메뉴 건너뛰기




Volumn 2, Issue 5, 1996, Pages 371-382

Molecular biology and biochemistry of human recombinant follicle stimulating hormone (Puregon®)

Author keywords

FSH; Heterologous gene expression; Isohormones; Peptide mapping; Recombinant glycoprotein hormone

Indexed keywords

FOLLITROPIN; RECOMBINANT PROTEIN;

EID: 0030132712     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/2.5.371     Document Type: Article
Times cited : (153)

References (46)
  • 1
    • 0345713270 scopus 로고
    • Structure and function of the gonadotrophin free alpha molecule of pregnancy
    • Lustbader, J.W., Puett, D. and Ruddon, R.W. (eds), Springer Verlag, New York
    • Blithe, D.L. (1994) Structure and function of the gonadotrophin free alpha molecule of pregnancy. In Lustbader, J.W., Puett, D. and Ruddon, R.W. (eds), Glycoprotein Hormones. Springer Verlag, New York, pp. 156-166.
    • (1994) Glycoprotein Hormones , pp. 156-166
    • Blithe, D.L.1
  • 2
    • 0021952192 scopus 로고
    • Heterogeneity of rat FSH by chromatofocusing: Studies on serum FSH, hormone released in vitro and metabolic clearance rates of its various forms
    • Blum, W.F.P. and Gupta, D. (1985) Heterogeneity of rat FSH by chromatofocusing: studies on serum FSH, hormone released in vitro and metabolic clearance rates of its various forms. J. Endocrinol., 105, 29-37.
    • (1985) J. Endocrinol. , vol.105 , pp. 29-37
    • Blum, W.F.P.1    Gupta, D.2
  • 3
    • 0003125825 scopus 로고
    • Recombinant follicle stimulating hormone. II. Biochemical and biological characteristics
    • Krommelin D.J.A. and Schellekens H. (eds), Kluwer Academic Publishers, Dordrecht
    • de Boer, W. and Mannaerts, B. (1990) Recombinant follicle stimulating hormone. II. Biochemical and biological characteristics. In Krommelin D.J.A. and Schellekens H. (eds), From Clone to Clinics, Developments in Biotherapy. Vol. 1. Kluwer Academic Publishers, Dordrecht, pp. 253-259.
    • (1990) From Clone to Clinics, Developments in Biotherapy , vol.1 , pp. 253-259
    • De Boer, W.1    Mannaerts, B.2
  • 4
    • 0026589475 scopus 로고
    • Expression of recombinant human FSH, LH, and CG in mammalian cells: A structure-function model for therapeutic drug design
    • Boime, I., Keene, J., Galway A.B., Fares, F.M. et al. (1992) Expression of recombinant human FSH, LH, and CG in mammalian cells: a structure-function model for therapeutic drug design. Sem. Reprod. Endocrinol., 10, 45-50.
    • (1992) Sem. Reprod. Endocrinol. , vol.10 , pp. 45-50
    • Boime, I.1    Keene, J.2    Galway, A.B.3    Fares, F.M.4
  • 5
    • 0020473793 scopus 로고
    • Human chorionic gonadotrophin beta-subunit is encoded by at least eight genes arranged in tandem and inverted pairs
    • Boorstein, W.R., Vamvakopoulos, N.C. and Fiddes, J.C. (1982) Human chorionic gonadotrophin beta-subunit is encoded by at least eight genes arranged in tandem and inverted pairs. Nature, 300, 419-422.
    • (1982) Nature , vol.300 , pp. 419-422
    • Boorstein, W.R.1    Vamvakopoulos, N.C.2    Fiddes, J.C.3
  • 6
    • 0027177562 scopus 로고
    • Recombinant human thyroid stimulating hormone: Development of a biotechnology product for detection of metastatic lesions of thyroid carcinoma
    • Cole E.S., Lee, K., Lauziere, K. et al. (1993) Recombinant human thyroid stimulating hormone: development of a biotechnology product for detection of metastatic lesions of thyroid carcinoma. Biotechnology, 11, 1014-1024.
