-
1
-
-
0025343704
-
Bioreductive drugs and the selective induction of tumour hypoxia
-
BREMMER JCM, STRATFORD IJ, BOWLER, J. AND ADAMS G. (1990). Bioreductive drugs and the selective induction of tumour hypoxia. Br. J. Cancer, 61, 717-721.
-
(1990)
Br. J. Cancer
, vol.61
, pp. 717-721
-
-
Bremmer, J.C.M.1
Stratford, I.J.2
Bowler, J.3
Adams, G.4
-
2
-
-
0027288316
-
SR-4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours
-
BROWN JM. (1993). SR-4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours. Br. J. Cancer, 67, 1163-1170.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 1163-1170
-
-
Brown, J.M.1
-
3
-
-
0025972731
-
Tumor hypoxia can be exploited to preferentially sensitize tumours to fractionated irradiation
-
BROWN JM AND LEMMON MJ. (1991). Tumor hypoxia can be exploited to preferentially sensitize tumours to fractionated irradiation. Int. J. Radiat. Oncol. Biol. Phys., 20, 457-461.
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 457-461
-
-
Brown, J.M.1
Lemmon, M.J.2
-
4
-
-
0023910405
-
Hypoxia in tumours: A paradigm for the approach to biochemical and physiological heterogeneity
-
COLEMAN CN. (1988). Hypoxia in tumours: a paradigm for the approach to biochemical and physiological heterogeneity. J. Natl Cancer Inst., 80, 310-316.
-
(1988)
J. Natl Cancer Inst.
, vol.80
, pp. 310-316
-
-
Coleman, C.N.1
-
5
-
-
0024532975
-
In vitro hepatotoxicity of SR-4233 (3-amino-1,2,4-benzotriazine-1,4-dioxide) a hypoxic cytotoxin and potential antitumour agent
-
COSTA AK, BAKER MA, BROWN JM AND TRUDELL JR. (1989). In vitro hepatotoxicity of SR-4233 (3-amino-1,2,4-benzotriazine-1,4-dioxide) a hypoxic cytotoxin and potential antitumour agent. Cancer Res., 49, 925-929.
-
(1989)
Cancer Res.
, vol.49
, pp. 925-929
-
-
Costa, A.K.1
Baker, M.A.2
Brown, J.M.3
Trudell, J.R.4
-
6
-
-
0028200683
-
Muscle cramping in phase I clinical trials of tirapazamine (SR-4233) with and without irradiation
-
DOHERTY N, HANCOCK SL, KAYE S, COLEMAN CN, SHULMAN L, MARQUEZ C, MARISCAL C, RAMPLING R, SENAN S AND ROEMELING RV. (1994). Muscle cramping in phase I clinical trials of tirapazamine (SR-4233) with and without irradiation. Int. J. Radiat. Oncol. Biol. Phys., 29, 379-382.
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 379-382
-
-
Doherty, N.1
Hancock, S.L.2
Kaye, S.3
Coleman, C.N.4
Shulman, L.5
Marquez, C.6
Mariscal, C.7
Rampling, R.8
Senan, S.9
Roemeling, R.V.10
-
7
-
-
84965808588
-
Tumor-specific, schedule-dependent interaction between tirapazamine (SR-4233) and cisplatin
-
DORIE MJ AND BROWN JM. (1993). Tumor-specific, schedule-dependent interaction between tirapazamine (SR-4233) and cisplatin. Cancer Res., 53, 4633-4636.
-
(1993)
Cancer Res.
, vol.53
, pp. 4633-4636
-
-
Dorie, M.J.1
Brown, J.M.2
-
8
-
-
0023932431
-
Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy
-
GATENBY RA, KESSLER HB, ROSENBLUM JS, COIA LR, MODOF SKY PJ, HARTZ WH AND BRODER GJ. (1988). Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int. J. Radiat. Oncol. Biol. Phys., 10, 831-838.
