Platelet-activating factor in the CNS

Progress in Neurobiology

Volumn 50, Issue 5-6, 1996, Pages 585-596

  Maclennan, Karyn M ^a   Smith, Paul F ^a   Darlington, Cynthia L ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 3 [1 [5 METHYLTHIOMETHYL 6 OXO 3 (2 OXO 3 CYCLOPENTEN 1 YLIDENE) 2 PIPERAZINYL]ETHYL] 2 INDOLINONE; 2 [N (2 METHOXY 3 OCTADECYLCARBAMOYLOXYPROPOXYCARBONYL)ACETAMIDOMETHYL] 1 ETHYLPYRIDINIUM CHLORIDE; 2,3 DIHYDRO 5 [4 (3,4,5 TRIMETHOXYPHENETHYL)PHENYL]IMIDAZO[2,1 A]ISOQUINOLINE; 3 (3,4 METHYLENEDIOXYBENZYL) 4 (3,4,5 TRIMETHOXYBENZYL)TETRAHYDROFURAN; 3 BROMO 5 [N PHENYL N [2 [[2 (1,2,3,4 TETRAHYDRO 2 ISOQUINOLYLCARBONYLOXY)ETHYL]CARBAMOYL]ETHYL]CARBAMOYL] 1 PROPYLPYRIDINIUM NITRATE; 6 (2 CHLOROPHENYL) 4,7,8,10 TETRAHYDRO 9 (4 METHOXYPHENYLCARBAMOYL) 1 METHYLPYRIDO[4',3':4,5]THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE; 6 (2 CHLOROPHENYL) 8 DIPROPYLCARBAMOYL 8,9 DIHYDRO 1 METHYL 4H,7H CYCLOPENTA[4,5]THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE; 6 (2 CHLOROPHENYL) 9 [(3,4 DIMETHOXYPHENYL)THIOMETHYLTHIOCARBONYL] 4,7,8,10 TETRAHYDRO 1 METHYLPYRIDO[4',3':4,5]THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE; APAFANT; BEPAFANT; BN 50726; BN 50727; BN 52111; GINKGOLIDE; KADSURENONE; RO 74719; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG; YANGAMBIN; [2 METHOXY 3 (N OCTADECYLCARBAMOYLOXY)PROPYL] (2 THIAZOLIOETHYL) PHOSPHATE;

ANIMAL TISSUE; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; GINKGO BILOBA; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; ISCHEMIA; MENINGITIS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030461466     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-0082(96)00047-0     Document Type: Article

References (115)

1. 3 stimulate immediate early gene expression in rat astroglial cultures. Neurochem. Intl 22, 567-574.
2. Arditi, M., Manogue, K. R., Caplan, M. and Yogev, R. (1990) Cerebrospinal fluid cachectin/tumor necrosis factor-α and platelet-activating factor concentrations and severity of bacterial meningitis in children. J. Infect. Dis. 162, 139-147.
3. Arthur, J. F., Shahin, S. and Dusting, G. J. (1995) PAF antagonists block induction of nitric oxide synthase in cultured macrophages and vascular smooth muscle cells. Clin. Expl. Pharmacol. Physiol. 22, 452-454.
4. Azzouzi, B. E., Jurgens, P., Benveniste, J. and Thomas, Y. (1993) Immunoregulatory functions of PAF-acether. IX. Modulation of apoptosis in an immature T cell line. Biochem. Biophys. Res. Commun. 190, 320-324.
5. Baker, R. R. and Chang, H.-Y. (1993) The potential for platelet-activating factor synthesis in brain: properties of cholinephosphotransferase and 1-alkyl-sn-glycero-3-phosphate acetyltransferase in microsomal fractions of immature rabbit cerebral cortex. Biochim. Biophys. Acta 1170, 157-164.
6. 2 and release of arachidonic acid and other lipid mediators at the synapse: The role of platelet-activating factor. J. Lipid Mediat. 6, 421-427.
7. Benveniste, J., Henson, P. M. and Cochrane, C. G. (1972) Leukocyte-dependent histamine release from rabbit platelet: the role of IgE basophils and a platelet activating factor. J. Expl. Med. 136, 1356-1377.
