Selective hippocampal lesions differentially affect the phenotypic fate of transplanted neuronal precursor cells

Experimental Neurology

Volumn 139, Issue 1, 1996, Pages 61-72

  Shihabuddin, L S ^a   Holets, V R ^a,b   Whittemore, S R ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b Natl Tuberous Sclerosis Association   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KAINIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CELL STRUCTURE; CELL TRANSPLANTATION; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; NERVE CELL PLASTICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; STEM CELL;

EID: 0030012720     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1996.0081     Document Type: Article

References (59)

1. ANDERSON, D. J. 1989. The neural crest cell lineage problem: Neuropoiesis. Neuron 3: 1-12.
2. BAYER, S. 1980. Development of the hippocampal region in the rat. II. Morphogenesis during embryonic and early postnatal life. J. Comp. Neurol. 190: 115-134.
3. BJÖRKLUND, A., S. B. DUNNETT, U. STENEVI, M. E. LEWIS, AND S. D. IVERSEN. 1980. Reinnervation of the denervated striatum by substantia nigra transplants: Functional consequences as revealed by pharmacological and sensorimotor testing. Brain Res. 199: 303-333.
4. BJÖRKLUND, A., O. LINDVALL, O. ISACSON, P. BRUNDIN, K. WICTORIN, R. E. STRECKER, D. J. CLARKE, AND S. B. DUNNET. 1987. Mechanism of action of intracerebral neural implants: Studies on nigral and striatal grafts to the lesioned striatum. Trends Neurosci. 10: 509-516.
5. BJÖRKLUND, A., AND U. STENEVI. 1984. Intracerebral neural implants: Neural replacement and reconstruction of damaged circuitries. Annu. Rev. Neurosci. 7: 279-308.
6. BJÖRKLUND, A., U. STENEVI, R. H. SCHMIDT, S. B. DUNNETT, AND F. H. GAGE. 1983. Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cells implanted in different brain sites. Acta Physiol. Scand. Suppl. 522: 9-18.
7. CEPKO, C. L. 1989. Immortalization of neural cells via retrovirus-mediated oncogene transduction. Annu. Rev. Neurosci. 12: 47-65.
8. COTMAN, C. W., M. NIETO-SAMPEDRO, AND S. R. WHITTEMORE. 1985. Relationships between neurotrophic factors and transplant-host integration. Pages 169-178 in A. Björklund and U. Stenevi, Eds., Neural Grafting in the Mammalian CNS. Elsevier, Amsterdam.
9. DUSART, I., S. MARTY, AND M. PESCHANSKI. 1991. Glial changes following an excitotoxic lesion in the CNS. II. Astrocytes. Neuroscience 45: 541-549.
10. EMERICH, D. F., M. RAGOZZINE, M. N. LEHMAN, AND P. R. SANBERG. 1992. Behavioral effects of neural transplantation. Cell Transplant. 1: 401-427.
11. FIELD, P. M., P. J. SEELEY, M. FROTSCHER, AND G. RAISMAN. 1991. Selective innervation of embryonic hippocampal transplants by adult host dentate granule cell axons. Neuroscience 41: 713-727.
12. FISHER, L. J., AND F. H. GAGE. 1993. Grafting in the mammalian central n ervous system. Physiol. Rev. 73: 583-616.
13. FOSTER, G. A., M. SCHULTZBERG, F. H. GAGE, A. BJÖRKLUND, T. HÖKFELT, A. C. CUELLO, A. A. VERHOFSTAD, T. J. VISSER, AND P. C. EMSON. 1988. Transmitter expression and morphological development of embryonic medullary and mesencephalic raphe neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus. Exp. Brain Res. 70: 225-241.
14. FOSTER, G. A., M. SCHULTZBERG, F. H. GAGE, A. BJÖRKLUND, T. HÖKFELT, A. C. CUELLO, A. A. VERHOFSTAD, T. J. VISSER, AND P. C. EMSON. 1988. Transmitter expression and morphological development of embryonic medullary and mesencephalic raphe neurons after transplantation to the adult rat central nervous system. III. Grafts to the striatum. Exp. Brain Res. 70: 242-255.
15. FOSTER, G. A., M. SCHULTZBERG, F. H. GAGE, A. BJÖRKLUND, T. HOKFELT, H. NORNES, A. C. CUELLO, A. A. VERHOFSTAD, AND T. J. VISSER. 1985. Transmitter expression and morphological development of embryonic medullary and mesencephalic raphe neurones after transplantation to the adult rat central nervous system. I. Grafts to the spinal cord. Exp. Brain Res. 60: 427-444.
16. FROTSCHER, M., J. KRAFT, AND U. ZORN. 1988. Fine structure of identified neurons in the primate hippocampus: A combined Golgi/EM study in the baboon. J. Comp. Neurol. 275: 254-270.
