The peptide binding specificity of the MHC class II I-A molecule of the Lewis rat, RT1.BI

International Immunology

Volumn 8, Issue 12, 1996, Pages 1825-1832

  Reizis, Boris ^a   Mor, Felix ^a   Eisenstein, Miriam ^a   Schild, Hansjörg ^b   Stefanoviç, Stefan ^b   Rammensee, Hans Georg ^b   Cohen, Irun R ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Antigen presentation; Autoimmunity; Peptide motifs

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS II; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RATS, INBRED LEW; T-LYMPHOCYTES;

EID: 0030445825     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.12.1825     Document Type: Article

References (40)

1. Madden, D. R. 1995. The three-dimensional structure of peptide-MHC complexes. Annu. Rev. Immunol. 13:587.
2. Hammer, J., Gallazzi, F., Bono, E., Karr, W. E., Guenot, J., Valsasnini, P., Nagy, Z. and Sinigaglia, F. 1995. Peptide binding specificity of HLA-DR molecules: correlation with rheumatoid arthritis association. J. Exp. Med. 181:1847.
3. Wucherpfennig, K. W., Yu, B., Bhol., K., Monos, D. S., Argyris, E., Karr, R. W., Ahmed, A. R. and Strominger, J. L. 1995. Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris. Proc. Natl Acad. Sci. USA 92:11935.
4. Rammensee, H.-G. 1995. Chemistry of peptides associated with MHC class I and class II molecules. Curr. Opin. Immunol. 7:85.
5. Hammer, J., Takacs, B. and Sinigaglia, F. 1992. Identification of a motif for HLA-DR1 binding peptides using M13 display libraries. J. Exp. Med. 176:1007.
6. Hammer, J., Bono, E., Gallazzi, F., Belunis, C., Nagy, Z. and Sinigaglia, F. 1994. Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning. J. Exp. Med. 180:2353.
7. Marshall, K. W., Wilson, K. J., Liang, J., Woods, A., Zaller, D. and Rothbard, J. B. 1995. Prediction of peptide affinity to HLA DRB1*0401. J. Immunol. 154:5927.
8. Falk, K., Rotzschke, O., Stefanoviç, S., Jung, G. and Rammenzee, H.-G. 1994. Pool sequencing of natural HLA-DR, DQ and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules. Immunogenetics 39:230.
9. Schild, H., Grüneberg, U., Pougialis, G., Wallny, H.-J., Keilholz, W., Stefanoviç, S. and Rammensee, H.-G. 1995. Natural ligand motifs of H-2E molecules are allele specific and illustrate homology to HLA-DR molecules. Int. Immunol. 7:1957.
10. Vogt, A. B., Kropshofer, H., Kallbacher, H., Kalbus, M., Rammensee, H.-G., Coligan J. E. and Martin. R. 1994. Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides. J. Immunol. 153:1665.
11. Reay, P. A., Cantor, R. M. and Davis, M. M. 1994. Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103). J. Immunol. 152:3946.
12. Brown, J. H., Jardetzky, T. S., Gorga, J. C., Stern, L. J., Urban, R. G., Strominger, J. L. and Wiley, D. C. 1993. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364:33.
13. Stern, L. J., Brown, J. H., Jardetzky, T. S., Gorga, J. C., Urban, R. G., Strominger, J. L. and Wiley, D. C. 1994. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368:215.
14. Rammensee, H.-G., Friede, T. and Stefanoviç, S. 1995. MHC ligands and peptide motifs: first listing. Immunogenetics 41:178.
15. Cohen, I. R. and Miller, A., eds. 1994. Autoimmune Disease Models. A Guidebook. Academic Press, San Diego, CA.
16. Friedman, A., Reshef, T. and Cohen, I. R. 1992. Induction of experimental autoimmune encephalomyelitis by native myelin basic protein-activated T lymphocyte lines. Eur. J. Immunol. 22:279.
17. Holoshitz, J., Matitiau, A. and Cohen, I. R. 1984. Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II. J. Clin. Invest. 73:211.
18. Buus, S., Sette, A., Colon, S. M., Miles, C. and Grey, H. M. 1987. The relation between major histocompatibility complex (MHC) restriction and the capacity of la to bind Immunogenic peptides. Science 235:1353.
19. Joosten, I., Wauben, M. H. M., Holewijn, M. C., Reske, K., Pedersen, L. O., Roosenboom, C. F. P., Hensen, E. J., van Eden, W. and Buus, S. 1994. Direct binding of autoimmune disease related T cell epitopes to purified Lewis rat MHC class II molecules. Int. Immunol. 6:751.
20. Broeren, C. P. M., Lucassen, M. A., van Stipdonk, M. J. B., van der Zee, R., Boog, C. J. P., Kusters, J. G. and van Eden, W. 1994. CDR1 T-cell receptor beta-chain peptide induces major histocompatibility complex class II-restricted T-T interactions. Proc. Natl Acad. Sci. USA 91:5997.
