Mechanisms of tolerance during treatment with nitroglycerin patches for 24 h

European Journal of Clinical Pharmacology

Volumn 51, Issue 3-4, 1996, Pages 227-230

  Klemsdal, T O ^a   Mundal, H H ^a   Gjesdal, K ^a  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

counterregulation; digital photoplethysmography; exercise test; nitrate; tolerance; transdermal

Indexed keywords

GLYCERYL TRINITRATE;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CLINICAL ARTICLE; DRUG MECHANISM; DRUG TOLERANCE; EXERCISE; HEADACHE; HEART RATE; HEMATOCRIT; HEMODYNAMICS; HUMAN; MALE; PLETHYSMOGRAPHY; PRIORITY JOURNAL; VASODILATATION; VERTIGO;

EID: 0030476046     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050188     Document Type: Article

References (25)

1. Parker JO, Fung HL (1984) Transdermal nitroglycerin in angina pectoris. Am J Cardiol 54:471-476
2. Cowan JC, Bourke JP, Reid DS, Julian DG (1987) Prevention of tolerance to nitroglycerin patches by overnight removal. Am J Cardiol 60:271-275
3. Steering Committee, Transdermal Nitroglycerin Cooperative Study (1991) Acute and chronic efficacy of continuous twenty-four-hour application of transdermal nitroglycerin. Am J Cardiol 68:1263-1273
4. Klemsdal TO, Gjesdal K (1992) The effect of transdermal nitroglycerin on exercise tolerance in relation to patch application time - a meta-analysis. Cardiovasc Drugs Ther 6:641-649
5. Mangione JN, Glasser SP (1994) Phenomenon of nitrate tolerance. Am Heart J 128:137-146
6. Fung HL (1993) Solving the mystery of nitrate tolerance. A new scent on the trail? Circulation 88:322-324
7. Klemsdal TO, Mundal HH, Rudberg N, Gjesdal K (1994) A new isosorbide dinitrate extended release formulation: Pharmacokinetic and clinical parameters in patients with stable angina pectoris. Eur J Clin Pharmacol 47:351-354
8. Lund F (1986) Digital pulse plethysmography in studies of the hemodynamic response to nitrates - A survey of recording methods and principles of analysis. Acta Pharmacol Toxicol 59 [Suppl VI]:79-96
9. Imhof PR, Ott B, Frankhauser P, Chu LC, Hodler J (1980) Difference in nitroglycerin dose-response in the venous and arterial beds. Eur J Clin Pharmacol 18:455-460
10. Bass A, Walden R, Hirshberg A, Schneiderman J (1989) Pharmacokinetic activity of nitrites evaluated by digital pulse volume recording. J Cardiovasc Surg 30:395-397
11. Klemsdal TO, Andersson TLG, Matz J, Ferns GAA, Gjesdal K, Änggård EE (1994) Vitamin E restores endothelium dependent vasodilation in cholesterol fed rabbits. In vivo measurements by photoplethysmography. Cardiovasc Res 28: 1397-1402
12. Sundberg S, Castrén M (1986) Drug- and temperature-induced changes in peripheral circulation measured by laser-Doppler flowmetry and digital-pulse plethysmography. Scan J Clin Lab Invest 46:359-365
13. Selke FW, Myers PR, Bates JN, Harrison DG (1990) Influence of vessel size on the sensitivity of porcine coronary microvessels to nitroglycerin. Am J Physiol 258 [Heart Circ Physiol 27]:H515-H520
14. Boesgaard S, Iversen H, Wroblevski H, Poulsen HE, Frandsen H, Kastrup J, Aldershvile J (1993) Altered vasodilatory profile of nitroglycerin during long-term infusion of N-acetylcysteine. Circulation 88:I-90 (Abstract)
15. Jeserich M, Münzel T, Pape L, Fischer C, Drexler H, Just H (1995) Absence of vascular tolerance in conductance vessels after 48 hours of intravenous nitroglycerin in patients with coronary artery disease J Am Coll Cardiol 26:50-56
16. Pizulli L, Zirbes M (1995) Sustained vasodilation of non-obstructed segments of epicardial arteries during a 48-h nitroglycerin infusion. Circulation 92:1-18 (Abstract)
17. Münzel T, Heitzer T, Kurz S, Harrison DG, Luhman C, Pape L, Olschewski M, Just H (1996) Dissociation of coronary vascular tolerance and neurohormonal adjustments during long-term nitroglycerin therapy in patients with stable coronary artery disease. J Am Coll Cardiol 27:297-303
18. Kai H, Yamamato H, Mitsuru N, Suzuki S, Yoshimura H, Tajimi T, Sugihara M, Kikuchi Y (1994) Effects of continuous intravenous infusion of isosorbide dinitrate on development of tolerance to vasodilating action in human epicardial coronary arteries. Am Heart J 128:230-236
19. Moreyra AE, Kostis JB (1989) Effect of cutaneous nitroglycerin patches on coronary artery diameter: issues concerning development of tolerance. J Am Coll Cardiol 13:428-433
20. Imhof PR, Rennwald D, Müller P, Howald H, Burkart F (1989) Circulatory counter-regulations induced by continuous administration of nitroglycerin. Methods Find Exp Clin Pharmacol 11:409-414
21. Muiesan ML, Agabiti-Rosei E, Romanelli G, Beschi M, Castellano M, Cefis M, Cerri B, Pollavini G, Muiesan G (1992) Transdermal nitroglycerin efficacy in patients with chronic stable angina pectoris as related to sympathetic and renin-angiotensin-aldosterone activity. Eur Heart J 13:15-21
22. Dupuis J, Lalonde G, Lemieux R, Rouleau JL (1990) Tolerance to intravenous nitroglycerin in patients with congestive heart failure: role of increased vascular volume, neurohumoral activation and lack of prevention with N-acetylcystein. J Am Coll Cardiol 16:923-931
23. Sussex BA, Campbell NRC, Raju MK, McKay DW (1994) The antianginal efficacy of isosorbide dinitrate therapy is maintained during diuretic treatment. Clin Pharmacol Ther 56:229-234
24. Mohanty N, Wasserman AG, Walker P, Katz RJ (1995) Prevention of nitroglycerin tolerance with diuretics. Am Heart J 130:522-527
25. Parker JD, Parker AB, Farrell B, Parker JO (1996) Effects of diuretic therapy on the development of tolerance to nitroglycerin and exercise capacity in patients with chronic stable angina. Circulation 93:691-696