Adenosine effectively controls pulmonary hypertension after cardiac operations

Annals of Thoracic Surgery

Volumn 61, Issue 4, 1996, Pages 1118-1124

  Fullerton, David A ^a,b   Jones, Stephen D ^a   Grover, Frederick L ^a   McIntyre Jr , Robert C ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; VASODILATOR AGENT;

AGED; ARTICLE; CLINICAL TRIAL; DRUG EFFECT; HEART RIGHT VENTRICLE FUNCTION; HEART SURGERY; HEMODYNAMICS; HUMAN; METHODOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; PATIENT MONITORING; PEROPERATIVE CARE; PEROPERATIVE COMPLICATION; PULMONARY HYPERTENSION; STATISTICS;

ADENOSINE; AGED; CARDIAC SURGICAL PROCEDURES; HEMODYNAMIC PROCESSES; HUMANS; HYPERTENSION, PULMONARY; INTRAOPERATIVE CARE; INTRAOPERATIVE COMPLICATIONS; MIDDLE AGED; MONITORING, INTRAOPERATIVE; VASODILATOR AGENTS; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 0038975196     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/0003-4975(95)01149-8     Document Type: Article

References (24)

1. Packer M, Greenberg B, Massie B, Dash H. Deleterious effects of hydralazine in patients with pulmonary hypertension. N Engl J Med 1982;306:1326-31.
2. Fullerton DA, Hahn AR, Banerjee A, Harken AH. Pulmonary vascular smooth muscle relaxation by cGMP-versus cAMP-mediated mechanisms. J Surg Res 1994;57:259-63.
3. Fullerton DA, Agrafojo J, McIntyre RC Jr. Pulmonary vascular smooth muscle relaxation by cAMP-mediated mechanisms. J Surg Res (in press).
4. Berne RM. The role of adenosine in the regulation of coronary blood flow. Circ Res 1980;47:807-13.
5. Klabunde RE. Dipyridamole inhibition of adenosine metabolism in human blood. Eur J Pharmacol 1983;93:21-6.
6. Mentzer RM Jr, Rubio R, Berne RM. Release of adenosine by hypoxic canine lung tissue and its possible role in pulmonary circulation. Am J Physiol 1975;229:1625-31.
7. Neely CF, Kadowitz PJ, Lippton H, Neiman M, Hyman AL. Adenosine does not mediate the pulmonary vasodilator response of adenosine 5′-triphosphate in the feline pulmonary vascular bed. J Pharmacol Exp Ther 1989;250:170-6.
8. Catravas JD. Removal of adenosine from the rabbit pulmonary circulation in vivo and in vitro. Circ Res 1984;54:603-11.
9. Utterback DB, Staples ED, White SE, Hill JA, Belardinelli L. Basis for the selective reduction of pulmonary vascular resistance in humans during infusion of adenosine. J Appl Physiol 1994;76:724-30.
10. McCormack DG, Clarke B, Barnes PJ. Characterization of adenosine receptors in human pulmonary arteries. Am J Physiol 1989;256:H41-6.
11. Morgan JM, McCormack DG, Griffiths MJD, Morgan BM, Barnes PJ, Evans TW. Adenosine as a vasodilator in primary pulmonary hypertension. Circulation 1991;84:1145-9.
12. Schrader B, Inbar S, Kaufman L, Vestal RE, Rich S. Comparison of the effects of adenosine and nifedipine in pulmonary hypertension. J Am Coll Cardiol 1992;19:1060-4.
13. Fullerton DA, Kirson LE, Jones SD, McIntyre RC Jr. Adenosine is a selective pulmonary vasodilator in cardiac surgical patients. Chest 1996;109:41-6.
14. 2 on pulmonary vascular resistance following cardiac surgery. J Thorac Cardiovasc Surg 1993;106:528-36.
15. Grossman W, Alpert JS, Braunwald E. Pulmonary hypertension. In: Braunwald E, ed. Heart disease, a textbook of cardiovascular medicine. 2nd ed. Philadelphia: Saunders, 1984:830-1.
16. Edlund A, Sollevi A, Linde B. Haemodynamic and metabolic effects of infused adenosine in man. Clin Sci 1990;79:131-8.
17. Bush A, Busst CM, Clarke B, Barnes PJ. Effect of infused adenosine on cardiac output and systemic resistance in normal subjects. Br J Clin Pharmacol 1989;27:165-71.
18. Fuller RW, Maxwell DL, Conradson T-BG, Dixon CMS, Barnew PJ. Circulatory and respiratory effects of infused adenosine in conscious man. Br J Clin Pharmacol 1987;92: 789-94.
19. Öwall A, Gordon E, Lagerkranser M, Lindquist C, Rudehill A, Sollevi A. Clinical experience with adenosine for controlled hypotension during cerebral aneurysm surgery. Anesth Analg 1987;66:229-34.
20. Öwall A, Järnberg P-O, Brodin L-Å, Sollevi A. Effects of adenosine-induced hypotension on myocardial hemodynamics and metabolism in fentanyl anesthetized patients with peripheral vascular disease. Anesthesiology 1988;68: 416-21.
21. Fullerton DA, Jones SD, Jaggers J, Piedalue F, Grover FL, McIntyre RC Jr. Effective control of pulmonary vascular resistance with inhaled nitric oxide following cardiac operation. J Thorac Cardiovasc Surg (in press).
22. Vlahakes GJ, Turley K, Hoffman JIE. The pathophysiology of failure in acute right ventricular hypertension: hemodynamic and biochemical correlations. Circulation 1981;63: 87-95.
23. Haywood GA, Sneddon JF, Bashir Y, Jennison SH, Gray HH, McKenna WJ. Adenosine infusion for the reversal of pulmonary vasoconstriction in biventricular failure: a good test but a poor therapy. Circulation 1992;86:896-902.
24. Nussbacher A, Sigmituzo A, Kalil R, et al. Mechanism of adenosine-induced elevation of pulmonary capillary wedge pressure in humans. Circulation 1995;92:371-9.