The muddle with MAG

Molecular and Cellular Neurosciences

Volumn 8, Issue 2-3, 1996, Pages 84-92

  Filbin, Marie T ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN ASSOCIATED GLYCOPROTEIN;

GROWTH REGULATION; NERVE FIBER REGENERATION; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; WHITE MATTER;

EID: 0030221513     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1996.0047     Document Type: Review

References (56)

1. Bandtlow, C. E., Zachleder, T., and Schwab, M. E. (1990). Oligodendrocytes arrest neurite growth by contact inhibition. J. Neurosci. 10: 3837-3848.
2. Bandtlow, C. E., Schmidt, M. F., Hassinger, T. D., Schwab, M. E., and Kater, S. B. (1993). Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones. Science 259: 80-83.
3. Bartsch, U., Kirchhoff, F., and Schachner, M. (1989). Immunohistological localization of the adhesion molecules L1, N-CAM, and MAG in the developing and adult optic nerve of mice. J. Comp. Neurol. 284: 451-462.
4. Bartsch, L., Bandtlow, C. E., Schnell, L., Bartsch, S., Spillmann, A. A., Rubin, B. P., Hillenbrand, R., Montag, D., Schwab, M. E., and Schachner, M. (1995). Lack of evidence that the myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS. Neuron 15: 1375-1381.
5. Bedi, K. S., Winter, J., Berry, M., and Cohen, J. (1992). Adult rat dorsal root ganglion neurons extend neurites on predegenerated but not on normal peripheral nerves in vitro. Eur. J. Neurosci. 4: 193-200.
6. Bregman, B. S., Kunke-Bagden, E., Schnell, L., Dal, H. N., Gao, D., and Schwab, M. E. (1995). Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378: 498-501.
7. Brown, M. C., Perry, V. H., Lunn, E. R., Gordon, S., and Heumann, R. (1991). Macrophage dependence of peripheral sensory nerve regeneration: Possible involvement of nerve growth. Neuron 6: 359-370.
8. Brown, M. C., Lunn, E. R., and Perry, V. H. (1992). Consequences of slow Wallerian degeneration for regenerating motor and sensory axons. J. Neurobiol. 23: 521-536.
9. Carbonetto, S., Evans, D., and Cochart, P. (1987). Nerve fiber growth in culture in tissue substrates from central and peripheral nervous system. J. Neurosci. 7: 610-620.
10. Caroni, P., and Schwab, M. E. (1988a). Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron 1: 85-96.
11. Caroni, P., and Schwab, M. E. (1988b). Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading. J. Cell Biol. 106: 1281-1288.
12. Cheng, H., Cao, Y., and Olson, L. (1996). Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function. Science 273: 510-513.
13. Cole, J. S., Messing, A., Trojanowski, J. Q., and Lee, V. (1994). Modulation of axon diameter and neurofilament by hypomyelinating Schwann cells in transgenic mice. J. Neurosci. 14: 6956-6966.
14. Colello, R. J., and Schwab, M. E. (1994). A role for oligodendrocytes in the stabilization of optic axon numbers. J. Neurosci. 14: 6446-6452.
15. David, S., Braun, P. E., Jackson, D. L., Kottis, V., and McKerracher, L. (1995). Laminin overrides the inhibitory effects of peripheral nervous system and central nervous system myelin-derived inhibitors of neurite outgrowth. J. Neurosci. Res. 42: 594-602.
16. DeBellard, M. E., Tang, S., Mukhopadhyay, G., Shen, Y., and Filbin, M. T. (1996a). Myelin-associated glycoprotein inhibits axonal regeneration from a variety of neurons via interaction with a sialoglycoprotein. Mol. Cell. Neurosci. 7: 89-101.
17. DeBellard, M. E., Tang, T., Roder, J., and Filbin, M. T. (1996b). Inhibition of axonal regeneration by myelin involves a neuronal sialoglycoprotein. Soc. Neurosci. Abstr. 130.5.
