Induction of melanogenesis during the various melanoma growth phases and the role of tyrosinase, lysosome-associated membrane proteins, and p90 calnexin in the melanogenesis cascade

Journal of Investigative Dermatology Symposium Proceedings

Volumn 1, Issue 2, 1996, Pages 195-202

  Salopek, Thomas G ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM BINDING PROTEIN; CALNEXIN; LEUKOCYTE ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MELANIN; MEMBRANE PROTEIN; MONOPHENOL MONOOXYGENASE;

ANIMAL; BIOSYNTHESIS; CELL TRANSFORMATION; GLYCOSYLATION; HUMAN; MELANOMA; PATHOLOGY; PHYSIOLOGY; REVIEW;

ANIMALS; ANTIGENS, CD; CALCIUM-BINDING PROTEINS; CALNEXIN; CELL TRANSFORMATION, NEOPLASTIC; GLYCOSYLATION; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MELANINS; MELANOMA; MEMBRANE GLYCOPROTEINS; MONOPHENOL MONOOXYGENASE;

EID: 0030112276     PISSN: 10870024     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Aitken A: Active site motifs, phosphorylation, and other post-traiislational modification. In: Identification of Protein Consensus Sequences. Ellis Hoywood Publishers, West Sussex, England, 1990
2. Albelda SM: Biology of disease-Role of intcgrins and other cell adhesion molecules in tumor progression and metastasis. Lab Investigation 68:4-17, 1993
3. Amos B, Lotan R: Modulation of lysosomal-associated membrane glycoproteins during retinoic acid-induced embryonal carcinoma cell differentiation. J Biol Chem 265:19192-19198, 1990
4. Barrio-Canal JG, Bonifacino JS, Yuan L, Sandoval IV: Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins. J Biol Chem 261:16755-16763, 1990
5. Bhatnagar V, Anjaiah S, Puri N, Darshanam BNA, Ramaiah A: pH of melanosomes of B16 murine melanoma is acidic: its physiological importance in the regulation of melanin biosynthesis. Arch Biochem Biaphys 307:183-192, 1993
6. Blume-Jensen P, Claesson-Welsh L, Siegbahn A, Zsebo KM, Westermark B, Heldin C-H: Activation of human c-Kit product by ligand-induced dimerizadon mediates circular actin reorganization and chemotaxis. EMBOJ 10:4121-4128, 1991
7. Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A: The protooncogene (-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature (Land) 335:88-89, 1988
8. Coussens L, Van Beveren C, Smith D, Chen E, Mitchcll RL, Isacke CM, Verma IM, Ullrich A: Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus. Nature (Land) 320:277-280, 1986
9. Dakour J, Vinayagamoorthy M, Chen H, Luo D, Dixon W, Jimbow K: Identification of a cDNA for Ca+"""-binding calnexin-like phosphoprotein (p90) on melanosomes in normal and malignant human melanocytes. Exp Cell Res 209:288-300, 1993a
10. Dakour J, Jimbow K, Vinayagamoorthy T, Luo D, Chen H: Characterization of melanosome-associated proteins by establishment of monoclonal antibodies and immunoscreening of a melanoma cDNA library through an anti-melanosome antibody. Melanoma Res 3:331-336, 1993b
11. Der JE, Dixon WT, Jimbow K, Horikoshi T: A murine monoclonal antibody, MoAb HMSA-5, against a melanosomal component highly expressed in early stages, and common to normal and neoplastic melanocytes. BrJ Cancer 67:47-57, 1993
12. Elder DE, Clark WH, Elenitsas R, Guerry D, Halpern AC: The early and intermediate precursor lesions of tumor progression in the melanocytic system: common acquired nevi and atypical (dysplastic) nevi. Seminars in Diag Path 10:18-35, 1993
