Use of the chemical structure of peptides as the starting point to design nonpeptide agonists and antagonists at peptide receptors: Examples with cholecystokinin and tachykinins

Bioorganic and Medicinal Chemistry

Volumn 4, Issue 10, 1996, Pages 1573-1576

  Horwell, David C ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 [[2 [2 [[(2 ADAMANTYLOXY)CARBONYL]AMINO] 3 (1H INDOL 3 YL) 2 METHYLPROPIONAMIDO] 1 PHENYLETHYL]AMINO] 4 OXOBUTYRIC ACID MEGLUMINE; ALPHA METHYL N [(TRICYCLO[3.3.1.1 3,7]DEC 2 YLOXY)CARBONYL]TRYPTOPHYL DEXTRO 3 BENZYL BETA ALANINE; CHOLECYSTOKININ RECEPTOR; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; CHOLECYSTOKININ RECEPTOR STIMULATING AGENT; PD 135158; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR AGONIST; TACHYKININ RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONFORMATION; DRUG ACTIVITY; DRUG DESIGN; PROTEIN STRUCTURE; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0030273630     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/0968-0896(95)00190-5     Document Type: Review

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