Nematode FMRFamide-related peptide (FaRP)-systems: Occurrence, distribution and physiology

International Journal for Parasitology

Volumn 26, Issue 8-9, 1996, Pages 927-936

  Maule, A G ^a,b   Geary, T G ^a   Marks, N J ^b   Bowman, J W ^a   Friedman, A R ^a   Thompson, D P ^a  

^a PFIZER INC   (United States)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

FMRFamide related peptides; nematodes; nervous system; neuromuscular function; neuropeptides

Indexed keywords

ANTHELMINTIC AGENT; NEUROPEPTIDE; NEUROPEPTIDE RECEPTOR; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE;

ANTHELMINTIC ACTIVITY; CATTLE; CONFERENCE PAPER; DRUG RESEARCH; NEMATODIASIS; NERVOUS SYSTEM; NONHUMAN; PHYSIOLOGY; VETERINARY MEDICINE;

BOS TAURUS; NEMATODA; VERMES; VERTEBRATA;

EID: 0030221738     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(96)80066-X     Document Type: Conference Paper

References (50)

1. Atkinson H. J., Isaac R. E., Harris P. D. & Sharpe C. M. 1988. FMRFamide-immunoreactivity within the nervous system of the nematodes Panagrellus redivivus, Caenorhabdidtis elegans and Heterodera glycines. Journal of Zoology London 216: 663-671.
2. Bascal Z. A., Montgomery A., Holden-Dye L., Williams R. G., Thorndyke M. C., Walker R. J., 1995. Histochemical mapping of NADPH diaphorase in the nervous system of the parasitic nematode, Ascaris suum. Parasitology 110: 625-637.
3. Bowman J. W., Geary T. G. & Thompson D. P. 1990. Electrophysiological characterization of the effects of nematode FMRFamide-like neuropeptides on Ascaris suum muscle cells. Neurotox '90 Abstracts: 129.
4. Bowman J. W., Friedman A. R., Thompson D. P., Ichhpurani A. K., Kellman M. F. & Geary T. G. 1996. Structure-activity relationships in a nematode FMRFamide-like peptide, KNEFIRFamide. Peptides 17: 381-387 .
5. Bowman J. W., Winterrowd C. A., Friedman A. R., Thompson D. P., Klein R. D., Davis J. P., Maule A. G. & Geary T. G. 1995. Nitric oxide mediates the inhibitory effects of SDPNFLRFamide, a nematode FMRFamide-like neuropeptide, in Ascaris suum. Journal of Neurophysiology 74: 1880-1888.
6. Brownlee D. J. A., Fairweather I. & Johnston C. F. 1993a. Immunocytochemical demonstration of neuropeptides in the peripheral nervous system of the roundworm Ascaris suum (Nematoda, Ascaroidea). Parasitology Research 79: 302-308.
7. Brownlee D. J. A., Fairweather I., Johnston C. F. & Shaw C. 1994a. Immunocytochemical demonstration of peptidergic and serotoninergic components in the enteric nervous system of the roundworm, Ascaris suum (Nematoda, Ascaroidea). Parasitology 108: 89-103.
8. Brownlee D. J. A., Brennan G. P., Halton D. W., Fairweather I. & Shaw C. 1994b. Ultrastructural localisation of pancreatic polypeptide-and FMRFamide-immunoreactivities within the central nervous system of the nematode, Ascaris suum (Nematoda, Ascaroidea). Parasitology 108: 587-593.
9. Brownlee D. J. A., Fairweather I., Johnston C. F., Smart D., Shaw C. & Halton D. W. 1993b. Immunocytochemical demonstration of neuropeptides in the central nervous system of the roundworm, Ascaris suum (Nematoda, Ascaroidea). Parasitology 106: 305-316.
10. Cowden C. & Stretton A. O. W. 1993. AF2, an Ascaris neuropeptide: isolation, sequence and bioactivity. Peptides 14: 423-430.
11. Cowden C. & Stretton A. O. W. 1995. Eight novel FMRFamide-like neuropeptides isolated from the nematode Ascaris suum. Peptides 163: 491-500.
12. Cowden C., Stretton A. O. W. & Davis A. E. 1989. AF1, a sequenced bioactive neuropeptide isolated from the nematode Ascaris suum. Neuron 2: 1465-1473.
13. Cowden C., Sithigorngul P., Brackley P., Guastella J. & Stretton A. O. W. 1993. Localisation and differential expression of FMRFamide immunoreactivity in the nematode Ascaris suum. Journal of Comparative Neurology 333: 455-468.
