The influence of molecular diagnostic procedures on the surgical treatment of malignant diseases;Der einfluß molekularer diagnostikverfahren auf die chirurgische therapie maligner erkrankungen

Chirurg

Volumn 67, Issue 10, 1996, Pages 967-979

  Von Knebel Doeberitz, M ^a,b   Gebert, J ^a   Herfarth, Ch ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Hereditary cancer; Minimal residual disease; Molecular diagnosis

Indexed keywords

CELL TRANSFORMATION; CHROMOSOME ABERRATION; FAMILIAL CANCER; GENETICS; HUMAN; MINIMAL RESIDUAL DISEASE; MOLECULAR CLONING; MULTIMODALITY CANCER THERAPY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRECANCER; PROGNOSIS; REVIEW; TUMOR SUPPRESSOR GENE;

CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME ABERRATIONS; CLONING, MOLECULAR; COMBINED MODALITY THERAPY; DNA MUTATIONAL ANALYSIS; GENES, TUMOR SUPPRESSOR; HUMANS; NEOPLASM, RESIDUAL; NEOPLASTIC SYNDROMES, HEREDITARY; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS; PROGNOSIS;

EID: 0030254699     PISSN: 00094722     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00002514     Document Type: Article

References (74)

1. Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, et al (1993) Clues to the pathogenesis of familial colorectal cancer. Science 260: 812
2. Aarnio M, Mecklin J-P, Aaltonen LA, Nyström-Lahti M, Järvinen HJ (1995) Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome. Int J Cancer 64: 430
3. Aas T, Borresen AL, Geisler S, Smith-Sorensen, et al (1996) Specific p53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients. Nat Med 2: 811
4. August DA, Ottow RT, Sugarbaker PH (1984) Clinical perspectives on human colorectal cancer metastases. Cancer Metastasis Rev 3: 303
5. Bodmer W, Bishop T, Karran P (1994) Genetic steps in colorectal cancer. Nat Genet 6: 217
6. Bos JL (1990) Ras gene mutations and human cancer. In: Cossman J (ed) Molecular biology of human cancer. Elsevier, Amsterdam New York, p 273
7. Brennan JA, Mao L, Hruban RH, et al (1995) Molecular assesment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 332: 429
8. Brossart P, Schmier J, Krüger S, Willhauck M, et al (1995) A PCR-based semiquantitative assessment of malignant melanoma cells in peripheral blood. Cancer Res 55: 4065
9. Bunyan DJ, Shea-Simonds J, Reck AC, Finnis D, Eccles DM (1995) Genotype-phenotype correlations of new causative APC gene mutations in patients with familial adenomatous polyposis. J Med Genet 32: 728
10. Burchill SA, Bradbury MF, Pittman K, Southgate J, et al (1994) Detection of epithelial cancer cells in peripheral blood by reverse transcriptase polymerase chain reaction. Br J Cancer 71: 278
11. Caldas C, Hahn SA, Hruban RH, Redston MS, et al (1994) Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. Cancer Res 54: 3568
12. Caspari R, Friedl W, Mandl M, Moslem G, et al (1994) Familial adenomatous polyposis: mutation at codon 1309 and early onset of colon cancer. Lancet 343: 629
13. Chi DD, Toshima K, Donis-Keller H, Wells SA Jr. (1994) Predictive testing for multiple endocrine neoplasia type 2A (MEN 2A) based on the detection of mutations inthe RET protooncogene. Surgery 116: 124
14. Decker RA, Peacock ML, Borst MJ, Sweet JD, Thompson NW (1995) Progress in genetic screening of multiple endocrine neoplasia type 2A: is calcitonin testing obsolete? Surgery 118: 257
15. Deguchi T, Doi T, Ehara H, Ito S, et al (1993) Detection of micrometastatic prostate cancer cells inlymph nodes by reverse transcriptase polymerase chain reaction. Cancer Res 53: 5350
16. Delattre O, Zucman J, Melot T, Garau XS, et al (1994) The Ewing family of tumors - a subgroup of small round cell tumors defined by specific chimeric transcripts. N Engl J Med 331: 294
17. Diel IJ, Kaufmann M, Groener R, Costa SD, et al (1992) Detection of tumor cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis. J Clin Oncol 10: 1534
18. Evans DG (1995) Genetic testing for cancer predisposition: need and demand. J Med Genet 32: 161
