149-1160.
9. ROHWER, J. M., SCHUSTER, S. & WESTERHOFF, H. V. (1994). An invariance property of coresponse coefficients in modular metabolic control and regulation analysis. In: What is Controlling Life? (Gnaiger, E., Gellerich, F. N. & Wyss, M., eds) pp. 109-110. Innsbruck: Innsbruck University Press.
10. SMALL, J. R. (1988). Theoretical aspects of metabolic control. Ph.D. Thesis, Oxford Polytechnic, Oxford.