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Volumn 30, Issue 6, 1996, Pages 560-570

The cytokine network in rheumatoid arthritis: Definition of TNFα as a therapeutic target

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030276893     PISSN: 00358819     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (86)
  • 1
    • 0021034058 scopus 로고
    • Hypothesis: Role of aberrant HLA-DR expression and antigen presentation in the induction of endocrine autoimmunity
    • Bottazzo GF, Pujol-Borrell R, Hanafusa T, Feldmann M. Hypothesis: role of aberrant HLA-DR expression and antigen presentation in the induction of endocrine autoimmunity. Lancet 1983;ii:1115-9.
    • (1983) Lancet , vol.2 , pp. 1115-1119
    • Bottazzo, G.F.1    Pujol-Borrell, R.2    Hanafusa, T.3    Feldmann, M.4
  • 2
    • 0027328370 scopus 로고
    • Autoimmune disease
    • Steinman L. Autoimmune disease. Sci Am 1993;269:107-14.
    • (1993) Sci Am , vol.269 , pp. 107-114
    • Steinman, L.1
  • 3
    • 0029954214 scopus 로고    scopus 로고
    • Insulin dependent diabetes mellitus
    • Tisch R, McDevitt H. Insulin dependent diabetes mellitus. Cell 1996;85:291-7.
    • (1996) Cell , vol.85 , pp. 291-297
    • Tisch, R.1    McDevitt, H.2
  • 4
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A co-ordinated immunological attack against myelin in the central nervous system
    • Steinman L. Multiple sclerosis: a co-ordinated immunological attack against myelin in the central nervous system. Cell 1996;85:299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 5
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • Goodnow CC. Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci USA 1996;93: 2264-71.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 6
    • 0029006389 scopus 로고
    • How can cryptic epitopes trigger autoimmunity?
    • Lanzavecchia A. How can cryptic epitopes trigger autoimmunity? J Exp Med 1995;181:1945-8.
    • (1995) J Exp Med , vol.181 , pp. 1945-1948
    • Lanzavecchia, A.1
  • 9
    • 0024314554 scopus 로고
    • Inhibitory effect of TXFα antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan FM, Chantry D, Jackson A, Maini R, Feldmann M. Inhibitory effect of TXFα antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 1989;ii: 244-7.
    • (1989) Lancet , vol.2 , pp. 244-247
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.3    Maini, R.4    Feldmann, M.5
  • 10
    • 0025099962 scopus 로고
    • Cytokine production in the rheumatoid joint: Implications for treatment
    • Feldmann M, Brennan FM, Chantry D, Haworth C, et al. Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis 1990;49:480-6.
    • (1990) Ann Rheum Dis , vol.49 , pp. 480-486
    • Feldmann, M.1    Brennan, F.M.2    Chantry, D.3    Haworth, C.4
  • 11
    • 0024538157 scopus 로고
    • Factors predicting a poor life prognosis in rheumatoid arthritis: An eight year prospective study
    • Erhardt CC, Mumford PA, Venables PJW, Maini RN. Factors predicting a poor life prognosis in rheumatoid arthritis: an eight year prospective study. Ann Rheum Dis 1989;48:7-13.
    • (1989) Ann Rheum Dis , vol.48 , pp. 7-13
    • Erhardt, C.C.1    Mumford, P.A.2    Venables, P.J.W.3    Maini, R.N.4
  • 12
    • 0027474185 scopus 로고
    • What is the natural history of rheumatoid arthritis?
    • Pincus T, Callahan LF. What is the natural history of rheumatoid arthritis? Rheum Dis Clin North Am 1993;19:123-51.
    • (1993) Rheum Dis Clin North Am , vol.19 , pp. 123-151
    • Pincus, T.1    Callahan, L.F.2
  • 13
    • 0027375302 scopus 로고
    • Twin concordance rates for rheumatoid arthritis: Results from a nationwide study
    • Silman AJ, MacGregor AJ, Thomson W, Holligan S, et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 1993;32:903-7.
    • (1993) Br J Rheumatol , vol.32 , pp. 903-907
    • Silman, A.J.1    MacGregor, A.J.2    Thomson, W.3    Holligan, S.4
  • 14
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987;30:1205-13.
    • (1987) Arthritis Rheum , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 15
    • 0023912807 scopus 로고
    • A molecular basis for the MHC class II-associated autoimmunity
    • Todd JA, Acha-Orbea H, Bell JI, Chao N, et al. A molecular basis for the MHC class II-associated autoimmunity. Science 1988;240:1003-9.