    • (1993) Biotechnology , vol.11 , pp. 1014-1024
    • Cole, E.S.1    Lee, K.2    Lauziere, K.3
  • 7
    • 0025119324 scopus 로고
    • High-performance tryptic mapping of recombinant bovine somatotropin
    • Dougherty, J.J., Snyder, L.M., Sinclair, R.L. and Robins, R.H. (1990) High-performance tryptic mapping of recombinant bovine somatotropin. Anal. Biochem., 190, 7-20.
    • (1990) Anal. Biochem. , vol.190 , pp. 7-20
    • Dougherty, J.J.1    Snyder, L.M.2    Sinclair, R.L.3    Robins, R.H.4
  • 8
    • 0028225468 scopus 로고
    • The quality control of biotechnology products
    • Federici, M.M. (1994) The quality control of biotechnology products. Biologicals, 22, 151-159.
    • (1994) Biologicals , vol.22 , pp. 151-159
    • Federici, M.M.1
  • 9
    • 0018667990 scopus 로고
    • Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotrophin
    • Fiddes, J.C. and Goodman, H.M. (1979) Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotrophin. Nature, 281, 351-356.
    • (1979) Nature , vol.281 , pp. 351-356
    • Fiddes, J.C.1    Goodman, H.M.2
  • 10
    • 0019166519 scopus 로고
    • The cDNA for the beta-subunit of human chorionic gonadotrophin suggests evolution of a gene by readthrough into the 3′-untranslated region
    • Fiddes, J.C. Goodman, H.M. (1980) The cDNA for the beta-subunit of human chorionic gonadotrophin suggests evolution of a gene by readthrough into the 3′-untranslated region. Nature, 286, 684-687.
    • (1980) Nature , vol.286 , pp. 684-687
    • Fiddes, J.C.1    Goodman, H.M.2
  • 11
    • 0019831147 scopus 로고
    • The gene encoding the common alpha subunit of the four human glycoprotein hormones
    • Fiddes, J.C. and Goodman, H.M. J. (1981) The gene encoding the common alpha subunit of the four human glycoprotein hormones. J. Mol. Appl. Genet., 1, 3-18.
    • (1981) J. Mol. Appl. Genet. , vol.1 , pp. 3-18
    • Fiddes, J.C.1    Goodman, H.M.J.2
  • 12
    • 0024270948 scopus 로고
    • The role of quality control in biotechnology: An analytical perspective
    • Garnick, R.L., Solli, N.J. and Papa, P.A. (1988) The role of quality control in biotechnology: an analytical perspective. Anal. Chem., 60, 2546-2557.
    • (1988) Anal. Chem. , vol.60 , pp. 2546-2557
    • Garnick, R.L.1    Solli, N.J.2    Papa, P.A.3
  • 13
    • 14744295978 scopus 로고
    • Characterizing recombinant proteins
    • Geisow, M.J. (1991) Characterizing recombinant proteins. Biotechnology, 9, 921-924.
    • (1991) Biotechnology , vol.9 , pp. 921-924
    • Geisow, M.J.1
  • 14
    • 0020463609 scopus 로고
    • Alpha subunit of rat pituitary glycoprotein hormones. Primary structure of the precursor determined from the nucleotide sequence of cloned cDNA's
    • Godine, J.E., Chin, W.W. and Habener, J.F. (1982) Alpha subunit of rat pituitary glycoprotein hormones. Primary structure of the precursor determined from the nucleotide sequence of cloned cDNA's. J. Biol. Chem., 257, 8368-8371.
    • (1982) J. Biol. Chem. , vol.257 , pp. 8368-8371
    • Godine, J.E.1    Chin, W.W.2    Habener, J.F.3
  • 15
    • 0023928616 scopus 로고
    • Asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin
    • Green, E.D. and Baenzinger, J.U. (1988) Asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin. J. Biol. Chem., 263, 25-35.
