메뉴 건너뛰기




Volumn 66, Issue 2, 1996, Pages 131-137

21-Aminosteroids block neutrophil infiltration and provide liver protection independent of NO2/-/NO3/- levels

Author keywords

[No Author keywords available]

Indexed keywords

21 AMINOSTEROID; 21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE; LAZAROID; LIVER ENZYME; MYELOPEROXIDASE; NITRATE; NITRITE;

EID: 0030515261     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1996.0384     Document Type: Article
Times cited : (14)

References (33)
  • 1
    • 0023184568 scopus 로고
    • Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation
    • 1. Braughler, J. M., Pregenzer, J. F., Chase, R. L., et al. Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation. J. Biol. Chem. 262: 1143, 1987.
    • (1987) J. Biol. Chem. , vol.262 , pp. 1143
    • Braughler, J.M.1    Pregenzer, J.F.2    Chase, R.L.3
  • 2
    • 85030282542 scopus 로고
    • Avances en el manejo de la lesión de isquemia/reperfusión, con referencia a los 21 aminoesteroides
    • 2. Tamara, J. A., Hernandez, M. C., Toledo-Pereyra, L. H., et al. Avances en el manejo de la lesión de isquemia/reperfusión, con referencia a los 21 aminoesteroides. Rev. Fac. Med. UNAM 33: 383, 1990.
    • (1990) Rev. Fac. Med. UNAM , vol.33 , pp. 383
    • Tamara, J.A.1    Hernandez, M.C.2    Toledo-Pereyra, L.H.3
  • 3
    • 0023885152 scopus 로고
    • Inhibition of arachidonic acid-induced vasogenic brain edema by the non-glucocorticoid 21-aminosteroid U74006F
    • 3. Hall, E. D., and Travis, M. A. Inhibition of arachidonic acid-induced vasogenic brain edema by the non-glucocorticoid 21-aminosteroid U74006F. Brain Res. 451: 350, 1988.
    • (1988) Brain Res. , vol.451 , pp. 350
    • Hall, E.D.1    Travis, M.A.2
  • 4
    • 0023772124 scopus 로고
    • 21-Aminosteroid reduces ion shifts and edema in the rat middle cerebral artery occlusion model of regional ischemia
    • 4. Young, W., Wojak, J. C., and DeCrescito, V. 21-Aminosteroid reduces ion shifts and edema in the rat middle cerebral artery occlusion model of regional ischemia. Stroke 19: 1013, 1988.
    • (1988) Stroke , vol.19 , pp. 1013
    • Young, W.1    Wojak, J.C.2    DeCrescito, V.3
  • 5
    • 0023785218 scopus 로고
    • 21-Aminosteroid lipid peroxidation inhibition U-74006F protects against cerebral ischemia in gerbils
    • 5. Hall, E. D., Pazzara, K. E., Braughler, J. M., et al. 21-Aminosteroid lipid peroxidation inhibition U-74006F protects against cerebral ischemia in gerbils. Stroke 19: 997, 1988.
    • (1988) Stroke , vol.19 , pp. 997
    • Hall, E.D.1    Pazzara, K.E.2    Braughler, J.M.3
  • 6
    • 0024697075 scopus 로고
    • Attenuation of structural and functional damage from acute renal ischemia by the 21-amino steroid U74006F in rats
    • 6. Podrazik, R. M., Obedian, R. S., Remick, D. G., et al. Attenuation of structural and functional damage from acute renal ischemia by the 21-amino steroid U74006F in rats. Curr. Surg. 46: 287, 1989.
    • (1989) Curr. Surg. , vol.46 , pp. 287
    • Podrazik, R.M.1    Obedian, R.S.2    Remick, D.G.3
  • 7
    • 0025129099 scopus 로고
    • Effects of U74006F, a novel inhibitor of lipid peroxidation, in stunned reperfused canine myocardium
    • 7. Holzgrefe, H. H., Buchanan, L. V., and Gibson, J. K. Effects of U74006F, a novel inhibitor of lipid peroxidation, in stunned reperfused canine myocardium. J. Cardiovasc. Pharmacol. 15: 239, 1990.
