Immunoautoradiographic and in situ hybridization analysis of corticotropin-releasing hormone biosynthesis in the hypothalamic paraventricular nucleus

Journal of Chemical Neuroanatomy

Volumn 11, Issue 1, 1996, Pages 49-56

  Herman, James P ^a   Morrison, David G ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Adrenalectomy; Hypothalamo pituitary adrenal (HPA) axis; Immunohistochemistry; mRNA; Neuropeptide; Translation

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; MESSENGER RNA;

ADRENALECTOMY; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HORMONE SYNTHESIS; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS NUCLEUS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMUNORADIOMETRIC ASSAY; IN SITU HYBRIDIZATION; MEDIAN EMINENCE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030200320     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-0618(96)00124-X     Document Type: Article

References (33)

1. Antoni, F.A. (1986) Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocrine Rev. 7, 351-378.
2. Berkenbosch, F., DeGoeij, D. and Tilders, F.J. (1989) Hypoglycemia enhances turnover of corticotropin-releasing factor and of vasopressin in the zona externa of the rat median eminence. Endocrinology 125, 28-34.
3. Berkenbosch, F. and Tilders, F.J. (1988) Effect of axonal transport blockade on corticotropin-releasing factor immunoreactivity in the median eminence of intact and adrenalectomized rats: relationship between depletion rate and secretory activity. Brain Res. 442, 312-320.
4. Blanchard, V., Raisman, V.R., Savasta, M., Hirsch, E., Javoy, A.F., Feuerstein, C. and Agid, Y. (1993) Cellular quantification of tyrosine hydroxylase in the rat brain by immunoautoradiography. J. Neurochem. 61, 617-626.
5. Bugnon, C., Fellmann, D. and Gouget, A. (1983) Changes in corticoliberin and vasopressin-like immunoreactivities in the zona externa of the median eminence in adrenalectomized rats. Immunocytochemical study. Neurosci. Lett. 37, 43-49.
6. de Goeij, D.C., Kvetnansky, R., Whitnall, M.H., Jezova, D., Berkenbosch, F. and Tilders, F.J. (1991) Repeated stress-induced activation of corticotropin-releasing factor neurons enhances vasopressin stores and colocalization with corticotropin-releasing factor in the median eminence of rats. Neuroendocrinology 53, 150-159.
7. Eberwine, J.H., Spencer, C., Newell, D. and Hoffman, A.R. (1993) mRNA structure, in situ, as assessed by microscopic techniques. Microsc. Res. Tech. 25, 19-28.
8. Fink, G., Robinson, I.C. and Tannahill, L.A. (1988) Effects of adrenalectomy and glucocorticoids on the peptides CRF-41, AVP and oxytocin in rat hypophysial portal blood. J. Physiol. (Lond.) 401, 329-345.
9. Healy, D.P. (1992) Radioimmunocytochemical localization of corticotropin-releasing factor and adrenocorticotropin in the hypothalamo-hypophyseal system of the rat: effects of adrenalectomy. J. Histochem. Cytochem. 40, 969-978.
10. Herman, J.P., Schafer, M.K.-H., Thompson, R.C. and Watson, S.J. (1992) Rapid regulation of CRH gene expression in vivo. Mol. Endocrinol. 6, 1061-1069.
11. Herman, J.P., Wiegand, S.J. and Watson, S.J. (1990) Regulation of basal corticotropin-releasing hormone and arginine vasopressin messenger ribonucleic acid expression in the para ventricular nucleus: effects of selective hypothalamic deafferentations. Endocrinology 127, 2408-2417.
12. Imaki, T., Nahan, J.L., Rivier, C., Sawchenko, P.E. and Vale, W. (1991) Differential regulation of corticotropin-releasing factor mRNA in rat brain regions by glucocorticoids and stress. J. Neurosci. 11, 585-599.
13. Ixart, G., Siaud, P., Mekaouche, M., Barbanel, G., Givalois, L., and Assenmacher, I. (1994) Short-term but not long-term adrenalectomy modulates amplitude and frequency of the CRH41 episodic release in push-pull cannulated median eminence of free-moving rats. Brain Res. 658, 185-191.
14. Kovacs, K. and Sawchenko, P.E. (1996) Sequence of stress-induced alterations in indices of synaptic transcriptional activation in parvocellular neurosecretory neurons. J. Neurosci. 16, 262-273.
