Characterization of a Novel Arginine/Serine-Rich Splicing Factor in Arabidopsis

Plant Cell

Volumn 8, Issue 12, 1996, Pages 2255-2264

  Lopato, Sergiy ^a   Waigmann, Elisabeth ^a   Barta, Andrea ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; ARABIDOPSIS; VERTEBRATA;

ARABIDOPSIS PROTEIN; ARGININE; NUCLEAR PROTEIN; RECOMBINANT PROTEIN; RNA BINDING PROTEIN; RNA PRECURSOR; RSP31 PROTEIN, ARABIDOPSIS; SERINE; VEGETABLE PROTEIN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; CELL NUCLEUS; CHEMISTRY; COMPARATIVE STUDY; COMPUTER PROGRAM; GENETICS; HELA CELL; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS PROTEINS; ARGININE; BASE SEQUENCE; CELL NUCLEUS; CLONING, MOLECULAR; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PLANT PROTEINS; RECOMBINANT PROTEINS; RNA PRECURSORS; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SOFTWARE;

EID: 0030337963     PISSN: 10404651     EISSN: None     Source Type: Journal    
DOI: 10.1105/tpc.8.12.2255     Document Type: Article

References (62)

1. Amrein, H., Gorman, M., and Nothiger, R. (1988). The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein Cell 55, 1025-1035 Erratum. Cell 58, 419
2. Amrein, H., Hedley, M.L., and Maniatis, T. (1994). The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2. Cell 76, 735-746.
3. Baker, B.S. (1989). Sex in flies: The splice of life. Nature 340, 521-524.
4. Barta, A., Sommergruber, K., Thompson, D., Hartmuth, K., Matzke, M.A., and Matzke, A.J.M. (1986). The expression of a nopaline synthase - Human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue. Plant Mol. Biol. 6, 347-357.
5. Birney, E., Kumar, S., and Krainer, A.R. (1993) Analysis of the RNA-recognition motif and RS and RGG domains: Conservation in metazoan pre-mRNA splicing factors Nucleic Acids Res. 21, 5803-5816.
6. Boggs, R.T., Gregor, P., Idriss, S., Belote, J.M., and McKeown, M. (1987). Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell 50, 739-747
7. Brown, J.W., Feix, G., and Frendewey, D. (1986). Accurate in vitro splicing of two pre-mRNA plant introns in a HeLa cell nuclear extract. EMBO J. 5, 2749-2758.
8. Caceres, J.F., Stamm, S., Helfman, D.M., and Krainer, A.R. (1994). Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science 265, 1706-1709.
9. Cardinali, B., Cohen, P.T., and Lamond, A.I. (1994). Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract. FEBS Lett. 352, 276-280.
10. Cavaloc, Y., Popielarz, M., Fuchs, J.P., Gattoni, R., and Stevenin, J. (1994). Characterization and cloning of the human splicing factor 9G8: A novel 35 kDa factor of the serine/arginine protein family EMBO J 13, 2639-2649.
11. Chou, T.B., Zachar, Z., and Bingham, P.M. (1987). Developmental expression of a regulatory gene is programmed at the level of splicing EMBO J. 6, 4095-4104.
12. Colwill, K., Pawson, T., Andrews, B., Prasad, J., Manley, J.L., Bell, J.C., and Duncan, P.I. (1996) The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intracellular distribution. EMBO J. 15, 265-275
13. Filipowicz, W., Gniadkowski, M., Klahre, U., and Liu, H.-X. (1995). Pre-mRNA splicing in plants In Pre-mRNA Processing, A. Lamond, ed (Georgetown, TX: R.G. Landes Publishers), pp. 66-77.
14. Fu, X.-D. (1993) Specific commitment of different pre-mRNAs to splicing by single SR proteins Nature 365, 82-85.
15. Fu, X.-D. (1995). The superfamily of arginine/serine-rich splicing factors RNA 1, 663-680
16. Fu, X.-D., and Maniatis, T. (1990) Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus Nature 343, 437-441.
17. Fu, X.-D., and Maniatis, T. (1992). The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3′ splice site. Proc. Natl. Acad. Sci USA 89, 1725-1729.