    • (1990) J. Cardiovasc. Pharmacol. , vol.15 , pp. 239
    • Holzgrefe, H.H.1    Buchanan, L.V.2    Gibson, J.K.3
  • 8
    • 85030288927 scopus 로고
    • Acute mesenteric small bowel ischemia in the rat: Effect of the 21-aminosteroid U-74006F
    • 8. Hernández, M. C., Tamara, J. A., Toledo-Pereyra, et al. Acute mesenteric small bowel ischemia in the rat: Effect of the 21-aminosteroid U-74006F. Res. Surg. 3: 10, 1991.
    • (1991) Res. Surg. , vol.3 , pp. 10
    • Hernández, M.C.1    Tamara, J.A.2    Toledo-Pereyra3
  • 9
    • 0025841791 scopus 로고
    • Effect of a 21-aminosteroid and or adenosine in the ischemic rat liver
    • 9. Hernández, M. C., Walters, W., and Toledo-Pereyra, L. H. Effect of a 21-aminosteroid and or adenosine in the ischemic rat liver. Transplant Proc. 2428, 1991.
    • (1991) Transplant Proc. , pp. 2428
    • Hernández, M.C.1    Walters, W.2    Toledo-Pereyra, L.H.3
  • 10
    • 0025850888 scopus 로고
    • U74006F, a novel 21-aminosteroid, inhibits in vivo lipid peroxidation but fails to limit infarct size in a canine model of myocardial ischemia reperfusion
    • 10. Ovize, M., Lorgeril, M., Ovize, A., et al. U74006F, a novel 21-aminosteroid, inhibits in vivo lipid peroxidation but fails to limit infarct size in a canine model of myocardial ischemia reperfusion. Am. Heart J. 122: 681, 1991.
    • (1991) Am. Heart J. , vol.122 , pp. 681
    • Ovize, M.1    Lorgeril, M.2    Ovize, A.3
  • 11
    • 0026486834 scopus 로고
    • Evaluation of intestinal villus height in rats after ischemia and reperfusion by administration of superoxide dismutase, polyethylene glycol-conjugated superoxide dismutase, and two 21-aminosteroids
    • 11. Stone, W. C., Bjorling, D. E., Southard, J. H., et al. Evaluation of intestinal villus height in rats after ischemia and reperfusion by administration of superoxide dismutase, polyethylene glycol-conjugated superoxide dismutase, and two 21-aminosteroids. Am. J. Vet. Res. 53: 2153, 1992.
    • (1992) Am. J. Vet. Res. , vol.53 , pp. 2153
    • Stone, W.C.1    Bjorling, D.E.2    Southard, J.H.3
  • 12
    • 0027278364 scopus 로고
    • Attenuation of renal reperfusion injury in rats by the 21-aminosteroid U74006F
    • 12. Stanley, J. J., Goldblum, J. R., Frank, T. S., et al. Attenuation of renal reperfusion injury in rats by the 21-aminosteroid U74006F. J. Vasc. Surg. 685, 1993.
    • (1993) J. Vasc. Surg. , vol.685
    • Stanley, J.J.1    Goldblum, J.R.2    Frank, T.S.3
  • 13
    • 0026708706 scopus 로고
    • Improvement of endothelial cell viability at 4°C by addition of lazaroid U74500A to preservation solutions
    • 13. Killinger, W. A., Dorofi, D. B., Keagy, B. A., et al. Improvement of endothelial cell viability at 4°C by addition of lazaroid U74500A to preservation solutions. Transplantation 53: 983, 1992.
    • (1992) Transplantation , vol.53 , pp. 983
    • Killinger, W.A.1    Dorofi, D.B.2    Keagy, B.A.3
  • 14
    • 0026452988 scopus 로고
    • Lazaroid U74500A as an additive to University of Wisconsin solution for pulmonary grafts in the rat transplant model
    • 14. Aeba, R., Killinger, W. A., Keenan, R. J., et al. Lazaroid U74500A as an additive to University of Wisconsin solution for pulmonary grafts in the rat transplant model. J. Thorac. Cardiovasc. Surg. 104: 1333, 1992.