    • (1988) J. Biol. Chem. , vol.263 , pp. 25-35
    • Green, E.D.1    Baenzinger, J.U.2
  • 16
    • 0020620001 scopus 로고
    • Cloning of cDNA encoding the pre-beta subunit of mouse thyrotropin
    • Gurr, J.A. Catterall, J.F. and Kouides, I.A. (1983) Cloning of cDNA encoding the pre-beta subunit of mouse thyrotropin. Proc. Natl. Acad. Sci. USA, 80, 2122-2126.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 2122-2126
    • Gurr, J.A.1    Catterall, J.F.2    Kouides, I.A.3
  • 17
    • 0025043857 scopus 로고
    • Isolation and structure determination of the intact sialylated N-linked carbohydrate chains of recombinant human follitropin expressed in Chinese hamster ovary cells
    • Hård, K. Mekking, A., Damm, J.B.L. et al. (1990) Isolation and structure determination of the intact sialylated N-linked carbohydrate chains of recombinant human follitropin expressed in Chinese hamster ovary cells. Eur. J. Biochem., 193, 263-271.
    • (1990) Eur. J. Biochem. , vol.193 , pp. 263-271
    • Hård, K.1    Mekking, A.2    Damm, J.B.L.3
  • 18
    • 0022178074 scopus 로고
    • Molecular cloning of the human thyrotropin-beta subunit gene
    • Hayashizaki, Y., Miyai, K., Kato, K. and Matsubara, K. (1985) Molecular cloning of the human thyrotropin-beta subunit gene. FEBS Lett., 188, 394-400.
    • (1985) FEBS Lett. , vol.188 , pp. 394-400
    • Hayashizaki, Y.1    Miyai, K.2    Kato, K.3    Matsubara, K.4
  • 19
    • 0025911417 scopus 로고
    • Chemical procedures for C-terminal sequencing of peptides and proteins
    • Inglis, A.S. (1991) Chemical procedures for C-terminal sequencing of peptides and proteins. Anal. Biochem., 195, 183-196.
    • (1991) Anal. Biochem. , vol.195 , pp. 183-196
    • Inglis, A.S.1
  • 20
    • 0020683104 scopus 로고
    • Role of carbohydrate in human chorionic gonadotrophin. Effect of deglycosylation on the subunit interaction and on its in vitro and in vivo biological properties
    • Kalyan, N.K. and Bahl, O.P. (1981) Role of carbohydrate in human chorionic gonadotrophin. Effect of deglycosylation on the subunit interaction and on its in vitro and in vivo biological properties. J. Biol. Chem., 258, 67-74.
    • (1981) J. Biol. Chem. , vol.258 , pp. 67-74
    • Kalyan, N.K.1    Bahl, O.P.2
  • 21
    • 0023287617 scopus 로고
    • The production of mammalian proteins in Saccharomyces cerevisiae
    • Kingsman, S.M., Kingsman, A.J. and Mellor, J. (1987) The production of mammalian proteins in Saccharomyces cerevisiae. Trends Biotechnol., 5, 53-57.
    • (1987) Trends Biotechnol. , vol.5 , pp. 53-57
    • Kingsman, S.M.1    Kingsman, A.J.2    Mellor, J.3
  • 22
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K., (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 23
    • 0029089434 scopus 로고
    • In-vitro biopotency and glycoform distribution of recombinant human follicle stimulating hormone (Org 32489), Metrodin and Metrodin-HP
    • Lambert, A., Rodgers, M., Mitchell, R. et al. (1995) In-vitro biopotency and glycoform distribution of recombinant human follicle stimulating hormone (Org 32489), Metrodin and Metrodin-HP. Hum. Reprod., 10, 1928-1935.