13. Fukuda M, Viitala J, Matteson J, Carlsson SR: Cloning of cDNAs encoding human lysosomal membrane glycoprotcins, h-lamp-1 and h-lamp-2. J Biol Client 263: 18920-18928, 1988
14. Funasaka Y, Boulton T, Cobb M, Yarden Y, Fan B, Lyman SD, Williams DE, Anderson DM, Zakut R, Mishima Y, Halaban R: c-Kit-Kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogenc-activated protein kinase but is down-regulated in melanomas. Mol Biol Cell 3:197-209, 1992
15. Galvin K, Krishna S, Ponchel F, Frolchlich M, Cummings DE, Carlson R, WandsJR, Issebacher KJ, Pillai S, Ozuturk M: The major histocompatibility complex class 1 antigen-binding protein p88 is the product of the calnexin gene. Proc Natl Acad Sri 89:8452-8456, 1989
16. Geissler EN, McFarland EC, Russell ES: Analysis of pleiotropism at the dominant white-spotting (O locus of the house mouse: a description often new Il'allcles. Genetics 97:237-361, 1981
17. Geissler EN, Ryan MA, Housman DE: The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene. Cell 55:185-192, 1988
18. Halldin MM, Cookjr WS, Kawashima T, Crutcher WA, Fukuyama K: Identification of 5-S-cysteinyldopa by high performance liquid chromatography in biopsies from patients with dysplastic melanocytic nevi. Cancer Res 47:636-638, 1987
19. Hara H, Lee MH, Chen H, Luo D, Jimbow K: Role of gene expression and protein synthesis of tyrosinase, TRP-1, LAMP-1 and CD63 in UVB-induced melanogenesis in human melanomas. J Invest Dermatol 102:495-500, 1994
20. Herlyn M, Graeven U, Speicher D. Sela BA, Bennicelli JL, Kath R, Guerry D IV:
21. Jackson MR, Cohen-Doyle MF, Petcrson PA, Williams DB: Regulation of MHC Class I Transport by the molecular chaperone, calnexin (p88, IP90). Science 263:384-387, 1994
22. Jimbow K, Fitzpatrick TB, Szabo G, Hori Y: Congenital circumscribed hypomelanosis: a characterization based on electron microscopic study of tuberous sclerosis, nevus pigmcntosus and piebaldism. J Invest Dcnnatol 64:50-62, 1975
23. Jimbow K, Horikoshi T, Takahashi H, Akutsu Y, Maeda K: Fine structural and immunohistochemical properties of dysplastic melanocytic nevi: comparison with malignant melanoma. J Invest Dcnnatol 92:3045-3095, 1989
24. Jimbow K, Fitzpatrick TB, Wick M: Biochemistry and physiology of melanin pigmentation. In: Goldsmith LA (ed.). Physiology and Molecular Biology of the Skin. Oxford University Press New York, 1991 pp 873-909
25. Jimbow K, Alena F, Dixon W, Hara H: Regulator)' factors of pheo- and eumelanogenesis in melanogenic compartments. Pigment Cell Res 2(suppl):36-42, 1992
26. Jimbow K, Lee SK, King MG, Hara H, Chen H, Dakour Jt Marusyk H: Melanin pigments and melanosomal proteins as differentiation markers unique to normal and neoplastic melanocytes.J Invest Dennatot 100:2595-2685, 1993a
27. Jimbow K, Iwashina T, Alcna F, Yamada K, Pankovich J, Umemura T: Exploitation of pigment biosynthesis pathway as a selective chemotherapeutic approach for malignant melanoma. J Invest Dcnnatol 100:2315-2385, 1993b
