Symposium 2. Defects in substrate oxidation involved in the predisposition to obesity

Proceedings of the Nutrition Society

Volumn 55, Issue 3, 1996, Pages 817-828

  Astrup, Arne ^a   Buemann, Benjamin ^a   Toubro, Søren ^a   Raben, Anne ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

CALORIC INTAKE; FAT INTAKE; FEEDING BEHAVIOR; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; OBESITY; OXIDATION REDUCTION REACTION; PHYSIOLOGY; REVIEW; SKELETAL MUSCLE;

DIETARY FATS; ENERGY INTAKE; FOOD HABITS; GENE EXPRESSION; GLUCOSE; HUMANS; MUSCLE, SKELETAL; OBESITY; OXIDATION-REDUCTION;

EID: 0030279037     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/pns19960081     Document Type: Conference Paper

References (46)

1. Astrup, A., Buemann, B., Christensen, N. J. & Madsen, J. (1992). 24-h energy expenditure and sympathetic activity in postobese women consuming a high-carbohydrate diet. American Journal of Physiology 262, E282-E288.
2. Astrup, A., Buemann, B., Christensen, N. J. & Toubro, S. (1994a). Failure to increase lipid oxidation in response to increasing dietary fat content in formerly obese women. American Journal of Physiology 266, E592-E599.
3. Astrup, A., Buemann, B., Toubro, S., Ranneries, C. & Raben, A. (1996). Low resting metabolic rate in subjects predisposed to obesity: a role for thyroid status. American Journal of Clinical Nutrition 63, 879-883.
4. Astrup, A., Buemann, B., Western, P., Toubro, S., Raben, A. & Christensen, N. J. (1994b). Obesity as an adaptation to a high-fat diet: evidence from a cross-sectional study. American Journal of Clinical Nutrition 59, 350-355.
5. Astrup, A. & Flatt, J. P. (1996). Metabolic determinants of body weight regulation. In Regulation of Body Weight. Biological and Behavioral Mechanisms, pp. 193-210 [C. Bouchard and G. A. Bray, editors]. Chichester: John Wiley & Sons Ltd.
6. Astrup, A. & Raben, A. (1996a). Glucostatic control of intake and obesity. Proceedings of the Nutrition Society 55, 417-127.
7. Astrup, A. & Raben, A. (1996a). Mono- and disaccharides: Nutritional aspects. In Carbohydrates in Food, pp. 159-189 [A.-C. Eliasson, editor]. New York: Marcel Dekker Inc.
8. Astrup, A., Sørensen, C., B̈low, J., Buemann, B., Madsen, J. & Christensen, N. J. (1994c). Fat mobilization and utilization during rest and exercise in postobese women. International Journal of Obesity 18, Suppl. 2, 23 Abstr.
9. Bouchard, C. & Bray, G. A. (1996). Introduction. In Regulation of Body Weight. Biological and Behavioral Mechanisms, pp. 1-13 [C. Bouchard and G. A. Bray, editors]. Chichester: John Wiley & Sons Ltd.
10. Bouchard, C., Dériaz, O., Pérusse, L. & Tremblay, A. (1994). Genetics of energy expenditure in humans. In The Genetics of Obesity, pp. 135-145 [C. Bouchard, editor]. London and Tokyo: CRC Press.
11. Bouchard, C., Tremblay, A., Després, J. P., Nadeau, A., Lupien, P. J., Thériault, G., Dussault, J., Moorjani, S., Pinault, S. & Fournier, G. (1990). The response to long-term overfeeding in identical twins. New England Journal of Medicine 322, 1477-1482.
12. Bouchard, C., Tremblay, A., Nadeau, A., Després, J. P., Thériault, G., Boulay, M. R., Lortie, G., Leblanc, C. & Founier, G. (1989). Genetic effect in resting and exercise metabolic rates. Metabolism 38, 364-370.
13. Buemann, B., Toubro, S., Raben, A. & Astrup, A. (1994). Substrate oxidations in postobese women on 72-h high fat diet. A possible abnormal postprandial response? International Journal of Obesity 18, Suppl. 2, 97 Abstr.
