How are bitter and sweet tastes related?

Trends in Food Science and Technology

Volumn 7, Issue 12, 1996, Pages 399-403

  Walters, D Eric ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030439957     PISSN: 09242244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-2244(96)10040-6     Document Type: Article

References (21)

1. 1 Walters, D.E. and Roy, G. (1996) 'Taste Interactions of Sweet and Bitter Compounds' in Flavor-Food Interactions (McGorrin, R.E. and Leland, J.V., eds), pp. 130-142, American Chemical Society, Washington, DC, USA
2. 2 Lawless, H. (1982) 'Paradoxical Adaptation to Taste Mixtures' in Physiol. Behav. 25, 149-152
3. 3 McBurney, D.H. and Bartoshuk, L.M. (1973) 'Interactions Between Stimuli with Different Taste Qualities' in Physiol. Behav. 10, 1101-1106
4. 4 Muller, C.W. et al. (1992) 'Carboxylic Acid Replacement Structure-Activity Relationships in Suosan Type Sweeteners. A Sweet Taste Antagonist' in J. Med. Chem. 35, 1747-1751
5. 5 Striem, B.J., Pace, U., Zehavi, U., Naim, M. and Lancet, D. (1989) 'Sweet Tastants Stimulate Adenylate Cyclase Coupled to GTP-binding Protein in Rat Tongue Membranes' in Biochem. J. 260, 121-126
6. 6 McLaughlin, S.K., McKinnon, P.J. and Margolskee, R.F. (1992) 'Gustducin is a Taste-cell-specific G Protein Closely Related to the Transducins' in Nature 357, 563-569
7. 7 Price, S. (1973) 'Phosphodiesterase in Tongue Epithelium: Activation by Bitter Taste Stimuli' in Nature 241, 54-55
8. 8 Ruiz-Avila, L. etal. (1995) 'Coupling of Bitter Receptor to Phosphodiesterase Through Transducin in Taste Receptor Cells' in Nature 376, 80-85
9. 9 Akabas, M.H., Dodd, J. and Al-Awqati, Q. (1988) 'A Bitter Substance Induces a Rise in Intracellular Calcium in a Subpopulation of Rat Taste Cells' in Science 242, 1047-1050
10. 10 Hwang, P.M., Verma, A., Bredt, D.S. and Snyder, S.H. (1990) 'Localization of Phosphatidylinositol Signaling Components in Rat Taste Cells: Role in Bitter Taste Transduction' in Proc. Natl. Acad. Sci. U. S. A. 87, 7395-7399
11. 11 Schiffman, S.S. et al. (1994) 'Modulators of the Adenylate Cyclase System Can Alter Electrophysiological Taste Responses in Gerbil' in Pharmacol. Biochem. Behav. 48, 983-990
12. 12 Schiffman, S.S. et al. (1995) 'Effect of Lipid-derived Second Messengers on Electrophysiological Taste Responses in the Gerbil' in Pharmacol. Biochem. Behav. 52, 49-58
13. ++ in Response to Sugars and Non-sugar Sweeteners in Transduction of Sweet Taste in the Rat' in J. Physiol. 490, 325-336
14. 14 Naim, M., Seifert, R., Nürnberg, B., Grünbaum, L. and Schultz, G. (1994) 'Some Taste Substances are Direct Activators of G-proteins' in Biochem. J. 297, 451-454
15. 15 DuBois, G.E., Walters, D.E. and Kellogg, M.S. (1993) 'Mechanism of Human Sweet Taste and Implications for Rational Sweetener Design' in Flavor Measurement (Ho, C-T. and Manley, C.H., eds), pp. 239-266, American Chemical Society, Washington, DC, USA
16. 16 Wong, G.T., Gannon, K.S. and Margolskee, R.F. (1996) 'Transduction of Bitter and Sweet Taste by Gustducin' in Nature 381, 796-800
17. 17 Kinnamon, S.C. (1996) 'A Bitter-sweet Beginning' in Nature 381, 737-738
18. + Current' in J. Neurophysiol. 75, 1256-1263
19. 19 Schiffman, S.S. et al. (1995) 'Investigation of Synergism in Binary Mixtures of Sweeteners' in Brain Res. Bull. 38, 105-120
20. 20 Roy, G. (1992) 'Bitterness: Reduction and Inhibition' in Trends Food Sci. Technol. 3, 85-91
21. 21 Lindley, M.G. (1991) 'Phenoxyalkanoic Acid Sweetness Inhibitors' in Sweeteners: Discovery, Molecular Design, and Chemoreception (Walters, D.E., Orthoefer, F.T. and DuBois, G.E., eds), pp. 251-260, American Chemical Society, Washington, DC, USA