Pharmacokinetic considerations in the camel (Camelus dromedarius): A review

Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology

Volumn 115, Issue 1, 1996, Pages 1-9

  Ali, B H ^a   Oukessou, M ^b   Bashir, A K ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b INSTITUT AGRONOMIQUE ET VÉTÉRINAIRE HASSAN II   (Morocco)

Author keywords

antibacterial agents; antiinflammatory agents; antiparasitic agents; camels; dehydration; pharmacokinetics

Indexed keywords

ALBENDAZOLE; ALBENDAZOLE SULFONE; ALBENDAZOLE SULFOXIDE; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIPARASITIC AGENT; CHLORAMPHENICOL; ENROFLOXACIN; FLUNIXIN; GENTAMICIN; ISOMETAMIDIUM CHLORIDE; IVERMECTIN; KANAMYCIN; KETOPROFEN; NETOBIMIN; NETOBIMIN SULFONE; OXYTETRACYCLINE; PENICILLIN G; PHENAZONE; PHENYLBUTAZONE; STREPTOMYCIN; SULFADIMIDINE; SULFAMETHOXYPYRIDAZINE; TOBRAMYCIN; TRICLABENDAZOLE; TRICLABENDAZOLE SULFONE; TRICLABENDAZOLE SULFOXIDE; TYLOSIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; CAMEL; DEHYDRATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; REVIEW; SPECIES DIFFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; ANTIPARASITIC AGENTS; BIOLOGICAL AVAILABILITY; CAMELS; DEHYDRATION; DOSE-RESPONSE RELATIONSHIP, DRUG; WATER DEPRIVATION;

EID: 0030250766     PISSN: 07428413     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0742-8413(96)00120-X     Document Type: Review

References (61)

