Surface Expression of CD28 Single Chain Fv for Costimulation by Tumor Cells

Immunological Reviews

Volumn , Issue 153, 1996, Pages 209-223

  Winberg, Gösta ^a   Grosmaire, Laura S ^b   Klussman, Kerry ^b   Hayden, Martha S ^b   Perry Fell, H ^b   Ledbetter, Jeffrey A ^b   Mittler, Robert S ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; VIRUS VECTOR; ABATACEPT; ANTIBODY CONJUGATE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN FV; LEUKOCYTE ANTIGEN;

ANTIGEN EXPRESSION; GENETIC TRANSDUCTION; HELA CELL; IMMUNOSTIMULATION; PRIORITY JOURNAL; RETROVIRUS; REVIEW; TUMOR CELL; CYTOTOXICITY; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; NEOPLASM; NUCLEOTIDE SEQUENCE;

ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, DIFFERENTIATION; BASE SEQUENCE; CYTOTOXICITY, IMMUNOLOGIC; HELA CELLS; HUMANS; IMMUNOCONJUGATES; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULINS; MOLECULAR SEQUENCE DATA; NEOPLASMS;

EID: 0030300142     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065x.1996.tb00926.x     Document Type: Article

References (19)

1. Baskar, S., Ostrand-Rosenberg, S., Nabavi, N., Nadler, L. M., Freeman, G. J. & Glimcher, L. H. (1993) Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. Proc. Natl. Acad. Sci. U. S. A. 90, 5687-90.
2. Bird, R. E., Hardman, K. D. & Joacobson, J. W. (1988) Single-chain antigen-binding proteins. Science 242, 423-6.
3. Chen, L., Ashe, S., Brady, W. A., Hellstrom, I., Hellstrom, K. E., Ledbetter, J. A., McGowan, P. & Linsley, P. S. (1992) Costimulation of antitumor immunity by the B7 counter-receptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71, 1093-102.
4. Chen, L., McGowan, P., Ashe, S., Johnston, J., Li, Y., Hellstrom, I. & Hellstrom, K. E. (1994). Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity. J. Exp. Med. 179, 523-32.
5. Duan, L., Bagasra, O., Laughlin, M. A., Oakes, J. W. & Pomerantz, R. J. (1994) Potent inhibition of human immunodeficiency virus type 1 replication by an intracelluar anti-Rev single chain antibody. Proc. Natl. Acad. Sci. U. S. A. 91, 5075-9.
6. Gilliland, L. K., Norris, N. A., Marquardt, H., Tsu, T. T., Hayden, M. S., Neubauer, M. G., Yelton, D. E., Mittler, R. S. & Ledbetter, J. A. (1996) Rapid and reliable cloning of antibody variable regions and generation of recombinant single chain antibody fragments. Tissue Antigens 47, 1-20.
7. Leach, D. R., Krummel, M. F. & Allison, J. P. (1996) Enhancement of antitumor immunity by CTT A-4 blockade. Science 271, 1734-6.
8. Linsley, P. S., Brady, W., Urnes, M., Grosmaire, L. S., Damle, N. K. & Ledbetter, J. A. (1991). CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp. Med. 174, 561-9.
9. Marasco, W. A., Haseltine, W. A. & Chen, S. Y. (1993) Design, intracellular expression, and acitivity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody. Proc. Natl. Acad. Sci. U. S. A. 90, 7889-93.
10. Marengère, L. E. M., Waterhouse, P., Duncan, G. S., Mittrücker, H.-W., Feng, G.-S. & Mak, T. W. (1996) Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 272, 1170-1172.
11. Pages, F., Ragueneau, M., Rottapel, R., Truneh, A., Nunes, J., Imbert, J. & Olive, D. (1994) Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature 369, 327-9.
12. Prasad, K. V., Cai, Y. C., Raab, M., Duckworth, B., Cantley, L., Shoelson, S. E. & Rudd, C. E. (1994) T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. U. S. A. 91, 2834-8.
13. Stein, P. H., Fraser, J. D. & Weiss, A. (1994) The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3′-kinase. Mol. Cell. Biol. 14, 3392-402.
14. Tavladoraki, P., Benvenuto, E., Trinca, S., DeMartinis, D., Cattaneo, A. & Galeffi, P. (1993) Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack. Nature 366, 469-72.
15. + T cells by B7-transfected melanoma cells. Science 259, 368-70.
16. Truitt, K. E., Hicks, C. M. & Imboden, J. B. (1994). Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells. J. Exp. Med 179, 1071-6.
17. Walunas, T. L., Lenschow, D. J., Bakker, C. Y., Linsley, P. S., Freeman, G. J., Green, J. M., Thompson, C. B. & Bluestone, J. A. (1994) CTLA-4 can function as a negative regulator of T cell activation. Immunity 1, 405-13.
18. Waterhouse, P., Penninger, J. M., Timms, E., Wakeham, A., Shahinian, A., Lee, K. P., Thompson, C. B., Griesser, H. & Mak, T. W. (1995) Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 270, 985-8.
19. Wu, T. C., Huang, A. Y., Jaffee, E. M., Levitsky, H. I. & Pardoll, D. M. (1995) A reassessment of the role of B7-1 expression in tumor rejection. J. Exp. Med. 182, 1415-21.