The kidney is a major site of α2-antiplasmin production

Journal of Clinical Investigation

Volumn 97, Issue 11, 1996, Pages 2478-2484

  Menoud, Pierre Alain ^a   Sappino, Nahid ^a   Boudal Khoshbeen, Mary ^a   Vassalli, Jean Dominique ^b   Sappino, André Pascal ^a,c  

^a Department of Medicine   (Switzerland)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c Centre médical universitaire   (Switzerland)

Author keywords

fibrinolysis; plasmin; plasminogen; proteolysis; serpins

Indexed keywords

ALPHA 2 ANTIPLASMIN; COMPLEMENTARY DNA; MESSENGER RNA; TESTOSTERONE PROPIONATE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; KIDNEY PARENCHYMA; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; RNA ANALYSIS; RNA TRANSCRIPTION; TISSUE DISTRIBUTION; TUMOR CELL LINE;

EID: 0029992343     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118694     Document Type: Article

References (41)

1. Aoki, N. 1990. Molecular genetics of alpha-2-plasmin inhibitor. Adv. Exp. Med. Biol. 281:195-200.
2. Saito, H. 1988. Alpha-2-plasmin inhibitor and its deficiency states. J. Lab. Clin. Med. 112:671-678.
3. Sumi, Y., Y. Ichikawa, Y. Nakamura, O. Miura, and N. Aoki. 1989. Expression and characterization of pro alpha-2-plasmin inhibitor. J. Biochem. (Tokyo). 106:703-707.
4. Tone, M., R. Kikuno, A. Kume Iwaki, and T. Hashimoto Gotoh. 1987. Structure of human alpha-2-plasmin inhibitor deduced from the cDNA sequence. J. Biochem. (Tokyo). 102:1033-1041.
5. Keohane, M.E., S.W. Hall, S.R. VandenBerg, and S.L. Gonias. 1990. Secretion of alpha-2-macroglobulin, alpha-2-antiplasmin, and plasminogen activator inhibitor-1 by glioblastoma multiform in primary organ culture. J. Neurosurg. 73:234-241.
6. Kloczko, J., M. Bielawiec, J. Giedrojc, P. Radziwon, and M. Galar. 1990. Human monocytes release plasma serine protease inhibitors in vitro. Haemostasis. 20:229-232.
7. Harrison, P., and E.M. Cramer. 1993. Platelet alpha-granules. Blood Rev. 7:52-62.
8. Vassalli, J.D., A.P. Sappino, and D. Belin. 1991. The plasminogen activator/plasmin system. J. Clin. Invest. 88:1067-1072.
9. Jensen, P.J., J. Baird, S. Morioka, S. Lessin, and G.S. Lazarus. 1988. Epidermal plasminogen activator is abnormal in cutaneous lesions. J. Invest. Dermatol. 90:777-782.
10. Morioka, S., G.S. Lazarus, J.L. Baird, and P.J. Jensen. 1987. Migrating keratinocytes express urokinase-type plasminogen activator. J. Invest. Dermatol. 88:418-123.
11. Moll, S., J.A. Schifferli, J. Huarte, R. Lemoine, J.-D. Vassalli, and A.-P. Sappino. 1994. LPS induces major changes in the extracellular proteolytic balance in the murine kidney. Kidney Int. 45:500-508.
12. Sappino, A.P., J. Huarle, J.D. Vassalli, and D. Belin. 1991. Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney. J. Clin. Invest. 87:962-970.
13. Sappino, A.P., R. Madani, J. Huarte, D. Belin, J.Z. Kiss, A. Wohlwend. and J.D. Vassalli. 1993. Extracellular proteolysis in the adult murine brain. J. Clin. Invest. 92:679-685.
14. Soreq, H., and R. Miskin. 1981. Plasminogen activator in the rodent brain. Brain Res. 216:361-374.
15. Macfarlane, D.E., and C.E. Dahle. 1993. Isolating RNA from whole blood: the dawn of RNA-based diagnosis? Nature (Lond.). 362:186-188.
16. Feinberg, A.P., and B. Vogelstein. 1983. A technique for radiolabelling DNA restriction endonuclease fragment to high specific activity. Anal. Biochem. 132:6-13.
17. Ausubel, F.M., R. Brent, R.E. Kingston, D.D. Moore, J.A. Smith, J.G. Seidman, and K. Struhl. 1993. Current Protocols in Molecular Biology. K. Janssen, editor. Greene Publishing Associates and Wiley Interscience, New York.
18. Pearson, W.R., and D.J. Lipman. 1988. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA. 85:2444-2448.