    • (1988) Science , vol.240 , pp. 1003-1009
    • Todd, J.A.1    Acha-Orbea, H.2    Bell, J.I.3    Chao, N.4
  • 16
    • 0028952168 scopus 로고
    • Peptide binding specificity of HLA-DR4 molecules: Correlation with rheumatoid arthritis association
    • Hammer J, Gallazzi F, Bono F, Karr RW, et al. Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association. J Exp Med 1995;181:1847-55.
    • (1995) J Exp Med , vol.181 , pp. 1847-1855
    • Hammer, J.1    Gallazzi, F.2    Bono, F.3    Karr, R.W.4
  • 17
    • 0028001431 scopus 로고
    • Incidence of rheumatoid arthritis: Do the observed age-sex interaction patterns support a role of androgenic-anabolic steroid deficiency in its pathogenesis?
    • Masi AT. Incidence of rheumatoid arthritis: do the observed age-sex interaction patterns support a role of androgenic-anabolic steroid deficiency in its pathogenesis? Br J Rheumatol 1994;33:697.
    • (1994) Br J Rheumatol , vol.33 , pp. 697
    • Masi, A.T.1
  • 18
    • 0028330068 scopus 로고
    • Rheumatoid arthritis: Another New World disease?
    • Buchanan WW. Rheumatoid arthritis: another New World disease? Sem Arthritis Rheum 1994;23:289-94.
    • (1994) Sem Arthritis Rheum , vol.23 , pp. 289-294
    • Buchanan, W.W.1
  • 19
    • 0028218642 scopus 로고
    • Absence of lentiviral and human T cell leukemia viral sequences in patients with rheumatoid arthritis
    • Di Giovine FS, Bailly S, Bootman J, Almond N, Duff GW. Absence of lentiviral and human T cell leukemia viral sequences in patients with rheumatoid arthritis. Arthritis Rheum 1994;37:349-58.
    • (1994) Arthritis Rheum , vol.37 , pp. 349-358
    • Di Giovine, F.S.1    Bailly, S.2    Bootman, J.3    Almond, N.4    Duff, G.W.5
  • 20
    • 0023811772 scopus 로고
    • Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis
    • Cush JJ, Lipsky PE. Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis. Arthritis Rheum 1988;31:1230-8.
    • (1988) Arthritis Rheum , vol.31 , pp. 1230-1238
    • Cush, J.J.1    Lipsky, P.E.2
  • 21
    • 0000419276 scopus 로고
    • Rheumatoid synovitis and pannus
    • Klippel JH, Dieppe PA (eds). St Louis Mosby-Year Book Europe Limited
    • Firestein G. Rheumatoid synovitis and pannus. In: Klippel JH, Dieppe PA (eds). Rheumatology. St Louis Mosby-Year Book Europe Limited, 1995;12.1-12.30.
    • (1995) Rheumatology , pp. 121-1230
    • Firestein, G.1
  • 22
    • 0025801199 scopus 로고
    • Correlation of histopathological features of pannus with patterns of damage in different joints in rheumatoid arthritis
    • Allard SA, Muirden KD, Maini RN. Correlation of histopathological features of pannus with patterns of damage in different joints in rheumatoid arthritis. Ann Rheum Dis 1991;50:278-83.
    • (1991) Ann Rheum Dis , vol.50 , pp. 278-283
    • Allard, S.A.1    Muirden, K.D.2    Maini, R.N.3
  • 23
    • 0026802287 scopus 로고
    • Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair
    • Chu CQ, Field M, Allard S, Abney E, et al. Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair. Br J Rheumatol 1992;31:653-61.
    • (1992) Br J Rheumatol , vol.31 , pp. 653-661
    • Chu, C.Q.1    Field, M.2    Allard, S.3    Abney, E.4
  • 24
    • 0019486851 scopus 로고
    • Rheumatoid arthritis: A disease of T-lymphocyte/macrophage immunoregulation
    • Janossy G, Panayi G, Duke O, Bofill M, et al. Rheumatoid arthritis: a disease of T-lymphocyte/macrophage immunoregulation. Lancet 1981;ii:839-41.