8. Bernardini, R., Calogero, A. E., Ehrlich, Y. H., Brucke, T., Chrousos, G. P. and Gold, P. W. (1989) The alkyl-ether phospholipid platelet-activating factor is a stimulator of the hypothalamic-pituitary adrenal axis in the rat. Endocrinology 125, 1067-1073.
9. Bielenberg, G. W., Wagener, G. and Beck, T. (1992) Infarct reduction by the platelet activating factor antagonist apafant in rats. Stroke 23, 98-103.
10. Birkle, D. L., Kurian, P., Braquet, P. and Bazan, N. G. (1988) Platelet-activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock. J. Neurochem. 51, 1900-1905.
11. 2+ in hippocampal neurons. Neuron 9, 285-294.
12. Blasquez, C., Jegou, S., Delarue, C., Delbende, C., Tranchand Bunel, D., Braquet, P. and Vaudry, H. (1990) Effect of platelet-activating factor on hypothalamic and hypophyseal pro-opiomelanocortin-related peptides and hypothalamo-pituitary-adrenal axis in the rat. Eur. J. Pharmacol. 177, 145-153.
13. Bliss, T. V. and Collingridge, G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
14. Bonavida, B. and Mencia-Huerta, J. M. (1994) Platelet-activating factor and the cytokine network in inflammatory processes. Clin. Rev. Allergy 12, 381-395.
15. Braquet, P. (1987) The ginkgolides: potent platelet-activating factor antagonists isolated from Ginkgo biloba L.: chemistry, pharmacology and clinical applications. Drugs Future 12, 643-699.
16. Braquet, P. and Esanu, A. (1991) New trends in PAF antagonist research: a new series of potent hetrazepine-derived PAF antagonists. Agents Actions 32, 34-36.
17. Braquet, P., Touqui, L., Shen, T. Y. and Vargaftig, B. B. (1987) Perspectives in platelet-activating factor research. Pharmacol. Rev. 39, 97-145.
18. Brodie, C. (1995) Platelet-activating factor induces nerve growth factor production by rat astrocytes. Neurosci. Lett. 186, 5-8.
19. Casals-Stenzel, J. (1991) Thieno-triazolo-1,4-diazepines as antagonists of platelet-activating factor: present status. Lipids 26, 1157-1161.
20. Castro-Faria-Neto, H. C., Bozza, P. T., Cruz, H. N., Silva, C. L. M., Violante, F. A., Barbosa-Filho, J. M., Thomas, G., Martins, M. A., Tibirica, E. V., Noel, F. and Cordeiro, R. S. B. (1995) Yangambin: a new naturally occurring platelet-activating factor receptor antagonist: binding and in vitro functional studies. Planta Med. 61, 101-105.
21. Catalan, R. E., Martinez, A. M., Aragones, M. D., Garde, E. and Diaz, G. (1993) Platelet-activating factor stimulates protein kinase C translocation in cerebral microvessels. Biochem. Biophys. Res. Commun. 192, 446-451.
22. +) ATPase activity in rat brain. Neurosci. Res. 19, 241-244.
23. Ceriani, G., Macaluso, A., Catania, A. and Lipton, J. M. (1994) Central neurogenic anti-inflammatory action of α-MSH: modulation of peripheral inflammation induced by cytokines and other mediators of inflammation. Neuroendocrinology 59, 138-143.
24. Chao, W. and Olson, M. S. (1993) Platelet-activating factor: receptors and signal transduction. Biochem. J. 292, 617-629.
25. Chau, L. Y., Hu, C. Y., Chang, W. T. and Hsu, Y. S. (1992) Possible existence of two subsets of platelet-activating factor receptor to mediate polyphosphoinositide breakdown and calcium influx in neuroblastoma glioma hybrid NG108-15 cells. J. Neurochem. 59, 1090-1098.
26. Clark, G. D., Happel, L. T., Zorumski, C. F. and Bazan, N. G. (1992) Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor. Neuron 9, 1211-1216.