14. Davenport T. R. B., Lee D. L. & Isaac R. E. 1988. Immunocytochemical demonstration of a neuropeptide in Ascaris suum (Nematoda) using an anti-serum to FMRFamide. Parasitology 97: 81-88.
15. Franks C. J., Holden-Dye L., Williams R. G., Pang F. Y. & Walker R. J. 1994. A nematode FMRFamide-like peptide SDPNFLRFamide (PF1) relaxes the dorsal muscle strip preparation of Ascaris suum. Parasitology 108: 229-236.
16. Geary T. G., Klein R. D., Vanover L., Bowman J. W. & Thompson D. P. 1992a. The nervous system of helminths as targets for drugs. Journal of Parasitology 78: 215-230.
17. Geary T. G., Price D. A., Bowman J. W., Winterrowd C. A., Mackenzie C. D., Garrison R. D., Williams J. F. & Friedman A. R. 1992b. Two FMRFamide-like peptides from the free-living nematode Panagrellus redivivus. Peptides 13: 209-214.
18. Geary T. G., Bowman J. W., Friedman A. R., Maule A. G., Davis J. P., Winterrowd C. A., Klein R. D. & Thompson D. P. 1995. The pharmacology of FMRFamide-related neuropeptides in nematodes: new opportunities for rational anthelmintic discovery? International Journal for Parasitology 25: 1273-1280.
19. Halton D. W., Shaw C., Maule A. G. & Smart D. 1994. Regulatory peptides in helminth parasites. Advances in Parasitology 34: 164-227.
20. Holden-Dye L., Franks C. J., Williams R. G. & Walker R. J. 1995. The effect of the nematode peptides SDPNFLRFamide (PF1) and SADPNFLRFamide (PF2) on synaptic transmission in the parasitic nematode Ascaris suum. Parasitology 110: 449-455.
21. Jagdale G. B. & Gordon R. 1994. Distribution of FMRFamide-like peptide in the nervous system of a mermithid nematode, Romanomermis culicivorax. Parasitology Research 80: 467-473.
22. Johnston R. N., Shaw C., Halton D. W., Verhaert P. & Baguna J. 1995. GYIRFamide - a novel FMRFamide-related peptide (FaRP) from the triclad turbellarian, Dugesia tigrina. Biochemical and Biophysical Research Communications 2092: 689-697.
23. Keating C., Thorndyke M. C., Holden-Dye L., Williams R. G. & Walker R. J. 1994. The isolation of a FMRFamide-like peptide from the nematode Haemonchus contortus. Brain Research Association Abstracts 11: 16.11.
24. Kerboeuf D. & Dubois M. P. 1981. Mise en évidence chez un nematode parasite de vertébrés (Heligmosomoides polygyrus=Nematospiroides dubius Baylis, 1926) de cellules révélées en immunofluorescence par un anticorps anti a-endorphine. Comptes rendus de l'Academie des sciences, Paris 293: 675-678.
25. Leach L., Trudgill D. L. & Gahan P. B. 1987. Immunocytochemical localisation of neurosecretory amines and peptides in the free-living nematode, Goodeyus ulmi. Histochemical Journal 19: 471-475.
26. Li C. & Chalfie M. 1986. FMRFamide-like immunoreactivity in C. elegans. Society for Neuroscience Abstracts 12: 246.
27. Marks N. J., Shaw C., Davis J. P., Maule A. G., Halton D. W., Verhaert P., Geary T. G. & Thompson D. P. 1996. Isolation of AF2 (KHEYLRFamide) from Caenorhabditis elegans: evidence for the presence of more than one FMRFamide-related peptide encoding gene. Biochemical and Biophysical Research Communications. 217: 845-851.
28. Martin R. J., Sitamze J. M., Duittoz A. H. & Wermuth C. G. 1995. Novel arylaminopyridazine-GABA receptor antagonists examined electrophysiologically in Ascaris suum. European Journal of Pharmacology 267: 9-19.
29. Maule A. G., Halton D. W. & Shaw C. 1995a. Neuropeptide F: a ubiquitous invertebrate neuromediator? Hydrobiologia 305: 295-301.
30. Maule A. G., Shaw C., Halton D. W. & Thim L. 1993. GNFFRFamide: a novel FMRFamide-immunoreactive peptide isolated from the sheep tapeworm, Moniezia expansa. Biochemical and Biophysical Research Communications 1933: 1054-1060.
31. Maule A. G., Shaw C., Halton D. W., Curry W. J. & Thim L. 1994a. RYIRFamide: a turbellarian FMRFamide-related peptide (FaRP). Regulatory Peptides 50: 37-43.
