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and references cited therein
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(b) The estrogen receptor is tolerant of estrogens bearing sizable substituents at the 11β position: Pomper, M. G.; VanBrocklin, H.; Thieme, A. M.; Thomas, R. D.; Kiesewetter, D. O.; Carlson, K. E.; Mathias, C. J.; Welch, M. J.; Katzenellenbogen, J. A. J. Med. Chem. 1990, 33, 3143 and references cited therein.
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24
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0018770060
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(d) An extensive study of receptor binding and uterotrophic activity has shown that the affinity and potency of various centchroman analogs are quite sensitive to the nature of C-2 substituents: Durani, S.; Agarwal, A. K.; Saxena, R.; Setty, B. S.; Gupta, R. C.; Kole, P., I.; Ray, S.; Anand, N. J. Steroid Biochem. 1979, 11, 67.
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25
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Katzenellenbogen, B.S.5
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