21. Geluk, A., van Meijgaarden, K. E., Drijfhout, J. W. and Ottenhoff, T. H. M. 1995. CLIP binds to HLA class II using methionine-based, allele-dependent motifs as well as allele-independent supermotifs. Mol. Immunol. 32:975.
22. Ghosh, P., Amaya, M., Mellins, E. and Wiley, D. C. 1995. The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature 378:457.
23. Malcherek, G., Gnau, V., Jung, G., Rammensee, H.-G. and Melms, A. 1995. Supermotifs enable natural invariant-chain derived peptides to interact with many major histocompatibility complexclass II molecules. J. Exp. Med. 181:527.
24. Sette, A., Southwood, S., Miller, J. and Appella, E. 1995. Binding of major histocompatibility complex class II to the invariant-chain derived peptide, CLIP, is regulated by allelic polymorphism in class II. J. Exp. Med. 181:677.
25. Gautam, A. M., Pearson, C., Quinn, V., McDevitt, H. O. and Milburn, P. J. 1995. Binding of an invariant-chain peptide, CLIP, to I-A major histocompatibility complex class II molecules. Proc. Natl Acad. Sci. USA 92:335.
26. Jardetzky, T. S., Gorga, J. C., Busch, R., Rothbard, J., Strominger, J. L. and Wiley D. C. 1990. Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding. EMBO J. 9:1797.
27. Mannie, M. D., Paterson, P. Y., U'Prichard, D. C. and Flouret, G. 1990. The N- and C-terminal boundaries of myelin basic protein determinants required for encephalitogenic and proliferative responses of Lewis rat T cells. J. Neuroimmunol. 26:201.
28. Olee, T., Powers, J. M. and Brostoff, S. W. 1988. A T cell epitope for experimental allergic neuritis. J. Neuroimmunol. 19:167.
29. Kojima, K., Berger, T., Lassmann, H., Hinze-Selch, D., Zhang, Y., Gehrmann, J., Reske, K., Wekerle, H. and Linington, C. 1994. Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100β molecule, a calcium binding protein of astroglia. J. Exp. Med. 180:817.
30. Moticka, E. J. and Adamus, G. 1991 Specificity of T and B cell responses to bovine rhodopsin in Lewis rats. Cell. Immunol. 138:175.
31. Linington, C., Lassmann, H., Ozawa, K., Kosin, S. and Mongan, L. 1992. Cell adhesion molecules of the immunoglobulin supergene family as tissue-specific autoantigens: induction of experimental allergic neuritis (EAN) by PO protein-specific T cell lines. Eur. J. Immunol. 22:1813.
32. van Eden, W., Thole, J., van der Zee, R., Noordzij, A., Embden, J. D. A., Hensen, E. J. and Cohen, I. R., 1988. Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis. Nature 331:171.
33. Fujii, Y. and Lindstrom, J. 1988. Specificity of the T cell immune response to acetylcholine receptor in experimental autoimmune myasthenia gravis. Response to subunits and synthetic peptides. J. Immunol. 140:1830.
34. Wegmann, K. W., Zhao, W., Griffin, A. C. and Hickey, W. F. 1994. Identification of myocarditogenic peptides derived from cardiac myosin capable of inducing experimental allergic myocarditis in the Lewis rat. The utility of a class II binding motif in selecting self-reactive peptides. J. Immunol. 153:892.
35. Zhao, W., Wegmann, K. W., Trotter, J. L., Ueno, K. and Hickey, W. F. 1994. Identification of an N-terminally acetylated encephalitogenic epitope in myelin proteolipid apoprotein for the Lewis rat. J. Immunol. 153:901.
36. Marshall, K. W., Liu, A. F., Canales, J., Perahia, B., Jorgensen, B., Gantzos, R. D., Aguilar, B., Devaux, B. and Rothbard, J. B. 1994. Role of the polymorphic residues in HLA-DR molecules in allele-specific binding of peptide ligands. J. Immunol. 152:4946.
37. Reich, E.-P., von Grafenstein, H., Barlow, A., Swenson, K. E., Williams, K. and C. A. Janeway, Jr. 1994. Self peptides isolated from MHC glycoproteins of non-obese diabetic mice. J. Immunol. 152:2279.
38. Steinmann, L. 1995. Escape from 'Horror Autotoxicus': pathogenesis and treatment of autoimmune disease. Cell 80:7.
39. Johansen, B. H., Vartdal, F., Eriksen, J. A., Thorsby, E. and Sollid, L. M. 1996. Identification of a putative motif for binding of peptides to HLA-DQ2. Int. Immunol. 8:177.
40. Kwok, W. W., Domeier, M. E., Raymond, F. C., Byers, P. and Nepom, G. T. 1996. Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase. J. Immunol. 156:2171.