19. Friedl W, Möslein G, Jaeger K, Herfarth Ch, Propping P (1991) Familiäre adenomatöse Polyposis. Paradigma einer therapierbaren genetischen Krankheit. Dtsch Ärztebl 88: A-1261
20. Frilling A, Hoppner W, Eng C, Mulligan L, et al (1995) Presymptomatic genetic screening in families with multiple endocrine neoplasia type 2. J Mol Med 73: 229
21. Gerhard M, Juhl H, Kalthoff H, Schreiber HW, et al (1994) Specific detection if carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 12: 725
22. Giardiello FM, Krush AJ, Petersen GM, Booker SV, et al (1994) Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC mutation. Gastroenterology 106: 1542
23. 22a. Goodfellow PJ, Wells SA Jr. (1995) RET Gene and its implications for cancer. J Natl Canc Inst 87: 1515
24. Greenson JK, Isenhart CE, Rice R, Mojzisik C, et al (1994) Identification of occult micrometastases in pericolic lymph nodes of Duke's B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Correlation with long-term survival. Cancer 73: 563
25. Hartwell LH, Kastan MB (1994) Cell cycle control and cancer. Science 266: 1821
26. Hemminki A, Peltomäki P, Mecjlin J-P, Järvinen H, et al (1994) Loss of the wild type MLH1 gene is a feature of hereditary non-polyposis colorectal cancer. Nat Genet 8: 405
27. Jass JR, Cottier DS, Jeevaratnam P, Pokos V, et al (1995) Diagnostic use of microsatellite instability in hereditary non-polyposis colorectal cancer. Lancet 346: 1200
28. Jen J, Hoguen K, Piantadosi S, Liu Z-F, et al (1994) Allelic loss of chromosome 18q and prognosis in colorectal cancer. N Engl J Med 331: 213
29. Johnson PWM, Burchill SA, Selby PJ (1995) The molecular detection of circulating tumour cells. Br J Cancer 72: 268
30. Kahn SM, Jiang W, Culbertson TA, Weinstein IB, et al (1991) Rapid and sensitive nonradioactive detection of mutant K-ras genes via "enriched" PCR amplification. Oncogene 6: 1079
31. Kinzler KW, Nilbert MC, Su L-K, Vogelstein B, et al (1991) Identification of FAP locus genes from chromosome 5q21. Science 253: 661
32. Knudson AG (1971) Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820
33. Kolodner RD (1995) Mismatch repair: mechanisms and relationship to cancer susceptibility. Trends Biol Sci 29: 397
34. Lazar V, Grandjouan S, Bognel C, Couturier D, et al (1994) Accumulation of multiple mutations in tumor suppressor genes during colorectal tumorigenesis in HNPCC patients. Hum Mol Genet 3: 2257
35. Leather AJM, Kocjyan G, Savage F, Hu W, et al (1994) Detection of free malignant cells in the peritoneal cavity and after resection of colorectal cancer. Dis Colon Rectum 37: 814
36. Lee JM, Bernstein A (1995) Apoptosis, cancer and the p53 tumor suppressor gene. Cancer Metastasis Rev 14: 149
37. Lemoine NR, Jain S, Hughes C, Staddon SL, et al (1992) Ki-ras oncogene activation in preinvasive pancreatic cancer. Gastroenterology 102: 230
38. Lindemann F, Schlimok G, Dirschedl P, Witte J, Riethmüller G (1992) Prognostic significance of micrometastatic tumor cells in bone marrow cells in bone marrow of colorectal cancer patients. Lancet 340: 685
39. Liu B, Parsons R, Papadopoulos N, et al (1996) Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Med 2: 169
40. Loeb A (1991) Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51: 3075
41. Luce MC, Marra G, Chauhan DP, Laghi L, et al (1995) In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer. Gastroenterology 109: 1368
42. Lynch HT, Smyrk T, Watson P, et al (1993) Genetics, natural history, tumor spectrum, and pathology of hereditary non-polpyposis colorectal cancer: an updated review. Gastroenterology 104: 1535
43. Lynch TH, Smyrk T, Lynch JF (1996) Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome). Int J Cancer 69: 38
44. Mak YF, Ponder BAJ (1996) RET oncogene. Curr Opin Genet Dev 6: 82
45. Mao L, Hruban RH, Boyle JO, Tockman M, Sidransky D (1994) Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. Cancer Res 54: 1634
46. Mattano LA, Moss TJ, Emerson SG (1992) Sensitive detection of rare circulating neuroblastoma cells by reverse transcriptase-polymerase chain reaction. Cancer Res 52: 4701