-
(1988)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.10
, pp. 831-838
-
-
Gatenby, R.A.1
Kessler, H.B.2
Rosenblum, J.S.3
Coia, L.R.4
Modofsky, P.J.5
Hartz, W.H.6
Broder, G.J.7
-
9
-
-
0024395711
-
Comparison of the radiobiological properties of human tumour xenografts and rodent tumours
-
GUICHARD M. (1989). Comparison of the radiobiological properties of human tumour xenografts and rodent tumours. Int. J. Radiat. Biol., 56, 583-586.
-
(1989)
Int. J. Radiat. Biol.
, vol.56
, pp. 583-586
-
-
Guichard, M.1
-
11
-
-
0020525454
-
Radiosensitivity of four human tumor xenografts. Influence of hypoxia and cell-cell contact
-
GUICHARD M, DERTINGER H AND MALAISE EP. (1983). Radiosensitivity of four human tumor xenografts. Influence of hypoxia and cell-cell contact. Radiat. Res., 95, 602-609.
-
(1983)
Radiat. Res.
, vol.95
, pp. 602-609
-
-
Guichard, M.1
Dertinger, H.2
Malaise, E.P.3
-
12
-
-
0027730121
-
Tumor oxygenation: A new predictive parameter in locally advanced cancer of the uterine cervix
-
HÖCKEL M, VORNDRAN B, SCHLENGER K, BAUSSMANN E AND KNAPSTEIN PG. (1993). Tumor oxygenation: a new predictive parameter in locally advanced cancer of the uterine cervix. Gynecol. Oncol., 51, 141-149.
-
(1993)
Gynecol. Oncol.
, vol.51
, pp. 141-149
-
-
Höckel, M.1
Vorndran, B.2
Schlenger, K.3
Baussmann, E.4
Knapstein, P.G.5
-
13
-
-
0026513038
-
Enhancement of alkylating agents activity by SR-4233 on the FSaIIC murine fibrosarcoma
-
HOLDEN SA, TEICHER BA, ARA G, HERMAN TS AND COLEMAN CN. (1992). Enhancement of alkylating agents activity by SR-4233 on the FSaIIC murine fibrosarcoma. J. Natl. Cancer Inst., 84, 187-193.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 187-193
-
-
Holden, S.A.1
Teicher, B.A.2
Ara, G.3
Herman, T.S.4
Coleman, C.N.5
-
14
-
-
0027227590
-
Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin
-
KOCH CJ. (1993). Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin. Cancer Res., 53, 3992-3997.
-
(1993)
Cancer Res.
, vol.53
, pp. 3992-3997
-
-
Koch, C.J.1
-
15
-
-
0027477360
-
Oxygenation of head and neck tumors
-
LARTIGAU E, LE RIDANT AM, LAMBIN P, WEEGER P, MARTIN L, SIGAL R, LUSINCHI A, LUBOINSKI B, ESCHWEGE F AND GUICHARD M. (1993). Oxygenation of head and neck tumors. Cancer, 71, 2319-2325.
-
(1993)
Cancer
, vol.71
, pp. 2319-2325
-
-
Lartigau, E.1
Le Ridant, A.M.2
Lambin, P.3
Weeger, P.4
Martin, L.5
Sigal, R.6
Lusinchi, A.7
Luboinski, B.8
Eschwege, F.9
Guichard, M.10
-
16
-
-
84982728136
-
Oxygen tension measurements in human tumors: The Institut Gustave-Roussy experience
-
LARTIGAU E, RANDRIANARIVELO H, MARTIN L, STERN S, THOMAS CD, GUICHARD M, WEEGER P, LE RIDANT A-M, LUBOINSKI B, NGUYEN T, ORTOLI J-C, GRANGE F, AVRIL M-F, LUSINCHI A, WIBAULT P, HAIE-MEDER C, GERBAULET A AND ESCHWEGE F. (1994). Oxygen tension measurements in human tumors: the Institut Gustave-Roussy experience. Radiat. Oncol. Invest., 1, 285-291.
-
(1994)
Radiat. Oncol. Invest.