    • (1981) Lancet , vol.2 , pp. 839-841
    • Janossy, G.1    Panayi, G.2    Duke, O.3    Bofill, M.4
  • 25
    • 0000785070 scopus 로고
    • Evidence in support of a self perpetuating HLA-DR dependent delayed type cell reaction in rheumatoid arthritis
    • Klareskog L, Forsum U, Scheynius A, Kabelitz D, Wigzell H. Evidence in support of a self perpetuating HLA-DR dependent delayed type cell reaction in rheumatoid arthritis. Proc Natl Acad Sci USA 1982;79:3632-6.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 3632-3636
    • Klareskog, L.1    Forsum, U.2    Scheynius, A.3    Kabelitz, D.4    Wigzell, H.5
  • 26
    • 0020442220 scopus 로고
    • Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity
    • Steeg PS, Moore RN, Johnson HM, Oppenheim JJ. Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity. J Exp Med 1982;156:1780-93.
    • (1982) J Exp Med , vol.156 , pp. 1780-1793
    • Steeg, P.S.1    Moore, R.N.2    Johnson, H.M.3    Oppenheim, J.J.4
  • 27
    • 0024554080 scopus 로고
    • Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions
    • Xu WD, Firestein GS, Taetle R, Kaushansky K, Zvaifler NJ. Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions. J Clin Invest 1989;83:876-82.
    • (1989) J Clin Invest , vol.83 , pp. 876-882
    • Xu, W.D.1    Firestein, G.S.2    Taetle, R.3    Kaushansky, K.4    Zvaifler, N.J.5
  • 28
    • 0023009755 scopus 로고
    • Effects of interferon gamma and tumour necrosis factor alpha on the expression of a Ia antigen on a murine macrophage cell line
    • Chang RJ, Lee SH. Effects of interferon gamma and tumour necrosis factor alpha on the expression of a Ia antigen on a murine macrophage cell line. J Immunol 1986;137:2853.
    • (1986) J Immunol , vol.137 , pp. 2853
    • Chang, R.J.1    Lee, S.H.2
  • 29
    • 0021033288 scopus 로고
    • Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease; relevance for autoimmunity
    • Hanafusa T, Pujol-Borrell R, Chiovato L, Russell RCG, et al. Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease; relevance for autoimmunity. Lancet 1983;ii: 1111-5.
    • (1983) Lancet , vol.2 , pp. 1111-1115
    • Hanafusa, T.1    Pujol-Borrell, R.2    Chiovato, L.3    Russell, R.C.G.4
  • 30
    • 0023002145 scopus 로고
    • Aberrant expression of HLA-DR antigens by insulin containing beta cells in recent onset Type I (insulin-dependent) diabetes mellitus
    • Foulis AK, Farquharson MA, Hardman R. Aberrant expression of HLA-DR antigens by insulin containing beta cells in recent onset Type I (insulin-dependent) diabetes mellitus. Diabetes 1986;35:1215-24.
    • (1986) Diabetes , vol.35 , pp. 1215-1224
    • Foulis, A.K.1    Farquharson, M.A.2    Hardman, R.3
  • 31
    • 0021916755 scopus 로고
    • Human T-cell clones from autoimmune thyroid glands: Specific recognition of autologous thyroid cells
    • Londei M, Bottazzo GF, Feldmann M. Human T-cell clones from autoimmune thyroid glands: specific recognition of autologous thyroid cells. Science 1985;228:85-9.
    • (1985) Science , vol.228 , pp. 85-89
    • Londei, M.1    Bottazzo, G.F.2    Feldmann, M.3
  • 33
    • 0029082506 scopus 로고
    • Identification of thyroid stimulating hormone receptor specific T cells in Graves' disease thyroid using antoantigen transfected EBV transformed B cell lines
    • Mullins RJ, Cohen SBA, Webb LMC, Chernajovsky Y, et al. Identification of thyroid stimulating hormone receptor specific T cells in Graves' disease thyroid using antoantigen transfected EBV transformed B cell lines. J Clin Invest 1995;96:30-7.
    • (1995) J Clin Invest , vol.96 , pp. 30-37
    • Mullins, R.J.1    Cohen, S.B.A.2    Webb, L.M.C.3    Chernajovsky, Y.4
  • 34
    • 0030046168 scopus 로고    scopus 로고
    • Human self-reactive T cell clones expressing identical TCR β chains differ in their ability to recognise a cryptic self-epitope
    • Quaratino S, Feldmann M, Dayan CM, Acuto O, Londei M. Human self-reactive T cell clones expressing identical TCR β chains differ in their ability to recognise a cryptic self-epitope. J Exp Med 1996;183:349-58.