14. Considine, R. V., Sinha, M. K., Heiman, M. L., Kriaucinas, A., Stephens, T. W., Nyce, M. R., Channesian, J. P., Marco, C. C., McKee, L. J., Bauer, T. L. & Caro, J. F. (1996). Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New England Journal of Medicine 334, 292-295.
15. Dériaz, O., Dionne, F., Pérusse, L., Tremblay, A., Vohol, M. C., Côte, G. & Bouchard, C. (1994). DNA variation in the genes of the Na,K-adenosine triphosphatase and its relation with resting metabolic rate, respiratory quotient, and body fat. Journal of Clinical Investigation 93, 838-843.
16. Drewnowski, A., Brunzell, J. D., Sande, K., Iverius, P. H. & Greenwood, M. R. C. (1985). Sweet tooth reconsidered: taste responsiveness in human obesity. Physiology and Behavior 35, 617-622.
17. Drewnowski, A., Kurth, C. L. & Rahaim, J. E. (1991). Taste preferences in human obesity: environmental and familial factors. American Journal of Clinical Nutrition 54, 635-641.
18. Dyck, D. J., Putman, C. T., Heighenhauser, G. J. F., Hultman, E. & Spriet, L. L. (1993). Regulation of fat-carbohydrate interaction in skeletal muscle during intense aerobic cycling. American Journal of Physiology 265, E852-E859.
19. Eckel, R. H., Ailhaud, G., Astrup, A., Flatt, J. P., Hauner, H., Levine, A. S., Prentice, A. M., Ricquier, D., Steffens, A. B. & Woods, S. C. (1996). Group report. What are the metabolic and physiological mechanisms associated with the regulation of body weight? In Regulation of Body Weight: Biological and Behavioral Mechanisms, pp. 222-238 [C. Bouchard and G. A. Bray, editors]. Chichester: John Wiley & Sons Ltd.
20. Ferraro, R. T., Eckel, R. H., Larson, D. E., Fontvieille, A. M., Rising, R., Jensen, D. R. & Ravussin, E. (1993). Relationship between skeletal muscle lipoprotein lipase activity and 24-hour macronutrient oxidation. Journal of Clinical Investigation 92, 441-445.
21. Flatt, J. P. (1987). Dietary fat, carbohydrate balance, and weight maintenance: effects of exercise. American Journal of Clinical Nutrition 45, 296-306.
22. Hansen, H., Raben, A. & Astrup, A. (1995). The habitual diet of post-obese is lower in fat and higher in carbohydrate compared to matched controls. International Journal of Obesity 19, 82 Abstr.
23. Heitmann, B. L., Lissner, L., Sørensen, T. I. A. & Bengtsson, C. (1995). Dietary fat intake and weight gain in women genetically predisposed for obesity. American Journal of Clinical Nutrition 61, 1213-1217.
24. Klausen, B., Toubro, S. & Astrup, A. (1996). High-intensity exercise stimulates the subsequent day's fat intake. International Journal of Obesity 20, Suppl. 4, 67 Abstr.
25. Lean, M. E. J. & James, W. P. T. (1988). Metabolic effects of isoenergetic nutrient exchange over 24 hours in relation to obesity in women. International Journal of Obesity 12, 15-27.
26. Lillioja, S., Young, A. A., Culter, C. L., Ivy, J. L., Abbott, W. G., Zawadski, J. K., Yki-Jarvinen, H., Christin, L., Secomb, T. W. & Bogardus, C. (1987). Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. Journal of Clinical Investigation 80, 415-424.
27. Prentice, A. M. (1995). Alcohol and obesity. International Journal of Obesity 19, Suppl., 544-550.
28. Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, J. J. & Astrup, A. (1994). Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity. American Journal of Physiology 267, E549-E559.
29. Raben, A., Toubro, S. & Astrup, A. (1996). Improved insulin sensitivity after 14-d ad libitum sucrose-rich diet compared with a fat-rich or starch-rich diet. International Journal of Obesity 20, Suppl. 4, 67 Abstr.
