메뉴 건너뛰기




Volumn 7, Issue 6, 1996, Pages 309-315

The disruption of cell cycle checkpoints by papillomavirus oncoproteins contributes to anogenital neoplasia

Author keywords

Cell cycle; Checkpoints; E6; E7; Neoplasia

Indexed keywords

DNA; ONCOPROTEIN; VIRUS PROTEIN;

EID: 0030391326     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1006/scbi.1996.0040     Document Type: Review
Times cited : (70)

References (49)
  • 1
    • 0025886714 scopus 로고
    • Human papillomaviruses in the pathogenesis of anogenital cancer
    • 1. zur Hausen H (1991) Human papillomaviruses in the pathogenesis of anogenital cancer. Virology 184:9-13
    • (1991) Virology , vol.184 , pp. 9-13
    • Zur Hausen, H.1
  • 2
    • 0028220897 scopus 로고
    • Immortalization and transformation of human cells by human papillomavirus
    • 2. McDougall JK (1994) Immortalization and transformation of human cells by human papillomavirus. Curr Top Microbiol Immunol 186:101-119
    • (1994) Curr Top Microbiol Immunol , vol.186 , pp. 101-119
    • McDougall, J.K.1
  • 3
    • 0026680249 scopus 로고
    • The two-stage mechanism controlling cellular senescence and immortalization
    • 3. Wright WE, Shay JW (1992) The two-stage mechanism controlling cellular senescence and immortalization. Exp Gerontol 27:383-389
    • (1992) Exp Gerontol , vol.27 , pp. 383-389
    • Wright, W.E.1    Shay, J.W.2
  • 4
    • 0002092675 scopus 로고    scopus 로고
    • Use of amphotropic retroviruses expressing HPV 16 E6 and E7 to determine the consequences of acute expression of the viral oncogenes and to establish immortalized human cell lines
    • 4. Galloway DA, Halbert CL, Demers GW, Foster SA, Blanton RA, Merrick D, Klingelhutz A, McDougall JK (1996) Use of amphotropic retroviruses expressing HPV 16 E6 and E7 to determine the consequences of acute expression of the viral oncogenes and to establish immortalized human cell lines. Radiat Oncol Invest 3:315-319
    • (1996) Radiat Oncol Invest , vol.3 , pp. 315-319
    • Galloway, D.A.1    Halbert, C.L.2    Demers, G.W.3    Foster, S.A.4    Blanton, R.A.5    Merrick, D.6    Klingelhutz, A.7    McDougall, J.K.8
  • 6
    • 0027315211 scopus 로고
    • Interaction of HPV-18 and nitrosomethylurea in the induction of squamous cell carcinoma
    • 6. Garrett LR, Perez-Reyes N, Smith PP, McDougall JK (1993) Interaction of HPV-18 and nitrosomethylurea in the induction of squamous cell carcinoma. Carcinogenesis 14:329-332
    • (1993) Carcinogenesis , vol.14 , pp. 329-332
    • Garrett, L.R.1    Perez-Reyes, N.2    Smith, P.P.3    McDougall, J.K.4
  • 7
    • 0026024632 scopus 로고
    • The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells
    • 7. Halbert CL, Demers GW, Galloway DA (1991) The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells. J Virol 65:473-478
    • (1991) J Virol , vol.65 , pp. 473-478
    • Halbert, C.L.1    Demers, G.W.2    Galloway, D.A.3
  • 8
    • 0026950853 scopus 로고
    • Expression of the HPV16 E7 gene generates proliferation in stratified squamous cell cultures which is independent of endogenous p53 levels
    • 8. Blanton RA, Coltrera MD, Gown AM, Halbert CL, McDougall JK (1992) Expression of the HPV16 E7 gene generates proliferation in stratified squamous cell cultures which is independent of endogenous p53 levels. Cell Growth Diff 3:791-802
    • (1992) Cell Growth Diff , vol.3 , pp. 791-802
    • Blanton, R.A.1    Coltrera, M.D.2    Gown, A.M.3    Halbert, C.L.4    McDougall, J.K.5
  • 9
    • 0026609366 scopus 로고
    • The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells
    • 9. Halbert CL, Demers GW, Galloway DA (1992) The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells. J Virol 66:2125-2134
    • (1992) J Virol , vol.66 , pp. 2125-2134
    • Halbert, C.L.1    Demers, G.W.2    Galloway, D.A.3
  • 10
  • 11
    • 0028986639 scopus 로고
    • cip1 in muscle and other terminally differentiating cells
    • cip1 in muscle and other terminally differentiating cells. Science 267:1024-1027
    • (1995) Science , vol.267 , pp. 1024-1027
