Spontaneous p53 mutation in murine mesothelial cells: Increased sensitivity to DNA damage induced by asbestos and ionizing radiation

Toxicology and Applied Pharmacology

Volumn 141, Issue 1, 1996, Pages 264-271

  Cistulli, Cheryl A ^b   Sorger, Thomas ^a   Marsella, Jean M ^b   Vaslet, Charles A ^b   Kane, Agnes B ^b  

^a ROGER WILLIAMS UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASBESTOS; PROTEIN P53;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL CULTURE; CELL CYCLE; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; DRUG SENSITIVITY; FLOW CYTOMETRY; GROWTH RATE; IMMUNOCYTOCHEMISTRY; IONIZING RADIATION; MESOTHELIUM CELL; MICRONUCLEUS TEST; NONHUMAN; POINT MUTATION; RADIOSENSITIVITY;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0030296979     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.0283     Document Type: Article

References (55)

1. Aust, A. E. (1994). The role of iron in asbestos-induced cancer. In Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres (J. M. G. Davis and M.-C. Jaurand, Eds.), pp. 53-61. Springer-Verlag, Berlin.
2. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1987). Preparation of genomic DNA from mammalian tissue. In Current Protocols in Molecular Biology, pp. 2.2.1. Wiley, New York.
3. Beenken, S. W., Karsentry, G., Raycroft, L., and Lozano, G. (1991). An intron binding protein is required for transformation ability of p53. Nucleic Acids Res. 19, 4747-4752.
4. Bond, J. A., Wyllie, F. S., and Wynford-Thomas, D. (1994). Escape from senescence in human diploid fibroblasts induced directly by mutant p53. Oncogene 9, 1885-1889.
5. Cora, E. C., and Kane, A. B. (1993). Alterations in a tumor suppressor gene p53 in mouse mesotheliomas induced by crocidolite asbestos. Eur. Respir. Rev. 3, 148-150.
6. Cote, R. J., Jhanwar, S. C., Novick, S., and Pellicer, A. (1991). Genetic alterations of the p53 gene are a feature of malignant mesotheliomas. Cancer Res. 51, 5410-5416.
7. Donaldson, K., Golyasnya, N., and Davis, J. M. G. (1994). Long and short amosite asbestos samples: Comparison of chromosome-damaging effects in culture with in vivo pathogenicity. In Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres (J. M. G. Davis and M.-C. Jaurand, Eds.), pp. 220-225. Springer-Verlag, Berlin.
8. Dong, H. Y., Buard, A., Reiner, A., Levy, F., Saint-Etienne, L., and Jaurand, M.-C. (1994). Role of oxygen derivatives in the cytotoxicity and DNA damage produced by asbestos on rat pleural mesothelial cells in vitro. Carcinogenesis 15, 1251-1255.
9. Dulic, V., Kaufmann, W. K., Wilson, S. J., Tisty, T. D., Lees, E., Harper, J. W., Elledge, S. J., and Reed, S. I. (1994). p53-Dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76, 1013-1023.
10. Emerit, I., Jaurand, M. C., Saint-Etienne, L., and Levy, A. (1991). Formation of a clastogenic factor by asbestos-treated rat pleural mesothelial cells. Agents Actions 34, 410-415.
11. Fornace, A. J., Lechner, J. R., Graftstrom, R. C., and Harris, C. C. (1982). DNA repair in human bronchial epithelial cells. Carcinogenesis 3, 1373-1377.
12. Gabrielson, E. W., Rosen, G. M., Drafstrom, R. C., Strauss, E., and Harris, C. C. (1986). Studies on the role of oxygen radicals in asbestos-induced cytopathology of cultured human lung mesothelial cells. Carcinogenesis 7, 1161-1164.
13. Goodglick, L. A., and Kane, A. B. (1990). Cytotoxicity of long and short crocidolite asbestos fibers in vitro and in vivo. Cancer Res. 50, 5153-5164.
14. Goodrow, T. L., Storer, R. D., Leander, K. R., Prahalada, S. R., van Zwieten, M. J., and Bradley, M. O. (1992). Murine p53 intron sequences 5-8 and their use in polymerase chain reaction/direct sequencing analysis of p53 mutations in CD-1 mouse liver and lung tumors. Mol. Carcinog. 5, 9-15.
15. Harvey, D. M., and Levine, A. J. (1991). p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5, 2375-2385.
16. Heddle, J. A., and Carrano, A. V. (1977). The DNA content of micronuclei induced in mouse bone marrow by γ-irradiation: Evidence that micronuclei arise from acentric chromosomal fragments. Mutat. Res. 44, 63-69.