    • (1995) Hum. Reprod. , vol.10 , pp. 1928-1935
    • Lambert, A.1    Rodgers, M.2    Mitchell, R.3
  • 24
    • 0030132584 scopus 로고    scopus 로고
    • Structure-function relationship of recombinant FSH (Org 32489)
    • de Leeuw R., Mulders, J., Voortman, G. et al. (1996) Structure-function relationship of recombinant FSH (Org 32489). Mol. Hum. Reprod., 2, 361-369.
    • (1996) Mol. Hum. Reprod. , vol.2 , pp. 361-369
    • De Leeuw, R.1    Mulders, J.2    Voortman, G.3
  • 25
    • 0027672078 scopus 로고
    • Isolation and characterization of three recombinant human granulocyte colony stimulating factor His → Gln isoforms produced in Escherichia coli
    • Lu, H.S., Fausset, P.R., Sotos, L.S. et al. (1993) Isolation and characterization of three recombinant human granulocyte colony stimulating factor His → Gln isoforms produced in Escherichia coli. Protein Expression Purific., 4, 465-472.
    • (1993) Protein Expression Purific. , vol.4 , pp. 465-472
    • Lu, H.S.1    Fausset, P.R.2    Sotos, L.S.3
  • 26
    • 0025838783 scopus 로고
    • Comparative in vitro and in vivo studies on the biological characteristics of recombinant human follicle stimulating hormone
    • Mannaerts, B., de Leeuw, R., Geelen, J. et al. (1991) Comparative in vitro and in vivo studies on the biological characteristics of recombinant human follicle stimulating hormone. Endocrinology, 129, 2623-2630.
    • (1991) Endocrinology , vol.129 , pp. 2623-2630
    • Mannaerts, B.1    De Leeuw, R.2    Geelen, J.3
  • 27
    • 0022553618 scopus 로고
    • Transcriptional selectivity of viral genes in mammalian cells
    • McKnight, S. and Tjian, R. (1986) Transcriptional selectivity of viral genes in mammalian cells. Cell, 46, 795-805.
    • (1986) Cell , vol.46 , pp. 795-805
    • McKnight, S.1    Tjian, R.2
  • 28
    • 0010431097 scopus 로고
    • Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells
    • Ochi, A., Hawley, R.G., Hawley, T. et al. (1983) Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells. Proc. Natl. Acad. Sci. USA, 80, 6352-6355.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6352-6355
    • Ochi, A.1    Hawley, R.G.2    Hawley, T.3
  • 29
    • 0027369036 scopus 로고
    • The use of peptide mapping for the detection of heterogeneity in recombinant DNA-derived products
    • O'Connor (1993) The use of peptide mapping for the detection of heterogeneity in recombinant DNA-derived products. Biologicals, 21, 111-117.
    • (1993) Biologicals , vol.21 , pp. 111-117
    • O'Connor1
  • 30
    • 0016191288 scopus 로고
    • Human follicle stimulating hormone (hFSH). First proposal for the amino acid sequence of the alpha-subunit (hFSH-alpha) and first demonstration of its identity with the alpha-subunit of human luteinizing hormone (hLH.alpha)
    • Parlow, A.F. and Shome, B.J. (1974) Human follicle stimulating hormone (hFSH). First proposal for the amino acid sequence of the alpha-subunit (hFSH-alpha) and first demonstration of its identity with the alpha-subunit of human luteinizing hormone (hLH.alpha). Clin. Endocrinol. Metab., 39, 199-202.
    • (1974) Clin. Endocrinol. Metab. , vol.39 , pp. 199-202
    • Parlow, A.F.1    Shome, B.J.2
  • 31
    • 0019729482 scopus 로고
    • Glycoprotein hormones: Structure and function
    • Pierce, J.G. and Parsons, T.F. (1981) Glycoprotein hormones: structure and function. Ann. Rev. Biochem., 50, 465-495.
