Mad cows meet mad yeast: The prion hypothesis

Molecular Psychiatry

Volumn 1, Issue 5, 1996, Pages 376-379

  Lindquist, S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Heat shock protein 104; Neurodegenerative disease; Prion; Protein synthesis fidelity; Spongiform encephalopathies

Indexed keywords

ANIMAL; BOVINE SPONGIFORM ENCEPHALOPATHY; CATTLE; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PRION; REVIEW; YEAST;

ANIMALS; CATTLE; ENCEPHALOPATHY, BOVINE SPONGIFORM; PRIONS; YEASTS;

EID: 0030275513     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Gambetti P. Fatal familial insommnia and familial Creutzfeldt-Jakob disease: a tale of two diseases with the same genetic mutation. Micro & Immuno 1996; 207: 19-21.
2. Lansbury PTJ, Caughey B. The chemistry of scrapie infection: implications of the 'ice 9' metaphor. Curr Biol 1995; 2: 1-5.
3. Scott MRD, Telling GC, Prusiner SB. Transgenetics and gene targeting in studies of prion diseases. Micro & Immuno 1996; 207: 95-119.
4. Weissman C. Molecular biology of prion diseases. Trends Cell Biol 1994; 4: 10-14.
5. Alper T, Cramp WA, Haig DA, Clarke MC. Does the agent of scrapie replicate without nucleic acid? Nature 1967; 214: 764-766.
6. Pattison IH, Jones KM. The possible nature of the transmissible agent of scrapie. Vet Rec 1967; 80: 2-9.
7. Griffith JS. Self-replication and scrapie. Nature 1967; 215: 1043-1044.
8. Lacroute F. Non-Mendelian mutation allowing ureidosuccinic acid uptake in yeast. J Bacteriol 1971; 106: 519-522.
9. Aigle M, Lacroute F. Genetical aspects of [URE3], a non-mitochondrial cytoplasmically inherited mutation in yeast. Molec Gen Genet 1975; 136: 327-335.
10. Cox BS. Ψ, a cytoplasmic suppressor of super-suppressor in yeast: Heredity 1965; 20: 505-521.
11. Cox BS, Tuite MF, McLaughlin CS. The PSI factor of yeast: a problem in inheritance. Yeast 1988; 4: 159-179.
12. Wickner RB, Masison DC, Edskes HK. [PSI] and [URE3] as yeast prions. Yeast 1995; 11: 1671-1685.
13. Stansfield I, Jones KM, Kushnirov VV et al. The products of the SUP45 (cRF1) and SUP35 genes interact to mediate translation termination in Saccharomvces cerevisiae. EMBO J 1995; 14: 4365-4373.
14. Stansfield I, Tuite MF. Polypeptide chain termination in Saccharomyces cerevisiae. Curr Genet 1994; 25: 385-395.
15. Chernoff YO, Derkach IL, Inge-Vechtomov SG. Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomvces cerevisiae. Curr Genet 1993; 24: 268-270.
16. Ter-Avanesyan MD, Kushnirov VV, Dagkesamanskaya AR et al. Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non-overlapping functional regions in the encoded protein. Mol Microb 1995; 7: 683-692.
17. Wickner RB. [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science 1994; 264: 566-569.
18. Doel SM, McCready SJ, Nierras CR, Cox BS. The dominant PNM2-mutation which eliminates the factor of Saccharomyces cerevisiae is the result of a missense mutation in the SUP35 gene. Genetics 1994; 137: 659-670.
19. Chernoff YO, Lindquist SL, Ono-B-I, Inge-Vechtomov SG, Liobman SW. Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]. Science 1995; 268: 880-883.
20. Sanchez Y, Lindquist SL. HSP104 required for induced thermotolerance. Science 1990; 248: 1112-1115.
21. Parsell DA, Lindquist S. Heat shock proteins and stress tolerance. In: Morimoto RI, Tissieres A. Geogopoulos C (eds). The Biology of Heat Shock Proteins and Molecular Chaperones. Cold Spring Harbor Laboratory Press: New York, 1994, pp 457-494.
22. Lindquist S, Patino MM, Chernoff YO et al. The role of Hsp104 in stress tolerance and [PSI+] propagation in Saccharomyces cerevisiae. Cold Spring Harbor Symposia on Quantitative Biology. CSH Laboratory Press: Cold Spring Harbor, NY, 1995, pp 451-460.
23. Patino MM, Liu J-J, Glover JR, Lindquist S. Support for the prion hypothesis for inheritance of a phenotypic trait in yeast. Science 1996; 273: 622-626.
24. Tuite MF, Cox BS. Ultraviolet mutagenesis studies of [psi], a cytoplasmic determinant of Saccharomyces cerevisiae. Genetics 1980; 95: 611-630.
25. Kobayashi N, McEntee K. Evidence for a heat shock transcription factor-independent mechanism for heat shock induction of transcription in Saccharomvces cerevisiae. Proc Natl Acad Sci USA 1990; 87: 6550-6554.
26. Derkatch IL, Chernoff YO, Kushnirov VV, Inge-Vechtomov SG, Liebman SW. Genesis and variability of prion-like [PSI] factors in Saccharomyces cerevisiae. Genetics 1996 (in press).
27. Paushkin SV, Kushnirov VV, Smirnov VN, Ter-Avanesyan MD. Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor. EMBO J 1996; 15: 3127-3134.
28. Prusiner S. Molecular biology of prion diseases. Science 1991; 252: 1515-1522.
29. Bruce ME, Fraser H. Scrapie strain variation and its implications. Curr Top Microbiol Immunol 1991; 172: 125-138.