Effect of okadaic acid on elastin gene expression in interstitial lung fibroblasts

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 271, Issue 6 15-6, 1996, Pages

  Berk, John L ^a,b   Massoomi, Nima ^a   Krupsky, Meir ^a   Goldstein, Ronald H ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Pulmonary Center   (United States)

Author keywords

extracellular matrix; gene transcription; interleukin 1 ; serine threonine protein phosphatase 1 and 2A inhibitor

Indexed keywords

ELASTIN; MESSENGER RNA; OKADAIC ACID;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; LUNG FIBROBLAST; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA ANALYSIS;

EID: 0030444569     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.271.6.l939     Document Type: Article

References (41)

1. Berk, J. L., C. Franzblau, and R. H. Goldstein. Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype. J. Biol. Chem. 266: 3192-3197, 1991.
2. Berk, J. L., R. A. Levine, and R. H. Goldstein. The regulation of elastin gene expression by recombinant interleukin-1β in rat lung fibroblasts (Abstract). Am. Rev. Respir. Dis. 143: A530, 1991.
3. Bialojan, C., and A. Takai. Inhibitory effect of a marine-spong toxin, okadaic acid, on protein phosphatases. Biochem. J. 256: 283-290, 1988.
4. Bonner, W. M., and R. A. Laskey. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. Eur. J. Biochem. 46: 83-88, 1974.
5. Cao, X., R. Mahendran, G. R. Guy, and Y. H. Tan. Protein phosphatase inhibitors induce the sustained expression of the Egr-1 gene and the hyperphosphorylation of its gene product. J. Biol. Chem. 267: 12991-12997, 1992.
6. Cao, Z., W. J. Henzel, and X. Gao. IRAK: a kinase associated with the interleukin-1 receptor. Science Wash. DC 271: 1128-1131, 1996.
7. Chen, C., and H. Okayama. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7: 2745-2752, 1987.
8. Chirgwin, J. M., A. E. Przbyla, R. J. MacDonald, and W. J. Rutter. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18: 5294-5299, 1979.
9. Genovese, C., D. Rowe, and B. Kream. Construction of DNA sequences complementary to rat alpha 1 and alpha 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D. Biochemistry 23: 6210-6216, 1984.
10. Ghosh, S., and D. Baltimore. Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B. Nature Lond. 344: 678-682, 1990.
11. Goldstein, R. H., M. Wall, L. Taylor, M. Cahill, and P. Polgar. Effect of prolonged prostaglandin exposure on prostaglandin synthesis by human lung fibroblasts. Prostaglandins 28: 717-729, 1984.
12. Gray, P. W., E. Glaister, E. Chen, D. V. Goeddel, and D. Pennica. Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta. J. Immunol. 137: 3644-3648, 1986.
13. Greenberg, M. E., and E. B. Ziff. Stimulatino of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature Lond. 311: 433-438, 1984.
14. Groudine, M., M. Peretz, and H. Weintraub. Transcriptional regulation of hemoglobin switching on chicken embryos. Mol. Cell. Biol. 1: 281-288, 1981.
15. Guy, G. R., X. Cao, S. P. Chua, and Y. H. Tan. Okadaic acid mimics multiple changes in early protein phosphorylation and gene expression induced by tumor necrosis factor or interleukin-1. J. Biol. Chem. 267: 1846-1852, 1992.
16. Haystead, T. A., A. T. Sim, D. Carling, R. C. Honnor, Y. Tsukitani, P. Cohen, and D. G. Hardie. Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism. Nature Lond. 337: 78-81, 1989.
17. Heguy, A., C. T. Baldari, G. Macchia, J. L. Telford, and M. Melli. Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction. J. Biol. Chem. 267: 2605-2609, 1992.
18. Herbomel, P., B. Bourachot, and M. Yaniv. Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell 39: 653-659, 1984.
19. Higuchi, M., and B. B. Aggarwal. Okadaic acid induces down-modulation and shedding of tumor necrosis factor receptors. Comparison with another tumor promoter, phorbol ester. J. Biol. Chem. 268: 5624-5631, 1993.
20. Jones, D. T., and R. R. Reed. Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. J. Biol. Chem. 262: 14241-14249, 1987.
