DNA Vaccines for Emerging Infectious Diseases: What If?

Emerging Infectious Diseases

Volumn 2, Issue 3, 1996, Pages 168-175

  Whalen, Robert G ^a,b,c,d,e  

^a CNRS   (France)

^b Centre de Recherche Interdisciplinaire en Biologie   (France)

^c Fr Natl Ctr for Sci Research

^d INSTITUT PASTEUR   (France)

^e OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE;

ANIMAL; COMMUNICABLE DISEASE; DISEASE MODEL; HUMAN; IMMUNOLOGY; INFECTION CONTROL; RESEARCH; REVIEW;

ANIMALS; COMMUNICABLE DISEASE CONTROL; COMMUNICABLE DISEASES; DISEASE MODELS, ANIMAL; HUMANS; RESEARCH; VACCINES, DNA;

EID: 0030184352     PISSN: 10806040     EISSN: None     Source Type: Journal    
DOI: 10.3201/eid0203.960302     Document Type: Review

References (53)

1. Culliton BJ. The greatest threat of all. Nature Medicine 1995;1:1221.
2. Moran N. World Health Organization plans rapid deployment. Nature Medicine 1995;1:1234.
3. Whalen RG, Davis HL. DNA-mediated immunization and the energetic immune response to hepatitis B surface antigen. Clin Immunol Immunopathol 1995;75:1-12.
4. Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A, et al. Direct gene transfer into mouse muscle in vivo. Science 1990;247:1465-8.
5. Fynan EF, Webster RG, Fuller DH. et al. DNA vaccines: protective immunizations by parental, mucosal, and gene-gun inoculations. Proc Natl Acad Sci USA 1993; 90:11478-82.
6. Muraskin W. The war against hepatitis B: a history of the international task force on hepatitis B immunization. Philadelphia; University of Pennsylvania Press, 1995.
7. Cox GJ, Zamb TJ, Babiuk LA. Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA. J Virol 1993;67:5664-7.
8. Davis HL, Michel M-L, Whalen RG. DNA-based immunization for hepatitis B induces continuous secretion of antigen and high levels of circulating antibody. Human Molecular Genetics 1993;2:1847-51.
9. Davis HL, Michel M-L, Mancini M, Schleef M, Whalen RG. Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen. Vaccine 1994;12:1503-9.
10. Davis HL, Schirmbeck R, Reimann J, Whalen RG. DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to hepatitis B surface antigen. Human Gene Therapy 1995;6:1447-56.
11. Major ME, Vitvitski L, Mink MA, Schleef M, Whalen RG, Trepo C, et al. DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid. J Virol 1995; 69:5798-805.
12. Michel M-L, Davis HL, Schleef M, Mancini M, Tiollais P, Whalen RG. DNA-mediated immunization to the hepatitis B surface antigen in mice: Aspects of the humoral response mimic hepatitis B viral infection in humans. Proc Natl Acad Sci USA 1995;92:5307-11.
13. Schirmbeck R, Bohm W, Ando E, Chisari FV, Reimann J. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice. J Virol 1995;69:5929-34.
14. Davis HL, Mancini M, Michel M-L, Whalen RG. DNA-mediated immunization to hepatitis B surface antigen: longevity of primary response and effect of boost. Vaccine 1996 in press.
15. Lagging LM, Meyer K, Hoft D, Houghton M, Belshe RB, Ray R. Immune responses to plasmid DNA encoding the hepatitis C virus core protein. J Virol 1995;69:5859-63.
16. Rouse RJ, Nair SK, Lydy SL, Bowen JC, Rouse BT. Induction in vitro of primary cytotoxic T-lymphocyte responses with DNA encoding herpes simplex virus proteins. J Virol 1994;68:5685-9.
17. Ghiasi H, Cai S, Slanina S, Nesburn AB, Wechsler SL. Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge. Antiviral Research 1995;28:147-57.
18. Manickan E, Rouse RJ, Yu Z, Wire WS, Rouse BT. Genetic immunization against herpes simplex virus. Protection is mediated by CD4+ T lymphocytes. J Immunol 1995; 155:259-65.
19. Wang B, Boyer J, Srikantan V, Coney L, Carrano R, Phan C, et al. DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates. DNA Cell Biol 1993;12:799-805.
20. Wang B, Ugen KE, Srikantan V, Agadjanyan MG, Dang K, Refaeli Y, et al. Gene inoculation generates immune responses against human immunodeficiency virus type I. Proc Natl Acad Sci USA 1993;90:4156-60.
21. Lu S, Santoro JC, Fuller DH, Haynes JR, Robinson HL. Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice. Virology 1995;209:147-54.
22. Wang B, Boyer J, Srikantan V, Ugen K, Gilbert L, Phan C, et al. Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation. Virology 1995;211:102-12.
23. Fynan EF, Robinson HL, Webster RG. Use of DNA encoding influenza hemagglutinin as an avian influenza vaccine. DNA Cell Biol 1993;12:785-9.