    • (1996) J Exp Med , vol.183 , pp. 349-358
    • Quaratino, S.1    Feldmann, M.2    Dayan, C.M.3    Acuto, O.4    Londei, M.5
  • 35
    • 0022981391 scopus 로고
    • Thyroid autoimmunity in patients on long term therapy with leukocyte-derived interferon
    • Burman P, Totterman TH, Oberg K, Anders Karlsson F. Thyroid autoimmunity in patients on long term therapy with leukocyte-derived interferon. J Clin Endocrinol Metab 1986;63:1086-90.
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 1086-1090
    • Burman, P.1    Totterman, T.H.2    Oberg, K.3    Anders Karlsson, F.4
  • 36
    • 0023888654 scopus 로고
    • Hypothyroidism after treatment with interlenkin-2 and lymphokine-activated killer cells
    • Atkins MB, Mier JW, Parkinson DR, Gould JA, et al. Hypothyroidism after treatment with interlenkin-2 and lymphokine-activated killer cells. N Engl J Med 1988;318:1557-63.
    • (1988) N Engl J Med , vol.318 , pp. 1557-1563
    • Atkins, M.B.1    Mier, J.W.2    Parkinson, D.R.3    Gould, J.A.4
  • 37
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune svstcm
    • Panitch HS, Hirsch RL, Schindler J, Johnson KL. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune svstcm. Neurology 1987;37: 1097-1102.
    • (1987) Neurology , vol.37 , pp. 1097-1102
    • Panitch, H.S.1    Hirsch, R.L.2    Schindler, J.3    Johnson, K.L.4
  • 38
    • 0025108875 scopus 로고
    • Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ
    • Sarvetnick N, Shizuru J, Liggitt D, Martin L, et al. Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ. Nature 1990;346:844-7.
    • (1990) Nature , vol.346 , pp. 844-847
    • Sarvetnick, N.1    Shizuru, J.2    Liggitt, D.3    Martin, L.4
  • 39
    • 0027337691 scopus 로고
    • Induction of type-1 diabetes by interferon-α and transgenic mice
    • Stewart TA, Hultgren B, Huang X, Pitts-Meek S, et al. Induction of type-1 diabetes by interferon-α and transgenic mice. Science 1993;260:1942-7.
    • (1993) Science , vol.260 , pp. 1942-1947
    • Stewart, T.A.1    Hultgren, B.2    Huang, X.3    Pitts-Meek, S.4
  • 40
    • 0026594436 scopus 로고
    • Inflammation but not autoimmunity occurs in transgenic mice expressing constitutive levels of IL-2 in islet β cells
    • Allison J, Malcolm L, Chosich N, Miller JFAP. Inflammation but not autoimmunity occurs in transgenic mice expressing constitutive levels of IL-2 in islet β cells. Eur J Immunol 1992;22: 1115-21.
    • (1992) Eur J Immunol , vol.22 , pp. 1115-1121
    • Allison, J.1    Malcolm, L.2    Chosich, N.3    Miller, J.F.A.P.4
  • 41
    • 0028365499 scopus 로고
    • Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumour necrosis factor alpha leads to autoimmunity in transgenic mice
    • Guerder S, Picarella DE, Linsley PS, Flavell RA. Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumour necrosis factor alpha leads to autoimmunity in transgenic mice. Proc Natl Acad Sci USA 1994;91:5138-42.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5138-5142
    • Guerder, S.1    Picarella, D.E.2    Linsley, P.S.3    Flavell, R.A.4
  • 42
    • 0010688124 scopus 로고    scopus 로고
    • Cytokines in diabetes
    • Brennan FM, Feldmann M (eds). Austin, TX: RG Landes
    • Allison J, Miller J, Sarvetnick N. Cytokines in diabetes. In: Brennan FM, Feldmann M (eds). Cytokines in autoimmunity. Austin, TX: RG Landes, 1996:49-75.
    • (1996) Cytokines in Autoimmunity , pp. 49-75
    • Allison, J.1    Miller, J.2    Sarvetnick, N.3
  • 43
    • 0018955427 scopus 로고
    • The nucleotide sequence of human fibroblast interferon cDNA
    • Taniguchi T, Ohno S, Fujii-Kuriyama Y, Muramatsu H. The nucleotide sequence of human fibroblast interferon cDNA. Gene 1980;10:11-5.