18. Fu, X.-D., Mayeda, A., Maniatis, T., and Krainer, A.R. (1992) General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5′ and 3′ splice site selection. Proc. Natl. Acad Sci USA 89, 11224-11228.
19. Ge, H., and Manley, J.L. (1990). A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell 62, 25-34.
20. Goodall, G.J., and Filipowicz, W. (1989) The AU-rich sequences present in the introns of plant nuclear pre-mRNAs are required for splicing. Cell 58, 473-483.
21. Goralski, T.J., Edstrom, J.E., and Baker, B.S. (1989) The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins. Cell 56, 1011-1018.
22. Gui, J.F., Lane, W.S., and Fu, X.D. (1994a). A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature 369, 678-682.
23. Gui, J.F., Tronchere, H., Chandler, S.D., and Fu, X.D. (1994b). Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors Proc. Natl. Acad. Sci. USA 91, 10824-10828.
24. Hartmuth, K., and Barta, A. (1986). In vitro processing of a plant pre-mRNA in a HeLa cell nuclear extract. Nucleic Acids Res. 14, 7513-7528.
25. Kim, Y.J., Zuo, P., Manley, J.L., and Baker, B.S. (1992). The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2. Genes Dev. 6, 2569-2579.
26. Kohtz, J.D., Jamison, S.F., Will, C.L., Zuo, P., Luhrmann, R., Garcia Blanco, M.A., and Manley, J.L. (1994). Protein-protein interactions and 5′-splice-site recognition in mammalian mRNA precursors. Nature 368, 119-124
27. Krainer, A.R., Conway, G.C., and Kozak, D. (1990). The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites. Cell 62, 35-42.
28. Kramer, A., and Keller, W. (1990) Preparation and fractionation of mammalian extracts active in pre-mRNA splicing. Methods Enzymol. 181, 3-19.
29. Kulesza, H., Simpson, G.G., Waugh, R., Beggs, J.D., and Brown, J.W. (1993) Detection of a plant protein analogous to the yeast spliceosomal protein, PRP8 FEBS Lett 318, 4-6.
30. Lazar, G., Schaal, T., Maniatis, T., and Goodman, H.M. (1995). Identification of a plant serine-arginine-rich protein similar to the mammalian splicing factor SF2/ASF Proc. Natl. Acad. Sci. USA 92, 7672-7676
31. Li, H., and Bingham, P.M. (1991). Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing. Cell 67, 335-342.
32. Lopato, S., Mayeda, A., Krainer, A., and Barta, A. (1996). Pre-mRNA splicing in plants: Characterization of SR splicing factors. Proc. Natl. Acad Sci. USA 93, 3074-3079.
33. Lou, H., McCullough, A.J., and Schuler, M.A. (1993). 3′ Splice site selection in dicot plant nuclei is position dependent Mol Cell Biol 13, 4485-4493
34. Luehrsen, K.R., and Walbot, V. (1994). Addition of A- and U-rich sequence increases the splicing efficiency of a deleted form of a maize intron Plant Mol Biol. 24, 449-463.
35. Luehrsen, K.R., Taha, S., and Walbot, V. (1994). Nuclear pre-mRNA processing in higher plants. Prog. Nucleic Acids Res. Mol. Biol 47, 149-193.
36. Maniatis, T. (1991) Mechanisms of alternative pre-mRNA splicing. Science 251, 33-34
37. Mayeda, A., and Krainer, A.R. (1992). Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell 6B, 365-375.
38. Mayeda, A., Zahler, A.M., Krainer, A.R., and Roth, M.B. (1992). Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proc Natl. Acad Sci USA 89, 1301-1304
39. McCullough, A.J., Lou, H., and Schuler, M.A. (1993). Factors affecting authentic 5′ splice site selection in plant nuclei Mol. Cell. Biol. 13, 1323-1331
40. Mermoud, J.E., Cohen, P., and Lamond, A.I. (1992). Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing. Nucleic Acids Res. 20, 5263-5269.
41. Mermoud, J.E., Cohen, P.T., and Lamond, A.I. (1994). Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism. EMBO J. 13, 5679-5688.