27. Cundell, D. R., Gerard, N. P., Gerard, C., Idanpaan-Heikkila, I. and Tuomanen, E. I. (1995) Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature 377, 435-438.
28. Del Cerro, S., Arai, A. and Lynch, G. (1990) Inhibition of long-term potentiation by an antagonist of platelet-activating factor receptors. Behav. Neural. Biol. 54, 213-217.
29. Dewhurst, S., Gelbard, H. A. and Fine, S. M. (1996) Neuropathogenesis of AIDS. Mol. Med. Today Jan. 16-23.
30. Dominiczak, A. F. and Bohr, D. F. (1995) Nitric oxide and its putative role in hypertension. Hypertension 25, 1202-1211.
31. Doucet, J. P. and Bazan, N. G. (1992) Excitable membranes, lipid messengers, and immediate-early genes. Mol. Neurobiol. 6, 407-424.
32. Edwards, R. M., Trizna, W. and Feuerstein, G. (1991) Platelet-activating factor (PAF) has no direct effect on rat intracerebral arterioles in vitro. J. Lipid Mediat. 3, 161-165.
33. Faden, A. I. and Halt, P. (1992) Platelet-activating factor reduces spinal cord blood flow and causes behavioural deficits after intrathecal administration in rats through a specific receptor mechanism. J. Pharmacol. Expl. Ther. 261, 1064-1070.
34. Faden, A. I. and Tzendzalian, P. A. (1992) Platelet-activating factor antagonists limit glycine changes and behavioural deficits after brain trauma. Am. J. Physiol. 263, R909-R914.
35. Gelbard, H. A., Nottet, H. S. L. M., Swindells, S., Jett, M., Dzenko, K. A., Genis, P., White, R., Wang, L., Choi, Y. B., Zhang, D., Lipton, S. A., Tourtellotte, W. W., Epstein, L. G. and Gendelman, H. E. (1994) Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin. J. Virology 68, 4628-4635.
36. Gilboe, D. D., Kintner, D., Fitzpatrick, J. H., Emoto, S. E., Esanu, A., Braquet, P. G. and Bazan, N. G. (1991) Recovery of postischemic brain metabolism and function following treatment with a free radical scavenger and platelet-activating factor antagonists. J. Neurochem. 56, 311-319.
37. Goda, Y. (1994) In pursuit of a retrograde messenger. Curr. Biol. 4, 148-150.
38. Goracci, G. and Francescangeli, E. (1991) Properties of PAF-synthesizing phosphocholinetransferase and evidence for lysoPAF acetyltransferase activity in rat brain. Lipids 26, 986-991.
39. Gotz, E., Olenik, C., Uhl, A., Seregi, A. and Meyer, D. K. (1993) Meningocortical lesion increases expression of the cholecystokinin gene in rat cerebral cortex: evidence for the involvement of platelet-activating factor (PAF). Mol. Brain Res. 18, 285-289.
40. Guo, Z. M., Qian, C., Peters, C. J. and Liu, C. T. (1993) Changes in platelet-activating factor, catecholamine, and serotonin concentrations in brain, cerebrospinal fluid, and plasma of pichinde virus-infected guinea pigs. Lab. Anim. Sci. 43, 569-574.
41. Handley, D. A. (1990) Preclinical and clinical pharmacology of platelet-activating factor receptor antagonists. Med. Res. Rev. 10, 351-370.
42. Hashimoto, K., Hirasawa, R. and Makino, S. (1993) Comparison of the effects of intra-third ventricular administration of interleukin-1 or platelet-activating factor on ACTH secretion and the sympathetic-adrenomedullary system in conscious rats. Acta Med. Okayama 47, 1-6.
43. Herrick-Davis, K., Camussi, G., Bussolino, F. and Baglioni, C. (1991) Modulation of neunte outgrowth in neuroblastoma cells by protein kinase C and platelet-activating factor. J. Biol. Chem. 266, 18620-18625.
44. Heuer, H. O. (1991) WEB 2347: pharmacology of a new very potent and long acting hetrazepinoic PAF-antagonist and its action in repeatedly sensitized guinea-pigs. J. Lipid Mediat. 4, 39-44.