17. Hei, T. K., He, Z. Y., Piao, C. Q., and Waldren, C. (1991). The mutagenicity of mineral fibers. In Mechanisms in Fibre Carcinogenesis (R. C. Brown, J. A. Hoskins, and N. F. Johnson, Eds.), pp. 319-325. Plenum, New York.
18. Hei, T. K., Piao, C. Q., He, Z. Y., Vannais, D., and Waldren, C. A. (1992). Chrysotile fiber is a strong mutagen in mammalian cells. Cancer Res. 52, 6305-6309.
19. Hesterberg, T. W., and Barrett, J. C. (1985). Induction by asbestos fibers of anaphase abnormalities: Mechanism for aneuploidy induction and possibly carcinogenesis. Carcinogenesis 6, 473-475.
20. Hoy, C. A., Scamer, L. C., and Schimke, R. T. (1989). Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): Critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA histograms. Cytometry 10, 718-725.
21. Janssen, Y. M. W., Marsh, J. P., Absher, M. P., Gabrielson, E., Borm, P. J. A., Driscoll, K., and Mossman, B. T. (1994). Oxidant stress responses in human pleural mesothelial cells exposed to asbestos. Am. J. Respir. Crit. Care Med. 149, 795-802.
22. Jaurand, M.-C. (1991). Mechanisms of fibre genotoxicity. In Mechanisms in Fibre Carcinogenesis (R. C. Brown, J. A. Hoskins, and N. F. Johnson, Eds.), pp. 287-307. Plenum, New York.
23. Johnson, N. F., and Maples, K. R. (1994). Fiber-induced hydroxyl radical formation and DNA damage. In Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres (J. M. G. Davis and M.-C. Jaurand, Eds.), pp. 23-37. Springer-Verlag, Berlin.
24. Kamp, D. W., Graceffa, P., Pryor, W. A., and Weitzman, S. A. (1992). The role of free radicals in asbestos-induced diseases. Free Radic. Biol. Med. 12, 293-315.
25. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B., and Craig, R. W. (1991). Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51, 6304-6311.
26. Kastan, M. D., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., and Fornace, A. J., Jr. (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD 45 is defective in ataxia-telangiectasia. Cell 71, 587-597.
27. Kaufmann, W. K., and Kaufman, D. G. (1993). Cell cycle control, DNA repair and initiation of carcinogenesis. FASEB J. 7, 1188-1191.
28. Ke, Y., Reddel, R. R., Gerwin, B. I., Reddel, H. K., Somers, A. N. A., McMenamin, M. G., LaVeck, M. A., Stahel, R. A., Lechner, J. F., and Harris, C. C. (1989). Establishment of a human in vitro mesothelial model system for investigating mechanisms of asbestos-induced mesothelioma. Am. J. Pathol 134, 979-991.
29. Kinnula, V. L., Aalto, K., Raivio, K. O., Walles, S., and Linnainmaa, K. (1994). Cytotoxicity of oxidants and asbestos fibers in cultured human mesothelial cells. Free Radic. Biol. Med. 16, 169-176.
30. Kinnula, V. L., Everitt, J. I., Mangum, J. B., Chang, L.-Y., and Crapo, J. D. (1992). Antioxidant defense mechanisms in cultured pleural mesothelial cells. Am. J. Respir. Cell Mol. Biol. 7, 95-103.
31. Ko, L. J., and Prives, C. (1996). p53: Puzzle and paradigm. Genes Dev. 10, 1054-1072.
32. Kodama, Y., Boreika, C. J., Maness, S. C., and Hesterberg, T. W. (1993). Cytotoxic and cytogenetic effects of asbestos on human bronchial epithelial cells in culture. Carcinogenesis 14, 691-697.
33. Kuerbitz, S. J., Plunkette, B. S., Walsh, W. V., and Kastan, M. B. (1992). Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA 89, 7491-7495.
34. Lane, D. P. (1992). p53, guardian of the genome. Nature 358, 15-16.
35. Lechner, J. F., Tokiwa, T., LaVeck, M., Benedict, W. F., Banks Schlegel, S., Yeager, H., Banerjee, A., and Harris, C. C. (1985). Asbestos-associated chromosomal changes in human mesothelial cells. Proc. Natl. Acad. Sci. USA 82, 3884-3888.
36. Libbus, B. L., Illenye, S. A., and Craighead, J. E. (1989). Induction of DNA strand breaks in cultured rat embryo cells by crocidolite asbestos as assessed by nick translation. Cancer Res. 49, 5713-5718.
37. Linnainmaa, K., Pelin-Enlund, K., Jantunen, K., Vanhala, E., Tuomi, T., Fitzgerald, J., and Yamasaki, H. (1991). Chromosomal damage and gap junctional intercellular communication in mesothelioma cell lines and cultured human primary mesothelial cells treated with MMMF, asbestos and erionite. In Mechanisms in Fibre Carcinogenesis (R. C. Brown, J. A. Hoskins, and N. F. Johnson, Eds.), pp. 327-334. Plenum, New York.