    • (1981) Ann. Rev. Biochem. , vol.50 , pp. 465-495
    • Pierce, J.G.1    Parsons, T.F.2
  • 32
    • 84873782420 scopus 로고
    • Genetics of somatic mammalian cells. III. Long term cultivation of euploid cells from human and animal subjects
    • Puck T.T. (1958) Genetics of somatic mammalian cells. III. Long term cultivation of euploid cells from human and animal subjects. J. Exp. Med., 108, 945.
    • (1958) J. Exp. Med. , vol.108 , pp. 945
    • Puck, T.T.1
  • 33
    • 0028691996 scopus 로고
    • Peptide mapping of recombinant proteins
    • Brown, F. and Lubiniecki, A.S. (eds), Karger, Basel
    • Rohde, M.F., Lu, H.S. and Rush, R.S. (1994) Peptide mapping of recombinant proteins. In Brown, F. and Lubiniecki, A.S. (eds), Genetic Stability and Recombinant Product Consistency. Karger, Basel, pp. 121-127.
    • (1994) Genetic Stability and Recombinant Product Consistency , pp. 121-127
    • Rohde, M.F.1    Lu, H.S.2    Rush, R.S.3
  • 34
    • 0002711923 scopus 로고
    • Gonadotropic hormones: Relationship between structure and function with emphasis on antagonists
    • Academic Press, New York
    • Sairam, M.R. (1983) Gonadotropic hormones: relationship between structure and function with emphasis on antagonists. Hormonal Proteins and Peptides X1, Academic Press, New York, pp. 1-79.
    • (1983) Hormonal Proteins and Peptides X1 , pp. 1-79
    • Sairam, M.R.1
  • 35
    • 0019488640 scopus 로고
    • Primary structure of the ovine pituitary follitropin beta-subunit
    • Sairam, M.R., Seidah, N.G. and Chretien, M. (1981) Primary structure of the ovine pituitary follitropin beta-subunit. Biochem. J., 197, 541-552.
    • (1981) Biochem. J. , vol.197 , pp. 541-552
    • Sairam, M.R.1    Seidah, N.G.2    Chretien, M.3
  • 36
    • 0017293833 scopus 로고
    • Amino acid sequence of the beta-subunit of follicle-stimulating hormone from human pituitary glands
    • Saxena B.B. and Rathman, P. J. (1976) Amino acid sequence of the beta-subunit of follicle-stimulating hormone from human pituitary glands. Biol. Chem., 251, 993-1005.
    • (1976) Biol. Chem. , vol.251 , pp. 993-1005
    • Saxena, B.B.1    Rathman, P.J.2
  • 37
    • 0023748278 scopus 로고
    • A re-evaluation of the amino acid sequence of human follitropin beta-subunit
    • Shome, B., Parlow, A.F., Liu, W.-K. et al. (1988) A re-evaluation of the amino acid sequence of human follitropin beta-subunit. J. Prot. Chem., 7, 325-339.
    • (1988) J. Prot. Chem. , vol.7 , pp. 325-339
    • Shome, B.1    Parlow, A.F.2    Liu, W.-K.3
  • 38
    • 0026485387 scopus 로고
    • Molecular structures of glycoprotein hormones and functions of their carbohydrate components
    • Stockell Hartree, A. and Renwick, A.G.C. (1992) Molecular structures of glycoprotein hormones and functions of their carbohydrate components. Biochem. J., 287, 665-679.
    • (1992) Biochem. J. , vol.287 , pp. 665-679
    • Stockell Hartree, A.1    Renwick, A.G.C.2
  • 39
    • 0021265260 scopus 로고
    • Evolution of the genes for the beta subunits of human chorionic gonadotrophin and luteinizing hormone
    • Talmadge, K., Vamvakopoulos N.C. and Fiddes, J.C. (1984) Evolution of the genes for the beta subunits of human chorionic gonadotrophin and luteinizing hormone. Nature, 307, 37-40.