18. Fawcett, J. W., and Keynes, R. J. (1990). Peripheral nerve regeneration. Annu. Rev. Neurosci. 13: 43-60.
19. Filbin, M. T. (1995). Myelin-associated glycoprotein: A role in myelination and in the inhibition of axonal regeneration? Curr. Opin. Neurobiol. 5: 588-595.
20. Filbin, M. T., Mukhopadhyay, G., Tang, S., DeBellard, M. E., and Shen, Y. (1996). Myelin-associated glycoprotein (MAG) as an inhibitor of axonal regeneration in both the PNS and the CNS. Peripheral Nerve (Japan) 7: 11-27.
21. Fruttiger, M., Montag, D., Schachner, M., and Martini, R. (1995). Crucial role for the myelin-associated glycoprotein in the maintenance of axonal-myelin integrity. Eur. J. Neurosci. 7: 511-515.
22. Johnson, P. W., Abramow-Newerly, W., Seilheimer, B., Sadoul, R., Tropak, M. B., Arquint, M., Dunn, R. J., Schachner, M., and Roder, J. C. (1989). Recombinant myelin associated glycoprotein confers neural adhesion and neurite outgrowth function. Neuron 3: 377-385.
23. Johnson, A. R. (1993). Contact inhibition in the failure of mammalian CNS axonal regeneration. BioEssays 15: 807-813.
24. Kapfhammer, J. P., and Schwab, M. E. (1994). Inverse patterns of myelination and GAP-43 expression in the adult CNS: Neurite growth inhibitors as regulators of neuronal plasticity? J. Comp. Neurol. 340: 194-206.
25. Kelm, S., Pelz, A., Schauer, R., Filbin, M. T., Tang, S., de Bellard, M.-E., Schnaar, R. L., Mahoney, J. A., Hartnell, A., Bradfield, P., and Crocker, P. R. (1994) Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily. Curr. Biol. 4: 965-972.
26. Keynes, R. J., and Cook, G. M. W. (1995). Repulsive and inhibitory signals. Curr. Opin. Neurobiol. 5: 75-82.
27. Kirkpatrick, L. L., and Brady, S. T. (1994). Modulation of axonal cytoskeleton by myelinating Schwann cells. J. Neurosci. 14: 7440-7450.
28. Lai, C., Brow, M. A., Nave, K. A., Noronha, A. B., Quarles, R. H., Bloom, F. E., Milner, R. J., and Sutcliffe, J. C. (1987). Two forms of 1B236/myelin-associated glycoprotein (MAG), a cell adhesion molecule for postnatal neural development, are produced by alternative splicing. Proc. Natl. Acad. Sci. USA 84: 4337-4341.
29. Li, C., Tropak, M. B., Gerlai, R., Clapoff, S., Abramow-Newerly, W., Trapp, B., Peterson, A., and Roder, J. (1994). Myelination in the absence of myelin-associated glycoprotein. Nature 369: 747-750.
30. Li, M., Shibata, A., Li, C., Braun, P. E., McKerracher, L., Roder, J., Kater, S. B., and David, S. (1996). Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse. J. Neurosci. Res., in press.
31. Luo, Y., Raible, D., and Raper, J. A. (1993). Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75: 217-227.
32. Luo, Y., and Raper, J. A. (1994). Inhibitory factors controlling growth cone motility and guidance. Curr. Opin. Neurobiol. 4: 648-654.
33. Martini, R., and Schachner, M. (1986). Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J. Cell Biol. 103: 2439-2448.
34. McKerracher, L., David, S., Jackson, D. L., Kottis, V., Dunn, R. J., and Braun, P. E. (1994). Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite outgrowth. Neuron 13: 805-811.
35. Messersmith, E. K., Leonardo, E. D., Shatz, C. J., Tessier-Lavigne, M., Goodman, C., and Kolodkin, A. L. (1995). Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord. Neuron 14: 949-959.
36. Montag, D., Giese, K. P., Bartsch, U., Martini, R., Lang, Y., Bluthmann, H., Karthigasan, J., Kirschner, D. A., Wintergerst, E. S., Nave, K. A., Zielasek, J., Toyka, K., Lipp, H. P., and Schachner, M. (1994). Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin. Neuron 13: 229-246.