45. Heuer, H. O., Casals-Stenzel, J., Muacevic, G. and Weber, K. H. (1990) Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor. J. Pharmacol. Expl. Ther. 255, 962-968.
46. Hirashima, Y., Endo, S., Otsuji, T., Karasawa, K., Nojima, S. and Takaku, A. (1993) Platelet-activating factor and cerebral vasospasm following subarachnoid hemorrhage. J. Neurosurg. 78, 592-597.
47. Honda, Z., Nakamura, M., Miki, I., Minami, M., Watanabe, T., Seyama, Y., Okado, H., Toh, H., Ito, K., Miyamoto, T. and Shimizu, T. (1991) Cloning functional expression of platelet-activating factor receptor from guinea-pig lung. Nature 349, 342-346.
48. Hosford, D. and Braquet, P. (1990) Antagonists of platelet-activating factor: chemistry, pharmacology and clinical applications. Progr. Med. Chem. 27, 325-380.
49. Hosford, D. J., Domingo, M. T., Chabrier, P. E. and Braquet, P. (1990) Ginkgolides and platelet-activating factor binding sites. Meth. Enzymol. 187, 433-446.
50. Hunyadi, J., Kenderessy, A. S., Duda, E., Braquet, P. and Dobozy, A. (1993) Platelet-activating factor antagonists (BN 52021 and BN 50730) inhibit tumor necrosis factor-alpha-mediated cytotoxicity on murine L929 tumor cells. Mol. Immunol. 30, 517-519.
51. Hynes, N., Bishai, I., Lees, J. and Coceani, F. (1991) Leukotrienes in brain: natural occurrence and induced changes. Brain Res. 553, 4-13.
52. Ikegami, K., Meade, C. J., Heuer, H. O. and Birke, F. (1992) Hetrazepine PAF antagonists. J. Lipid Mediat. 5, 177-182.
53. Imaizumi, T. A., Stafforini, D. M., Yamada, Y., McIntyre, T. M., Prescott, S. M. and Zimmerman, G. A. (1995) Platelet-activating factor: a mediator for clinicians. J. Intern. Med. 238, 5-20.
54. Izquierdo, I., Fin, C., Schmitz, P. K., Da Silva, R. C., Jerusalinsky, D., Quillfeldt, J. A., Ferreira, M. B. G., Medina, J. H. and Bazan, N. G. (1995) Memory enhancement by intrahippocampal, intraamygdala, or intraentorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task. Proc. Natl. Acad. Sci. U.S.A. 92, 5047-5051.
55. Izumi, T., Honda, Z., Mutoh, H., Kume, K. and Shimizu, T. (1995) Regulation and signal transduction of PAF receptor. Adv. Prostagland. Thrombox. Leukot. Res. 23, 461-466.
56. Jiang, Z. G., Yue, T. L. and Feuerstein, G. (1993) Platelet-activating factor inhibits excitatory transmission in rat neostriatum. Neurosci. Lett. 155, 132-135.
57. Junier, M. P., Tiberghien, C., Rougeot, C., Fafeur, V. and Dray, F. (1988) Inhibitory effect of platelet-activating factor (PAF) on luteinizing hormone-releasing hormone and somatostatin release from rat median eminence in vitro correlated with the characterization of specific PAF receptor sites in rat hypothalamus. Endocrinology 123, 72-80.
58. Karcher, L., Zagermann, P. and Krieglstein, J. (1984) Effect of an extract of ginkgo biloba on rat brain energy metabolism in hypoxia. Arch. Pharmacol. 327, 31-35.
59. Kato, K., Clark, G. D., Bazan, N. G. and Zorumski, C. F. (1994) Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation. Nature 367, 175-179.
60. Kochanek, P. M., Nemoto, E. M., Melick, J. A., Evans, R. W. and Burke, D. F. (1988) Cerebrovascular and cerebrometabolic effects of intracarotid infused platelet-activating factor in rats. J. Cereb. Blood Flow Metab. 8, 546-551.
