Gap junctional intercellular communication in bone

Cells and Materials

Volumn 6, Issue 1-3, 1996, Pages 1-10

  Donahue, Henry J ^a   Vander Molen, Monique A ^b   Yellowley, Clare E ^a   Li, Zhongyong ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Biophysical signal transduction; Bone; Connexin; Electric fields; Gap junctions; Intercellular communication; Mechanochemical transduction; Osteoblast; Osteocyte; Parathyroid hormone (PTH)

Indexed keywords

ALKALINE PHOSPHATASE; CONNEXIN 43; OCTANOL; PARATHYROID HORMONE;

BIOPHYSICS; BONE CELL; BONE METABOLISM; CELL COMMUNICATION; ELECTRIC FIELD; ENZYME ACTIVITY; GAP JUNCTION; HUMAN; HUMAN CELL; OSTEOBLAST; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030324762     PISSN: 10516794     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Akisaka T, Yoshida H, Kogaya Y, Kim S, Yamamoto M, Kataoka K (1990) Membrane modifications in chick osteoclasts revealed by freeze-fracture replicas. Amer J Anat 188, 381-392.
2. Bastiaanse EM, Jongsma HJ, van der Laarse A, and Takens-Kwak BR (1993) Heptanol-induced decrease in cardiac gap junctional conductance is mediated by a decrease in the fluidity of membranous cholesterol-rich domains. J Membrane Biol 136, 135-145.
3. Benayahu D, Fried A, Shamay A, Cunningham N, Blumberg S, Wientroub S (1994) Differential effects of retinoic acid and growth factors on osteoblastic markers and CD10/NEP activity in stromal-derived osteoblasts. J Cell Biochem 56, 62-73.
4. Beyer EC (1993) Gap junctions. Int Rev Cytol 137, 1-37.
5. Beyer EC, Kistler J, Paul DL, Goodenough DA (1989) Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues. J Cell Biol 108, 595-605.
6. Beyer ED, Paul DL, Goodenough DA (1987) Connexin43: a protein from rat heart homologous to a gap junction protein from liver. J Cell Biol 105, 2621-2629.
7. Boitano S, Dirksen ER, Sanderson MJ. (1992) Intercellular propagation of calcium waves mediated by inositol trisphosphate. Science 258, 292-295.
8. Chiba H, Sawada N, Oyamada M, Kojima T, Iba K, Ishii S, Mori M (1994) Hormonal regulation of connexin 43 expression and gap junctional communication in human osteoblastic cells. Cell Struct Funct 19, 173-177.
9. Chiba H, Sawada N, Oyamada M, Kojima T, Nomura S, Ishii S, Mori M (1993) Relationship between the expression of the gap junction protein and osteoblast phenotype in a human osteoblastic cell line during cell proliferation. Cell Struct Funct 18, 419-426.
10. Christ GJ, Brink PR, Zhao W, Moss J, Gondre CM, Roy C, Spray DC (1993) Gap junctions modulate tissue contractility and alpha 1 adrenergic agonist efficacy in isolated rat aorta. J Pharmacol Exp Ther 266, 1054-1065.
11. Civitelli R, Beyer EC, Warlow PM, Robertson AJ, Geist ST, Steinberg TH (1993) Connexin43 mediates direct intercellular communication in human osteoblastic cell networks. J Clin Invest 91, 1888-1896.
12. Civitelli R, Fujimori A, Bernier SM, Warlow PM, Goltzman D, Hruska KA, Avioli LV. (1992) Heterogeneous intracellular free calcium responses to parathyroid hormone correlate with morphology and receptor distribution in osteogenic sarcoma cells. Endocrinology 130, 2392-2400.
13. Cooper MS (1984) Gap junctions increase the sensitivity of tissue cells to exogenous electric fields. J Theor Biol 111, 123-130.
14. Cooper MS, Miller JP, Fraser SE (1989) Electrophoretic repatterning of charged cytoplasmic molecules within tissues coupled by gap junctions by externally applied electric fields. Dev Biol 132, 179-188.
15. Cowin SC, Weinbaum S, Zeng Y (1995) A case for bone canaliculi as the anatomical site of strain generated potentials. J Biomechanics 28, 1281-1297.