17. GAGE, F. H., AND L. J. FISHER. 1991. Intracerebral grafting: A tool for the neurobiologist. Neuron 6: 1-12.
18. GAGE, F. H., J. RAY, AND L. J. FISHER. 1995. Isolation, characterization, and use of stem cells from the CNS. Annu. Rev. Neurosci. 18: 159-192.
19. GÄHWILAR, B. H. 1984. Development of the hippocampus in vitro: Cell types, synapses and receptors. Neuroscience 11: 751-760.
20. GAO, W.-Q., AND M. E. HATTEN. 1994. Immortalizing oncogenes subvert the establishment of granule cell identity in developing cerebellum. Development 120: 1059-1070.
21. GAO, W.-Q., N. HEINTZ, AND M. E. HATTEN. 1991. Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron 6: 705-715.
22. GAO, W.-Q., X.-L. LIU, AND M. E. HATTEN. 1992. The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation. Cell 68: 841-854.
23. GOLDSCHMIDT, R. B., AND O. STEWARD. 1982. Neurotoxic effects of colchicine: Differential susceptibility of CNS neuronal populations. Neuroscience 7: 695-714.
24. HERMAN, J. P., N. ABROUS, A. VIGNY, J. DULLUC, AND M. LEMOAL. 1988. Distorted development of intracerebral grafts: Long-term maintenance of tyrosine hydroxylase-containing neurons in grafts of cortical tissue. Dev. Brain Res. 40: 81-88.
25. KESSLAK, J. P., M. NIETO-SAMPEDRO, J. GLOBUS, AND C. W. COTMAN. 1986. Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation. Exp. Neurol. 92: 377-390.
26. KOSHINAGA, M., AND S. R. WHITTEMORE. 1995. The temporal and spatial activation of microglia in fiber tracts undergoing anterograde and retrograde degeneration following spinal cord injury. J. Neurotrauma 12: 209-222.
27. KROMER, L. F. 1985. Factors in neural transplants which influence regeneration in the mature mammalian central nervous system. Pages 309-318 in A. Björklund and U. Stenevi, Eds., Neural Grafting in the Mammalian CNS. Elsevier, New York.
28. LABANDEIRA-GARCIA, J. L., K. WICTORIN, J. R. CUNNINGHAM, AND A. BJÖRKLUND. 1991. Development of intrastriatal grafts and their afferent innervation from the host. Neuroscience 42: 407-426.
29. LINDVALL, O., AND A. BJÖRKLUND. 1989. Transplantation strategies in the treatment of Parkinson's disease: Experimental basis and clinical trials. Acta Neurol. Scand. 126: 197-210.
30. LINDVALL, O., P. BRUNDIN, H. WIDNER, S. REHNCRONA, B. GUSTAVI, R. FRACKOWIAK, K. L. LEENDERS, G. SAWLE, J. C. ROTHWELL, C. D. MARSDEN, AND A. BJÖRKLUND. 1990. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 247: 574-577.
31. MACKLIS, J. D. 1993. Transplanted neocortical neurons migrate selectively into regions of neuronal degeneration produced by chromophore-targeted laser photolysis. J. Neurosci. 13: 3848-3863.
32. MARTY, S., I. DUSART, AND M. PESCHANSKI. 1991. Glial changes following an excitotoxic lesion in the CNS. I. Microglia/ macrophages. Neuroscience 45: 529-539.
33. MCKAY, R. D. G. 1989. The origins of cellular diversity in the mammalian central nervous system. Cell 58: 815-821.
34. MITCHELL, J., L. E. SUNDSTROM, AND H. V. WHEAL. 1993. Microglial and astrocytic cell responses in the rat hippocampus after intracerebroventricular kainic acid injection. Exp. Neurol. 121: 224-230.
35. MUDRICK, L. A., AND K. G. BAIMBRIDGE. 1991. Hippocampal neurons transplanted into ischemically lesioned hippocampus: Anatomical assessment of survival, maturation and integration. Exp. Neurol. 86: 233-247.
36. MUDRICK, L. A., K. G. BAIMBRIDGE, AND M. J. PEET. 1989. Hippocampal neurons transplanted into ischemically lesioned hippocampus: Electroresponsiveness and reestablishment of circuitries. Exp. Brain Res. 76: 333-342.
37. NADLER, J. V., B. W. PERRY, AND C. W. COTMAN. 1978. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature 271: 676-677.
38. ONIFER, S. M., S. R. WHITTEMORE, AND V. R. HOLETS. 1993. Variable morphological differentiation of a raphe-derived neuronal cell line following transplantation into the adult rat CNS. Exp. Neurol. 122: 130-142.
39. PARK, J. K., T. H. JOH, AND F. F. EBNER. 1986. Tyrosine hydroxylase is expressed by neocortical neurons after transplantation. Proc. Natl. Acad. Sci. USA 83: 7495-7498.
