Myocardial protection: The adenosine story

Drug Development Research

Volumn 39, Issue 3-4, 1996, Pages 314-318

  Lasley, Robert D ^a   Mentzer Jr , Robert M ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Adenosine A1 receptors; Cardiac surgery; Myocardial ischemia

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE RECEPTOR STIMULATING AGENT;

CARDIOPLEGIA; CONFERENCE PAPER; DOG; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; NONHUMAN; RABBIT; RAT; SWINE;

EID: 0030437694     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199611/12)39:3/4<314::AID-DDR11>3.0.CO;2-1     Document Type: Conference Paper

References (35)

1. Anchampach JA, Gross GJ (1993): Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs. Am J Physiol 264:H1327-H1336.
2. Dorheim TA, Hoffman A, Van Wylen DGL, Mentzer RM Jr (1991); Enhanced interstitial fluid adenosine attenuates myocardial stunning. Surgery 110:136-145.
3. Ely SW, Mentzer RM Jr, Lasley RD, Lee BK, Berne RM (1985): Functional and metabolic evidence of enhanced myocardial tolerance to ischemia and reperfusion with adenosine. J Thorac Cardiovasc Surg 90:549-556.
4. Fullerton DA, Jones SD Grover FL, McIntyre RC Jr (1996): Adenosine effectively controls pulmonary hypertension alter cardiac operations. Ann Thorac Surg 61:1118-1123.
5. Goto M, Miura T, Iliodoromitis EK, O'Leary EL, Ishimoto R, Yellon DM, Iimura O (1991): Adenosine infusion during early reperfusion failed to limit myocardial infaret size in a collateral deficient species. Cardiovasc Res 25:943-949.
6. Grover GJ, Baird AJ, Sleph PC (1996): Lack of a pharmacologic interaction between ATP-sensitive potassium channels and adenosine A(1) receptors in ischemic rat hearts. Cardiovasc Res 31:511-517.
7. 1 stimulation activates δ protein kinase C in rat ventricular myocytes. Circ Res 78:161-165.
8. Homeister JW, Hoff PT, Fletcher DD, Lucchesi BR (1990): Combined adenosine and lidocaine administration limits myocardial reperfusion injury. Circulation 82:595-608.
9. 1 receptor mechanism. Am J Physiol 263:H1460-H1465.
10. 1 receptor mediated protection of the ischemic rat heart. J Mol Cell Cardiol 25:815-821.
11. 1 receptor mediated protection of the globally ischemic isolated rat heart. J Mol Cell Cardiol 22:39-47.
12. Lasley RD, Anderson CM, Mentzer RM Jr (1993): Ischemic and hypoxic preconditioning enhance postisehemic recovery of function in the rat heart. Cardiovase Res 27:565-570.
13. Lasley RD, Noble MA, Paulsen KL, Mentzer RM Jr (1994): Adenosine attenuates phorbol ester-induced negative inotropic and vaso-constrictive effects in the isolated rat heart. Am J Physiol 266:H2159-H2166.
14. Lasley RD, Konyn PJ, Hegge JO, Mentzer RM Jr (1995a): Effects of ischemic and adenosine preconditioning on interstitial fluid adenosine and myocardial infarct size. Am J Physiol 269:H1460-H1466.
15. Lasley RD, Noble MA, Konyn PJ, Mentzer RM (1995b): Different effects of an adenosine A(1) analogue and ischemic preconditioning in isolated rabbit hearts. Ann Thorac Surg 60:1698-1703.
16. Lee HT, Lafaro RJ, Reed GE (1995): Pretreatment of human myocardium with adenosine during open heart surgery. J Cardiac Surg 10:665-676.
17. Li Y, Kloner RA (1993): The cardioprotective effects of ischemic preconditioning are not mediated by adenosine receptors in rat hearts. Circulation 87:1642-1648.
18. Liu GS, Jacobson KA, Downey JM (1996): An irreversible A(1) selec-live adenosine agonist preconditions rabbit heart. Can J Cardiol 12:517-521.
19. Martin BJ, Lasley RD, Mentzer RM Jr (1996): Infarct size reduction with the nucleoside transport inhibitor R75231 in swine. Am J Physiol (in press).
20. Matsuoka H, Henrichs KJ, Schaper W (1985): Influence of dipyridamole on infarct size and on cardiac nucleotide content following coronary occlusion in the dog. Basic Res Cardiol 80:682-692.
21. McClanahan TB, Ignasiak DP, Martin BJ, Mertz TE, Gallagher KP (1995): Effect of adenosine deaminase inhibition with pentostatin on myocardial stunning in dogs. Basic Res Cardiol 90:176-183.
22. Mentzer RM Jr, Canver CC, Chopra PS, Love RB, Rahko PS, Hegge JO, Lasley RD (1995): Efficacy of adenosine as an additive to blood cardioplegia in humans during open-heart surgery. Circulation 92 (Suppl I):I-762.
23. Murry CE, Jennings RB, Reimer KA (1986): Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium. Circulation 74:1124-1136.
24. Olafsson B, Forman MB, Puett DW, Pou A, Cates CU, Friesinger GC, Virmani R (1987): Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: Importance of the endothelium and the no-reflow phenomenon. Circulation 76:1135-1145.
25. Owall A, Ehrenberg J, Brodin LA, Juhlin-Dannfelt A, Sollevi A (1993): effects of low-dose adenosine on myocardial performance after coronary artery bypass surgery. Acta Anaesthesiol Scand 37:140-148.
26. Randhawa MPS Jr, Lasley RD, Mentzer RM Jr (1995): Salutary effects of exogenous adenosine on canine myocardial stunning in vivo. J Thorac Cardiovasc Surg 110:63-74.
27. Silva PH, Dillon D, Van Wylen DG (1995): Adenosine deaminase in-hibition augments interstitial adenosine but does not attenuate myocardial infarction. Cardiovasc Res 29:616-623.
28. Thornton JD, Liu GS, Olsson RA, Downey JM (1992): Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation 85:659-665.
29. Van Wylen DGL, Willis J, Sodhi J, Weiss RJ, Lasley RD, Mentzer RM (1990): Cardiac microdialysis to estimate interstitial adenosine and coronary blood flow. Am J Physiol 258:H1642-H1649
30. ATP channel antagonist to attenuate preconditioning in rabbit myocardium. Cardiovasc Res 28:1337-1341.
31. Wyatt DA, Ely SW, Lasley RD, Walsh R, Mainwaring R, Berne RM, Mentzer RM (1989): Purine-enhanced asanguineous cardioplegia retards adenosine triphosphate degradation during ischemia and improves postischemic ventricular Function. J Thorac Cardiovasc Surg 97:771-778.
32. Xu J, Wang L, Hurt CM, Pelleg A (1994): Endogenous adenosine does not activate ATP-sensitive potassium channels in the hypoxic guinea pig ventricle in vivo. Circulation 89:1209-1216.
33. Yao Z, Gross CJ (1993): Glibenclamide antagonizes adenosine A1 receptor-mediated cardioprotection in stunned canine myocardium. Circulation 88:235-244.
34. Ytrehus K, Liu Y, Downey JM (1994): Preconditioning protects ischemic rabbit heart by protein kinase C activation Am J Physiol 266:H1145-H1152.
35. Zhou Z, Bünger R, Lasley RD, Hegge JO, Mentzer RM Jr (1993): Adenosine pretreatment increases cytosolic phosphorylation potential and attenuates postischemic cardiac dysfunction in swine. Surg Forum 44:249-252.