Site-directed estrogen receptor antibodies stabilize 4-hydroxytamoxifen ligand, but not estradiol, and indicate ligand-specific differences in the recognition of estrogen response element DNA in vitro

Steroids

Volumn 61, Issue 5, 1996, Pages 278-289

  Klinge, Carolyn M ^a   Traish, Abdulmaged M ^b   Driscoll, Mark D ^a   Hilf, Russell ^a   Bambara, Robert A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

4 hydroxytamoxifen; Antibody; Antiestrogen; Estrogen receptor; Estrogen response element; Tamoxifen aziridine

Indexed keywords

4 HYDROXYTAMOXIFEN; ANTIESTROGEN; ESTRADIOL; ESTROGEN RECEPTOR; LIGAND; MONOCLONAL ANTIBODY; PLASMID DNA; POLYCLONAL ANTIBODY; RECEPTOR ANTIBODY; SYNTHETIC PEPTIDE; TAMOXIFEN AZIRIDINE;

ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CONFORMATION; CONSENSUS SEQUENCE; DISSOCIATION; DNA BINDING; HORMONE RESPONSIVE ELEMENT; RECEPTOR BINDING; STOICHIOMETRY;

ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; BASE SEQUENCE; CONSENSUS SEQUENCE; DNA; ESTRADIOL; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; RECEPTORS, ESTROGEN; TAMOXIFEN;

EID: 0029994081     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0039-128X(95)00219-G     Document Type: Article

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