42. Pawlowski, K., Kunze, R., De Vries, S., and Bisseling, T. (1994). Isolation of total, poly(A) and polysomal RNA from plant tissues. In Plant Molecular Biology Manual, S.B. Gelvin and R.A. Schilperoort, eds (Dordrecht, The Netherlands: Kluwer Academic Publishers), pp 1-13.
43. Pearson, W.R., and Lipman, D.J. (1988). Improved tools for biological sequence comparison. Proc. Natl Acad. Sci. USA 85, 2444-2448.
44. Roscigno, R.F., and Garcia-Blanco, M.A. (1995). SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome. RNA 1, 692-706.
45. Roth, M.B., Murphy, C., and Gall, J.G. (1990). A monoclonal antibody that recognizes a phosphorylated epitope slams lampbrush chromosome loops and small granules in the amphibian germinal vesicle J. Cell Biol. 111, 2217-2223.
46. Roth, M.B., Zahler, A.M., and Stolk, J.A. (1991). A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J Cell Biol 115, 587-596.
47. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory).
48. Screaton, G.R., Caceres, J.F., Mayeda, A., Bell, M.V., Plebanski, M., Jackson, D.G., Bell, J.I., and Krainer, A.R. (1995). Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J. 14, 4336-4349.
49. Simpson, G.G., and Brown, J.W.S. (1993). Efficient splicing of an AU-rich antisense intron sequence. Plant Mol. Biol. 21, 205-211.
50. Simpson, G.G., Vaux, P., Clark, G.P., Waugh, R., Beggs, J.D., and Brown, J.W.S. (1991). Evolutionary conservation of the spliceosomal protein U2B″. Nucleic Acids Res. 19, 5213-5222.
51. Simpson, G.G., Clark, G.P., Rothnie, H.M., Boelens, W., van Venrooij, W., and Brown, J.W.S. (1995). Molecular characterization of the spliceosomal proteins U1A and U2B″ from higher plants. EMBO J. 14, 4540-4550.
52. Solymosy, F., and Pollak, T. (1993). Uridylate-rich small nuclear RNAs (UsnRNAs), their genes and pseudogenes, and UsnRNPs in plants: Structure and function A comparative approach. Crit. Rev. Plant Sci 12, 275-369.
53. Sun, Q., Mayeda, A., Hampson, R.K., Krainer, A.R., and Rottman, F.M. (1993). General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer. Genes Dev. 7, 2598-2608.
54. Tarn, W.Y., and Steitz, J.A. (1995). Modulation of 5′ splice site choice in pre-messenger RNA by two distinct steps. Proc. Natl. Acad. Sci. USA 92, 2504-2508.
55. Tazi, J., Daugeron, M.C., Cathala, G., Brunei, C., and Jeanteur, P. (1992). Adenosine phosphorothioates (ATP alpha S and ATP tau S) differentially affect the two steps of mammalian pre-mRNA splicing. J. Biol. Chem. 267, 4322-4326
56. Tazi, J., Kornstadt, U., Rossi, F., Jeanteur, P., Cathala, G., Brunei, C., and Luhrmann, R. (1993). Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing. Nature 363, 283-286.
57. Van Santen, V.L., and Spritz, R.A. (1987). Splicing of plant pre-mRNAs in animal systems and vice versa. Gene 56, 253-265
58. Waigmann, E., and Barta, A. (1992). Processing of chimeric introns in dicot plants: Evidence for a close cooperation between 5′ and 3′ splice sites. Nucleic Acids Res. 20, 75-81.
59. Wiebauer, K., Herrero, J.-J., and Filipowicz, W. (1988) Nuclear pre-mRNA processing in plants: Distinct modes of 3′-splice-site selection in plants and animals. Mol. Cell. Biol. 8, 2042-2051
60. Wu, J.Y., and Maniatis, T. (1993). Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell 75, 1061-1070.
61. Zahler, A.M., Lane, W.S., Stolk, J.A., and Roth, M.B. (1992). SR proteins: A conserved family of pre-mRNA splicing factors. Genes Dev 6, 837-847.
62. Zahler, A.M., Neugebauer, K.M., Lane, W.S., and Roth, M.B. (1993) Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 260, 219-222.