    • (1980) Gene , vol.10 , pp. 11-15
    • Taniguchi, T.1    Ohno, S.2    Fujii-Kuriyama, Y.3    Muramatsu, H.4
  • 44
    • 0021751122 scopus 로고
    • Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumor necrosis factor activity
    • Gray PW, Aggarwal BB, Benton CV, Bringman TS, et al. Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumor necrosis factor activity. Nature 1984;312:721-4.
    • (1984) Nature , vol.312 , pp. 721-724
    • Gray, P.W.1    Aggarwal, B.B.2    Benton, C.V.3    Bringman, T.S.4
  • 46
    • 0023850364 scopus 로고
    • Detection of activated T cell products in the rheumatoid joint using cDNA probes to interleukin-2 (IL-2) IL-2 receptor and IFN-γ
    • Buchan G, Barrett K, Fujita T, Taniguchi T, et al. Detection of activated T cell products in the rheumatoid joint using cDNA probes to interleukin-2 (IL-2) IL-2 receptor and IFN-γ. Clin Exp Immunol 1988;71:295-301.
    • (1988) Clin Exp Immunol , vol.71 , pp. 295-301
    • Buchan, G.1    Barrett, K.2    Fujita, T.3    Taniguchi, T.4
  • 47
    • 0024678727 scopus 로고
    • Cytokine production in culture by cells isolated from the synovial membrane
    • Brennan FM, Chantry D, Jackson AM, Maini RN, Feldmann M. Cytokine production in culture by cells isolated from the synovial membrane. J Autoimmun 1989;2(Suppl):177-86.
    • (1989) J Autoimmun , vol.2 , Issue.SUPPL. , pp. 177-186
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.M.3    Maini, R.N.4    Feldmann, M.5
  • 48
    • 0020323211 scopus 로고
    • Interleukin-1 activity in the synovial fluid of patients with rheumatoid arthritis
    • Fontana A, Hentgartner H, Fehr K, Grob PJ, Cohen G. Interleukin-1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol Int 1982;2:49-56.
    • (1982) Rheumatol Int , vol.2 , pp. 49-56
    • Fontana, A.1    Hentgartner, H.2    Fehr, K.3    Grob, P.J.4    Cohen, G.5
  • 49
    • 0000609002 scopus 로고
    • Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint
    • Pettipher ER, Higgs GA, Henderson B. Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc Natl Acad Sci USA 1986;83:8749-53.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8749-8753
    • Pettipher, E.R.1    Higgs, G.A.2    Henderson, B.3
  • 50
    • 0022394427 scopus 로고
    • Purification of two immunologically different leucocyte proteins that cause cartilage resorption lymphocyte activation and fever
    • Saklatvala J, Sarsfield SJ, Townsend Y. Purification of two immunologically different leucocyte proteins that cause cartilage resorption lymphocyte activation and fever. J Exp Med 1985;162:1208-15.
    • (1985) J Exp Med , vol.162 , pp. 1208-1215
    • Saklatvala, J.1    Sarsfield, S.J.2    Townsend, Y.3
  • 51
    • 0024549356 scopus 로고
    • Mechanism of immune complex mediated damage; induction of interleukin 1 by immune complexes and synergy with interferon γ and tumour necrosis factor α
    • Chantry D, Winearls CG, Maini RN, Feldmann M. Mechanism of immune complex mediated damage; induction of interleukin 1 by immune complexes and synergy with interferon γ and tumour necrosis factor α. Eur J Immunol 1989;19:189-92.
    • (1989) Eur J Immunol , vol.19 , pp. 189-192
    • Chantry, D.1    Winearls, C.G.2    Maini, R.N.3    Feldmann, M.4
  • 52
    • 0022472749 scopus 로고
    • Tumour necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1
    • Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, et al. Tumour necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med 1986;163: 1433-50.
    • (1986) J Exp Med , vol.163 , pp. 1433-1450
    • Dinarello, C.A.1    Cannon, J.G.2    Wolff, S.M.3    Bernheim, H.A.4
  • 53
    • 0022441214 scopus 로고
    • Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage
    • Saklatvala J. Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 1986; 322:547-9.
    • (1986) Nature , vol.322 , pp. 547-549
    • Saklatvala, J.1
  • 54
    • 0025939257 scopus 로고
    • Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor-α
    • Haworth C, Brennan FM, Chantry D, Turner M, et al. Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-α. Eur J Immunol 1991;21:2575-9.