    • Parker, S.B.1    Eichele, G.2    Zhang, P.3
  • 12
    • 0028978183 scopus 로고
    • Mice lacking P21 (C/P1/WAF1) undergo normal development, but are defective in G1 checkpoint control
    • 12. Deng CX, Zhang PM, Harper JW, Elledge SJ, Leder P (1995) Mice lacking P21 (C/P1/WAF1) undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.X.1    Zhang, P.M.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 13
    • 0028913739 scopus 로고
    • A p53-dependent mouse spindle checkpoint
    • 13. Cross SM, Sanchez CA, Morgan CA, et al (1995) A p53-dependent mouse spindle checkpoint. Science 267:1353-1356
    • (1995) Science , vol.267 , pp. 1353-1356
    • Cross, S.M.1    Sanchez, C.A.2    Morgan, C.A.3
  • 14
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • 14. Waldman T, Lengauer C, Kinzler KW, Vogelstein B (1996) Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381:713-716
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 15
    • 0026601249 scopus 로고
    • Altered expression of proliferation and differentiation markers in human papillomavirus 16 and 18 immortalized epithelial cells grown in organotypic culture
    • 15. Merrick DT, Blanton RA, Gown AM, McDougall JK (1992) Altered expression of proliferation and differentiation markers in human papillomavirus 16 and 18 immortalized epithelial cells grown in organotypic culture. Am J Pathol 140:167-177
    • (1992) Am J Pathol , vol.140 , pp. 167-177
    • Merrick, D.T.1    Blanton, R.A.2    Gown, A.M.3    McDougall, J.K.4
  • 16
    • 0026452949 scopus 로고
    • Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
    • 16. Hartwell LH (1992) Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71:543-546
    • (1992) Cell , vol.71 , pp. 543-546
    • Hartwell, L.H.1
  • 19
  • 21
    • 0028985945 scopus 로고
    • Defective G2 checkpoint function in cells from individuals with familial cancer syndromes
    • 21. Paules RS, Levedakou EN, Wilson SJ, et al (1995) Defective G2 checkpoint function in cells from individuals with familial cancer syndromes. Cancer Res 55:1763-1773
    • (1995) Cancer Res , vol.55 , pp. 1763-1773
    • Paules, R.S.1    Levedakou, E.N.2    Wilson, S.J.3
  • 23
    • 0029781222 scopus 로고    scopus 로고
    • Interaction of cyclin-dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine
    • 23. Yuan ZM, Huang Y, Kraeft SK, Chen LB, Kharbanda S, Kufe D (1996) Interaction of cyclin-dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine. Oncogene 13:939-946
    • (1996) Oncogene , vol.13 , pp. 939-946
    • Yuan, Z.M.1    Huang, Y.2    Kraeft, S.K.3    Chen, L.B.4    Kharbanda, S.5    Kufe, D.6
  • 24
    • 0029028584 scopus 로고
    • Evidence for a NIMA-like mitotic path way in vertebrate cells
    • 24. Lu KP, Hunter T (1995) Evidence for a NIMA-like mitotic path way in vertebrate cells. Cell 81:413424
    • (1995) Cell , vol.81 , pp. 413424
    • Lu, K.P.1    Hunter, T.2
  • 25
    • 0029670589 scopus 로고    scopus 로고
    • p53 in signaling checkpoint arrest or apoptosis
    • 25. Bates S, Vousden KH (1996) p53 in signaling checkpoint arrest or apoptosis. Curr Opin Genet Dev 6:12-18
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 12-18
    • Bates, S.1    Vousden, K.H.2
  • 26
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • 26. Demers GW, Foster SA, Halbert CL, Galloway DA (1994) Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc Natl Acad Sci USA 91:43824386
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 43824386
    • Demers, G.W.1    Foster, S.A.2    Halbert, C.L.3    Galloway, D.A.4
  • 27
    • 0027266971 scopus 로고
    • Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage
    • 27. Kessis TD, Slebos RJ, Nelson WG, et al (1993) Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc Natl Acad Sci USA 90:3988-3992
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3988-3992
    • Kessis, T.D.1    Slebos, R.J.2    Nelson, W.G.3
  • 28
    • 0027941170 scopus 로고
    • The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest
    • 28. Foster SA, Demers GW, Etscheid BG, Galloway DA (1994) The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. J Virol 68:5698-5705
    • (1994) J Virol , vol.68 , pp. 5698-5705
    • Foster, S.A.1    Demers, G.W.2    Etscheid, B.G.3    Galloway, D.A.4
  • 29
    • 0028177401 scopus 로고
    • p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein
    • 29. Slebos RJ, Lee MH, Plunkett BS, et al (1994) p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc Natl Acad Sci USA 91:5320-5324
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5320-5324
    • Slebos, R.J.1    Lee, M.H.2    Plunkett, B.S.3
  • 30
    • 0028239976 scopus 로고
    • Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation
    • 30. Hickman ES, Picksley SM, Vousden KH (1994) Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. Oncogene 9:2177-2181
    • (1994) Oncogene , vol.9 , pp. 2177-2181
    • Hickman, E.S.1    Picksley, S.M.2    Vousden, K.H.3
  • 32
    • 0029583648 scopus 로고
    • Regulation of the cyclin E gene by transcription factor E2F1
    • 32. Ohtani K, DeGregori J, Nevins JR (1995) Regulation of the cyclin E gene by transcription factor E2F1. Proc Natl Acad Sci USA 92:12146-12150
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12146-12150
    • Ohtani, K.1    DeGregori, J.2    Nevins, J.R.3
  • 33
    • 0029986337 scopus 로고    scopus 로고
    • Regulation of cyclin E transcription by E2Fs and retinoblastoma protein
    • 33. Geng Y, Eaton EN, Picon M, et al (1996) Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 12:1173-1180
    • (1996) Oncogene , vol.12 , pp. 1173-1180
    • Geng, Y.1    Eaton, E.N.2    Picon, M.3
  • 35
    • 0029134617 scopus 로고
    • Sequential activation of cyclin E and cyclin a gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation
    • 35. Zerfass K, Schulze A, Spitkovsky D, Friedman V, Henglein B, Jansen-Durr P (1995) Sequential activation of cyclin E and cyclin a gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation. J virol 69:6389-6389
    • (1995) J Virol , vol.69 , pp. 6389-6389
    • Zerfass, K.1    Schulze, A.2    Spitkovsky, D.3    Friedman, V.4    Henglein, B.5    Jansen-Durr, P.6
  • 36
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • 36. Zhang H, Hannon GJ, Beach D (1995) p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 8:1750-1758
    • (1995) Genes Dev , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3
  • 37
    • 0029815035 scopus 로고    scopus 로고
    • Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation
    • 37. Demers GW, Espling E, Harry JB, Etscheid BG, Galloway DA (1996) Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation. J Virol 70:6862-6869
    • (1996) J Virol , vol.70 , pp. 6862-6869
    • Demers, G.W.1    Espling, E.2    Harry, J.B.3    Etscheid, B.G.4    Galloway, D.A.5
  • 38
    • 0029670376 scopus 로고    scopus 로고
    • Inactivation of p27Kip 1 by the viral E1a oncoprotein in TGFbeta-treated cells
    • 38. Mal A, Poon RY, Howe PH, Toyoshima H, Hunter T, Harter ML (1996) Inactivation of p27Kip 1 by the viral E1A oncoprotein in TGFbeta-treated cells. Nature 380:262-265
    • (1996) Nature , vol.380 , pp. 262-265
    • Mal, A.1    Poon, R.Y.2    Howe, P.H.3    Toyoshima, H.4    Hunter, T.5    Harter, M.L.6
  • 39
    • 0030443870 scopus 로고    scopus 로고
    • Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein
    • 39. Zerfass-Thome K, Zwerschke W, Mannhardt B, Tindle R, Botz JW, Jansen-Durr P (1996) Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein. Oncogene 13:2323-2330
    • (1996) Oncogene , vol.13 , pp. 2323-2330
    • Zerfass-Thome, K.1    Zwerschke, W.2    Mannhardt, B.3    Tindle, R.4    Botz, J.W.5    Jansen-Durr, P.6
  • 40
    • 0028140264 scopus 로고
    • Restoration of telomeres in human papillomavirus-immortalized human anogenital cells
    • 40. Klingelhutz AJ, Barber SA, Smith PP, Dyer K, McDougall JK (1994) Restoration of telomeres in human papillomavirus-immortalized human anogenital cells. Mol Cell Biol 14:961-969
    • (1994) Mol Cell Biol , vol.14 , pp. 961-969
    • Klingelhutz, A.J.1    Barber, S.A.2    Smith, P.P.3    Dyer, K.4    McDougall, J.K.5