19. Belin, D., J.-D. Vassalli, C. Combepine, F. Godeau, Y. Nagamine, E. Reich, H.P. Kocher, and R.M. Duvoisin. 1985. Cloning, nucleotide sequencing and expression of cDNAs encoding mouse urokinase-type plasminogen activator. Eur. J. Biochem. 148:225-232.
20. Rickles, R.J., A.L. Darrow, and S. Strickland. 1988. Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation. J. Biol. Chem. 263: 1563-1569.
21. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
22. Sappino, A.P., J. Huarte, D. Belin, and J.D. Vassalli. 1989. Plasminogen activators in tissue remodeling and invasion. mRNA localization in mouse ovaries and implanting embryos. J. Cell Biol. 109:2471-2479.
23. Vassalli, J.-D., J. Huarte, D. Bosco, A.-P. Sappino, N. Sappino, A. Velardi, A. Wohlwend, H. Erno, D. Monard, and D. Belin. 1993. Protease-nexin I as an androgen-dependent secretory product of the murine seminal vesicle. EMBO (Eur. Mol. Biol. Organ.) J. 12:1871-1878.
24. Carmeliet, P., L. Schoonjans, L. Kieckens, B. Ream, J. Degen, R. Bronson, R. De Vos, J.J. van den Oord, D. Collen, and R.C. Mulligan. 1994. Physiological consequence of loss of plasminogen activator gene function in mice. Nature (Lond.). 368:419-424.
25. Asadi, F.K., D.D. Dimaculangan, and F.G. Berger. 1994. Androgen regulation of gene expression in primary epithelial cells of the mouse kidney. Endocrinology. 134:1179-1187.
26. Cartier, N., R. Lacave, V. Vallet, J. Hagege, R. Hellio, S. Robine, E. Pringault, F. Cluzeaud, P. Briand, and A. Kahn. 1993. Establishment of renal proximal tubule cell lines by targeted oncogenesis in transgenic mice using the L-pyruvate kinase-SV40 (T) antigen hybrid gene. J. Cell Sci. 104:695-704.
27. 1-antitrypsin for structure and function of serpins. Biochemistry. 28:8951-8966.
28. Sachs, A., and E. Wahle. 1993. Poly(A) tail metabolism and function in eukaryotes. J. Biol. Chem. 268:22955-22958.
29. von Heijne, G. 1986. A new method for predicting signal sequence cleavage site. Nucleic Acids Res 14:4683-4690.
30. Christensen, S., and L. Sottrup Jensen. 1992. Bovine alpha-2-antiplasmin. N-terminal and reactive site sequence. FEBS Lett. 312:100-104.
31. Kimura, S., and N. Aoki. 1986. Cross-linking site in fibrinogen for alpha-2-plasmin inhibitor. J. Biol. Chem. 261:15591-15595.
32. 1-plasmin inhibitor. J. Biochem. 99:1699-1705.
33. Carrell, R.W., D.L. Evans, and P.E. Stein. 1991. Mobile reactive centre of serpins and control of thrombosis. Nature (Lond.). 353:576-578.
34. Holmberg, L., I. Lecander, and B. Astedt. 1980. Binding of urokinase to plasma proteinase inhibitors. Scand. J. Clin. Lab. Invest. 40:743-747.
35. Samama, M., M. Castel, O. Matsuo, M. Hoylaerts, and H.R. Lijnen. 1982. Comparative study of the activity of high and low molecular weight urokinase in the presence of fibrin. Thromb. Haemost. 47:36-40.
36. Storkel, S., and E. van den Berg. 1995. Morphological classification of renal cancer. World J. Urol. 13:153-158.
37. Meseguer, A., and J.F. Catterall. 1987. Mouse kidney androgen-regulated protein messenger ribonucleic acid is expressed in the proximal convoluted tubules. Mol. Endocrinol. 1:535-541.
38. Berger, F.G., and G. Watson. 1989. Androgen-regulated gene expression. Annu. Rev. Physiol. 51:51-65.
39. Catterall, J.F., K.K. Kontula, C.S. Watson, P.J. Seppänen, B. Funkenstein, E. Melanitou, N.J. Hickok, C.W. Bardin, and O.A. Jänne. 1986. Regulation of gene expression by androgens in murine kidney. Recent Prog. Horm. Res. 42:71-109.
40. Henderson, C.J., and C.R. Wolf. 1991. Evidence that the androgen receptor mediates sexual differentiation of mouse renal cytochrome P450 expression. Biochem. J. 278:499-503.
41. Rella, C., M. Coviello, M. Quaranta, and A. Paradiso. 1993. Tissue-type plasminogen activator as marker of functional steroid receptors in human breast cancer. Thromb. Res. 69:209-220.