28. Jimbow K, Hara H, Vinayagamoorthy T, Luo D, Dakour J, Yamada K, Dixon W, Chcn H: Molecular control of melanogencsis in malignant melanoma: Functional assessment of tyrosinasc and Lamp gene families by UV exposure and gene co-transfection, and cloning of a cDNA encoding calnexin, a possible melanogenesis "chaperone." J Dcnnatol 21:894-906, 1994a
29. Jimbow K, Luo D, Chcn H, Hara H, Lee MH: Coordinated mRNA and protein expression of human Lamp-1 in induction of melanogenesîs after UV-B exposure and co-transfection of human tyrosinase and TRP-1 cDNAs. Pigment Cell Res 7:311-319, 1994b
30. Jimbow K, Reszka K, Schmilz S, Salopek T, Thomas P: Distribution of eu- and pheomelanins in human skin and melanocytic tumors, and their photoprotective and phototoxic properties. In: Zeise L, Chcdekel MR, Fitzpatrick TB (eds.). Melanin: Its Role in Human Photoprotection. Valdenmar Publishing Company, Overland Park, Kansas, 1995 pp 155-175
31. Kanemoto T, Reich R, Royce L, Greatorex D, Adler SH, Shiraishi N, Martin GR. Yamada Y, Kleinman HK: Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagcnase IV production. Proc Hatl Acad Sd USA 87:2279-2283, 1990
32. Kath R, Rodeck U, Menssen HD, Mancianti M-L, Linnenbach AJ, Elder DE, Herlyn M: Tumor Progression in the human melanocytic system. Anticancer Res 9:865-872, 1989
33. Lev S, Givol D, Yardcn Y: A specific combination of substrates is involved in signal transduction by the fciY-cncoded receptor. EMBOJ 10:647-654, 1991
34. Luo D, Chen H, Jimbow K: Co-transfcction of genes encoding human tyrosine and tyrosinase-relatcd protein-1 prevents melanocyte death and enhances melanin pigmentation and gene expression of Lamp-1. lïxp Cell Res 213:231-241, 1994
35. Luo D, Chen H, Searles, G, Jimbow K: Coordinated mRNA expression of C-Kit with tyrosinase and TRP-1 in melanin pigmentation of normal and malignant human melanocytes and transient activation of tyrosinasc by Kit/SCF-R. Melanoma Res (in press)
36. Morrcau H, Gajart NJ, Gillemans N, Willemsen R, Van der Horst GT, d'Azzo A: Alternative splicing of β-galactosidase mRNA generates the classic lysosomal enzyme and a β-galactosidase-related protein. J Bioehem 264:20655-20663, 1989
37. Natali PG, Nicotra MR, Winkler AB, Cavalière R, Bigotti A, Ullrich A: Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogenc receptor. IntJ Cancer 52:197-201, 1992
38. Ou W-J, Camcron PH, Thomas DY, Bcrgeron JJM: Association of folding intermediates of glycoprotcins with calnexin during protein maturation. Nature 364:771-776, 1993
39. Park H-Y, Russakovsky, V, Ohno S, Gilchrest BA: The β isoform of protein kinase C stimulates human melanogenesis by activating tyrosinase in pigment cells. J Biol Chem 268:11742-11749, 1993
40. Peters C, Braun M, Weber B, Wendland M, Schmidt B, Pohlmann R, Waheed A, Von Figura K: Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes. EMBO J 9:3497-3506, 1990
41. Peterson LL, Woodward WR, Fletcher WS, Palmquist M, Tucker MA, Ilias A: Plasma 5-S-cysteinyldopa differentiates patients with primary and metastatic melanoma from patients with dysplastic nevus syndrome and normal subjects. J Am Acad Dcnnatol 19:509-515, 1988
42. Reszka K, Jimbow K: Electron-donor and acceptor properties of melanin pigments in the skin. In: Fuchs J, Packer L (eds.). Oxtdatwe Stress in Dermatology. Marcel Dekker Inc, New York, 1993, pp 287-320
43. Russell ES: Hereditary anemias of the mouse: a review for geneticists. Aâv Genet 20:347-459, 1979