    • (1991) Eur J Immunol , vol.21 , pp. 2575-2579
    • Haworth, C.1    Brennan, F.M.2    Chantry, D.3    Turner, M.4
  • 55
    • 0029617952 scopus 로고
    • Blockade of TNFα with chimeric anti-TNFα monoclonal antibody, cA2 reduces IL-6 and IL-8 release in RA mononuclear cultures: A comparison with IL-1ra
    • Butler D, Maini RN, Feldmann M, Brennan FM. Blockade of TNFα with chimeric anti-TNFα monoclonal antibody, cA2 reduces IL-6 and IL-8 release in RA mononuclear cultures: a comparison with IL-1ra. Eur Cytokine Network 1995;6:225-30.
    • (1995) Eur Cytokine Network , vol.6 , pp. 225-230
    • Butler, D.1    Maini, R.N.2    Feldmann, M.3    Brennan, F.M.4
  • 56
    • 0024513152 scopus 로고
    • Cachectin/tumour necrosis factor
    • Tracey KJ, Vlassara H, Cerami A. Cachectin/tumour necrosis factor. Lancet 1989;i:1122-6.
    • (1989) Lancet , vol.1 , pp. 1122-1126
    • Tracey, K.J.1    Vlassara, H.2    Cerami, A.3
  • 57
    • 0026091413 scopus 로고
    • Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
    • Chu CQ, Field M, Feldmann M, Maini RN. Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 1991;34:1125-32.
    • (1991) Arthritis Rheum , vol.34 , pp. 1125-1132
    • Chu, C.Q.1    Field, M.2    Feldmann, M.3    Maini, R.N.4
  • 58
    • 0025166982 scopus 로고
    • Low levels of interleukin-4 and high levels of transforming growth factor β in rheumatoid synovitis
    • Miossec P, Naviliat M, D'Angeac AD, Sany J, Banchereau J. Low levels of interleukin-4 and high levels of transforming growth factor β in rheumatoid synovitis. Arthritis Rheum 1990;33:1180-7.
    • (1990) Arthritis Rheum , vol.33 , pp. 1180-1187
    • Miossec, P.1    Naviliat, M.2    D'Angeac, A.D.3    Sany, J.4    Banchereau, J.5
  • 59
    • 0024541065 scopus 로고
    • Active and latent forms of transforming growth factor β activity in synovial effusions
    • Fava R, Olsen N, Keski-Oja J, Moses H, Pincus T. Active and latent forms of transforming growth factor β activity in synovial effusions. J Exp Med 1989;169:291-6.
    • (1989) J Exp Med , vol.169 , pp. 291-296
    • Fava, R.1    Olsen, N.2    Keski-Oja, J.3    Moses, H.4    Pincus, T.5
  • 60
    • 0028226993 scopus 로고
    • Immunoregulatory role of interleukin (IL-10) in rheumatoid arthritis
    • Katsikis P, Chu CQ, Brennan FM, Maini RN, Feldman M. Immunoregulatory role of interleukin (IL-10) in rheumatoid arthritis. J Exp Med 1994;179:1517-27.
    • (1994) J Exp Med , vol.179 , pp. 1517-1527
    • Katsikis, P.1    Chu, C.Q.2    Brennan, F.M.3    Maini, R.N.4    Feldman, M.5
  • 61
    • 0026749602 scopus 로고
    • Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints
    • Brennan FM, Gibbons DL, Mitchell T, Cope AP, et al. Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints. Eur J Immunol 1992;22:1907-12.
    • (1992) Eur J Immunol , vol.22 , pp. 1907-1912
    • Brennan, F.M.1    Gibbons, D.L.2    Mitchell, T.3    Cope, A.P.4
  • 62
    • 0023688176 scopus 로고
    • The interleukin 2 receptor
    • Smith KA. The interleukin 2 receptor. Adv Immunol 1988;42: 165-74.
    • (1988) Adv Immunol , vol.42 , pp. 165-174
    • Smith, K.A.1
  • 63
    • 0026802524 scopus 로고
    • Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha
    • Deleuran BW, Chu CQ Field M, Brennan FM, et al. Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha. Arthritis Rheum 1992;35:1170-8.
    • (1992) Arthritis Rheum , vol.35 , pp. 1170-1178
    • Deleuran, B.W.1    Chu, C.Q.2    Field, M.3    Brennan, F.M.4
  • 64
    • 0027268043 scopus 로고
    • Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus
    • Aderka D, Wysenbeek A, Engelmann H, Cope AP, et al. Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus. Arthritis Rheum 1993;36:1111-21.