1. 1. Abdel Hadi, A. A.; Wasfi, I. A.; Gadir, F. A.; Amiri, M. H.; Bashir, A. K.; Baggot, J. D. Pharmacokinetics of tobramycin in the camel. J. Vet. Pharmacol. Ther. 17:48-51;1994.
2. 2. Abdennebi, E. H.; Bousfiha, A.; Ben Goumi, M.; Oukessou, M. Etude de la pharmacocinetique et de la liaison aux proteins plasmatiques de la sulphamethoxypyridazine chez le dromedarie. Rev. Elev. Med. Pays Trop. 47:97-102;1994.
3. 3. Ali, B. H; El Sheikh, H. A. Some comparative aspects of drug metabolism in Nubian goats, desert sheep and dromedary camels. Comp. Biochem. Physiol. 101C:189-195;1992.
4. 4. Ali, B. H. Survey of some drugs commonly used in the camel. Vet. Res. Commun. 12:67-75;1988.
5. 5. Ali, B. H. Gentamicin nephrotoxicity in humans and animals: some recent research. Gen. Pharmac. 26:1477-1487;1995.
6. 6. Ali, B. H.; Cheng, Z.; Al Hadrami, G.; Bashir, A. K.; McKellar, Q. A. Comparative pharmokinetics of paracetamol (acetaminophen) and its sulphate and glucuronide metabolites in desert camels and goats. J. Vet. Pharmacol. Ther. In press; 1996.
7. 7. Ali, B. H.; Hassan, T. Preliminary phannacokinetic study of isometamidium chloride (samorin) in camels Res. Vet. Sci. 37:376-377:1984.
8. 8. Ali, B. H.; Hassan, T. Some observations on the toxicosis of isometamidium chloride (samorin) in camels. Vet. Hum. Toxicol. 28:424-426;1984.
9. 9. Ali, B. H.; Hassan, T.; Malik, K. H. A clinical evaluation of samorin in Trypanosoma evansi infections in Camelus dromedarius. J. Vet. Pharmacol. Ther. 8:208-210;1985.
10. 10. Anderson, K. L.; Davis, C. A. M.; Davis, L. E.; Bass, V. D. Pharmacokinetics of flunixin meglumine in lactating cattle after single and multiple intramuscular and intravenous administration. Am. J. Vet. Res. 51:1464-1467;1990.
11. 11. Appel, G. B. Aminoglycoside nephrotoxicity. Am. J. Med. 88(Supp3C):165-205;1990.
12. 12. Badri, M.; Oukessou, M.; Sutra, J. F.; Galtier, P; Alvinerie, M. Pharmacokinetics of ivermectin in the camel Camelus dromedarius. Vet. Res. In press; 1996.
13. 13. Bennett, W. M. Mechanism of aminoglycoside nephrotoxicity. Clin. Exp. Pharmacol. Physiol. 16:1-6;1989.
14. 14. Ben-Zvi, Z; Rubin, M.; Van Creveld, C.; Yagil, R. Antipyrine disposition in the dehydrated camel. J. Vet. Pharmacol. Ther. 18:137-140;1995.
15. 15. Ben-Zvi, Z.; Van Creveld, C.; Yagil, R. Liver function and protein binding in camels. Comp. Biochem, Physiol. 93(A): 349-352;1989.
16. 16. Braide, V. B.; Eghiaruwa, K. I. Isometamidium residues in goats tissues after parenteral administration. Res. Vet. Sci. 29: 111-113;1980.
17. 17. Chiu, P. J. S.; Long, J. F. Effects of dehydration on gentamicin excretion and renal accumulation in furosemide-treated rats. Antimicrob. Agents Chemother. 14:214-217;1978.
18. 18. Damanhouri, Z. A.; Tayeh, O. S. A comparative study of liver mixed function oxidases in camels, guinea pigs and rats. Comp. Biochem. Physiol. 105C:487-491;1993.
19. 19. Delatour, P.; Ouhsine, A.; Benoit, E. Comparative pharmacokinetics of netobimin and albendazole in the one-humped camel (Camelus dromedarius). Br. Vet. J. 145:478-482; 1989.
20. 20. El Gendi, Y.; El-Sayed, M. G.; Atef, M.; Hussein, A. Z. Pharmacokinetic interpretation of some antibiotics in camels. Arch. Inter. Pharmac. Chemoth. 216:186-195;1983.
21. 21. El Sheikh, H. A.; Ali, B. H.; Homeida, A, M.; Hapke, H. J. Pharmacokinetics of antipyrine and sulphadimidine in camels, sheep and goats. J. Vet. Pharmacol. Ther. 14:269-275; 1991.
22. 22. Etizon, Z.; Yagil, R. Renal function in camels following rapid rehydration. Physiol. Zoo. 59:558-562;1986.
23. 23. Fink-Gremmels, J.; Van Miert, A. S. J. P. A. M. Veterinary drugs: disposition, biotransformation and risk evaluation. Analyst 119:2521-2527;1994.
24. 24. Gavrielli, R.; Yagil, R.; Zir, G.; Creveld, C. V.; Glickman, A. Effect of water deprivation on the disposition kinetics of enrofloxacin in camels. J. Vet. Pharmacol. Ther. 18:333-339; 1995.
25. 25. Gyselynck, A.; Forrey, A.; Cutler, R. Pharmacokinetics of gentamicin distribution and plasma and renal clearance. J. Infect. Dis. 124:570-576;1971.
26. 26. Jaussaud, P.; Courtot, D. Caracteres analytiques, pharmacoinetiques et metaboliques du piroxicam: application an controle antidoppage chez le cheval. Rev. Med. Vet. 139:936-940;1988.
27. 27. Kadir, A.; Ali, B. H.; Al Hadrami, G.; Bashir, A. K.; Landoni, F.M.; Lees, P. Phenylbutazone pharmacokinetics and bioavailability in the dromedary camel (Camelus dromedarius). J. Vet. Pharmacol. Ther. In press;1997.
28. 28. Kaufman, C. F.; Bergman, E. N. Renal function studies in normal and toxaemic pregnant sheep. Cornell Vet. 68:124-137; 1978.
29. 29. Kinabo, L. D.; Bogan, J. A. Pharmacokinetic and histopathological investigations of isometamidium in cattle. Res. Vet. Sci. 44:267-269;1988.
30. 30. Kinabo, L. D.; McKellar, Q. A.; Eckersall, P. D. Isometamidium in pigs: disposition kinetics, tissue residues and adverse reactions. Res. Vet. Sci. 5:6-13;1991.