61. Kochanek, P. M., Melick, J. A., Schoettle, R. J., Magargee, M. J., Evans, R. W. and Nemoto, E. M. (1990) Endogenous platelet-activating factor does not modulate blood flow and metabolism in normal rat brain. Stroke 21, 459-462.
62. Koltai, M., Guinot, P., Hosford, D. and Braquet, P. (1994) Platelet-activating factor antagonists: scientific background and possible clinical applications. Adv. Pharmacol. 28, 81-167.
63. Kornecki, E. and Ehrlich, Y. H. (1988) Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor. Science 240, 1792-1794.
64. Kornecki, E. and Ehrlich, Y. H. (1991) Calcium ion mobilization in neuronal cells induced by PAF. Lipids 26, 1243-1246.
65. Kumar, R., Harvey, S. A. K., Kester, M., Hanahan, D. J. and Olson, M. S. (1988) Production and effects of platelet-activating factor in the rat brain. Biochim. Biophys. Acta 963, 375-383.
66. Lalouette, F., Diserbo, M., Martin, C., Verdetti, J. and Fatome, M. (1995) Presence of specific platelet-activating factor binding sites in neuroblastoma N1E-115 cells. Neurosci. Lett. 186, 173-176.
67. Le Poncin Lafitte, M., Rapin, J. and Rapin, J. R. (1980) Effects of ginkgo biloba on changes induced by quantitative cerebral microembolization in rats. Arch. Intern. Pharmacodyn. 243, 236-244.
68. Lin, A. Y. and Rui, Y. C. (1994) Platelet-activating factor induced calcium mobilization and phosphoinositide metabolism in cultured bovine cerebral microvascular endothelial cells. Biochim. Biophys. Acta 1224, 323-328.
69. Lindsberg, P. J., Hallenbeck, J. M. and Feuerstein, G. (1991) Platelet-activating factor in stroke and brain injury. Ann. Neurol. 30, 117-129.
70. Lustig, H. S., Chan, J. and Greenberg, D. A. (1992) Comparative neurotoxic potential of glutamate, endothelins, and platelet-activating factor in cerebral cortical cultures. Neurosci. Lett. 139, 15-18.
71. Marcheselli, V. L. and Bazan, N. G. (1994) Platelet-activating factor is a messenger in the electroconvulsive shock-induced transcriptional activation of c-fos and zif-268 in hippocampus. J. Neurosci. Res. 37, 54-61.
72. Marcheselli, V. L., Rossowska, M. J., Domingo, M. T., Braquet, P. and Bazan, N. G. (1990) Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex. J. Biol. Chem. 265, 9140-9145.
73. 2 in radical production during ischemia and reperfusion of the rat brain. Brain Res. 709, 296-302.
74. Medina, J. H. and Izquierdo, I. (1995) Retrograde messengers, long-term potentiation and memory. Brain Res. Rev. 21, 185-194.
75. Muirhead, E. E. (1980) Antihypertensive functions of the kidney: Arthur C. Corcoran memorial lecture. Hypertension 2, 444-464.
76. Nishida, K. and Markey, S. P. (1996) Platelet-activating factor in brain regions after transient ischemia in gerbils. Stroke 27, 514-519.
77. Nishida, K., Markey, S. P., Kustova, Y., Morse, H. C., Skolnick, P., Basile, A. S. and Sei, Y. (1996) Increased brain levels of platelet-activating factor in a mutine acquired immune deficiency syndrome are NMDA receptor-mediated. J. Neurochemistry 66, 433-435.
78. Nottet, H. S. L. M., Jett, M., Flanagan, C. R., Zhai, Q. H., Persidsky, Y., Rizzino, A., Bernton, E. W., Genis, P., Baldwin, T., Schwartz, J., LaBenz, C. J. and Gendelman, H. E. (1995) A regulatory role for astrocytes in HIV-I encephalitis. J. Immunol. 154, 3567-3581.
79. Panetta, T., Marcheselli, V. L., Braquet, P., Spinnewyn, B. and Bazan, N. G. (1987) Effects of a platelet-activating antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: inhibition of ischemia-reperfusion induced cerebral injury. Biochem. Biophys. Res. Commun. 149, 580-587.