    • (1992) J. Thorac. Cardiovasc. Surg. , vol.104 , pp. 1333
    • Aeba, R.1    Killinger, W.A.2    Keenan, R.J.3
  • 15
    • 0026730299 scopus 로고
    • Improved donor myocardial recovery with a new lazaroid lipid antiperoxidant in the isolated canine heart
    • 15. Hendry, P. J., Anstadt, M. P., Plunkett, M. D., et al. Improved donor myocardial recovery with a new lazaroid lipid antiperoxidant in the isolated canine heart. J. Heart Lung Transplant. 11: 636, 1992.
    • (1992) J. Heart Lung Transplant. , vol.11 , pp. 636
    • Hendry, P.J.1    Anstadt, M.P.2    Plunkett, M.D.3
  • 16
    • 0027264451 scopus 로고
    • Protective effects of the lazaroid U74500A and lidoflazine on liver preservation with UW solution
    • 16. Jacobsson, J., Sundberg, R., Rilo, H. L., et al. Protective effects of the lazaroid U74500A and lidoflazine on liver preservation with UW solution. Transplant. Int. 6: 281, 1993.
    • (1993) Transplant. Int. , vol.6 , pp. 281
    • Jacobsson, J.1    Sundberg, R.2    Rilo, H.L.3
  • 17
    • 0028141678 scopus 로고
    • Inhibition of neutrophil leukotriene generation by the 21-aminosteroid, U-74389F
    • 17. Gadaleta, D., Verma, M., and Davis, J. M. Inhibition of neutrophil leukotriene generation by the 21-aminosteroid, U-74389F. J. Surg. Res. 57: 233, 1994.
    • (1994) J. Surg. Res. , vol.57 , pp. 233
    • Gadaleta, D.1    Verma, M.2    Davis, J.M.3
  • 18
    • 0027499407 scopus 로고
    • Inhibition of tumor necrosis factor release from cultured rat Kupffer cells by agents that reduce graft failure from storage injury
    • 18. Currin, R. T., Reinstein, L. J., Lichtman, S. N., et al. Inhibition of tumor necrosis factor release from cultured rat Kupffer cells by agents that reduce graft failure from storage injury. Transplant. Proc. 25: 1631, 1993.
    • (1993) Transplant. Proc. , vol.25 , pp. 1631
    • Currin, R.T.1    Reinstein, L.J.2    Lichtman, S.N.3
  • 19
    • 0025221099 scopus 로고
    • Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages
    • 19. Di Rosa, M., Radomski, M., Carnuccio, R., et al. Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochem. Biophys. Res. Commun. 172: 1246, 1990.
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 1246
    • Di Rosa, M.1    Radomski, M.2    Carnuccio, R.3
  • 20
    • 0026751947 scopus 로고
    • The L-arginine: Nitric oxide pathway
    • 20. Moncada, S. The L-arginine: Nitric oxide pathway. Acta Physiol. Scand. 145: 201, 1992.
    • (1992) Acta Physiol. Scand. , vol.145 , pp. 201
    • Moncada, S.1
  • 21
    • 0027094198 scopus 로고
    • Physiopathologic advantages of portosystemic shunting for studies of total hepatic ischemia and reperfusion injury in the rat
    • 21. Suzuki, S., Toledo-Pereyra, L. H., Rodriguez, F. J., et al. Physiopathologic advantages of portosystemic shunting for studies of total hepatic ischemia and reperfusion injury in the rat. Transplantology 3: 96, 1992.
    • (1992) Transplantology , vol.3 , pp. 96
    • Suzuki, S.1    Toledo-Pereyra, L.H.2    Rodriguez, F.J.3
  • 22
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
    • 22. Bradley, P. P., Priebat, D. A., Christensen, R. D., et al. Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:206, 1982.
    • (1982) J. Invest. Dermatol. , vol.78 , pp. 206
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3
  • 23
    • 0021998590 scopus 로고
    • Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium
    • 23. Mullane, K. M., Kraemer, R., and Smith, B. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods 14: 157, 1985.
    • (1985) J. Pharmacol. Methods , vol.14 , pp. 157
    • Mullane, K.M.1    Kraemer, R.2    Smith, B.3
  • 24
    • 0028104129 scopus 로고
    • Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury
    • 24. Suzuki, S., Toledo-Pereyra, L. H., Rodriguez, F. J., et al. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. J. Surg. Res. 57: 253, 1994.
    • (1994) J. Surg. Res. , vol.57 , pp. 253
    • Suzuki, S.1    Toledo-Pereyra, L.H.2    Rodriguez, F.J.3
  • 25
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • 25. Kubes, P., Suzuki, M., and Granger, D. Nitric oxide: An endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA 88: 4651, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4651
    • Kubes, P.1    Suzuki, M.2    Granger, D.3
  • 26
    • 0028034751 scopus 로고
    • Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion
    • 26. Gauthier, T., Davenpeck, K., and Lefer, A. Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion. Am. J. Physiol. 269: G562, 1994.
    • (1994) Am. J. Physiol. , vol.269
    • Gauthier, T.1    Davenpeck, K.2    Lefer, A.3
  • 27
    • 0028923589 scopus 로고
    • Modulation of neutrophil infiltration through nitric oxide in the ischemic rat kidney
    • 27. Lopez-Neblina, F., Paez, A. J., and Toledo-Pereyra, L. H. Modulation of neutrophil infiltration through nitric oxide in the ischemic rat kidney. Transplant. Proc. 27: 1883, 1995.
    • (1995) Transplant. Proc. , vol.27 , pp. 1883
    • Lopez-Neblina, F.1    Paez, A.J.2    Toledo-Pereyra, L.H.3
  • 28
    • 0025221099 scopus 로고
    • Glucocorticoids inhibit the induction of Nitric Oxide Synthase in Macrophages
    • 28. DiRosa, M., Radomski, R., Carniccio, R., et al. Glucocorticoids inhibit the induction of Nitric Oxide Synthase in Macrophages. Biochem. Biophys. Res. Com. 172: 1246, 1990.
    • (1990) Biochem. Biophys. Res. Com. , vol.172 , pp. 1246
    • DiRosa, M.1    Radomski, R.2    Carniccio, R.3
  • 29
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • 29. Nathan, C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6: 3051, 1992.
    • (1992) FASEB J. , vol.6 , pp. 3051
    • Nathan, C.1
  • 30
    • 0028035106 scopus 로고
    • The high output nitric oxide pathway: Role and regulation
    • 30. Xie, Q., and Nathan, C. The high output nitric oxide pathway: Role and regulation. J-Leukocyte Biol. 56: 576, 1994.
    • (1994) J-Leukocyte Biol. , vol.56 , pp. 576
    • Xie, Q.1    Nathan, C.2
  • 32
    • 0030024352 scopus 로고    scopus 로고
    • Lazaroids for 48 hour canine liver preservation
    • 32. Todo, S., Hamada, N, Zhu, Y., et al. Lazaroids for 48 hour canine liver preservation. Transplantation 61: 189, 1996.
    • (1996) Transplantation , vol.61 , pp. 189
    • Todo, S.1    Hamada, N.2    Zhu, Y.3
  • 33
    • 0026713741 scopus 로고
    • Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia
    • 33. Jaeschke, H., Bautista, A. P., Spolarics, Z., et al. Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia. J. Leukocyte Biol. 52: 377, 1992.
    • (1992) J. Leukocyte Biol. , vol.52 , pp. 377
    • Jaeschke, H.1    Bautista, A.P.2    Spolarics, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.