    • (1993) Arthritis Rheum , vol.36 , pp. 1111-1121
    • Aderka, D.1    Wysenbeek, A.2    Engelmann, H.3    Cope, A.P.4
  • 65
    • 0026806992 scopus 로고
    • Soluble-tumour necrosis factor (TNF) receptors are increased in the sera and synovial fluids of patients with rheumatic diseases
    • Cope A, Aderka D, Doherty M, Engelmann H, et al. Soluble-tumour necrosis factor (TNF) receptors are increased in the sera and synovial fluids of patients with rheumatic diseases. Arthritis Rheum 1992;35:1160-9.
    • (1992) Arthritis Rheum , vol.35 , pp. 1160-1169
    • Cope, A.1    Aderka, D.2    Doherty, M.3    Engelmann, H.4
  • 66
    • 0029077690 scopus 로고
    • TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: Evidence of feedback control of TNFα action
    • Brennan FM, Gibbons D, Cope A, Katsikis P, et al. TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: evidence of feedback control of TNFα action. Scand J Immunol 1995;42:158-65.
    • (1995) Scand J Immunol , vol.42 , pp. 158-165
    • Brennan, F.M.1    Gibbons, D.2    Cope, A.3    Katsikis, P.4
  • 67
    • 0026644298 scopus 로고
    • Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams RO, Feldman M, Maini RN. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 1992;89:9784-8.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9784-9788
    • Williams, R.O.1    Feldman, M.2    Maini, R.N.3
  • 68
    • 0026656850 scopus 로고
    • Involvement of endogenous tumour necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice
    • Thorbecke GJ, Shah R, Leu CH, Kuruvilla AP, et al. Involvement of endogenous tumour necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice. Proc Natl Acad Sci USA 1992;89:7375-9.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7375-7379
    • Thorbecke, G.J.1    Shah, R.2    Leu, C.H.3    Kuruvilla, A.P.4
  • 69
    • 0026677361 scopus 로고
    • Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor
    • Piguet PF, Grau GE, Vesin C, Loetscher H, et al. Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology? 1992;77:510-4.
    • (1992) Immunology? , vol.77 , pp. 510-514
    • Piguet, P.F.1    Grau, G.E.2    Vesin, C.3    Loetscher, H.4
  • 70
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer J, Probert L, Cazlaris H, Georgopoulos S, et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J 1991;10:4025-31.
    • (1991) EMBO J , vol.10 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3    Georgopoulos, S.4
  • 71
    • 0027361432 scopus 로고
    • Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
    • Knight DM, Trinh H, Le J, Siegel S, et al. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol 1993;30:1443-53.
    • (1993) Mol Immunol , vol.30 , pp. 1443-1453
    • Knight, D.M.1    Trinh, H.2    Le, J.3    Siegel, S.4
  • 72
    • 0027438710 scopus 로고
    • Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to TNFα
    • Elliott MJ, Maini RN, Feldmann M, Long-Fox A, et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to TNFα. Arthritis Rheum 1993;36:1681-90.
    • (1993) Arthritis Rheum , vol.36 , pp. 1681-1690
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Long-Fox, A.4
  • 73
    • 0029836261 scopus 로고    scopus 로고
    • The Croonian Lecture 1995. The role of cytokines in rheumatoid arthritis
    • Maini RN. The Croonian Lecture 1995. The role of cytokines in rheumatoid arthritis. J R Coll Physicians Lond 1996;30:344-51.
    • (1996) J R Coll Physicians Lond , vol.30 , pp. 344-351
    • Maini, R.N.1
  • 74
    • 0028990467 scopus 로고
    • Monoclonal anti TNFα antibody as a probe of pathogenesis and therapy of rheumatoid disease
    • Maini RN, Elliott MJ, Brennan FM, Williams RO, et al. Monoclonal anti TNFα antibody as a probe of pathogenesis and therapy of rheumatoid disease. Immunol Rev 1995;144:195-223.
    • (1995) Immunol Rev , vol.144 , pp. 195-223
    • Maini, R.N.1    Elliott, M.J.2    Brennan, F.M.3    Williams, R.O.4
  • 76
    • 0028143212 scopus 로고
    • Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldman M, Long-Fox A, et al. Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis. Lancet 1994;344:1125-7.