32. Maule A. G., Shaw C., Bowman J. W., Halton D. W., Thompson D. P., Geary T. G. & Thim L. 1994b. KSAYMRFamide: a novel FMRFamide-related heptapeptide from the free-living nematode, Panagrellus redivivus, which is myoactive in the parasitic nematode, Ascaris suum. Biochemical and Biophysical Research Communications 2002: 973-980.
33. Maule A. G., Shaw C., Bowman J. W., Halton D. W., Thompson D. P., Geary T. G. & Thim L. 1994c. The FMRFamide-like neuropeptide AF2 (Ascaris suum) is present in the free-living nematode, Panagrellus redivivus (Nematoda, Rhabditida). Parasitology 109: 351-356.
34. Maule A. G., Geary T. G., Bowman J. W., Marks N. J., Blair K. L., Halton D. W., Shaw C. & Thompson D. P. 1995c. Inhibitory effects of nematode FMRFamide-related peptides (FaRPs) on muscle-strips from Ascaris suum. Invertebrate Neuroscience 1: 255-265.
35. Maule A. G., Shaw C., Bowman J. W., Halton D. W., Thompson D. P., Thim L., Kubiak T. M., Martin R. A. & Geary T. G. 1995b. Isolation and preliminary biological characterization of KPNFIRFamide, a novel FMRFamide-related peptide from the free-living nematode, Panagrellus redivivus. Peptides 161: 87-93.
36. McIntyre S. L. & Horvitz H. R. 1985. Immunochemical reactivity of neurons in wild type and mutant C. elegans to antisera against GABA, serotonin and CCK. Neuroscience Abstracts 11: 920.
37. Pang F. Y., Mason J., Holden-Dye L., Franks C. J., Williams R. G. & Walker R. J. 1995. The effects of the nematode peptide, KHEYLRFamide (AF2), on the somatic musculature of the parasitic nematode Ascaris suum. Parasitology 110: 353-362.
38. Price D. A. & Greenberg M. J. 1977. Structure of a molluscan cardioexcitatory neuropeptide. Science 197: 670-671.
39. Rosoff M. L., Burglin T. R. & Li C. 1992. Alternatively spliced transcripts of the flp-1 gene encode distinct FMRFamide-like peptides in Caenorhabditis elegans. Journal of Neuroscience 12: 2356-2361.
40. Rosoff M. L., Doble K. E., Price D. A. & Li C. 1993. The flp-1 propeptide is processed into multiple, highly similar FMRFamide-like peptides in Caenorhabditis elegans. Peptides 14: 331-338.
41. Santama N., Benjamin P. R. & Burke J. F. 1995. Alternative RNA splicing generates diversity of neuropeptide expression in the brain of the snail Lymnaea: in situ analysis of mutually exclusive transcripts of the FMRFamide gene. European Journal of Neuroscience 7: 65-76.
42. Schinkmann K. & Li C. 1992. Localization of FMRFamide-like peptides in Caenorhabditis elegans. Journal of Comparative Neurology 316: 251-260.
43. 2)-like peptides. Molecular Brain Research 24: 238-246.
44. Sithigorngul P., Stretton A. O. W. & Cowden C. & 1990. Neuropeptide diversity in Ascaris: an immunocytochemical study. Journal of Comparative Neurology 294: 362-376.
45. Smart D., Shaw C., Johnston C. F., Halton D. W., Fairweather I. & Buchanan K. D. 1992. Chromatographic and immunological characterisation of immunoreactivity towards pancreatic polypeptide and neuropeptide Y in the nematode Ascaris suum. Comparative Biochemistry and Physiology 102C: 477-481.
46. Stretton A. O. W., Cowden C., Sithigorngul P. & Davis R. E. 1991. Neuropeptides in the nematode Ascaris suum. Parasitology 102: S107-S116.
47. Stretton A. O. W., Davis R. E., Angstadt J. D., Donmoyer J. E. & Johnston C. D. 1985. Neural control of behaviour in Ascaris. Trends in Neuroscience 8: 294-300.
48. Walker R. J. 1992. Neuroactive peptides with an RFamide or Famide carboxyl terminus. Comparative Biochemistry and Physiology 102C: 213-222.
49. Warbrick E. V., Rees H. H. & Howells R. E. 1992. Immunocytochemical localisation of a FMRFamide-like peptide in the filarial nematodes Dirofilaria immitis and Brugia pahangi. Parasitology Research 78: 252-256.
50. Wikgren M. C. & Fagerholm H. P. 1993. Neuropeptides in sensory structures of nematodes. Acta Biologia Hungarica 44: 133-136.