Characterization of [3H]apafant binding to PAF receptor on rabbit platelet membranes: A comparison of a microplate filtration system and a standard method

Journal of Pharmacological and Toxicological Methods

Volumn 36, Issue 1, 1996, Pages 53-62

  Balsa, Dolors ^a   Merlos, Manuel ^a   Giral, Marta ^a   Ferrando, Rosa ^a   García Rafanell, Julián ^a   Forn, Javier ^a  

^a Grupo Uriach   (Spain)

Author keywords

Microplate Filtration System; PAF; PAF receptor binding; Rabbit platelet membranes; 3H Apafant

Indexed keywords

1 ACETYL 4 (8 CHLORO 5,6 DIHYDRO 11H BENZO[5,6]CYCLOHEPTA[1,2 B]PYRIDIN 11 YLIDENE)PIPERIDINE; APAFANT; FOROPAFANT; GINKGOLIDE B; LEXIPAFANT; LEXIPANT; N METHYL N [4 [2 METHYL 1H IMIDAZO[4,5 C]PYRIDIN 1 YLMETHYL]PHENYLSULFONYL]LEUCINE ETHYL ESTER; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR DERIVATIVE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG; UR 12670; ANTITHROMBOCYTIC AGENT; AZEPINE DERIVATIVE; CELL SURFACE RECEPTOR; FIBRINOGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; THROMBOCYTE ACTIVATING FACTOR; TRIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; IN VITRO STUDY; INTERMETHOD COMPARISON; MALE; MICROFILTRATION; NONHUMAN; RABBIT; TECHNIQUE; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE; ANIMAL; BINDING COMPETITION; COMPARATIVE STUDY; DRUG EFFECT; FILTRATION; METABOLISM; THROMBOCYTE;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

ANIMALS; AZEPINES; BINDING, COMPETITIVE; BLOOD PLATELETS; FILTRATION; MALE; PLATELET ACTIVATING FACTOR; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; RABBITS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; TRIAZOLES;

EID: 0030222488     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/1056-8719(96)00074-3     Document Type: Article

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