80. Pettigrew, L. C., Meyer, J. J., Craddock, S. D., Butler, S. M., Tai, H. H. and Yokel, R. A. (1995) Delayed elevation of platelet activating factor in ischemic hippocampus. Brain Res. 691, 243-247.
81. Pinckard, R. N., Woodard, D. S., Showell, H. J., Conklyn, M. J., Novak, M. J. and McManus, L. M. (1994) Structural and (patho)physiological diversity of PAF. Clin. Rev. Allergy 12, 329-359.
82. Prehn, J. H. M. and Krieglstein, J. (1993) Platelet-activating factor antagonists reduce excitotoxic damage in cultured neurons from embryonic chick telencephalon and protect the rat hippocampus and neocortex from ischemic injury in vivo. J. Neurosci. Res. 34, 179-188.
83. Righi, M., Letari, O., Sacerdote, P., Marangoni, F., Miozzo, A. and Nicosia, S. (1995) myc-immortalized microglial cells express a functional platelet-activating factor receptor. J. Neurochem. 64, 121-129.
84. Rougeot, C., Junier, M. P., Minary, P., Weidenfeld, J., Braquet, P. and Dray, F. (1990) Intracerebroventricular injection of platelet-activating factor induces secretion of adrenocorticotropin, beta-endorphin and corticosterone in conscious rats: a possible link between the immune and nervous systems. Neuroendocrinology 51, 267-275.
85. Satoh, K., Imaizumi, T., Yoshida, H., Hiramoto, M. and Takamatsu, S. (1992) Increased levels of blood platelet-activating factor (PAF) and PAF-like lipids in patients with ischemic stroke. Acta Neurol. Scand. 85, 122-127.
86. Shimizu, T., Honda, Z., Nakamura, M., Bito, H. and Izumi, T. (1992) Platelet-activating factor receptor and signal transduction. Biochem. Pharmacol. 44, 1001-1008.
87. Shukla, S. D. (1992) Platelet-activating factor receptor and signal transduction mechanisms. FASEB J. 6, 2296-2301.
88. Siren, A. L., Liu, Y., Feuerstein, G. and Hallenbeck, J. M. (1993) Increased release of tumor necrosis factor-α into the cerebrospinal fluid and peripheral circulation of aged rats. Stroke 24, 880-888.
89. Smith, P. F., Maclennan, K. and Darlington, C. L. (1996) The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF). J. Ethnopharmacol. 50, 131-139.
90. Snyder, F. (1994) Metabolic processing of PAF. Clin. Rev. Allergy 12, 309-327.
91. Snyder, F. (1995) Platelet-activating factor and its analogs: metabolic pathways and related intracellular processes. Biochim. Biophys. Acta 1254, 231-249.
92. Sogos, V., Bussolino, F., Pilia, E., Torelli, S. and Gremo, F. (1990) Acetylcholine-induced production of platelet-activating factor by human fetal brain cells in culture. J. Neurosci. Res. 27, 706-711.
93. Spinnewyn, B., Blavet, N., Clostre, F., Bazan, N. and Braquet, P. (1987) Involvement of platelet-activating factor (PAF) in cerebral post-ischemic phase in mongolian gerbils. Prostaglandins 34, 337-349.
94. Squinto, S. P., Block, A. L., Braquet, P. and Bazan, N. G. (1989) Platelet-activating factor stimulates a fos/jun/AP-1 transcriptional signaling system in human neuroblastoma cells. J. Neurosci. Res. 24, 558-566.
95. 2) is expressed in human brain astrocytes. Brain Res. 637, 97-105.
96. Sun, D. and Gilboe, D. D. (1994) Effect of platelet-activating factor antagonist BN 50739 and its diluents on mitochondrial respiration and membrane lipids during and following cerebral ischemia. J. Neurochem. 62, 1929-1938.
97. Szabo, C., Wu, C. C., Mitchell, J. A., Gross, S. S., Thiemermann, C. and Vane, J. R. (1993) Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide. Circ. Res. 73, 991-999.