16. Donahue HJ, Fryer MJ, Eriksen EF, Heath HD (1988) Differential effects of parathyroid hormone and its analogues on cytosolic calcium ion and cAMP levels in cultured rat osteoblast-like cells. J Biol Chem 263, 13522-13527.
17. Donahue HJ, Guilak F, Van der Molen M, McLeod RJ, Rubin CT, Grande DA, Brink PR (1995) Chondrocytes isolated from mature articular cartilage retain the capacity to form functional gap junctions. J Bone Mineral Res 10, 1359-1364.
18. Donahue HJ, Li Z, Zhou Z, Simon B (1995) Pulsed electromagnetic fields affect steady state levels of Cx43 mRNA in osteoblastic cells. J Bone Mineral Res 10, S207.
19. Donahue HJ, McLeod KJ, Rubin CT, Andersen J, Grine EA, Hertzberg EL, Brink PR. (1995) Cell-to-cell communication in osteoblastic networks: cell line-dependent hormonal regulation of gap junction function. J Bone Mineral Res 10, 881-889.
20. Doty SB (1981) Morphological evidence of gap junctions between bone cells. Calcif Tissue Int 33, 509-512.
21. Duncan RL, Turner CH (1995) Mechanotransduction and the functional response of bone to mechanical strain [Review]. Calcif Tissue Int 57, 344-358.
22. Fedotov VP, Gudoshnikov VI, Baranova IN (1993) [The possible participation of gap junctions in the realization of the effects of stimulators of secretory processes in the hypophysis]. Biul Eksper Biologii i Meditsiny 116, 619-621.
23. Fukada E, Yasuda I (1957) On the piezoelectric effect of bone. J Phys Soc 2, 1158-1162.
24. Gray C, Boyde A, Jones SJ (1996) Topographically induced bone formation in vitro: implications for bone implants and bone grafts. Bone 18, 115-123.
25. Hansen M, Boitano S, Dirksen ER, Sanderson MJ (1995) A role for phospholipase C activity but not ryanodine receptors in the initiation and propagation of intercellular calcium waves. J Cell Sci 108, 2583-2590.
26. Harris SA, Enger RJ, Riggs BL, Spelsberg TC. (1995) Development and characterization of a conditionally immortalized human fetal osteoblastic cell line. J Bone Mineral Res 10, 178-186.
27. Hastings GW, Mahmud FA (1988) Electrical effects in bone. J Biomed Eng 10, 515-521.
28. Jeansonne BG, Feagin FF, McMinn RW, Shoemaker RL, Rehm WS (1979) Cell-to-cell communication of osteoblasts. J Dental Res 58, 1415-1423.
29. Jones SJ, Gray C, Sakamaki H, Arora M, Boyde A, Gourdie R, Green C (1993) The incidence and size of gap junctions between the bone cells in rat calvaria. Anatomy Embryol 187, 343-352.
30. Jongen JWJM, Willemstein-Van Hove C, Van Der Meer JM, Bos MP, Juppner H, Segre GV, Abou-Samra AB, Feyen JHM, Herrmann-Erlee MPM (1995) Down-regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by transforming growth factor-B in primary fetal rat osteoblasts. Endocrinology 136, 3260-3266.
31. Lanyon LE (1993) Osteocytes, strain detection, bone modeling and remodeling. Calcif Tissue Int 53, S102-S107.
32. Marino AA, Becker RO, Soderholm SC (1971) Origin of the piezoelectric effect in bone. Calcif Tissue Res 8, 177-180.
33. Martinez Arias A (1994) Pathways of cell communication during development: signalling and epistases. Trends in Genetics 10, 219-222.
34. Mason DJ, Hillam RA, Skerry TM (1996) Constitutive in vivo mRNA expression by osteocytes of B-actin, osteocalcin, connexin-43, IGF-I, c-fos and c-jun, but not TNF-a nor tartrate-resistant acid phosphatase. J Bone Mineral Res 11, 350-357.
35. McLeod KJ (1992) Microelectrode measurements of low frequency electric field effects in cells and tissues. [Review]. Bioelectromagnetics Suppl 1, 161-178.
36. McLeod KJ, Donahue HJ, Levin PE, Fontaine MA, Rubin CT (1993) Electric fields modulate bone cell function in a density-dependent manner. J Bone Mineral Res 8, 977-984.