15. Munro, H. (1993) The ferritin genes: their response to iron status. Nutr. Rev. 51, 65-73.
16. Olschowka, J.A., O'Donohue, T.L., Mueller, G.P. and Jacobowitz, D.M. (1982a) The distribution of corticotropin releasing factor-like immunoreactive neurons in rat brain. Peptides 3, 995-1015.
17. Olschowka, J.A., O'Donohue, T.L., Mueller, G.P. and Jacobowitz, D.M. (1982b) Hypothalamic and extrahypothalamic distribution of CRF-like immunoreactive neurons in the rat brain. Neuroendocrinology 35, 305-308.
18. Plotsky, P.M., Cunningham, E.T., Jr. and Widmaier, E.P. (1989) Catecholaminergic modulation of corticotropin-releasing factor and adrenocorticotropin secretion. Endocr. Rev. 10, 437-458.
19. Plotsky, P.M., Otto, S. and Sapolsky, R.M. (1986) Inhibition of immunoreactive corticotropin-releasing factor secretion into the hypophysial-portal circulation by delayed glucocorticoid feedback. Endocrinology 119, 1126-1130.
20. Plotsky, P.M. and Sawchenko, P.E. (1987) Hypophysial-portal plasma levels, median eminence content, and immunohistochemical staining of corticotropin-releasing factor, arginine vasopressin, and oxytocin after pharmacological adrenalectomy. Endocrinology 120, 1361-1369.
21. Raisman, V.R., Hirsch, E., Javoy, A.F., Vassort, C., Savasta, M., Feuerstein, C., Thibault, J. and Agid, Y. (1991) Quantitative autoradiography of tyrosine hydroxylase immunoreactivity in the rat brain. J. Neurochem. 57, 1212-1222.
22. Sawchenko, P.E. (1987a) Adrenalectomy-induced enhancement of CRF and vasopressin immunoreactivity in parvocellular neurosecretory neurons: anatomic, peptide, and steroid specificity. J. Neurosci. 7, 1093-1106.
23. Sawchenko, P.E. (1987b) Evidence for differential regulation of corticotropin-releasing factor and vasopressin immunoreactivities in parvocellular neurosecretory and autonomic-related projections of the paraventricular nucleus. Brain Res. 437, 253-263.
24. Sawchenko, P.E., Arias, C.A. and Mortrud, M.T. (1993) Local tetrodotoxin blocks chronic stress effects on corticotropin-releasing factor and vasopressin messenger ribonucleic acids in hypophysiotropic neurons. J. Neuroendocrinol. 5, 341-348.
25. Schafer, M.K.-H., Herman, J.P. and Watson, S.J. (1989) In situ hybridization analysis of gene expression in the HPA stress axis: Regulation by glucocorticoids. In: D. Ottoson and W. Rostene (Eds.), Visualization of Brain Function, pp. 11-22. The Macmillan Press, London.
26. Schipper, J., Werkman, T.R. and Tilders, F.J. (1984) Quantitative immunocytochemistry of corticotropin-releasing factor (CRF). Studies on nonbiological models and on hypothalamic tissues of rats after hypophysectomy, adrenalectomy and dexamethasone treatment. Brain Res. 293, 111-118.
27. Suda, T., Tomori, N., Tozawa, F., Mouri, T., Demura, H. and Shizume, K. (1983) Effects of bilateral adrenalectomy on immunoreactive corticotropin-releasing factor in the rat median eminence and intermediate-posterior pituitary. Endocrinology 113, 1182-1184.
28. Swanson, L.W. and Sawchenko, P.E. (1983) Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Ann. Rev. Neurosci. 6, 269-324.
29. Swanson, L.W. and Simmons, D.M. (1989) Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat. J. Comp. Neurol. 285, 413-435.
30. Whitnall, M.H. (1989) Stress selectively activates the vasopressin-containing subset of corticotropin-releasing hormone neurons. Neuroendocrinology 50, 702-707.
31. Whitnall, M.H. (1993) Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system. Prog. Neurobiol. 40, 573-629.
32. Whitnall, M.H., Key, S. and Gainer, H. (1987) Vasopressin-containing and vasopressin-deficient subpopulations of corticotropin-releasing factor axons are differentially affected by adrenalectomy. Endocrinology 120, 2180-2182.
33. Young, W.S., III, Mezey, E. and Siegel, R.E. (1986) Quantitative in situ hybridization histochemistry reveals increased levels of corticotropin-releasing factor mRNA after adrenalectomy in rats. Neurosci. Lett. 70, 198-203.