40. RENFRANZ, P. J., M. G. CUNNINGHAM, AND R. D. G. MCKAY. 1991. Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain. Cell 66: 713-729.
41. ROBINSON, A. P., T. M. WHITE, AND D. W. MASON. 1986. Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MCR OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57: 239-247.
42. SHEEN, V. L., AND J. D. MACKLIS. 1995. Targeted neocortical cell death in adult mice guides migration and differentiation of transplanted embryonic neurons. J. Neurosci. 15: 8378-8392.
43. SHETTY, A. K., AND D. A. TURNER. 1995. Enhanced cell survival in fetal hippocampal suspension transplants grafted to adult rat hippocampus following kainate lesions: A 3-dimensional graft reconstruction study. Neuroscience 67: 561-582.
44. SHIHABUDDIN, L. S., J.-P. BRUNSCHWIG, V. R. HOLETS, M. B. BUNGE, AND S. R. WHITTEMORE. 1996. Induction of mature neuronal properties in immortalized precursor cells following transplantation into the neonatal CNS. J. Neurocytol., in press.
45. SHIHABUDDIN, L. S., J. A. HERTZ, V. R. HOLETS, AND S. R. WHITTEMORE. 1995. The adult CNS retains the potential to direct region-specific differentiation of a transplanted neuronal precursor cell line. J. Neurosci. 15: 6666-6678.
46. SMITH, L. M., C. F. HÖHMANN, AND F. F. EBNER. 1985. The development of specific cell types and connectivity in neocortical transplantation. Pages 249-255 in A. Björklund and U. Stenevi, Eds., Neural Grafting in the Mammalian CNS. Elsevier, Amsterdam.
47. SNYDER, E. Y., D. L. DEITCHER, C. WALSH, S. ARNOLD-ALDEA, E. A. HARTWIEG, AND C. L. CEPKO. 1992. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 66: 33-51.
48. SOTELO, C., AND R. M. ALVARADO-MALLART. 1986. Growth and differentiation of cerebellar suspensions transplanted into the adult cerebellum of mice with heredodegenerative ataxia. Proc. Natl. Acad. Sci. USA 83: 1135-1139.
49. SUNDE, N. A., AND J. ZIMMER. 1983. Cellular, histochemical and connective organization of the hippocampus and fascia dentata transplanted to different regions of immature and adult rat brains. Dev. Brain Res. 8: 165-191.
50. TONDER, N., T. SORENSEN, AND J. ZIMMER. 1989. Enhanced host perforant path innervation of neonatal dentate tissue after grafting to axon sparing ibotenic acid lesions in adult rats. Exp. Brain Res. 75: 483-496.
51. TONDER, N., T. SORENSEN, AND J. ZIMMER. 1990. Grafting of fetal CA3 neurons to excitotoxic, axon-sparing lesions of hippocampal CA3 area in adult rats. Prog. Brain Res. 83: 391-409.
52. TONDER, N., T. SORENSEN, J. ZIMMER, M. B. JORGENSEN, F. F. JOHANSEN, AND N. H. DIEMER. 1989. Neural grafting to ischemic lesions of the adult rat hippocampus. Exp. Brain Res. 74: 512-526.
53. WATANABE, T., AND M. C. RAFF. 1990. Rod photoreceptor development in vitro: Intrinsic properties of proliferating neuroepithelial cells change as development proceeds in the rat retina. Neuron 4: 461-467.
54. WHITTEMORE, S. R., AND E. Y. SNYDER. 1996. The physiological relevance and functional potential of central nervous system-derived neural cell lines. Mol. Neurobiol. 12: 13-38.
55. WHITTEMORE, S. R., AND L. A. WHITE. 1993. Target regulation of neuronal differentiation in a temperature-sensitive cell line derived from medullary raphe. Brain Res. 615: 27-40.
56. WHITTEMORE, S. R., L. A. WHITE, L. S. SHIHABUDDIN, AND M. J. EATON. 1995. Phenotypic diversity in neuronal cell lines derived from raphe nucleus by retroviral transduction. Methods 7: 285-296.
57. WICTORIN, K., AND A. BJÖRKLUND. 1989. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. II. Cortical afferents. Neuroscience 30: 297-311.
58. WICTORIN, K., D. J. CLARKE, J. P. BOLAM, AND A. BJÖRKLUND. 1990. Fetal striatal neurons grafted into the ibotenate lesioned striatum efferent projections and synaptic contacts in the host globus pallidus. Neuroscience 37: 301-315.
59. WICTORIN, K., R. B. SIMERLY, O. ISACSON, L. W. SWANSON, AND A. BJÖRKLUND. 1989. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. II. Efferent projecton neurons and their relation to host afferents within the grafts. Neuroscience 30: 313-330.