31. 31. Lees, P.; Taylor, J. B.; Higgins, A. J.; Sharma, S. C. Pharmacokinetics of phenylbutazone in the horse. J. Vet. Pharmacol. Ther. 9:204-212;1986.
32. 32. Mirgani, T. Fatty acid composition of hump triglycerides of the camel (Camelus dromedarius.) Comp. Biochem. Physiol. 58(B):211-213;1977.
33. 33. Nouws, J. F. M.; Vree, T. B.; Baakman, M.; Driessens, F.; Breukink, H. J.; Mevius, A. Age and dosage dependency in the plasma disposition and renal clearance of sulfamethazine and its N-acetyl and hydroxy metabolites in calves and cows. Am. J. Vet. Res. 47:642-649;1986.
34. 34. Obatomi, D. K.; Plummer, D. T. Influence of hydration states on the acute nephrotoxic effect of gentamicin in the rat. Toxicology 80:141-152;1993.
35. 35. Osbaldiston, G. W.; Moore, W. E. Renal function tests in cattle. J. Am. Vet. Assoc. 159:292-301;1971.
36. 36. Oukessou, M. Kinetic disposition of flunixin meglumine in the camel. Vet. Res. 25:71-75;1994.
37. 37. Oukessou, M.; Hossani, J.; Zine-Filali, R.; Toutain, P. L. Comparative benzyl pencillin pharmacokinetics in the dromedary, Camelus dromedarius, and in sheep. J. Vet. Pharmacol. Ther. 13:298-303:1990.
38. 38. Oukessou, M.; Toutain, P. L.; Galtier, P;. Alvinerie, M. Etude pharmacocinetique comparee du triclahendazole chez le mouton et le dromadaire. Rev. Elev. Med. Vet. Pays. Trop. 44: 447-452;1991.
39. 39. Oukessou, M.; Zine-Filali, R. A comparative study of phenylbutazone kinetics in the dromedary camel and sheep. 1st International Conference on Camel Research. Dubai, 420-421; 1992.
40. 40. Oukessou, M.; Zine-Filali, R.; Van Gool, F.; Alvinerie, M. (Ketoprofen pharmacokinetics in camel (Camelus dromedarius). Ind. Vet. J. 72:233-236;1995.
41. 41. Oukessou, M.; Ucelli-Thomas, V.; Toutain, P. L. Pharmacokinetics and local tolerance of a long-acting oxytetracycline formulation in camels. Am. J. Vet. Res. 53:1658-1662;1992.
42. 42. Raza, H.; Montague, W. Drug and xenobiotic metabolizing enzymes in camel liver: Multiple forms and species specific expression. Comp. Biochem. Physiol. 104C:137-145; 1993.
43. 43. Saint-Martin, G. V.; Nitcheman, M. F.; Richard, D.; Richard, M. A. Bibliographie sur Le Dromedane at Le Chameau. Maisons Alfort: Institutd' Elevage et de Medicin Veterinaire des Pays Tropicany 1990:824.
44. 44. Samman, A. Mohammed, A.; Saleh, A. A.; Sheth, K. The karyotype of the Arabian camel, Camelus dromedarius. J. King Saud. Univ. (SCI) 9:57-64;1993.
45. 45. Schroter, R. C.; Robertshaw, D.; Filali, R. Z. Brain cooling and respiratory heat exchange in camels during rest and exercise. Respir. Physiol. 78:95-105;1989.
46. 2 production. J. Vet. Pharmacol. Ther. 15:292-300; 1992.
47. 47. Vesell, E. S. The antipyrine test in clinical pharmacology: conceptions and misconceptions. Clin. Pharmacol. Ther. 26: 275-286;1979.
48. 48. Wardeh, M. F. The camel applied research and development network. J. Arid Environment, 26:105-111; 1994.
49. 49. Wasfi, I. A; Abdel Hadi, A. A.; Amiri, M. H.; Gadir, F. A.; Bashir, A. K. Pharmacokinetics and dose-regimen of Kanamycin in camels. J. Facult. Sci. U.A.E. 5:84-90;1993.
50. 50. Wash, I. A.; Abdel Hadi, A. A.; Amiri, M. H.; Gadir, F. A.; Bashir, A. K. Pharmacokinetics of gentamicin in the camel. Proc. 1st Inter. Camel Conf. Dubai, 393-396;1992.
51. 51. Wernery, U; Kaden, O. R. Infectious diseases of camelids. Berlin; Blackwell Wisenschafts-Verlag, 1995.
52. 52. Wilson. Towards committed collaborative camelid research. J. Arid Environ. 26:95-103;1994.
53. 53. Yagil, R. The desert camel-comparative physiological adaptation. Basel Kargen Ltd., 1985.
54. 54. Yagil, R. Renal function and water metabolism in the dromedary. Contrib. Nephrol. 102:161-170;1989.
55. 55. Yagil, R.; Berlyne, G. M. Glucose loading and dehydration in the camel. J. Appl. Physiol. 42:690-693;1977.
56. 56. Yagil, R.; Van Creveld C.; Ben-Zvi, Z.; Glickman, A.; Ziv, G. Disposition kinetics of chloramphenicol in normal and dehydrated camels. Proc. 6th EAVPT Congress; Edinburgh. 62; 1994a.
57. 57. Yagil, R.; Van Creveld, C.; Yaaran, A.; Glickman, A.; Ziv, G. Disposition kinetics of oxytetracycline in normal and dehydrated camels. Proc. 6th EAVPT Congress; Edinburgh. 101; 1994b.
58. 58. Younan, W.; Nouws, J. F. M.; Homedia, A. M.; Vree, T. B.; Degen, M. Pharmacokinetics and metabolism of sulphadimidine in the camel. J. Vet. Pharmacol. Ther. 12:327-329; 1989.
59. 59. Ziv, G.; Ben-Zvi, Z.; Yagil, R.; Van Creveld, C.; Glickman, A. Disposition kinetics of gentamicin in the normal and dehydrated camel. Proc. 5th EAVPT Congress. Copenhagen. 110-112;1992.
60. 60. Ziv, G.; Ben-Zvi, Z.; Yagil, R.; Creveld, C. V.; Glickman, A. Disposition kinetics of gentamicin in the normal and dehydrated camel. Acta Vet. Scand. 87:110-113;1991.
61. 61. Ziv, G.; Van Creveld, C.; Ben-Zvi, Z.; Glickman, A.; Yagil, R. Disposition kinetics of tylosin tartrate administered intravenously and intramusculatly to normal and water-deprived camels. J. Vet. Pharmacol. Ther. 18:299-305;1995.