, vol.1
, pp. 285-291
-
-
Lartigau, E.1
Randrianarivelo, H.2
Martin, L.3
Stern, S.4
Thomas, C.D.5
Guichard, M.6
Weeger, P.7
Le Ridant, A.-M.8
Luboinski, B.9
Nguyen, T.10
Ortoli, J.-C.11
Grange, F.12
Avril, M.-F.13
Lusinchi, A.14
Wibault, P.15
Haie-Meder, C.16
Gerbaulet, A.17
Eschwege, F.18
-
17
-
-
0028928551
-
Does tirapazamine (SR-4233) have any effect on the surviving fraction of 3 human cell lines at clinically relevant partial oxygen pressure?
-
LARTIGAU E AND GUICHARD M. (1995). Does tirapazamine (SR-4233) have any effect on the surviving fraction of 3 human cell lines at clinically relevant partial oxygen pressure? Int. J. Radiat. Biol., 21, 211-216.
-
(1995)
Int. J. Radiat. Biol.
, vol.21
, pp. 211-216
-
-
Lartigau, E.1
Guichard, M.2
-
18
-
-
0026572272
-
Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive anti-tumour agents: Pharmacology and activity in vitro and in vivo
-
MINCHINTON AL, LEMMON MJ, TRACY M, POLLART DJ, MARTINEZ AP AND BROWN JM. (1992). Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive anti-tumour agents: pharmacology and activity in vitro and in vivo. Int. J. Radiat. Oncol. Biol. Phys., 22, 701-705.
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.22
, pp. 701-705
-
-
Minchinton, A.L.1
Lemmon, M.J.2
Tracy, M.3
Pollart, D.J.4
Martinez, A.P.5
Brown, J.M.6
-
19
-
-
0002786083
-
Importance of tumour hypoxia in radiotherapy. A meta-analysis of controlled clinical trials
-
OVERGAARD J. (1991). Importance of tumour hypoxia in radiotherapy. A meta-analysis of controlled clinical trials. Radiother. Oncol., 24, S64.
-
(1991)
Radiother. Oncol.
, vol.24
-
-
Overgaard, J.1
-
20
-
-
0026698228
-
Use of hypoxia-directed drugs in the therapy of solid tumors
-
ROCKWELL S. (1992). Use of hypoxia-directed drugs in the therapy of solid tumors. Semin. Oncol., 19, 29-40.
-
(1992)
Semin. Oncol.
, vol.19
, pp. 29-40
-
-
Rockwell, S.1
-
21
-
-
0025328583
-
Hypoxic fractions of human tumors xenografted into mice: A review
-
ROCKWELL S AND MOULDER JE. (1990). Hypoxic fractions of human tumors xenografted into mice: a review. Int. J. Radiat. Oncol. Biol. Phys., 19, 197-202.
-
(1990)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.19
, pp. 197-202
-
-
Rockwell, S.1
Moulder, J.E.2
-
22
-
-
0026003123
-
Hypoxia-induced drug resistance: Comparison to P-glycoprotein-associated drug resistance
-
SAKATA K, TAK KWOK T, MURPHY BJ, LADEROUTE KR, GORDON GR AND SUTHERLAND RM. (1991). Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance. Br. J. Cancer, 64, 809-814.
-
(1991)
Br. J. Cancer
, vol.64
, pp. 809-814
-
-
Sakata, K.1
Tak Kwok, T.2
Murphy, B.J.3
Laderoute, K.R.4
Gordon, G.R.5
Sutherland, R.M.6
-
23
-
-
0026663207
-
Biochemical pharmacology of chemotherapeutic drugs used as radiations enhancers
-
SCHILSKY RL. (1992). Biochemical pharmacology of chemotherapeutic drugs used as radiations enhancers. Semin. Oncol., 19, 2-7.
-
(1992)
Semin. Oncol.
, vol.19
, pp. 2-7
-
-
Schilsky, R.L.1
-
24
-
-
0027396881
-
Toxicology of daily administration to mice of the radiation potentiator SR 4233
-
SPIEGEL JF, SPEAR MA AND BROWN JM. (1993). Toxicology of daily administration to mice of the radiation potentiator SR 4233. Radiother. Oncol., 26, 79-81.