24. Montgomery DL, Shiver JW, Leander KR, Perry HC, Friedman A, Martinez D, et al. Heterologous and homologous protection against influenza A by DNA vaccination: Optimization of DNA vectors. DNA Cell Biol 1993; 12:777-83.
25. Robinson HL, Hunt LA, Webster RG. Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 1993;11:957-60.
26. Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Feigner PL, Dwarki VJ, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993;259:1745-9.
27. Yankauckas MA, Morrow JE, Parker SE, Abai A, Rhodes GH, Dwarki VJ, et al. Long-term anti-nucleoprotein cellular and humoral immunity is induced by intramuscular injection of plasmid DNA containing NP gene. DNA Cell Biol 1993;12:771-6.
28. Raz E, Carson DA, Parker SE, Parr TB, Abai AM, Aichinger G, et al. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc Natl Acad Sci USA 1994;91:9519-23.
29. Donnelly JJ, Friedman A, Martinez D, Montgomery DL, Shiver JW, Motzel SL, et al. Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus. Nature Medicine 1995;1:583-7.
30. Martins LP, Lau LL, Asano MS, Ahmed R. DNA vaccination against persistent viral infection. J Virol 1995;69:2574-82.
31. Yokoyama M, Zhang J, Whitton JL. DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection. J Virol 1995;6964:2684-8.
32. Zarozinski CC, Fynan EF, Selin LK, Robinson HL, Welsh RM. Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein. J Immunol 1995;154:4010-7.
33. Lowrie DB, Tascon RE, Colston MJ, Silva CL. Towards a DNA vaccine against tuberculosis. Vaccine 1994; 12:1537-40.
34. Barry MA, Lai WC, Johnston SA. Protection against mycoplasma infection using expression-library immunization. Nature 1995;377:632-5.
35. Lai WC, Bennett M, Johnston SA, Barry MA, Pakes SP. Protection against Mycoplasma pulmonis infection by genetic vaccination. DNA Cell Biol 1995;14:643-51.
36. Hoffman SL, Sedegah M, Hedstrom RC. Protection against malaria by immunization with a Plasmodium yoelii circumsporozoite protein nucleic acid vaccine. Vaccine 1994;12:1529-33.
37. Sedegah M, Hedstrom R, Hobart P, Hoffman SL. Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. Proc Natl Acad Sci USA 1994;91:9866-70.
38. Mor G, Klinman DM, Shapiro S, Hagiwara E, Sedegah M, Norman JA, et al. Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA. J Immunol 1995;155:2039-46.
39. Xiang ZQ, Spitalnik S, Tran M, Wunner WH, Cheng J, Ertl HC. Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus. Virology 1994;199:132-40.
40. Xiang Z, Ertl HCJ. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 1995;2:129-35.
41. Xiang ZQ, Spitalnik SL, Cheng J, Erikson J, Wojczyk B, Ertl HC. Immune responses to nucleic acid vaccines to rabies virus. Virology 1995;209:569-79.
42. Yang W, Waine GJ, McManus DP. Antibodies to Schistosoma japonicum (Asian bloodfluke) paramyosin induced by nucleic acid vaccination. Biochem Biophys Res Commun 1995;212:1029-39.
43. Davis HL, Demeneix BA, Quantin B, Coulombe J, Whalen RG. Plasmid DNA is superior to viral vectors for direct gene transfer in adult mouse skeletal muscle. Human Gene Therapy 1993;4:733-40.
44. Whalen RG. DNA vaccines, Cyberspace and self-help programs. Intervirology, 1996 (in press).
45. Davis HL, Whalen RG, Demeneix BA. Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression. Human Gene Therapy 1993;4:151-9.
46. Eisenbraun MD, Fuller DH, Haynes JR. Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization. DNA Cell Biol 1993;12:791-7.
47. Dixon B. The third vaccine revolution. Bio/Technology 1995;13:420.
48. Kuhober A, Pudollek H-P, Reifenberg K, Chisari FV, Schlicht H-J, Reimann J, et al. DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice. J Immunol 1996;156:3687-95.
49. Yasutomi Y, Robinson HL, Lu S, Mustafa F, Lekutis C, Arthos J, et al. Simian immunodeficiency virus-specific cytotoxic T-lymphocyte induction through DNA vaccination of rhesus monkeys. J Virol 1996;70:678-81.
50. Xu D, Liew FY. Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein of L. major. Immunology 1995;84:173-6.
51. Donnelly JJ, Martinez D, Jansen KU, Ellis RW, Montgomery DL, Liu MA. Protection against papillomavirus with a polynucleotide vaccine. J Infect Dis 1996;173:314-20.
52. Hsu C-H, Chua K-Y, Tao M-H, Lai Y-L, Wu H-D, Huang S-K, et al. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nature Med 1996;2:540-4.
53. Prince AM, Whalen RG, Brotman B. Successful nucleic acid based immunization of newborn chimpanzees against HBV. Vaccine, 1996 (in press).