30. Randle, P. J., Garland, P. B., Hales, C. N. & Newsholme, E. A. (1963). The glucose fatty acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1, 785-789.
31. Ravussin, E. (1995). Metabolic differences and the development of obesity. Metabolism 9, Suppl. 3, 12-14.
32. Rolls, B. J., Kim-Harris, S., Fischman, M. W., Foltin, R. W., Moran, T. H. & Stoner, S. A. (1994). Satiety after preloads with different amounts of fat and carbohydrate: implications for obesity. American Journal of Clinical Nutrition 60, 476-487.
33. Seidell, J. C., Muller, D. C., Sorkin, J. D. & Andres, R. (1992). Fasting respiratory exchange ratio and resting metabolic rate as predictors of weight gain: the Baltimore Longitudinal Study on Aging. International Journal of Obesity 16, 667-674.
34. Simoneau, J.-A. & Bouchard, C. (1995). Skeletal muscle metabolism and body fat content in men and women. Obesity Research 3, 23-29.
35. Simoneau, J.-A., Tremblay, A., Thériault, G. & Bouchard, C. (1994). Relationships between the metabolic profile of skeletal muscle and body fat gain in response to overfeeding. Medicine and Science in Sports and Exercise 5, S159.
36. Spraul, M., Ravussin, E., Fontvieille, A. M., Rising, R., Larson, D. E. & Anderson, E. A. (1993). Reduced sympathetic nervous activity. A potential mechanism predisposing to body weight gain. Journal of Clinical Investigation 92, 1730-1735.
37. Swinburn, B., Nyomba, B. L., Saad, M. F., Zurlo, F. & Raz, I. (1991). Insulin resistance associated with lower rates of weight gain in Pima Indians. Journal of Clinical Investigation 88, 168-173.
38. Toubro, S., Christensen, N. J. & Astrup, A. (1995). Reproducibility of 24-h energy expenditure, substrate utilization and spontaneous physical activity in obesity measured in a respiration chamber. International Journal of Obesity 19, 544-549.
39. Toubro, S., Sørensen, T. I. A., Rønn, B., Christensen, N. J. & Astrup, A. (1996). 24-h energy expenditure: the role of body composition, thyroid status, sympathetic activity and family membership. Journal of Endocrinology and Metabolism (In the Press).
40. Toubro, S., Western, P., Bülow, J., Macdonald, I., Raben, A., Christensen, N. J., Madsen, J. & Astrup, A. (1994). Insulin sensitivity in post-obese women. Clinical Science 84, 407-413.
41. Tremblay, A. (1995). Differences in fat balance underlying obesity. International Journal of Obesity 19, S10-S14.
42. Verboeket-van de Venne, W. P. H. G., Westerterp, K. R. & ten Hoor, F. (1994). Substrate utilization in man: effects of dietary fat and carbohydrate. Metabolism 43, 152-156.
43. Wade, A. J., Marbut, M. M. & Round, J. M. (1990). Muscle fibre type and aetiology of obesity. Lancet 335, 805-808.
44. Weigle, D. S., Bukowski, T. R., Foster, D. C., Holderman, S., Kramer, J. M., Lasser, G., Lofton-Day, C. E., Prunkard, D. E., Raymond, C. & Kuijper, J. L. (1995). Recombinant ob protein reduces feeding and body weight in ob/ob mouse. Journal of Clinical Investigation 96, 2065-2070.
45. Zurlo, F., Lillioja, S., Esposito-Del Puente, A., Nyomba, B. L., Raz, I., Saad, M. F., Swinburn, B. A., Knowler, W. C., Bogardus, C. & Ravussin, E. (1990). Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. American Journal of Physiology 259, E650-E657.
46. Zurlo, F., Nemeth, P. M., Choksi, R. M., Sesodia, S. & Ravussin, E. (1994). Whole-body energy metabolism and skeletal muscle biochemical characteristics. Metabolism 43, 481-486.