38. McClellan, R. O., Miller, F. J., Hesterberg, T. W., Warheit, D. B., Bunn, W. B., Kane, A. B., Lippmann, M., Mast, R. W., McConnell, E. E., and Reinhardt, C. F. (1992). Approaches to evaluating the toxicity and carcinogenicity of man-made fibers: Summary of a workshop held November 11-13, 1991, Durham, North Carolina. Regul. Toxicol. Pharmacol. 16, 321-364.
39. Metcalf, R. A., Welsh, J. A., Bennett, W. P., Seddon, M. B., Lehman, T. A., Pelin, K., Linnainmaa, K., Tammilehto, L., Mattson, K., Gerwin, B. I., and Harris, C. C. (1992). p53 and Kirsten-ras-mutations in human mesothelioma cell lines. Cancer Res. 52, 2610-2615.
40. Moyer, V. D., Cistulli, C. A., Vaslet, C. A., and Kane, A. B. (1994). Oxygen radicals and asbestos carcinogenesis. Environ. Health Perspect. 102, 131-136.
41. Nelson, W. G., and Kastan, M. B. (1994). DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol. 14, 1815-1823.
42. Olfosson, K., and Mark, J. (1989). Specificity of asbestos-induced chromosomal aberrations in short-term cultured human mesothelial cells. Cancer Genet. Cytogenet. 41, 33-39.
43. Ozbun, M. A., Medina, D., and Butel, J. S. (1993). p53 mutations in mouse mammary epithelial cells: Instability in culture and discordant selection of mutations in vitro versus in vivo. Cell Growth Differ. 4, 811-819.
44. Pelin, K., Husgafvel-Pursianen, K., Valkas, M., Vanhala, E., and Linnainmaa, K. (1992). Cytotoxicity and anaphase aberrations induced by mineral fibres in cultured human mesothelial cells. Toxicol. in Vitro 6, 445-450.
45. Renier, A., Levy, F., Pilliere, F., and Jaurand, M. C. (1990). Unscheduled DNA synthesis in rat pleural mesothelial cells treated with mineral fibers. Mutat. Res. 241, 361-367.
46. Rittling, S. R., and Denhardt, D. T. (1992). p53 mutations in spontaneously immortalized 3T12 but not 3T3 mouse embryo cells. Oncogene 7, 935-942.
47. Salassidis, K., Huber, R., Zitzelsberger, H., and Bauchinger, M. (1992). Centromere detection in vinblastine- and radiation-induced micronuclei of cytokinesis-blocked mouse cells by using in situ hybridization with a mouse gamma (major) satellite DNA probe. Environ. Mol. Mutagen. 19, 1-6.
48. Smith, M. L., Chen, I.-T., Zhan, Q., Bae, I., Chen, C.-Y., Gilmer, T. M., Kastan, M. B., O'Connor, P. M., and Fornance, A. J., Jr. (1994). Interaction of the p53-regulated protein gadd 45 with proliferating cell nuclear antigen. Science 266, 1376-1380.
49. Somers, A. N. A., Mason, E. A., Gerwin, B. I., Harris, C. C., and Lechner, J. F. (1991). Effects of amosite asbestos fibers on the filaments present in the cytoskeleton of primary human mesothelial cells. In Mechanisms in Fibre Carcinogenesis (R. C. Brown, J. A. Haskins, and N. F. Johnson, Eds.), pp. 481-490. Plenum, New York.
50. Waga, S., Hannon, G. J., Beach, O., and Stillman, B. (1994). The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369, 574-578.
51. Wazer, D. E., Chu, Q., Liu, X.-L., Gao, Q., Safaii, H., and Band, V. (1994). Loss of p53 protein during radiation transformation of primary human mammary epithelial cells. Mol. Cell. Biol. 14, 2468-2478.
52. Weier, H.-U., Zitzelsberger, H. F., and Gray, J. W. (1991). Non-isotopical labeling of murine heterochromatin by in situ hybridization with in vitro-synthesized biotinylated gamma (major) satellite DNA. BioTechniques 10, 498-502.
53. Yegles, M., Saint-Etienne, L., Renier, A., Janson, X., and Jaurand, M.-C. (1993). Induction of metaphase and anaphase/telophase abnormalities by asbestos fibers in rat pleural mesothelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 9, 186-191.
54. Yin, Y., Tainsky, M. A., Bischoff, F. Z., Strong, L. C., and Wahl, G. M. (1992). Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70, 937-948.
55. Zhan, Q., Carrier, F., and Fornace, A. J., Jr. (1993). Induction of cellular p53 activity by DNA damaging agents and growth arrest. Mol. Cell. Biol. 13, 4242-4250.