Increased susceptibility to the pathogenic effects of wild-type and recombinant herpesviruses in MPS VII mice compared to normal siblings

Journal of NeuroVirology

Volumn 2, Issue 6, 1996, Pages 417-422

  Wolfe, John H ^a   Martin, Claudia E ^b   Deshmane, Satish L ^b,c   Reilly, John J ^a   Kesari, Santosh ^b   Fraser, Nigel W ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WISTAR INSTITUTE   (United States)

^c Department of Molecular Biology and Genetics   (United States)

Author keywords

Anesthesia; Gene therapy; Herpesvirus vector; Lysosomal storage disease; MPS VII; Pathogenicity; glucuronidase

Indexed keywords

BETA GLUCURONIDASE; GAMMA GLOBIN; VIRUS ANTIBODY; VIRUS VECTOR;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE PREDISPOSITION; ENZYME DEFICIENCY; GENE THERAPY; GENE TRANSFER; HERPES VIRUS; INFLAMMATION; MORTALITY; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; NERVE DEGENERATION; NONHUMAN; PASSIVE IMMUNIZATION; PATHOGENICITY; PRIORITY JOURNAL; STRESS; VIRUS REPLICATION; VIRUS VIRULENCE;

EID: 0030450135     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289609146908     Document Type: Article

References (19)

1. Birkenmeier EH, Davisson MT, Beamer WG, Ganschow RE, Vogler CA, Gwynn B, Lyford KA, Maltais LM, Wawrzyni CJ (1989). Murine mucopolysaccharidosis type VII: Characterization of a mouse with β-glucuronidase deficiency. J Clin Invest 83: 1258-1266.
2. Deatly AM, Spivack JG, Lavi E, Fraser NW (1987). RNA from an immediate early region of the HSV-1 genome is present in the trigeminal ganglia of latently infected mice. Proc Nat Acad Sci USA 84: 3204-3208.
3. Deshmane SL, Valyi-Nagy T, Block T, Maggioncalda J, Wolfe JH, Dillner A, Fraser NW (1995). An HSV-1 containing the rat β-glucuronidase cDNA inserted within the LAT gene is less efficient than the parental strain at establishing a transcriptionally active state during latency in neurons. Gene Therapy 2: 209-217.
4. Haskins ME, Desnick RJ, DiFerrante N, Jezyk P, Patterson DF (1984). Beta-glucuronidase in a dog: A model of mucopolysaccharidosis VII. Ped Res 18: 980-984.
5. Kastrukoff LF, Lau AS, Patterson ML (1986). Genetics of natural resistance to herpes simplex type 1 latent infection of the peripheral nervous system in mice. J Gen Virol 67: 613-621.
6. Lopez C (1975). Genetics of natural resistance to herpes virus infections in mice. Nature 258: 152-153.
7. MacLean EA, Fareed MU, Robertson L, Harland J, Brown SM (1991). Herpes simplex virus type i deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in a Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence. J Gen Virol 72: 631-639.
8. Neufeld EF, Muenzer J (1995). The mucopolysaccharidoses. In: Metabolic Basis of Inherited Disease 7th ed, Scriver CR, Beaudet AL, Sly WS, Valle D, (eds). McGraw Hill: NY, pp. 2465-2494.
9. Sands MS, Birkenmeir EH (1993). A single base-pair deletion in the b-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII. Proc Natl Acad Sci USA 90: in press.
10. Shimeld C, Hill TJ, Blyth WA, Easty DL (1990). Passive immunization protects the mouse eye from damage from herpes simplex virus infection by limiting spread of virus in the nervous system. J Gen Virol 71: 681-687.
11. Sly WS, Quinton BA, McAlister WH, Rimoin DL (1973). β-glucuronidase deficiency. Report of clinical, radiologic and biochemical features of a new mucopolysaccharidosis. J Pediatr 82: 249-257.
12. Snyder EY, Wolfe JH (1996). CNS cell tranplantation: a novel therapy for storage diseases? Curr Opin Neurology 9: 126-136.
13. Snyder EY, Taylor RM, Wolfe JH (1995). Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain. Nature 374: 367-370.
14. Spivack JG, Fareed MU, Valyi-Nagy T, Nash TC, O'Keefe JS, Gesser RM, McKie EA, MacLean AR, Fraser NW, Brown SM (1995). Replication, establishment of latent infection, expression of the latency-associated transcripts and explant reactivation of herpes simplex virus type 1 gamma 34.5 mutants in a mouse eye model. J Gen Virol 76: 321-332.
15. Thomas EE, Lau AS, Kim SU, Osborne D, Kastrukoff LF (1991). Variation in resistance to herpes simplex virus type 1 of oligodendrocytes derived from inbred strains of mice. J Gen Virol 72: 2051-2057.
16. Wolfe JH, Deshmane SL, Fraser NW (1992a). Herpesvirus vector gene transfer and expression of β-glucuronidase in the central nervous system of MPS VII mice. Nature Genetics 1: 379-384.
17. Wolfe JH, Hardy WD Jr (1989). Immunogenetics of murine and feline retroviruses. In: Human Immunogenetics Litwin, SD (ed)., Marcel Dekker Inc., New York: NY, pp. 561-595.
18. Wolfe JH, Sands MS (1996). Murine mucopolysaccharidosis type VII: a model system for somatic gene therapy of the central nervous system. In: Protocols for Gene Transfer in Neuroscience: Towards Gene Therapy of Neurologic Disorders, Lowenstein PR and Enquist LW, (eds). John Wiley and Sons, Essex: England. pp. 263-274.
19. Wolfe JH, Sands MS, Barker JE, Rowe LB, Gwynn B, Vogler CA, Birkenmeier EH (1992b). Reversal of pathology in murine mucopolysaccahridosis type VII by somatic cell gene transfer. Nature 360: 749-753.