Zinc neurotoxicity may contribute to selective neuronal death following transient global cerebral ischemia

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 61, Issue , 1996, Pages 385-387

  Choi, D W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; ZINC;

ANIMAL CELL; BRAIN ISCHEMIA; CALCIUM TRANSPORT; CELL DEATH; CHANNEL GATING; CONFERENCE PAPER; HIPPOCAMPUS; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; ZINC METABOLISM; ARTICLE; HUMAN;

ANIMALIA;

EID: 0030428903     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.1996.061.01.041     Document Type: Conference Paper

References (23)

1. ++ from brain tissue during activity. Nature 308: 734.
2. Choi, D.W., M. Yokoyama, and J. Koh. 1988. Zinc neurotoxicity in cortical cell culture. Neuroscience 24: 67.
3. Christine, C.W. and D.W. Choi. 1990. Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons. J. Neurosci. 10: 108.
4. Frederickson, C.J., 1989. Neurobiology of zinc and zinc-containing neurons. Int. Rev. Neurobiol. 131: 145.
5. Frederickson, C.J., B.A. Rampy, S. Reamy-Rampy, and G.A. Howell. 1992. Distribution of histochemically reactive zinc in the forebrain of the rat. J. Chem. Neuroanal. 5: 521.
6. Frederickson, C.J., M.D. Hernandez, S.A. Goik, J.D. Morton, and J.F. McGinty. 1988. Loss of zinc staining from hippocampal mossy fibers during kainic acid induced seizures: A histofluorescence study. Brain Res 446: 383.
7. Goto, K., A. Ishige, K. Sekiguchi, S. Iizuka, A. Sugimoto, M. Yuzurihara, M. Aburada, E. Hosoya, and K. Kogure. 1990. Effects of cycioheximide on delayed neuronal death in rat hippocampus. Brain Res. 534: 299.
8. Héron, A., H. Pollard, F. Dessi, J. Moreau, F. Lasbennes, Y. Ben-Ari, and C. Charriaut-Marlangue. 1993. Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain. J. Neurochem. 61: 1973.
9. Koh, J.Y. and D.W. Choi. 1988 Zinc alters excitatory amino acid neurotoxicity on cortical neurons. J. Neurosci. 8: 2164.
10. _, 1994. Zinc toxicity on cultured cortical neurons: Involvement on N-methyt-δ-aspartate receptors. Neuroscience 60: 1049.
11. Koh, J.Y., S.W. Suh, B.J. Gwag, Y.Y. He, C.Y. Hsu, and D.W. Choi. 1996. The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 272: 1013.
12. MacManus, J.P., A.M. Buchan, I.E. Hill, I. Rasquinha, and E. Preston. 1993. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci. Lett. 164: 89.
13. Nitatori, T., N. Sato, S. Waguri, Y. Karasawa, H. Araki, K. Shibanai, E. Kominami, and Y. Uchiyama. 1995. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci 15: 1001.
14. Okamoto, M., M. Matsumoto, T. Ohtsuki, A. Taguchi, K. Mikoshiba, T. Yanagihara, and T. Kamada. 1993. Internucleosomal DNA cleavage involved in ischemia-induced neuronal death. Biochem. Biophys. Res. Commun. 196: 1356.
15. Palmiter, R.D. and S.D. Findley. 1995. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J. 14: 639.
16. Peters, S., J. Koh, and D.W. Choi. 1987. Zinc selectively blocks the action of N-methyl-δ-aspartate on cortical neurons. Science 236: 589.
17. Shigeno, T., Y. Yamasaki, G. Kato, K. Kusaka, T. Mima, K. Takakura, D.I. Graham, and S. Furukawa. 1990. Reduction of delayed neuronal death by inhibition of protein synthesis. Neurosci. Lett. 120: 117.
18. Sloviter, R.S., 1985. A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation. Brain Res. 330: 150.
19. Smart, T.G., X. Xie, and B.J. Krishek. 1994. Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc. Prog. Neurobiol. 42: 393.
20. Tonder, N., F.F. Johansen, C.J. Frederickson, J. Zimmer, and N.H. Diemer. 1990. Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. Neurosci. Lett. 109: 247.
21. Weiss, J.H., D.M. Hartley, J.Y. Koh, and D.W. Choi. 1993. AMPA receptor activation potentiates zinc neurotoxicity. Neuron 10: 43.
22. ++ antagonize NMDA and GABA responses of hippocampal neurons. Nature 328:640.
23. 2+ permeable AMPA/kainate channels display distinct receptor immunoreactivity and are GABAergic. Neurobiol. Dis. 1: 43.