37. Mukhopadhyay G., Doherty, P., Walsh, F. S., Crocker, P. R., and Filbin, M. T. (1994). A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13: 757-767.
38. Owens, G. C., and Bunge, R. P. (1991). Schwann cells infected with a recombinant retrovirus expressing myelin-associated glycoprotein antisense RNA do not form myelin. Neuron 7: 565-575.
39. Owens, G. C., Boyd, C. J., Bunge, R. P., and Salzer, J. L. (1990) Expression of recombinant myelin-associated glycoprotein in primary Schwann cells promotes the initial investment of axons by myelinating Schwann cells. J. Cell Biol. 111: 1171-1182.
40. Puschel, A. W., Adams, R. H., and Betz, H. (1995). Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron 14: 941-948.
41. Quarles, R. H. (1984). Myelin-associated glycoprotein in development and disease. Dev. Neurosci. 6: 285-303.
42. Salzer, J. L., Holmes, W. P., and Colman, D. R. (1987). The amino acid sequences of the myelin-associated glycoproteins: Homology to the immunoglobulin gene superfamily. J. Cell Biol. 104: 957-865.
43. Salzer, J. L., Pedraza, L., Brown, M., Struyk, A., Afar, D., and Bell, J. (1990). Structure and function of the myelin-associated glycoproteins. Ann. N. Y. Acad. Sci. 605: 29-43.
44. Sandrock, A. W., and Matthew, W. D. (1987). Identification of peripheral nerve neurite-outgrowth promoting activity by development and use of an in vitro bioassay. Proc. Natl Acad. Sci. USA 84: 6934-6938.
45. Savio, T., and Schwab, M. E. (1989). Rat CNS white matter, but not gray matter, is non-permissive for neuronal cell adhesion and fiber outgrowth. J. Neurosci. 9: 1126-1133.
46. Schafer, M., Fruttiger, M., Montag, D., Schachner, M., and Martini, R. (1996). Disruption of the gene for the myelin-associated glycoprotein improves axonal regrowth in C57BL/Wld mice. Neuron 16: 1107-1113.
47. Schnell, L., and Schwab, M. E. (1990). Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343: 269-272.
48. Schnell, L., Schneider, R., Kolbeck, R., Barde, Y.-A., and Schwab, M. E. (1994). Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367: 170-173.
49. Schwab, M. E., and Caroni, P. (1988). Oligodendrocytes and CNS myelin are non-permissive substrates for neurite outgrowth and fibroblast spreading in vitro. J. Neurosci. 8: 2381-2391.
50. Schwab, M. E., Kapfhammer, J. P., and Bandtlow, C. E. (1993). Inhibitors of neurite growth. Annu. Rev. Neurosci. 16: 565-596.
51. Schwegler, G., Schwab, M. E., and Kapfhammer, J. P. (1995). Increased collateral sprouting of primary afferents in the myelin-free spinal cord. J. Neurosci. 15: 2756-2767.
52. Shen, Y., Walsh, F. S., and Filbin, M. T. (1996). MAG expressed by Schwann cells inhibits axonal growth and branching. Soc. Neursci. Abstr. 130.6.
53. Tang, S., Shen, Y., DeBellard, M. E., Mukhopadhyay, G., Crocker, P., Doherty, P., and Filbin, M. T. (1996a). Only MAG of the sialoadhesins inhibits axonal regeneration. Soc. Neurosci. Abstr. 130.8.
54. Tang, S., Shen, Y., Mukhopadhyay, G., DeBellard, M. E., Crocker, P., and Filbin, M. T. (1996b). Sialic acid-recognition by myelin-associated glycoprotein (MAG) is at R118, which is necessary but insufficient to inhibit axonal regeneration. Submitted for publication.
55. Trapp, B. D. (1990). Myelin associated glycoprotein, location and potential function. Ann. N. Y. Acad. Sci. 605: 29-43.
56. Waegh, S. M. de, Lee, V. M.-Y., and Brady, S. T. (1992). Local modulation of neurofilament phosphorylation, axonal caliber and slow axonal transport by myelinating Schwann cells. Cell 68: 451-463.