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2 is necessary to keep the macrocycle monomeric.
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2 is necessary to keep the macrocycle monomeric.
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The low reaction temperature (5 °C) was chosen to maximize duplex formation.
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The low reaction temperature (5 °C) was chosen to maximize duplex formation.
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Cleavage at six guanine residues, namely, G5, G7, G9, G24, G26, and G28, was analyzed by gel densitometry. Densitometry measurements involving G30 could not be made accurately.
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61
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Background cleavage was minor, being observed to be less than 2% of the intact substrate strand.
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Background cleavage was minor, being observed to be less than 2% of the intact substrate strand.
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72
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33744712232
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note
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Cleavage at the 5′ end of the substrate may also be attributed to triple helix formation, although this mechanism is not favored; see the text.
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73
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33847483072
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in press.
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2-saturated water is 17.3 ± 1 μs: Sessler, J. L.; Dow, W. C.; O'Connor, D.; Harriman, A.; Hemmi, G.; Mody, T. D.; Miller, R. A.; Qing, F.; Springs, S.; Woodburn, K.; Young, S. W. J. Alloys Compd., in press.
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Sessler, J.L.1
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Hemmi, G.5
Mody, T.D.6
Miller, R.A.7
Qing, F.8
Springs, S.9
Woodburn, K.10
Young, S.W.11
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76
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0000949893
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Pasternack, R.F.1
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Williams, A.F.4
Gibbs, E.J.5
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77
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33744571299
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note
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Poly(A) was used in these studies to illustrate how sapphyrin conjugates might be useful in binding RNA substrates, common single-stranded oligonucleotide therapeutic targets.
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78
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0000685507
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Shionoya, M.; Furuta, H.; Lynch, V.; Harriman, A.; Sessler, J. L. J. Am. Chem. Soc. 1992, 114, 5714-5722.
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Shionoya, M.1
Furuta, H.2
Lynch, V.3
Harriman, A.4
Sessler, J.L.5
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