Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injury

Journal of Clinical Investigation

Volumn 98, Issue 12, 1996, Pages 2666-2673

  Barazzone, Constance ^a,b   Belin, Dominique ^a   Piguet, Pierre François ^a   Vassalli, Jean Dominique ^a   Sappino, André Pascal ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Centre médical universitaire   (Switzerland)

Author keywords

fibrin; fibrinolysis; hyperoxia; plasmin; proteases

Indexed keywords

CARBON DIOXIDE; OXYGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FIBRIN METABOLISM; FIBRINOLYSIS; HISTOPATHOLOGY; HYALINE MEMBRANE DISEASE; HYPEROXIA; IMMUNOHISTOCHEMISTRY; LUNG INJURY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL;

EID: 0030454095     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119089     Document Type: Article

References (39)

1. Crapo, J.D., B.E. Barry, H.A. Foscue, and J. Shelburne. 1980. Structural and biochemical changes in rat lungs occurring during exposure to lethal and adaptive doses of oxygen. Am. Rev. Respir. Dis. 122:123-143.
2. Basset, F.V., V.J. Ferrans, P. Soler, P. Takemura, Y. Fukuda, and R.G. Crystal. 1986. Intraluminal fibrosis in interstitial lung disorders. Am. J. Pathol. 122:443-461.
3. Danø, K., P.A. Andreasen, J. Grøndhal-Hansen, P. Kristensen, L.S. Nielsen, and L. Shriver. 1985. Plasminogen activators, tissue degradation, and cancer. Adv. Cancer Res. 44:139-266.
4. Sawdey, M.S., and D.J. Loskutoff. 1991. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. J. Clin. Invest. 88:1346-1353.
5. Suffredini, A.F., P.C. Harpel, and J.E. Parillo. 1989. Promotion and subsequent inhibition of plasminogen activation after administration of intravenous endotoxin to normal subjects. N. Engl. J. Med. 320:1165-1172.
6. Moll, S., P.A. Menoud, T. Fulpius, Y. Pastore, S. Takahashi, L. Fossati, J.D. Vassalli, A.P. Sappino, and S. Izui. 1995. Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis. Kidney Int. 48: 1459-1468.
7. Bertozzi, P., B. Astedt, L. Zenzius, K. Lynch, F. Lemaire, W. Zapol, and H. Chapman. 1990. Depressed bronchoalveolar urokinase activity in patients with adult respiratory distress syndrome. N. Engl. J. Med. 322:890-897.
8. Idell, S., K.K. James, T.R. Martin, J. McLarty, and R. Maunder. 1991. Trended abnormalities of fibrin turnover in evolving adult respiratory distress syndrome. Am. J. Lung Cell. Mol. Physiol. 5:L240-L248.
9. White, J.E., M. Ryan, M.F. Tsan, and P.J. Higgins. 1993. Hyperoxic stress elevates p52(PAI-1) mRNA abundance in cultured cells and adult rat pulmonary tissue. Am. J. Physiol. 265:L121-L126.
10. Barazzone, C., F. Tacchini-Cottier, C. Vesin, A. Rochat, and P.F. Piguet. 1996. Hyperoxia induces platelet activation and lung sequestration: an event dependent on tumor necrosis factor-α and CD11a. Am. J. Respir. Cell Mol. Biol. 15:107-114.
11. Carmeliet, P., L. Kieckens, L. Schoonjans, B. Ream, A. Van Nuffelen, G. Prendergast, M. Cole, R. Bronson, D. Collen, and R.C. Mulligan. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin. Invest 92:2746-2755.
12. Canneliet, P., L. Schoonjans, L. Kieckens, B. Ream, J. Degen, R. Bronson, R. De Vos, J.J. van der Oord, D. Collen, and R.C. Mulligan. 1994. Physiological consequences of loss of plasminogen activator gene function in mice. Nature (Lond.). 368:419-424.
13. Busso, N., D. Belin, C. Failly-Crépin, and J.D. Vassalli. 1986. Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). J. Biol. Chem. 261:9309-9315.
14. Sappino, A.P., J. Huarte, J.D. Vassalli, and D. Belin. 1991. Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney. J. Clin. Invest. 87:962-970.
15. Sappino, A.P., R. Madani, J. Huarte, D. Belin, J.Z. Kiss, A.L. Wohlwend, and J.D. Vassalli. 1993. Extracellular proteolysis in the adult murine brain. J. Clin. Invest. 92:679-685.
16. Belin, D., A.L. Wohlwend, W.D. Schleuning, E.K. Kruithof, and J.D. Vassalli. 1989. Facultative polypeptide translocation allows a single mRNA to encode the secreted and the cytosolic form of plasminogen activator inhibitor 2. EMBO (Eur. Mol. Biol. Organ.) J. 8:3287-3294.
17. 2-antiplasmin production. J. Clin. Invest. 97:2478-2484.