21. Kim, I. S., R. W. Park, K. Y. Sohn, and J. S. Jo. Selective inhibition of collagen synthesis by okadaic acid in cultured human fibroblasts. Biochem. Biophys. Res. Commun. 199: 177-182, 1994.
22. Kim, S.-J., K. Y. Kim, S. J. Tapscott, T. S. Winokur, K. Park, H. Fujiki, H. Weintraub, and A. B. Roberts. Inhibition of protein phosphatases blocks myogenesis by first altering MyoD binding activity. J. Biol. Chem. 267: 15140-15145, 1992.
23. Kim, T. A., B. R. Velasquez, and C. E. Wenner. Okadaic acid regulation of the retinoblastoma gene product is correlated with the inhibition of growth factor-induced cell proliferation in mouse fibroblasts. Proc. Natl. Acad. Sci. USA 90: 5460-5463, 1993.
24. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature Lond. 227: 680-685, 1970.
25. Levy, J. P., H. Fujiki, P. Angel, and G. T. Bowden. An inactive mutant response element acts as an active okadaic acid response element in mouse keratinocytes (Abstract). Proc. Am. Assoc. Cancer Res. 32: 297, 1991.
26. Mauviel, A., Y. Q. Chen, V. M. Kahari, I. Ledo, M. Wu, L. Rudnicka, and J. Uitto. Human recombinant interleukin-1 beta up-regulates elastin gene expression in dermal fibroblasts. Evidence for transcriptional regulation in vitro and in vivo. J. Biol. Chem. 268: 6520-6524, 1993.
27. McCroskery, P. A., S. Arai, E. P. Amento, and S. M. Krane. Stimulation of procollagenase synthesis in human rheumatoid synovial fibroblasts by mononuclear cell factor/interleukin 1. FEBS. Lett. 191: 7-12, 1985.
28. Muegge, K., T. M. Williams, J. Kant, M. Karin, R. Chiu, A. Schmidt, U. Siebenlist, H. A. Young, and S. K. Durum. Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1. Science Wash. DC 246: 249-251, 1989.
29. Osborn, L., S. Kunkel, and G. J. Nabel. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc. Natl. Acad. Sci. USA 86: 2336-2340, 1989.
30. Park, K., M. Chung, and S. J. Kim. Inhibition of myogenesis by okadaic acid, an inhibitor of protein phosphatases, 1 and 2A, correlates with the induction of AP1. J. Biol. Chem. 267: 10810-10815, 1992.
31. Parks, W. C., M. E. Kolodziej, and R. A. Pierce. Phorbol ester-mediated downregulation of tropoelastin expression is controlled by a posttranscriptional mechanism. Biochemistry 31: 6639-6645, 1992.
32. Pulverer, B. J., J. M. Kyriakis, J. Avruch, E. Nikolakaki, and J. R. Woodgett. Phosphorylation of c-jun mediated by MAP kinases. Nature Lond. 353: 670-674, 1991.
33. Redpath, N. T., and C. G. Proud. Activity of protein phosphatases against initiation factor-2 and elongation factor-2. Biochem. J. 272: 175-180, 1990.
34. Rich, C. B., and J. A. Foster. Characterization of rat heart tropoelastin. Arch. Biochem. Biophys. 268: 551-558, 1989.
35. Schonthal, A. Okadaic acid - a valuable new tool for the study of signal transduction and cell cycle regulation? New Biol. 4: 16-21, 1992.
36. Stone, P. J., S. M. Morris, B. M. Martin, M. P. McMahon, B. Faris, and C. Franzblau. Repair of protease-damaged elastin in neonatal rat aortic smooth muscle cell cultures. J. Clin. Invest. 82: 1644-1654, 1988.
37. Suganuma, M., H. Fujiki, H. Suguri, S. Yoshizawa, M. Hirota, M. Nakayasu, M. Ojika, K. Wakamatsu, K. Yamada, and T. Sugimura. Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter. Proc. Natl. Acad. Sci. USA 85: 1768-1771, 1988.
38. Sung, S. J., and J. A. Walters. Stimulation of interleukin-1 alpha and interleukin-1 beta production in human monocytes by protein phosphatase 1 and 2A inhibitors. J. Biol. Chem. 268: 5802-5809, 1993.
39. Thevenin, C., S. J. Kim, and J. H. Kehrl. Inhibition of protein phosphatases by okadaic acid induces AP1 in human T cells. J. Biol. Chem. 266: 9363-9366, 1991.
40. Thevenin, C., S. J. Kim, P. Rieckmann, H. Fujiki, M. A. Norcross, M. B. Sporn, A. S. Fauci, and J. H. Kehrl. Induction of nuclear factor-kappa B and the human immunodeficiency virus long terminal repeat by okadaic acid, a specific inhibitor of phosphatases 1 and 2A. New Biol. 2: 793-800, 1990
41. Thomas, P. S. Hybridization of denatured RNA transferred or dotted nitrocellulose paper. Methods Enzymol. 100: 255-266, 1983.