98. 2+/ascorbate/EDTA-induced lipid peroxidation. Biochem. Biophys. Acta 1166, 264-274.
99. Terashita, Z. I., Takatani, M. and Nishikawa, K. (1992) Pharmacological profile of TCV-309 - a potent PAF antagonist. J. Lipid Mediat. 5, 183-185.
100. Tiberghien, C., Laurent, L., Junier, M. P. and Dray, F. (1991) A competitive receptor binding assay for platelet-activating factor (PAF): quantification of PAF in rat brain. J. Lipid Mediat. 3, 249-266.
101. Tokumura, A., Yotsumoto, T., Hoshikawa, T., Tanaka, T. and Tsukatani, H. (1992) Quantitative analysis of platelet-activating factor in rat brain. Life Sci. 51, 303-308.
102. Tokutomi, T., Sigemori, M., Kikuchi, T. and Hirohata, M. (1994) Effect of platelet-activating factor antagonist on brain injury in rats. Acta Neurochir. 60, 508-510.
103. Uemura, Y., Lee, T. C. and Snyder, F. (1991) A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway. J. Biol. Chem. 266, 8268-8272.
104. Ved, H. S., Gustow, E. and Pieringer, R. A. (1991) Regulation of neuronal differentiation in neuron-enriched primary cultures from embryonic rat cerebra by platelet-activating factor and the structurally related glycerol ether lipid, dodecylglycerol. J. Neurosci. Res. 30, 353-358.
105. Venable, M. E., Zimmerman, G. A., McIntyre, T. M. and Prescott, S. M. (1993) Platelet-activating factor: a phospholipid autocoid with diverse actions. Lipid Res. 34, 691-702.
106. i protein. J. Neurochem. 63, 1720-1725.
107. Wieraszko, A., Li, G., Kornecki, E., Hogan, M. V. and Ehrlich, Y. H. (1993) Long-term potentiation in the hippocampus induced by platelet-activating factor. Neuron 10, 553-557.
108. Willard, A. L. (1992) Excitatory and neurotoxic actions of platelet-activating factor on rat myenteric neurons in cell culture. Am. NY Acad. Sci. 664, 284-292.
109. Ye, R. D., Prossnitz, E. R., Zou, A. and Cochrane, C. G. (1991) Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. Biochem. Biophys. Res. Commun. 180, 105-111.
110. Yue, T. L. and Feuerstein, G. Z. (1994) Platelet-activating factor: a putative neuromodulator and mediator in the pathophysiology of brain injury. Crit. Rev. Neurobiol. 8, 11-24.
111. Yue, T. L., Lysko, P. G. and Feuerstein, G. (1990) Production of platelet-activating factor from rat cerebellar granule cells in culture. J. Neurochem. 54, 1809-1811.
112. Yue, T. L., Gleason, M. M., Hallenbeck, J. and Feuerstein, G. (1991a) Characterization of platelet-activating factor-induced elevation of cytosofic free-calcium level in neurohybrid NCB-20 cells. Neuroscience 41, 177-185.
113. Yue, T. L., Gleason, M. M., Gu, J. L., Lysko, P. G., Hallenbeck, J. and Feuerstein, G. (1991b) Platelet-activating factor (PAF) receptor-mediated calcium mobilization and phosphoinositide turnover in neurohybrid NG108-15 cells: studies with BN50739, a new PAF antagonist. J. Pharmacol. Expl. Ther. 257, 374-381.
114. Zablocka, B., Lukasiuk, K., Lazarewicz, J. W. and Domanska-Janik, K. (1995) Modulation of ischemic signal by antagonists of N-methyl-D-aspartate, nitric oxide synthase, and platelet-activating factor in gerbil hippocampus. J. Neurosci. Res. 40, 233-240.
115. Zimmerman, G. A., Prescott, S. M. and McIntyre, T. M. (1995) Oxidatively fragmented phospholipids as inflammatory mediators: the dark side of polyunsaturated lipids. J. Nutr. 125, 1661S-1665S.