    • (1994) Lancet , vol.344 , pp. 1125-1127
    • Elliott, M.J.1    Maini, R.N.2    Feldman, M.3    Long-Fox, A.4
  • 77
    • 0028143211 scopus 로고
    • Randomised double blind comparison of a chimaeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldman M, Kalden JR, et al. Randomised double blind comparison of a chimaeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldman, M.3    Kalden, J.R.4
  • 78
    • 0029044028 scopus 로고
    • The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CD571) in rheumatoid arthritis
    • Rankin ECC, Choy EHS, Kassimos D, Kingsley GH, et al. The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CD571) in rheumatoid arthritis. Br J Rheumatol 1995;34:334-42.
    • (1995) Br J Rheumatol , vol.34 , pp. 334-342
    • Rankin, E.C.C.1    Choy, E.H.S.2    Kassimos, D.3    Kingsley, G.H.4
  • 79
    • 0027231774 scopus 로고
    • Tumour necrosis factor antibody treatment in Crohn's disease
    • Derkx R, Taminiau RS, Stronkhorst A, Wortel C, et al. Tumour necrosis factor antibody treatment in Crohn's disease. Lancet 1993;342:173-4.
    • (1993) Lancet , vol.342 , pp. 173-174
    • Derkx, R.1    Taminiau, R.S.2    Stronkhorst, A.3    Wortel, C.4
  • 80
    • 0029050742 scopus 로고
    • Treatment of Crohn's disease with anti-tumour necrosis factor chimeric monoclonal antibody (cA2)
    • Van Dullemen HM, Van Deventer SJH, Homes DW, Bijl HA, et al. Treatment of Crohn's disease with anti-tumour necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology 1995;109:129-35.
    • (1995) Gastroenterology , vol.109 , pp. 129-135
    • Van Dullemen, H.M.1    Van Deventer, S.J.H.2    Homes, D.W.3    Bijl, H.A.4
  • 81
    • 0025000863 scopus 로고
    • An antibody to lymphotoxin and tumour necrosis factor prevents transfer of experimental allergic encephalomyelitis
    • Ruddle NH, Bergman CM, McGrath KM, Lingenheld EG, et al. An antibody to lymphotoxin and tumour necrosis factor prevents transfer of experimental allergic encephalomyelitis. J Exp Med 1990;172:1193-200.
    • (1990) J Exp Med , vol.172 , pp. 1193-1200
    • Ruddle, N.H.1    Bergman, C.M.2    McGrath, K.M.3    Lingenheld, E.G.4
  • 82
    • 0028066844 scopus 로고
    • Control of established experimental allergic encephalomyelitis by inhibition of tumour necrosis factor activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins
    • Baker D, Butler D, Scallon BJ, O'Neill JK, et al. Control of established experimental allergic encephalomyelitis by inhibition of tumour necrosis factor activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins. Eur J Immunol 1994;24:2040-8.
    • (1994) Eur J Immunol , vol.24 , pp. 2040-2048
    • Baker, D.1    Butler, D.2    Scallon, B.J.3    O'Neill, J.K.4
  • 83
    • 0028955945 scopus 로고
    • The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis
    • Sommer N, Loschmann P-A, Northoff GH, Weller M, et al. The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis. Nat Med 1995;1:244-8.
    • (1995) Nat Med , vol.1 , pp. 244-248
    • Sommer, N.1    Loschmann, P.-A.2    Northoff, G.H.3    Weller, M.4
  • 84
    • 0028912608 scopus 로고
    • Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor
    • Genain CP, Roberts T, Davis RL, Nguyen M-H, et al. Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor. Proc Natl Acad Sci USA 1995;92:3601-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3601-3605
    • Genain, C.P.1    Roberts, T.2    Davis, R.L.3    Nguyen, M.-H.4
  • 85
    • 0030013609 scopus 로고    scopus 로고
    • Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor α antibody in rheumatoid arthritis
    • Paleolog EM, Hunt M, Elliott MJ, Feldmann M, et al. Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor α antibody in rheumatoid arthritis. Arthritis Rheum 1996;39:1082-91.
    • (1996) Arthritis Rheum , vol.39 , pp. 1082-1091
    • Paleolog, E.M.1    Hunt, M.2    Elliott, M.J.3    Feldmann, M.4
  • 86
    • 0028226982 scopus 로고
    • Synergy between anti-CD4 and anti-TNF in the amelioration of established collagen-induced arthritis
    • Williams RO, Mason LJ, Feldmann M, Maini RN. Synergy between anti-CD4 and anti-TNF in the amelioration of established collagen-induced arthritis. Proc Natl Acad Sci USA 1994;91:2762-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2762-2766
    • Williams, R.O.1    Mason, L.J.2    Feldmann, M.3    Maini, R.N.4


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