37. Munari-Silem Y, Lebrethon MC, Morand I, Rousset B, Saez JM (1995) Gap junction-mediated cell-to-cell communication in bovine and human adrenal cells. A process whereby cells increase their responsiveness to physiological corticotropin concentrations. J Clin Invest 95, 1429-1439.
38. Palumbo C, Palazzini S, Marotti G (1990) Morphological study of intercellular junctions during osteocyte differentiation. Bone 11, 401-406.
39. Paul DL (1986) Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol 103, 123-134.
40. Pilla AA, Nasser PR, Kaufman JJ (1992) Cell-cell communication significantly decreases thermal noise limits for electromagnetic bioeffects. Proc 14th Ann Intern Conf IEEE Eng in Med & Biol Soc (Part 1) 7, 300.
41. Rubin CT, McLeod KJ, Lanyon LE (1989) Prevention of osteoporosis by pulsed electromagnetic fields. J Bone Joint Surgery - Amer Vol 71, 411-417.
42. Saez JC, Berthoud VM, Moreno AP, Spray DC (1993) Gap junctions. Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications. Adv Second Messenger Phosphoprotein Res 27, 163-198.
43. Sanderson MJ, Charles AC, Boitano S, Dirksen ER (1994) Mechanisms and function of intercellular calcium signaling. Mol Cell Endocrinol 98, 173-187.
44. 2+ in epithelial cells. Cell Regulation 1, 585-596.
45. Schiller PC, Mehta PP, Roos BA, Howard GA (1992) Hormonal regulation of intercellular communication: parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells. Mol Endocrinol 6, 1433-1440.
46. Schirrmacher K, Brummer F, Dusing R, Bingmann D (1993) Dye and electric coupling between osteoblast-like cells in culture. Calcif Tissue Int 53, 53-60.
47. Schirrmacher K, Schmitz I, Winterhager E, Traub O, Brummer F, Jones D, Bingmann D (1992) Characterization of gap junctions between osteoblast-like cells in culture. Calcif Tissue Int 51, 285-290.
48. Shapiro F (1988) Cortical bone repair. J Bone Joint Surgery 70A, 1067-1081.
49. 2+]i oscillations and enzyme secretion in pancreatic acini. J Biol Chem 268, 19769-19775.
50. Steinberg TH, Civitelli R, Geist ST, Robertson AJ, Hick E, Veenstra RD, Wang HZ, Warlow PM, Westphale EM, Laing JG, et al. (1994) Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells. EMBO Journal 13, 744-750.
51. Turner CH (1992) Functional determinants of bone structure: beyond Wolff's law of bone transformation [editorial]. Bone 13, 403-9.
52. Vander Molen MA, McLeod KJ, Donahue HJ, Rubin CT (1996) The influence of intercellular communication in defining osteoblast activity to biophysical stimuli. Trans Ortho Res Soc 2, 338.
53. Vander Molen MA, Rubin CT, McLeod KJ, McCauley LK, Donahue HJ. (1996) Gap junctional intercellular communication contributes to hormonal responsiveness in osteoblastic networks. J Biol Chem 271, 12165-12171.
54. Weaver JC, Astumian RD (1990) The response of living cells to very weak electric fields: the thermal noise limit [published erratum appears in Science 1990 March 2; 247(4946): 1019]. Science 247, 459-462.
55. Wolburg H, Rohlmann A (1995) Structure-function relationships in gap junctions. Int Rev Cytol 157, 315-356.
56. Xia SL, Ferrier J (1992) Propagation of a calcium pulse between osteoblastic cells. Biochem Biophys Res Commun 186, 1212-1219.
57. Yamaguchi DT, Huang JT, Ma D (1995) Regulation of gap junction intercellular communication by pH in MC3T3-E1 osteoblastic cells. J Bone Mineral Res 10, 1891-1899.
58. Yamaguchi DT, Ma D, Lee A, Huang J, Gruber HE (1994) Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1 cell line. J Bone Mineral Res 9, 791-803.
59. Yancey SB, Biswal S, Revel JP (1992) Spatial and temporal patterns of distribution of the gap junction protein connexin43 during mouse gastrulation and organogenesis. Development 114, 203-212.
60. Zhang JT, Nicholson BJ (1989) Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA. J Cell Biol 109, 3391-3401.