  • 41
    • 0028331229 scopus 로고
    • Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
    • 41. White AE, Livanos EM, Tlsty TD (1994) Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev 8:666-677
    • (1994) Genes Dev , vol.8 , pp. 666-677
    • White, A.E.1    Livanos, E.M.2    Tlsty, T.D.3
  • 42
    • 0024810844 scopus 로고
    • Cytogenetic analysis of eight human papillomavirus immortalized human keratinocyte cell lines
    • 42. Smith PP, Bryant EM, Kaur P, McDougall JK (1989) Cytogenetic analysis of eight human papillomavirus immortalized human keratinocyte cell lines. Int J Cancer 44:1124-1131
    • (1989) Int J Cancer , vol.44 , pp. 1124-1131
    • Smith, P.P.1    Bryant, E.M.2    Kaur, P.3    McDougall, J.K.4
  • 43
    • 0029111826 scopus 로고
    • Genetic instability of chromosome 3 in HPV-immortalized and tumorigenic human keratinocytes
    • 43. Montgomery KD, Tedford KL, McDougall JK (1995) Genetic instability of chromosome 3 in HPV-immortalized and tumorigenic human keratinocytes. Genes, Chromosomes Cancer 14:97-105
    • (1995) Genes, Chromosomes Cancer , vol.14 , pp. 97-105
    • Montgomery, K.D.1    Tedford, K.L.2    McDougall, J.K.3
  • 44
    • 0030069586 scopus 로고    scopus 로고
    • Genomic alterations in cervical carcinoma: Losses of chromosome heterozygosity and human papilloma virus tumor status
    • 44. Mullokandov MR, Kholodilov NG, Atkin NB, Burk RD, Johnson AB, Klinger HP (1996) Genomic alterations in cervical carcinoma: losses of chromosome heterozygosity and human papilloma virus tumor status. Cancer Res 56:197-205
    • (1996) Cancer Res , vol.56 , pp. 197-205
    • Mullokandov, M.R.1    Kholodilov, N.G.2    Atkin, N.B.3    Burk, R.D.4    Johnson, A.B.5    Klinger, H.P.6
  • 45
    • 0030068216 scopus 로고    scopus 로고
    • Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix
    • 45. Heselmeyer K, Schrock E, du Manoir S, et al (1996) Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix. Proc Natl Acad Sci USA 93:479484
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 479484
    • Heselmeyer, K.1    Schrock, E.2    Du Manoir, S.3
  • 46
    • 0027401117 scopus 로고
    • Alteration of the DCC tumor-suppressor gene in tumorigenic HPV-18 immortalized human keratinocytes transformed by nitrosomethylurea
    • 46. Klingelhutz AJ, Smith PP, Garrett LR, McDougall JK (1993) Alteration of the DCC tumor-suppressor gene in tumorigenic HPV-18 immortalized human keratinocytes transformed by nitrosomethylurea. Oncogene 8:95-99
    • (1993) Oncogene , vol.8 , pp. 95-99
    • Klingelhutz, A.J.1    Smith, P.P.2    Garrett, L.R.3    McDougall, J.K.4
  • 47
    • 0029027344 scopus 로고
    • The DCC gene suppresses the malignant phenotype of transformed human epithelial cells
    • 47. Klingelhutz AJ, Hedrick L, Cho KR, McDougall JK (1995) The DCC gene suppresses the malignant phenotype of transformed human epithelial cells. Oncogene 10:1581-1586
    • (1995) Oncogene , vol.10 , pp. 1581-1586
    • Klingelhutz, A.J.1    Hedrick, L.2    Cho, K.R.3    McDougall, J.K.4
  • 48
    • 0029852617 scopus 로고    scopus 로고
    • Re-expression of interleukin 1 in human papillomavirus 18 immortalized keratinocytes inhibits their tumorigenicity in nude mice
    • 48. Merrick DT, Winberg G, McDougall JK (1997) Re-expression of interleukin 1 in human papillomavirus 18 immortalized keratinocytes inhibits their tumorigenicity in nude mice. Cell Growth Differ 7:1661-1669
    • (1997) Cell Growth Differ , vol.7 , pp. 1661-1669
    • Merrick, D.T.1    Winberg, G.2    McDougall, J.K.3
  • 49
    • 0001951359 scopus 로고    scopus 로고
    • Epidemiology and modes of transmission
    • (vonKrogh G, Gross G, eds) CRC Press, Boca Raton, FL
    • 49. Shoultz DA, Koutsky LA, Galloway DA (1997) Epidemiology and modes of transmission, in Human Papilloma Viruses (vonKrogh G, Gross G, eds) pp 83-97. CRC Press, Boca Raton, FL
    • (1997) Human Papilloma Viruses , pp. 83-97
    • Shoultz, D.A.1    Koutsky, L.A.2    Galloway, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.