-
(1993)
Radiother. Oncol.
, vol.26
, pp. 79-81
-
-
Spiegel, J.F.1
Spear, M.A.2
Brown, J.M.3
-
25
-
-
8944221917
-
The therapeutic response of a variety of human tumour xenografts
-
Winograd B, Peckham MJ and Pinedo HM (eds) Springer: London
-
STEEL GG AND PECKHAM MJ. (1992). The therapeutic response of a variety of human tumour xenografts. In Human Tumour Xenografts in Anticancer Drug Development, Winograd B, Peckham MJ and Pinedo HM (eds) pp. 4-9, Springer: London.
-
(1992)
Human Tumour Xenografts in Anticancer Drug Development
, pp. 4-9
-
-
Steel, G.G.1
Peckham, M.J.2
-
26
-
-
0019349297
-
Classification of antineoplastic agents by their selective toxicities towards oxygenated and hypoxic tumour cells
-
TEICHER BA, LAZO JS AND SARTORELLI AC. (1981). Classification of antineoplastic agents by their selective toxicities towards oxygenated and hypoxic tumour cells. Cancer Res., 41, 73-81.
-
(1981)
Cancer Res.
, vol.41
, pp. 73-81
-
-
Teicher, B.A.1
Lazo, J.S.2
Sartorelli, A.C.3
-
27
-
-
0023736971
-
Guidelines for the Welfare of Animals in Experimental Neoplasia
-
UCKCCCR. (1988). Guidelines for the Welfare of Animals in Experimental Neoplasia. Br. J. Cancer, 58, 109-113.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 109-113
-
-
-
28
-
-
0025329088
-
Oxygenation of human tumors
-
VAUPEL PW. (1990). Oxygenation of human tumors. Stralenther. Onkol., 166, 377-386.
-
(1990)
Stralenther. Onkol.
, vol.166
, pp. 377-386
-
-
Vaupel, P.W.1
-
29
-
-
0024322497
-
Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer
-
WEISSBERG JB, SON YH, PAPAC RJ, SASAKI C, FISCHER DB AND LAWRENCE R. (1989). Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys., 17, 3-9.
-
(1989)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.17
, pp. 3-9
-
-
Weissberg, J.B.1
Son, Y.H.2
Papac, R.J.3
Sasaki, C.4
Fischer, D.B.5
Lawrence, R.6
-
30
-
-
0027328452
-
The experimental development of bioreductive drugs and their role in cancer therapy
-
WORKMAN P AND STRATFORD IJ. (1993). The experimental development of bioreductive drugs and their role in cancer therapy. Cancer Met. Rev., 12, 73-82.
-
(1993)
Cancer Met. Rev.
, vol.12
, pp. 73-82
-
-
Workman, P.1
Stratford, I.J.2
-
31
-
-
0022493495
-
SR-4233: A new bioreductive agent with high selective toxicity for hypoxic mammalian cells
-
ZEMAN EM, BROWN JM, LEMMON MJ, HIRST VK AND LEE WW. (1986). SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells. Int. J. Radiat. Oncol. Biol. Phys., 12, 1239-1242.
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1239-1242
-
-
Zeman, E.M.1
Brown, J.M.2
Lemmon, M.J.3
Hirst, V.K.4
Lee, W.W.5
-
32
-
-
0023750547
-
Enhancement of radiation-induced tumour cell killing by the hypoxic cell toxin SR-4233
-
ZEMAN EM, HIRST VK, LEMMON MJ AND BROWN JM (1988). Enhancement of radiation-induced tumour cell killing by the hypoxic cell toxin SR-4233. Radiother. Oncol., 12, 209-218.
-
(1988)
Radiother. Oncol.
, vol.12
, pp. 209-218
-
-
Zeman, E.M.1
Hirst, V.K.2
Lemmon, M.J.3
Brown, J.M.4
|