47. Markowitz S, Wang J, Myeroff L, Parsons R, et al (1995) Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 268: 1336
48. Mills NE, Fishman CL, Scholes J, Anderson SE, et al (1995) Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis. J Natl Cancer Inst 87: 1056
49. Moreno JG, Croce CM, Fischer R, Monne M, et al (1992) Detection of hematogenous micrometastisis in patients with prostate cancer. Cancer Res 52: 6110
50. Nagase H, Nakamura Y (1993) Mutations of APC (the adenomatous polyposis coli) gene. Hum Mutat 2: 425
51. Neumaier M, Gerhard M, Wagener C (1995) Diagnosis of micrometastases by the amplification of tissue-specific genes. Gene 159: 43
52. Pantel K, Izbicki J, Passlick B, Angstwurm M, et al (1996) Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet 347: 649
53. Pasini B, Ceccherini I, Romeo G (1996) RET mutations in human disease. Trends Genet 12: 138
54. Peter M, Magdelenat H, Michon J, Melot T, et al (1995) Sensitive detection of occulut Ewing's cells by the reverse transcriptase-polymerase chain reaction. Br J Cancer 72: 96
55. Powell SM, Petersen GM, Krush AJ, Booker S, et al (1993) Molecular diagnosis of familial adenomatous polyposis. N Engl J Med 329: 1982
56. Röher HD, Simon D, Goretzki PE, Höppner W, et al (1995) Die prophylaktische Radikaloperation des C-Zell-Carcinoms beim MEN-II-Syndrom auf der Grundlage des genetischen Screening. Chirurg 66: 1196
57. Rubinfeld B, Souza B, Albert I, Müller O, et al (1993) Association of the APC gene product with β-catenin. Science 262: 1731
58. Schackert HK, Gebert J, Ansorge W, Herfarth Ch (1993) Molekulare Grundlagen der Carcinogenese. Bedeutung für die Prävention und Früherkennung solider maligner Tumoren. Chirurg 64: 669
59. Schoenfeld A, Luqmani E, Smith D, Oreilly S, et al (1994) Detection of breast cancer micrometastases in axillary lymphnodes by using polymerase chain reaction. Cancer Res 54: 2986
60. Shibata D, Navidi W, Salovaara R, Li Z-H, Aaltonen LA (1996) Somatic microsatellite mutations as molecular tumor clocks. Nat Med 2: 676
61. Sidransky D, Tokino T, Hamilton SR, Kinzler KW, et al (1992) Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 256: 102
62. Smith KJ, Levy DB, Maupin P, Pollard TD, et al (1994) Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res 54: 3672
63. Smith B, Selby P, Southgate J, Pittman K, et al (1991) Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet 338: 1227
64. Statement of the American Society of clinical oncology (1996) Genetic testing for cancer susceptibility. J Clin Oncol 14: 1730
65. Stork P, Loda M, Bosari S, Wiley B, et al (1991) Detection of K-ras mutations in pncreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction. Oncogene 6: 857
66. Tada M, Omata M, Kawai S, Saisho H, et al (1993) Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res 53: 2472
67. Thibodeau SN, Bren G, Schaid D (1993) Microsatellite instability in cancer of the proximal colon. Science 260: 816
68. Trümper LH, Bürger B, von Bonin F, Hintze A, et al (1994) Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions. Br J Cancer 70: 278
69. van der Luijt RB, Vasen HF, Tops CMJ, Breukel C, et al (1995) APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis. Hum Genet 96: 705
70. Vasen HFA, Mecklin JP, Meera-Khan P, Lynch HT (1991) The International Collaborative Group on Hereditary Non-polyposis Colorectal Cancer. Dis Colon Rectum 34: 424
71. Villa E, Dugani A, Rebecchi AM, Vignoli A, et al (1996) Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool. Gastroenterology 110: 1346
72. Wang X, Heller R, VanVoorhis N, Cruse CW, et al (1994) Detection of submicroscopic lymph node metastases with polymerase chain reaction in patients with malignant melanoma. Ann Surg 220: 768
73. Wells SA Jr, Chi DD, Toshima K, Dehner LP, et al (1994) Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A. Ann Surg 220: 237
74. Wooster R, Cleton-Jansen AM, Collins N, Mangion J, et al (1994) Instability of short tandem repeats (microsatellites) in human cancers Nat Genet 6: 152