44. Salopek TG, Jinibow K: I mmunohis to chemical heterogeneity by melanosomal markers and S-100. AmJ Dermatopath 13:130-136, 1991
45. Salopek TG, Yamada K, Ito S, Jimbow K: Dysplastic melanocytic nevi contain high levels ofpheomelanin: quantitative comparison ofpheomelanîn/eumelanin levels between normal skin, common nevi and dysplastic nevi. Pigment Cell Res 4:172-179, 1991
46. Scarles GE, Dixon W, Thomas P, Jimbow K: Divalent cations control cell-substrate adhesion in normal and malignant human melanocytes. J Invest Dcnnatol (in press)
47. Shearman MS, Herbst R, Schlcssïnger J, Ullrich A: Phosphaudyllnositol 3'-kinase associates with pl45c"ku as part of a cell type characteristic multimcric signalling complex. EMBOJ 12:3817-3826, 1993
48. Silvers WK: The coat colors of mice: a model for gene action and interaction. Sp ringe r-Velag, New York, 1979, pp 206-241
49. Spritz RA, Holmes SA, Ramesar R, Greenbcrg J, Curtis D, Beighton P: Mutations of the KIT (mast/stem cell growth factor receptor) proto-oncogene account for a continuous range ofphenotypes in human piebaldism. Am J Hum Genet 51:1058-1065, 1992
50. Tsukamoto K, Jackson IJ, Urabe K, Montague PM, Hearing VJ: A second tyrsoinase-relatcd protein, TRP-2, is a niclanogenic enzyme termed DOPAchrome tau-tomerase. EMBOJ 11:519-526, 1992
51. Ullrich A, Schlessinger J: Signal transduction by receptors with tyrosinase kinase activity. Cell 61:203-212, 1990
52. Varani J, Mitra RS, McCIenic BJ, Fligiel SEG, Inman DR. Dixit VM, Nickoloff BJ: Modulation of tibronectin production in normal human melanocytes and malignant melanoma cells by interferon-y and tumor necrosis factor-a. Ain J Path 134:827-836, 1989
53. Vinayagamoorthy T, Dakour J, Dixon W, Jimbow K: cDNA-based functional domains of a calnexin-like melanosomal protein, p90. Melanoma Res 3:263-269, 1993
54. Wada I, Rindrcss D, Camcron PU, Ou W-J, Doherty JJ, Louvard D, Bell AW, Dignard D, Thomas DY, Bergeron JJM: SSRa and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane. J Biol Chem 266:19599-19610, 1991
55. Wada I, Ou W-J, Liu M-C, Scheele G: Chaperone function of calnexin for the folding intermediate of gpSO, the major secretory protein in MDCK cells. J Biol Chem 269:7464-7472, 1994
56. Witte ON: Steel locus defines new multipotent growth factor. Cell 63:5-6, 1990
57. Yarden Y, Escobedo JA, Kuang W-J, Yang-Feng TL, Daniel TO, Tremble PM, Chen EY, Ando ME, Harkins RN, Francke U, Fried VA, Ullrich A, Williams LT: Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature 323:226-232, 1986
58. Yoshida K, Oshima A, Shimmoto M, Fukuhara Y, Sakuraba H, Yanagisawa N, Suzuki Y: Human β-galactosidase gene mutations in GM,-gangliosidosis: a common mutation among Japanese adult/chronic cases. Am J Hum Genet 49:435-442, 1991
59. Zakut R, Perils R, Eliyahu S, Yarden Y, Givol D, Lyman SD, Halaban R: Kit ligant (mast cell growth factor) inhibits the growth of fcif-exprcssing melanoma cells. Oncogcne 8:2221-2229, 1993
60. Zscbo KM, Williams DA, Geissler EN, Broudy VC, Martin FH, Atkins HL, Hsu RY, Birkett NC, Okino KH, Murdock DC, Jacobsen FW, Langley KE, Smith KA, Takcishi T, Cattanach BM, Galli SJ, Suggs SV: Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 63:213-224, 1990