18. Vassalli, J.D., J. Huarte, D. Bosco, A.P. Sappino, N. Sappino, A. Velardi, A. Wohlwend, H. Ernø, D. Monard, and D. Belin. 1993. Protease-nexin I as an androgen-dependent secretory product of the murine seminal vesicle. EMBO (Eur. Mol. Biol Organ.) J. 12:1871-1878.
19. Belin, D. 1994. The use of riboprobes for the analysis of gene expression. In Protocols for Gene Analysis. Vol. 31. A.J. Harwood, editor. Humana Press Inc., Towota, NJ. 257-272.
20. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
21. Vassalli, J.D., J.M. Dayer, A. Wohlwend, and D. Belin. 1984. Concomitant secretion of prourokinase and of plasminogen activator-specific inhibitor by stimulated macrophages. J. Exp. Med. 159:1653-1668.
22. Vassalli, J.D., and D. Belin. 1987. Amiloride selectively inhibits the urokinase-type plasminogen activator. FEBS Lett. 214:187-191.
23. Idell, S., K.K. James, B. Levine, B.S. Schwartz, N. Manchanda, R.J. Maunder, T.R. Martin, J. McLarty, and S. Fair. 1989. Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome. J Clin. Invest. 84:695-705.
24. Kuhn, C., and J.A. McDonald. 1991. The roles of the myofibroblasts in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular synthesis. Am. J. Pathol. 138:1257-1265.
25. Mc Donald, J.A. 1991. Idiopathic pulmonary fibrosis. A paradigm for lung injury and repair. Chest. 99:87S-93S.
26. Olman, M.A., N. Mackman, C.L. Gladson, K.M. Moser, and D.J. Loskutoff. 1995. Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse. J. Clin. Invest. 96:1621-1630.
27. Biemond, B.J., M. Levi, H. TenCate, T. Van der Poll, H.R. Büller, C.E. Hack, and J.W. TenCate. 1995. Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of intervention in the cytokine and coagulation cascade. Clin. Sci. 88:587-594.
28. Idell, S., A. Kumar, K.B. Koenig, and J.J. Coalson. 1994. Pathways of fibrin turnover in lavage of premature baboons with hyperoxic lung injury. Am. J. Respir. Crit. Care Med. 149:767-775.
29. Gross, T., R. Simon, C. Kelley, and R. Sitrin. 1991. Rat alveolar epithelial cells concomitantly express plasminogen activator inhibitor-1 and urokinase. Am. J. Physiol. 260:L286-L295.
30. Loskutoff, D.J., and T.S. Edgington. 1977. Synthesis of a fibrinolytic activator and inhibitor by endothelial cells. Proc. Natl. Acad. Sci. USA. 74:3903-3907.
31. Chapman, H.A., X.L. Yang, L.Z. Sailor, and D.J. Sugarbaker. 1990. Developmental expression of plasminogen activator inhibitor type 1 by human alveolar macrophages. Possible role in lung injury. J. Immunol. 145:3398-3405.
32. Varani, J., R.G. Sitrin, and W. Hillegas. 1992. Expression of plasminogen activator and plasminogen activator inhibitor mRNA in human fibroblasts grown on different substrates. Cytotechnology. 9:157-162.
33. Hagood, J.S., M.A. Olman, J.A. Godoy, K.E. Rivera, and G.M. Fuller. 1996. Regulation of type I plasminogen activator inhibitor by fibrin degradation products in rat lung fibroblasts. Blood. 87:3749-3757.
34. Singhal, K.K., and L.A. Parton. 1996. Plasminogen activator activity in preterm infants with respiratory distress syndrome: relationship to the development of bronchopulmonary dysplasia. Ped. Res. 39:229-235.
35. Viscardi, R., K. Broderick, C.C. Sun, A.J. Yale-Loehr, A. Hessamfar, V. Taciak, K.C. Burke, K.B. Koenig, and S. Idell. 1992. Disordered pathways of fibrin turnover in lung lavage of premature infants with respiratory distress syndrome. Am. Rev. Respir. Dis. 146:492-499.
36. Eitzman, D.T., R.D. McCoy, X. Zheng, W.P. Fay, D. Ginsburg, and R.H. Simon. 1996. Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J. Clin. Invest. 97:232-237.
37. Seeger, W., G. Stoehr, H.D. Wolf, and H. Neuhof. 1985. Alteration of surfactant function due to protein leakage: special interaction with fibrin monomer. J. Appl. Physiol. 58:326-338.
38. Halliday, H.L. 1995. Overview of clinical trials comparing natural and synthetic surfactants. Biol Neonate. 67:32-47.
39. Hart, D.A., P. Whidden, F. Green, J. Henkin, and D.E. Woods. 1994. Partial reversal of established bleomycin-induced pulmonary fibrosis by rhurokinase in a rat model. Clin. Invest. Med. 17:69-76.