    • (1984) Nature , vol.307 , pp. 37-40
    • Talmadge, K.1    Vamvakopoulos, N.C.2    Fiddes, J.C.3
  • 40
    • 0028890259 scopus 로고
    • Glycoprotein hormones: Glycobiology of gonadotrophins, thyrotrophin and free α subunit
    • Thotakura, N.R. and Blithe, D.L. (1995) Glycoprotein hormones: glycobiology of gonadotrophins, thyrotrophin and free α subunit. Glycobiology, 5, 3-10.
    • (1995) Glycobiology , vol.5 , pp. 3-10
    • Thotakura, N.R.1    Blithe, D.L.2
  • 41
    • 0023877706 scopus 로고
    • Immunological and biological potencies of the different molecular species of gonadotrophins
    • Ulloa-Aguirre, A., Espinoza, R., Damian-Matsumura, P. and Chappel S.C. (1988) Immunological and biological potencies of the different molecular species of gonadotrophins. Hum. Reprod., 3, 491-501.
    • (1988) Hum. Reprod. , vol.3 , pp. 491-501
    • Ulloa-Aguirre, A.1    Espinoza, R.2    Damian-Matsumura, P.3    Chappel, S.C.4
  • 42
    • 0028845654 scopus 로고
    • Follicle-stimulating isohormones: Characterization and physiological relevance
    • Ullua-Aguirre, A., Midgley, A.R., Beitins, I.Z. and Padmanabhan, V. (1995) Follicle-stimulating isohormones: characterization and physiological relevance. Endocrine Rev., 16, 765-787.
    • (1995) Endocrine Rev. , vol.16 , pp. 765-787
    • Ullua-Aguirre, A.1    Midgley, A.R.2    Beitins, I.Z.3    Padmanabhan, V.4
  • 43
    • 0019985965 scopus 로고
    • Synthesis and assembly of hepatitis B virus surface antigen particles in yeast
    • Valenzuela, P., Medina, A., Rutter, W.J. et al. (1982) Synthesis and assembly of hepatitis B virus surface antigen particles in yeast. Nature, 298, 347-350.
    • (1982) Nature , vol.298 , pp. 347-350
    • Valenzuela, P.1    Medina, A.2    Rutter, W.J.3
  • 44
    • 0001029672 scopus 로고
    • Recombinant Follicle Stimulating Hormone I. Construction, selection and characterization of a cell line
    • Crommelin, D.J.A. and Schellekens, H. (eds), Kluwer Academic Publishers, Dordrecht
    • Van Wezenbeek, P., Draaijer, J., van Meel, F. and Olijve, W. (1990) Recombinant Follicle Stimulating Hormone I. Construction, selection and characterization of a cell line. In Crommelin, D.J.A. and Schellekens, H. (eds), From Clone to Clinics, Developments in Biotherapy. Vol. 1. Kluwer Academic Publishers, Dordrecht, pp. 245-251.
    • (1990) From Clone to Clinics, Developments in Biotherapy , vol.1 , pp. 245-251
    • Van Wezenbeek, P.1    Draaijer, J.2    Van Meel, F.3    Olijve, W.4
  • 45
    • 0023931957 scopus 로고
    • Amplified expression constructs for human tissue-type plasminogen activator in Chinese hamster ovary cells: Instability in the absence of selective pressure
    • Weidle, U.H., Buckel, P. and Wienberg, J. (1988) Amplified expression constructs for human tissue-type plasminogen activator in Chinese hamster ovary cells: instability in the absence of selective pressure. Gene, 66, 193-203.
    • (1988) Gene , vol.66 , pp. 193-203
    • Weidle, U.H.1    Buckel, P.2    Wienberg, J.3
  • 46
    • 0346222463 scopus 로고
    • DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells
    • Wigler, M., Pellicer, A., Silverstein, S. et al. (1979) DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. Proc. Natl. Acad. Sci. USA, 76, 1373-1376.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 1373-1376
    • Wigler, M.1    Pellicer, A.2    Silverstein, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.